Diese Woche Neu TLRC Fakultät 2026
Woche 29 (13.07 - 19.07)
Phase 3 Study of Niraparib-Plus-Pembrolizumab as Maintenance Therapy for Advanced/Metastatic Non-Small Cell Lung Cancer (ZEAL-1L). Ramalingam SS, Velcheti V, Altan M, de Castro G Jr, Thomas M, Sanborn RE, Maziéres J, Schuler M, Isaksson J, Schenker M, Poddubskaya E, Kim YJ, Parakh S, Liu W, Neibauer MW, Aghera V, Chiu G, Peters S. J Thorac Oncol. 2026 Jul 10:104087. doi: 10.1016/j.jtho.2026.104087. Epub ahead of print. PMID: 42431263.
Consolidative Thoracic Radiotherapy With Atezolizumab Maintenance in Extensive-Stage Small Cell Lung Cancer: The Phase 2 TREASURE Randomized Clinical Trial (AIO-TRK-0320). Bozorgmehr F, Chung I, Behnisch R, Weykamp F, Adeberg S, Overbeck T, El Shafie R, Maguire N, Koerber SA, Buchmeier EL, Hammer-Hellmig M, Gauler T, Pöttgen C, Wermke M, Troost EGC, Kokowski K, Röper B, Reinacher-Schick A, Consdorf NS, Ulmer M, Müller AC, Wehler T, Hey-Koch S, Alt J, Stockinger M, Kuon J, Bischof M, Lamprecht B, Geinitz H, Lerchenmüller C, Kriz J, Rauter M, Raunik W, Schmidt B, Stupavsky A, Kropf-Sanchen C, Schmidtke-Schrezenmeier G, Wiegel T, Tufman A, Manapov F, Merling M, Heussel CP, Polke M, Reck M, Al-Batran SE, Thomas M, Christopoulos P, Rieken S. JAMA Oncol. 2026 Jul 9:e262330. doi: 10.1001/jamaoncol.2026.2330. Epub ahead of print. PMID: 42424047; PMCID: PMC13352179.
Does lung adenocarcinoma subtyping offer clinical benefits?-a retrospective population-based cohort study from Sweden. Zitricky F, Sundquist K, Sundquist J, Försti A, Hemminki A, Kaaks R, Hemminki K. Ann Transl Med. 2026 Jun 30;14(3):31. doi: 10.21037/atm-2026-0046. Epub 2026 Jun 29. PMID: 42434777; PMCID: PMC13349734.
msBayesImpute as a versatile framework for addressing missing values in biomedical mass spectrometry proteomics data. He J, Helm B, Gödtel F, Büchner K, Schilling M, Schneider MA, Klotz LV, Braunger J, Winter H, Velten B, Klingmüller U, Lu J. Commun Chem. 2026 Jul 7;9(1):236. doi: 10.1038/s42004-026-02106-3. PMID: 42414569; PMCID: PMC13342297.
Towards a standardized file format and open-source analysis framework for Brillouin microscopy data. Bevilacqua C, Hambura S, Bouvet P, Körbel M, La Cavera S 3rd, Elsayad K, Prevedel R. Nat Methods. 2026 Jul 10. doi: 10.1038/s41592-026-03164-0. Epub ahead of print. PMID: 42432223.
Woche 28 (06.07 - 12.07)
Outcomes of Platinum Plus Pemetrexed and Treatment Patterns Following First-Line Nivolumab and Ipilimumab in Pleural Mesothelioma: Real-World Results From the German MesoNet Study. Shah R, Buchmeier EL, Kopp HG, Griesinger F, Reck M, Christoph DC, Kuon J, Frost N, Grohé C, Faehling M, Saalfeld FC, Hoffknecht P, Luan J, Roeper J, Chesi P, Kimmich M, Olchers T, Klotz LV, Chung I, Thomas M, Christopoulos P. Clin Lung Cancer. 2026 Jul;27(6):68-74. doi: 10.1016/j.cllc.2026.06.001. Epub 2026 Jun 6. PMID: 42372417.
Beyond EML4: efficacy of targeted therapy in lung cancer patients with rare ALK fusions - a real-world retrospective analysis. Leßmann ME, Saalfeld FC, Ruge L, Kauffmann-Guerrero D, Illini O, Stenzinger A, Minuth-Fuchs K, Rittmeyer A, Goetting I, Schildknecht K, Eul B, Schubart C, Rothschild SI, Grohé C, Armster K, Mohorčič K, Janzic U, Waller CF, Overbeck TR, Vesce R, Schulte H, Mauti LA, Stephan-Falkenau S, Wiesweg M, Faehling M, Gerstenmaier U, Schmid S, Kian W, Lozynskyy R, Ivanović M, Syrigos K, Simon R, Merkelbach-Bruse S, Wenzel C, Brückmann S, Herold S, Aust DE, Thomas M, Hochmair MJ, Tufman A, Rasokat A; National Network Genomic Medicine Lung Cancer (nNGM); Christopoulos P, Wermke M. NPJ Precis Oncol. 2026 Jun 29;10(1):248. doi: 10.1038/s41698-026-01486-y. PMID: 42374111; PMCID: PMC13314944.
Body composition's effect on the bone-vascular axis of osteoporosis discovered in AI-based CT analysis of COPD patients. Budai BK, Wagner A, Havlicek O, Konietzke P, Trudzinski FC, Biederer J, Heußel CP, Kauczor HU, Palm V; COSYCONET study group. Eur Radiol. 2026 Jul 3. doi: 10.1007/s00330-026-12677-3. Epub ahead of print. PMID: 42399449.
Aim High-Stay Stable: Rethinking Treatment Success in COPD. Trinkmann F. Am J Respir Crit Care Med. 2026 Jul 3:aamag351. doi: 10.1093/ajrccm/aamag351. Epub ahead of print. PMID: 42398014.
How artificial intelligence could improve the diagnosis and management of COPD: a perspective from GOLD. Agusti A, Vila M, Faner R, Trinkmann F, Janssens W, Halpin DMG, Celli BR, Zheng J, Criner G, Aaron SD, Roche N, Fabbri L, Han M, Sin DD, Martínez FJ, Papi A, Troosters T, Anzueto A, Ozoh OB, Wedzicha J, Salvi S, Singh D, Montes de Oca M, Pavord I, Bourbeau J, Vogelmeier CF. Am J Respir Crit Care Med. 2026 Jun 30:aamag337. doi: 10.1093/ajrccm/aamag337. Epub ahead of print. PMID: 42377276.
Molecular Tumor Board-Guided Osimertinib Therapy in EGFR L858R/Q701L-Mutant Lung Adenocarcinoma Supported by Functional Validation. Albers-Leischner C, Ritgen M, Paulsen FO, Schmidt B, von Bubnoff N, Gorantla SP, Letsch A, Janning M, Loges S, Bokemeyer C, Christopeit M. Oncologist. 2026 Jul 2:oyag242. doi: 10.1093/oncolo/oyag242. Epub ahead of print. PMID: 42391607.
A Response to the Letter to the Editor: Population-informed Assessment of Clonality in Lung Cancer. Allgäuer M, Kluck K, Kazdal D, Budczies J, Stenzinger A, Kirchner M. J Thorac Oncol. 2026 Jul;21(7):103725. doi: 10.1016/j.jtho.2026.103725. PMID: 42399015.
Prevalence and characteristics of NTRK fusions in 25,946 patients with non-small cell lung cancer. Radonic T, Rahmani-Khajouei S, Dafni U, Stenzinger A, Haberecker M, Madsen LB, Monkhorst K, Kowalski J, Hernandez-Losa J, Kerr KM, Speel EJM, Bubendorf L, Joseph L, Navarro A, Thunnissen E, Sansano I, Hillen LM, Biernat W, Christoffel M, Tsamtsouri L, Kammler R, Peters S, Zoche M, Stahel RA, Finn SP; ETOP Lungscape consortium. Lung Cancer. 2026 Jun 28;218:109514. doi: 10.1016/j.lungcan.2026.109514. Online ahead of print. PMID: 42385495
Recruitment strategies for lung cancer screening; a randomised trial in the 4-IN-THE-LUNG-RUN study. Hubert J, Moldovanu D, van den Bosch I, Katzke V, Kaaks R, Espinàs JA, Taube C, Pastorino U, Garcia G, Baldwin DR, Oudkerk M, de Koning HJ, van der Aalst CM. Lung Cancer. 2026 Jun 24;218:109509. doi: 10.1016/j.lungcan.2026.109509. Epub ahead of print. PMID: 42372381.
Woche 27 (29.06 - 05.07)
Spatial proteomics profiling reveals oncogene-specific immune niches and prognostic markers in NSCLC. Nandigama R, Cheikh BB, Wilhelm J, Nikulina N, Klotz LV, Nabhanizadeh J, Kriegsmann M, Bartkuhn M, Looso M, Jhaveri N, Braubach O, Stenzinger A, Reck M, Grimminger F, Seeger W, Pullamsetti SS, Weigert A, Stiewe T, Winter H, Savai R. Am J Respir Crit Care Med. 2026 Jun 26:aamag330. doi: 10.1093/ajrccm/aamag330. Epub ahead of print. PMID: 42363408.
Quantitative Analysis of Bronchiectasis in Alpha-1 Antitrypsin Deficiency. De Soyza J, Höger P, Ellis P, Weinheimer O, Trudzinski F, Turner AM. Can Respir J. 2026;2026(1):e5419612. doi: 10.1155/carj/5419612. PMID: 42340139; PMCID: PMC13292108.
Social media activities to enhance the visibility of long-term invasive ventilation: A content and visibility analysis from the PRiVENT study. Trudzinski FC, Litke N, Buntemeyer O, Janssen S, Biehler E, Fleischhauer T, Dahlhoff JC, Höger P, Kempa A, Neetz B, Joves B, Neurohr C, Ghiani A, Schneider A, Szecsenyi J, Meis J, Schubert-Haack J, Michels-Zetsche JD, Herth FJ; and the PRiVENT-Study Group. PLoS One. 2026 Jun 25;21(6):e0352267. doi: 10.1371/journal.pone.0352267. PMID: 42348533; PMCID: PMC13298930.
Unveiling tumor heterogeneity by single cell RNA-sequencing: from basic considerations to clinical applications. Fuchs T, Menzel M, Mößinger K, Kazdal D, Kahles A, Budczies J, Stenzinger A. Semin Cancer Biol. 2026 Jun 28:S1044-579X(26)00061-1. doi: 10.1016/j.semcancer.2026.06.005. Epub ahead of print. PMID: 42365863.
New biomarkers for antibody-drug conjugates in lung cancer the pathologist's perspective. Hofman V, Rignol G, Mograbi B, Ilié M, Riudavets M, Lopez-Rios F, Fusco N, Malapelle U, Popat S, Stenzinger A, Planchard D, Passaro A, Heeke S, Peters S, Wistuba II, Hirsch FR, Hofman P. Lung Cancer. 2026 Jun 23;218:109507. doi: 10.1016/j.lungcan.2026.109507. Epub ahead of print. PMID: 42364305.
Switching Biologics in Severe Asthma: Cautionary Lessons from NIMBLE. Godbout K, Herth FJF, Charriot J, Bourdin A, Caminati M. Am J Respir Crit Care Med. 2026 Jun 24:aamag295. doi: 10.1093/ajrccm/aamag295. Epub ahead of print. PMID: 42340678.
The Smokerface poster campaign for adolescent smoking prevention in schools: A cluster-randomized controlled trial. Wies C, Messner J, Merl NB, Winterstein JT, Kommoss K, Jakob L, Fahrner HM, Heckl M, Cirac A, Suhre JL, Fries FN, Spielmann H, Seeger W, Herth F, Groneberg DA, Gall H, Bauer-Kemeny C, Taha L, Kreuter M, Fröhling S, Mons U, Brinker TJ. Eur J Cancer. 2026 Jun 19;244:116898. doi: 10.1016/j.ejca.2026.116898. Epub ahead of print. PMID: 42330568.
Woche 26 (22.06 - 28.06)
Radiologists' memory as a data protection risk: a worst-case stress test for chest radiograph re-identification. Fink MA, Römer C, Ebel M, Frodl E, Dos Santos DP, Kauczor HU, Bucher A. Insights Imaging. 2026 Jun 16;17(1):162. doi: 10.1186/s13244-026-02336-y. PMID: 42301366; PMCID: PMC13272688.
Incidental Pulmonary Nodules: What Should We Do in 2026? Schmid-Bindert G, Vogel-Claussen J, Bollmann BA, Lamché J, Eichhorn ME, Herth F. Respiration. 2026;105(6):673-684. doi: 10.1159/000549849. Epub 2025 Dec 9. PMID: 41363795; PMCID: PMC12818888.
Functional characterization of KCNA5 gene variants linked to pulmonary arterial hypertension. Csáki R, Foris V, Eichstaedt CA, Almássy J, Dobolyi A, Nagaraj C, Tóth B, Halank M, Grünig E, Hinderhofer K, Klose H, Milger K, Olsson KM, Seyfarth HJ, Tello K, Olschewski H, Olschewski A, Enyedi P. Eur Respir J. 2026 Jun 18:2600429. doi: 10.1183/13993003.00429-2026. Epub ahead of print. PMID: 42315184.
Learning Curve for Transbronchial Lung Cryobiopsy in Interstitial Lung Disease Diagnosis: A Multicenter Experience. Tong R, Guo S, Xia Y, Li Y, Zhou G, Xu W, Su Y, Deng M, Porcel JM, Herth FJF, Hou G. Respiration. 2026 Jun 16:1-17. doi: 10.1159/000553097. Epub ahead of print. PMID: 42301995.
Remission in Global Airway Diseases: EUFOREA Consensus Paper. Virchow JC, Bertels X, Backer V, Bleier BS, Caminati M, Conti DM, De Corso E, Gaga M, Lund VJ, Pelaia C, Peters AT, Scadding GK, Wagenmann M, Al-Lehebi RO, Brusselle GG, Gevaert P, Heaney LG, Lee SE, Schleich F, Trinkmann F, Hellings PW, Fokkens WJ, Rogliani P. Allergy. 2026 Jun 16. doi: 10.1111/all.70415. Epub ahead of print. PMID: 42304188.
Comparison of three commercial AI tools for detection and malignancy assessment of incidental lung nodules. Tokur O, von Stackelberg O, Dulz L, Budai BK, Debic M, Wei N, Heussel CP, Kauczor HU, Wielpütz MO. Front Med (Lausanne). 2026 Jun 3;13:1806511. doi: 10.3389/fmed.2026.1806511. PMID: 42318386; PMCID: PMC13272353.
Follow-Up Care After Adult Lung Transplantation: Summary of an Evidence-Based Clinical Practice Guideline for German-Speaking Countries. Gottlieb J, Wald A, Bucher B, Tapp B, Hirsch C, Schneider C, Winter H, Wilkens H, Geldmacher H, Hettich I, Jaksch P, Schuurmans MM, Schiffer M, Hecker M, Nothacker M, Skoetz N, Kreuzberger N, Witzke O, Schmitt R, Jörger-Tuti S, Bessa V, Veit W, Taube C, Kneidinger N. Respiration. 2026 Jun 16:1-27. doi: 10.1159/000553086. Epub ahead of print. PMID: 42301957.
Woche 25 (15.06 - 21.06)
Robotic Bronchoscopy and Lung Cancer Stage Shift: Hype or Hope? Brock JM, van der Heijden EHFM, Herth FJF. Chest. 2026 Jun;169(6):1462-1463. doi: 10.1016/j.chest.2025.11.032. PMID: 42264571.
Plasma PlGF as a Potential Biomarker in Ramucirumab-Based Second-Line Therapy for Advanced Gastroesophageal Adenocarcinoma: Exploratory Biomarker Analysis from the Phase II Part of the RAMIRIS Trial. Hille J, Lorenzen S, Pauligk C, Gensch V, Thuss-Patience P, Goekkurt E, Ettrich T, Lordick F, Bokemeyer C, Müller C, Reichardt P, Sökler M, Pink D, Probst S, Goetze TO, Al-Batran SE, Loges S, Janning M. Int J Cancer. 2026 Jun 9. doi: 10.1002/ijc.70567. Epub ahead of print. PMID: 42266015.
Tularemia With Necrotizing Mediastinal Lymph Nodes. Grott M, Winter H, Mager L, Stacher-Priehse E, Hatz R, Haag J. Ann Thorac Surg Short Rep. 2025 Dec 17;4(2):513-515. doi: 10.1016/j.atssr.2025.11.022. PMID: 42267027; PMCID: PMC13245286.
Woche 24 (08.06 - 14.06)
Longitudinal Changes in Lung Morphology and Perfusion Detected by Magnetic Resonance Imaging in Patients with Primary Ciliary Dyskinesia From Infancy Through Adulthood. Wucherpfennig L, Silani MS, Eichinger M, Triphan SMF, Stahl M, Graeber SY, Thee S, Urbantat RM, Döllinger F, Hämmerling S, Sommerburg O, Schenk JP, Alrajab A, Heussel CP, Wege S, Kauczor HU, Wielpütz MO, Mall MA. Chest. 2026 Jun 4:S0012-3692(26)00653-7. doi: 10.1016/j.chest.2026.05.020. Epub ahead of print. PMID: 42248298.
Advances in Diagnosis-Pulmonology. Stone E, Hu X, Afriyie-Mensah JS, Lee P, Herth F, Brock J, Yasufuku K, Ishiwata T, Rahman N, Addala D, Shivakumar S, Yeo S, Leong TL. J Thorac Oncol. 2026 Jun;21(6):103648. doi: 10.1016/j.jtho.2026.103648. PMID: 42250919.
Lung Cancer Patients Display Increased Expression of Bovine Meat and Milk Factor (BMMF) Proteins in Peritumor Alveolar Macrophages. Cecere N, Alikhanyan K, Ernst C, Häfele L, Feuerbach L, Grewe I, Siqin S, Gunst K, Shukla G, Frehtman V, Tessmer C, Eichhorn F, Allgäuer M, Brobeil A, Hofmann I, Leuchs B, Schneider MA, Bund T. Int J Cancer. 2026 Jun 1. doi: 10.1002/ijc.70574. Epub ahead of print. PMID: 42226376.
Das Internet als Informationsquelle für Patientinnen und Patienten mit Sarkoidose [The internet as a source of information for patients with sarcoidosis]. Buschulte K, Höger P, El-Hadi S, Ganter C, Kahn N, Kriegsmann K, Wilkens FM, Polke M, Trudzinski F, Herth F, Kreuter M. Pneumologie. 2026 Jun 2. German. doi: 10.1055/a-2868-0156. Epub ahead of print. PMID: 42229457.
EGFR deletion in myeloid cells reprograms the immunosuppressive landscape of colorectal cancer. Fari O, Neuhofer A, Holcmann M, Chontorotzea T, Barozzi I, Mohr T, Blauensteiner B, Krauß D, Xiao YT, Lang M, Frey DL, Helm B, Klingmüller U, Farlik M, Sibilia M. Cell Death Differ. 2026 Jun 2. doi: 10.1038/s41418-026-01774-x. Epub ahead of print. PMID: 42230982.
Embedding equity in Germany's National Lung Cancer Screening roll-out: a call to action. Baltaci E, Loges S, Mavila AD, Hoe C. Lancet Oncol. 2026 Jun;27(6):669-672. doi: 10.1016/S1470-2045(26)00253-6. PMID: 42225100.
Ensuring continued access to essential inhaled respiratory medications: a call to action from the Inhaled Respiratory medicine Innovation and environmental Sustainability (IRIS) group. Hurst JR, Kaplan A, van Boven JFM, Bhutani M, Han MK, Paulino E, Russell REK, Sawyer M, Trudzinski FC, van Ravenzwaay B, Winders T, Yorgancioglu A. Eur Respir J. 2026 Jun 4;67(6):2501873. doi: 10.1183/13993003.01873-2025. PMID: 42242746; PMCID: PMC13234408.
Woche 23 (01.06 - 07.06)
Who labels best? Radiologists, rules, or large language models for CT reports on pulmonary embolism. Fink MA, Bischoff A, Atsiatorme E, Kremer A, Kroschke J, Moll M, Stein P, Riebl V, Leichenich T, Kauczor HU, Schlamp K. Eur Radiol Exp. 2026 May 27;10(1):74. doi: 10.1186/s41747-026-00738-7. PMID: 42201590; PMCID: PMC13216375.
How green are large language models for radiology report labelling? Comparing human, rule-based and hybrid workflows. Fink MA, Bischoff A, Atsiatorme E, Kremer A, Kroschke J, Moll M, Stein P, Riebl V, Leichenich T, Kauczor HU, Schlamp K. Insights Imaging. 2026 May 27;17(1):142. doi: 10.1186/s13244-026-02289-2. PMID: 42201579; PMCID: PMC13216412.
Pulmonary Actinomycosis: A Hidden Threat with Clinical Impact. Griffo R, Jasuja JK, Niedermaier B, Wege S, Shala J, Deissner H, Brendel L, Rösch RM, Eichhorn F, Allgäuer M, Tong E, Wimmer C, Eichhorn ME, Winter H, Klotz LV. Adv Respir Med. 2026 May 18;94(3):33. doi: 10.3390/arm94030033. PMID: 42201236; PMCID: PMC13214486.
e-Lung computed tomography biomarkers are associated with outcomes in fibrotic interstitial lung diseases. Abbasi Dezfouli K, Devaraj A, Ottink FA, Rennison-Jones C, Sifostratoudaki A, Fernandez C, von Stackelberg O, Kauczor HU, Debic M, Schlamp K, Buschulte K, Heussel CP, Briggs JH, Gerry S, Harston GWJ, Bou-Zeid W, Joly O, George PM, Kreuter M. ERJ Open Res. 2026 May 26;12(3):01058-2025. doi: 10.1183/23120541.01058-2025. PMID: 42206014; PMCID: PMC13202359.
Large-scale association study identifies lung cancer susceptibility copy number variants and their potential functional role in genetic instability. Xiao F, Qin F, Luo X, Slewitzke SE, Fernandes GF, Johansson M, Xiao X, Zaridze D, Bojesen SE, Shete S, Albanes D, Aldrich MC, Tardon A, Fernandez-Tardon G, Le Marchand L, Rennert G, Bickeböller H, Wichmann HE, Risch A, Muley T, Rosenberger A, Field JK, Davies M, Woll P, Kiemeney LA, Haugen A, Zienolddiny S, Lam S, Johansson M, Grankvist K, Schabath MB, Andrew A, Lazarus P, Arnold SM, Zhu D, Brenner H, Neuhouser ML, Hung RJ, Christiani DC, McKay J, Cai G, Xia J, Amos CI. medRxiv [Preprint]. 2026 May 15:2026.05.11.26352741. doi: 10.64898/2026.05.11.26352741. PMID: 42180356; PMCID: PMC13193147.
Woche 22 (25.05 - 31.05)
Differential effects of prior versus concomitant Steroid and Antibiotic Treatment on Immunotherapy Efficacy - A Pooled Analysis of the RAMONA, INTEGA, OPTIM, ELDORANDO, FORCE, TITAN-RCC and TITAN-TCC Trials of the German AIO Study Group. Wiest IC, Dreikhausen L, Keller R, Marin-Galiano M, Albiges L, Meran J, Leucht K, Rieken S, Esteban E, Zengerling F, Tintelnot J, Grimm MO, Bozorgmehr F, Christopoulos P, Stein A, Binder M, Härtel N, Klinghammer K, Grünwald V, Pogorzelski M, Ebert MP. Br J Cancer. 2026 May 19. doi: 10.1038/s41416-026-03428-8. Epub ahead of print. PMID: 42156980.
Internal Radiation Therapy. Haberkorn U, Kratochwil C, Mamlins E, Mori Y, Giesel FL. Recent Results Cancer Res. 2026;225:1015-1042. doi: 10.1007/978-3-032-21415-7_16. PMID: 42165840.
68Ga-FAPI-PET/CT in extra-cervical CUP: Head-to-Head Comparison of 68Ga-FAPI-46 with 18F-FDG in 13 patients. Spektor AM, Zapata Bonilla SA, Mildenberger P, Kilburg A, Driess D, Winter E, Kloth M, Schreckenberger M, Bäuerle T, Kindler T, Haberkorn U, Pouyiourou M, Krämer A, Bochtler T, Röhrich M.Eur J Nucl Med Mol Imaging. 2026 May 22. doi: 10.1007/s00259-026-07916-0. Epub ahead of print. PMID: 42171731.
The MYB-related transcription factor MYPOP acts as a selective regulator of cancer cell growth. Strunk J, Hüppner A, Sial M, Plath M, Sheriff MB, Wagner S, Freitag K, Mikuličić S, Döring T, Bopp T, Klein M, Rajalingam K, Harms G, Marini F, Nedwed AS, Hankeln T, Osterhof C, Schneider MA, Henrich A, Nubbemeyer A, Suchan M, Brill S, Perkovic M, Schrörs B, Kreiter S, Kölsch A, Diken M, Florin L. Commun Biol. 2026 May 19;9(1):678. doi: 10.1038/s42003-026-10272-2. PMID: 42156885; PMCID: PMC13187161.
Comparison of PD-L1 expression between biopsy specimens and surgical resection specimens in non-small cell lung cancer: a meta-analysis. Zhou R, Yang H, Herth FJF, Zhang X, Kong D.Clin Transl Oncol. 2026 May 24. doi: 10.1007/s12094-026-04420-7. Epub ahead of print. PMID: 42177725.
ERS/ESGE/ESTS clinical practice guidelines on endobronchial and oesophageal endosonography for the diagnosis and staging of lung cancer. Korevaar DA, Kovacevic B, Papadopoulou E, van den Broek FJC, Bertolaccini L, Catarata MJ, Denswil NP, Facciorusso A, Gnass M, Gompelmann D, Herth FJF, Kontogianni K, Koukaki E, Marc-Malovrh M, Simon M, Moretti A, Novoa NM, Seicean A, Tsang NNY, Demonceau C, Tonia T, Sanz-Santos J, Konge L, Vilmann P, Annema JT. Eur Respir J. 2026 May 21:2600097. doi: 10.1183/13993003.00097-2026. Epub ahead of print. PMID: 42167778.
Safety and efficacy of astegolimab for COPD with frequent exacerbations regardless of baseline blood eosinophil counts (ALIENTO and ARNASA): randomised, double-blind, placebo-controlled, phase 2b and 3 trials. Papi A, Greening NJ, Bhatt SP, Roche N, Celli B, Wedzicha JA, Agustí À, Tal-Singer R, Han MK, Janssens W, Hanania NA, Nair P, Bremner P, Porpodis K, Shibata Y, Korn S, Yang T, Gordon O, Saenz R, Ng J, Cheung DS, Devine J, Grimbaldeston MA, Zhang W, Yang X, Mohan D, Vogelmeier CF, Brightling CE; ALIENTO and ARNASA investigators. Lancet. 2026 May 23;407(10543):2027-2039. doi: 10.1016/S0140-6736(26)00637-9. Epub 2026 May 18. PMID: 42150581.
Woche 21 (18.05 - 24.05)
Functional Precision Oncology Approach Using Nanoliter Droplet Array for Drug Sensitivity Testing in Lung Cancer. Salarian M, Schiling VL, Muley T, Allgäuer M, Eichhorn F, Meister M, Schneider MA, Popova AA. Adv Healthc Mater. 2026 May 15:e03761. doi: 10.1002/adhm.202503761. Epub ahead of print. PMID: 42138089.
Small airways disease is common in mild COPD and symptomatic subjects at risk with normal spirometry: baseline data from CAPTO-COPD. Trinkmann F, Abdo M, Herth FJF, Rabe KF, Kirsten AM, Watz H. ERJ Open Res. 2026 Apr 27;12(2):00185-2025. doi: 10.1183/23120541.00185-2025. PMID: 42111372; PMCID: PMC13152375.
Tumor microenvironment evolution in lung cancer: Spatio-temporal dynamics and clinical implications. Dizdarević S, Timofeev O, Kazdal D, Pullamsetti SS, Sotillo R, Loges S, Kobold S, Stenzinger A, Stiewe T, Savai R. Semin Cancer Biol. 2026 May 15;123-124:1-26. doi: 10.1016/j.semcancer.2026.04.003. Epub ahead of print. PMID: 42114663.
Natural killer cell immunotherapy reverses lung fibrosis by eliminating senescent fibroblasts. Merkt W, Rodon L, Deicher FS, Freitag M, Claus M, Lister R, Han H, Zhou Y, Horne A, Stütz A, Li YN, Kreuter M, Kahn N, Schneider MA, Egea-Zorrilla A, Blasco-Iturri Z, Nikulina N, Turkowski K, Ruppert C, Guenther A, Rizzo R, Rizzo S, Ferraresi M, Hübschmann D, Haas S, Blank N, Watzl C, Tykocinski LO, Lorenz HM, Savai R, Pardo-Saganta A, Lagares D. Sci Transl Med. 2026 May 13;18(849):eadq5442. doi: 10.1126/scitranslmed.adq5442. Epub 2026 May 13. PMID: 42127218.
Exploring the bone-vascular axis: AI-augmented chest CT analysis in COPD highlights association between vertebral bone density and arterial calcifications. Palm V, Wagner A, Havlicek O, Sedaghat S, Nauck S, von Stackelberg O, Jobst B, Trudzinski FC, Kahnert K, Biederer J, Kauczor HU, Budai BK; COSYCONET study group. Respir Med. 2026 May 11;258:108888. doi: 10.1016/j.rmed.2026.108888. Epub ahead of print. PMID: 42119926.
Woche 20 (11.05 - 17.05)
Artificial Intelligence Improves Chest X-ray Interpretation Employing Magnetic Resonance Imaging as Ground Truth in Patients with Cystic Fibrosis. Zhao S, Wucherpfennig L, Kou Y, Triphan SMF, Ringwald FG, Mall MA, Stahl M, Sommerburg O, Eisenmann U, Knaup-Gregori P, Wielpütz MO. Am J Respir Crit Care Med. 2026 May 4:aamag146. doi: 10.1093/ajrccm/aamag146. Epub ahead of print. PMID: 42089677.
Prognosis and aetiology of hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) in patients with active lung or lower head and neck cancer (PEPP-C): a retrospective, matched multicentre cohort study in Germany and Spain. Pütz SM, Engelhard M, Wingen-Heimann SM, Brilz DF, Akrich B, Kohl H, Classen AY, Gudiol C, Sastre-Escola E, Trudzinski FC, Rivera AO, Lücke E, Marczewski T, Daher A, Eisenmann S, Schmitz J, Reinacher-Schick A, von Tresckow J, Mispelbaum R, Hattenhauer T, Vehreschild JJ.Infection. 2026 May 4. doi: 10.1007/s15010-026-02805-y. Epub ahead of print. PMID: 42081049.
First European Results of Shape-Sensing Robotic-Assisted Bronchoscopy. Brock JM, Dittrich AS, Kontogianni K, Heussel CP, Klotz LV, Winter H, Schellenberg M, Keppler U, Herth F. Respiration. 2026;105(5):599-607. doi: 10.1159/000549197. Epub 2025 Nov 7. PMID: 41201985.
Whitepaper zu Identifikation, Information und Eignungsprüfung von potenziellen Teilnehmern an der Lungenkrebsfrüherkennung in Deutschland [White paper on identification, information, and eligibility assessment of potential participants in lung cancer screening in Germany]. Blum TG, Vogel-Claussen J, Hoffmann H, Reck M, Harth V, Faron A, Dänschel I, Andreas S, Rupp A, Kaaks R, Schmid-Bindert G. Pneumologie. 2026 May;80(5):375-384. German. doi: 10.1055/a-2697-6434. Epub 2025 Oct 14. Erratum in: Pneumologie. 2026 May;80(5):e1. doi: 10.1055/a-2748-2597. PMID: 41086827.
Deep Learning-Based Quality Control and Diagnosis of Bronchial Images. Zhou Y, Herth FJF, Liu B, Li F, Ruan C, Cai H, Li Y, Li J. Respiration. 2026;105(5):617-626. doi: 10.1159/000548342. Epub 2025 Nov 27. PMID: 41308068.
Woche 19 (04.05 - 10.05)
A Retrospective, Multicenter Analysis Within the National Network Genomic Medicine Lung Cancer in Germany to Detect RET Fusions as a Possible Mechanism of Resistance in Patients With EGFR Mutations. Kropf-Sanchen C, Frost N, Kuon J, Wermke M, Krüger S, Fuchs F, Wiesweg M, Christopoulos P, Thomas M, Gaisa NT, Josten M, Wenzel C, Buth J, Glanemann F, Stenzinger A, Froelich MF, Janning M, Colienne M, Haselmann V, Loges S. Clin Lung Cancer. 2026 Mar 18:S1525-7304(26)00039-2. doi: 10.1016/j.cllc.2026.03.005. Epub ahead of print. PMID: 42055889.
Smoking history, eligibility for lung cancer screening and risk of death by lung cancer or other causes -- a longitudinal, time-variable analysis of the EPIC-Heidelberg cohort. Chen Y, Dutta S, Bajracharya R, Cortès-Ibañez F, Fortner RT, Katzke V, Kaaks R. BMC Med. 2026 Apr 28;24(1):274. doi: 10.1186/s12916-026-04891-z. PMID: 42050626; PMCID: PMC13126791.
Minimally invasive extracorporeal CO2 removal in hypercapnic respiratory failure: a prospective observational study. Kryvenko V, Husain-Syed F, Schnell E, Oruqaj G, Morty RE, Herold S, Hecker M, Tello K, Seeger W, Vadász I. Crit Care. 2026 Apr 30;30(1):224. doi: 10.1186/s13054-026-06062-1. PMID: 42057044; PMCID: PMC13130721.
Investigating sarcopenia and mucus plugging by chest computed tomography in patients with severe chronic obstructive pulmonary disease. Petersen A, Hübner RH, Mall MA, Steffen IG, Weinheimer O, Witzenrath M, Saccomanno J, Elgeti T. Sci Rep. 2026 Apr 28;16(1):13762. doi: 10.1038/s41598-026-49060-7. PMID: 42049798; PMCID: PMC13129093.
Woche 18 (27.04 - 03.05)
Neoadjuvant Atezolizumab and Chemotherapy for Non-Squamous Non-Small Cell Lung Cancer: Efficacy and Safety Results of an Open-Label, Single-Arm, Phase II Trial. Niedermaier B, Bochtler T, Eichhorn F, Griffo R, Klotz LV, Allgäuer M, Stenzinger A, Bischoff H, Schneider MA, Christopoulos P, Haberkorn U, Heussel CP, Zoernig I, Herth FJF, Thomas M, Rölle A, Winter H, Benner A, Jaeger D, Eichhorn ME. Int J Cancer. 2026 Apr 19. doi: 10.1002/ijc.70508. Epub ahead of print. PMID: 42003237.
Association of blood eosinophils and exhaled nitric oxide with exacerbations in patients with asthma, COPD and asthma+COPD: the NOVELTY study. Muiser S, Müllerová H, Belton L, Rusibamayila N, Erhard C, Agusti A, Faner R, Pavord I, Couillard S, Inoue H, Price DB, Olaguibel JM, Kerstjens HAM, van den Berge M; NOVELTY Scientific Community; NOVELTY study investigators. Thorax. 2026 Apr 21:thorax-2025-223646. doi: 10.1136/thorax-2025-223646. Epub ahead of print. PMID: 42014196.
Woche 17 (20.04 - 26.04)
Treatment Patterns, Outcome, and Quality of Life of Patients With Extensive-Stage SCLC Receiving Third-Line Therapy-Data From the German CRISP Registry (AIO-TRK-0315): A Brief Report. Rost M, Fischer R, Reck M, Gauler T, Waller C, Christopoulos P, Hoffknecht P, Jänicke M, Fleitz A, Härzschel A, Lennartz C, Ludwig P, Groth A, Bendel M, Stratmann J, Griesinger F, Thomas M, Eberhardt WEE, Sebastian M. JTO Clin Res Rep. 2026 Jan 24;7(4):100959. doi: 10.1016/j.jtocrr.2026.100959. PMID: 41969361; PMCID: PMC13066948.
FDG-PET/CT based small volume accelerated immuno chemoradiotherapy in locally advanced NSCLC (PACCELIO) - a randomized, open-label, multicenter phase II trial protocol. Shafie RE, Willmann J, Gkika E, Schimek-Jasch T, Miederer M, Bozorgmehr F, Griesinger F, Manapov F, Christopoulos P, Hehr T, Hecht M, Bütof R, Stuschke M, Guckenberger M, Schmid-Bindert G, Meiners J, Herzer S, Hartmann S, Lamché J, Rieken S, Nestle U. BMC Cancer. 2026 Apr 17;26(1):494. doi: 10.1186/s12885-026-15901-x. PMID: 41992146; PMCID: PMC13088629.
Distinct long-term effects on lung function and airway remodeling in ovalbumin and house dust mite mouse models of experimental asthma. Markus MA, Albers J, Alves F, Dullin C. Sci Rep. 2026 Apr 18;16(1):12737. doi: 10.1038/s41598-026-47822-x. PMID: 42000816; PMCID: PMC13091909.
Digital twin-based bronchoscopy simulator improves training performance and skill retention of novices: a randomised controlled study. Deng M, Li F, Tang F, Chen W, Wang F, Tang CL, Tong R, Yang Z, Xu W, Zhang N, Xia Y, Li S, Herth FJF, Hou G.Thorax. 2026 Apr 16;81(5):483-491. doi: 10.1136/thorax-2025-223147. PMID: 41207791.
First-In-Human Trial of the Implantable Artificial Bronchus: A Novel Bronchoscopically Delivered Treatment Option for Patients with Severe Emphysema. de Oliveira HG, Slebos DJ, Herth F. Respiration. 2026;105(4):527-537. doi: 10.1159/000548873. Epub 2025 Oct 13. PMID: 41082472.
Ferritin and transferrin predict common carotid intima-media thickness in females: a machine-learning informed individual participant data meta-analysis. Ruban Agarvas A, Sparla R, Atkins JL, Altamura C, Anderson T, Asicioglu E, Bassols J, López-Bermejo A, Dvořáková HM, Fernández-Real JM, Hochmayr C, Knoflach M, Milicevic JK, Lai S, Moreno-Navarrete JM, Pawlak D, Pawlak K, Syrovatka P, Formanowicz D, Kraml P, Valdivielso JM, Valenti L, Muckenthaler MU. BMC Cardiovasc Disord. 2026 Apr 14. doi: 10.1186/s12872-026-05796-8. Epub ahead of print. PMID: 41981480.
Woche 16 (13.04 - 19.04)
How medicine has changed over time, sex, money and work life balance. Herth FJF. Respiration. 2026 Apr 7:1-8. doi: 10.1159/000551879. Epub ahead of print. PMID: 41945478.
Procedural Techniques, Airway Management and Specimen Acquisition for Peripheral Lung Transbronchial and Endobronchial Ultrasound Guided Cryobiopsy: A Modified Delphi Consensus Statement. Beattie JA, Kapp CM, Thiboutot J, Aboudara MC, Akulian J, Argento AC, Casal RF, Cheng G, De Cardenas J, DeMaio A, Diez-Ferrer M, Fan Y, Gonzales AV, Herth F, Husta B, Ji W, Kagima JW, Keyes C, Kim YW, Liberman M, Majid A, Navani N, Oberg CL, Poletti V, Seides BJ, Silvestri G, Wahidi M, Yu DH, Maldonado F, Feller-Kopman D, Yarmus LB, Gilbert CR; Interventional Pulmonary Outcomes Group. Chest. 2026 Apr 7:S0012-3692(26)00436-8. doi: 10.1016/j.chest.2026.03.027. Epub ahead of print. PMID: 41956150.
Differential KEAP1/NRF2 mediated signaling widens the therapeutic window of redox-targeting drugs in SCLC therapy. Samarin J, Nůsková H, Fabrowski P, Malz M, Amtmann E, Taeubert MJ, Pastor-Flores D, Kazdal D, Kurilov R, de Vries N, Pink H, Deis F, Hummel-Eisenbeiss J, Renz L, Kaushal K, Morgen M, Dick TP, Hamilton G, Muckenthaler M, Mall M, Lim B, Kanamaru T, Klinke G, Sos ML, Frede J, Miller AK, Alborzinia H, Gunkel N. Nat Commun. 2026 Apr 12;17(1):3435. doi: 10.1038/s41467-026-71608-4. PMID: 41965332.
A metabolomics and lipidomics atlas of pulmonary large cell neuroendocrine carcinoma. Tietzova I, Hricko J, Rancourt RC, Schneider MA, Allgäuer M, Cajka T. Biomed Pharmacother. 2026 Apr 7;198:119327. doi: 10.1016/j.biopha.2026.119327. Epub ahead of print. PMID: 41950604.
Woche 15 (06.04 - 12.04)
MRI for Lung Cancer Management: Any Closer to Clinical Application? J Magn Reson Imaging. Biederer J, Bergmann LL, Ackman JB, Hochhegger B, Azour L, Triphan SMF, Dinkel J, Ohno Y, Ozawa Y, van Beek EJR, Wucherpfennig L. 2026 Apr 3. doi: 10.1002/jmri.70308. Epub ahead of print. PMID: 41928658.
Dyspnoe bei invasiv beatmeten Patientinnen und Patienten: eine Übersicht [Dyspnoea in invasively ventilated patients: an overview]. Neetz B, Höger P, Kaestner F, Herth F, Trudzinski F. Pneumologie. 2026 Mar 30. German. doi: 10.1055/a-2809-4045. Epub ahead of print. PMID: 41911689.
Shape-Sensing Robotic-Assisted Bronchoscopic Cryoablation for Primary and Metastatic Pulmonary Nodules: Feasibility, Safety, and Early Outcomes. Xu L, Gu W, Zhao M, Lin G, Van Nostrand K, Patel NM, Duchman B, Tran BD, Munoz-Pineda JA, Miller RJ, Herth FJ, Cheng G. Respiration. 2026 Mar 30:1-23. doi: 10.1159/000551795. Epub ahead of print. PMID: 41911076.
Bridging the gap between tumor evolution and clonality diagnostics in multiple lung carcinomas. Janssen J, Allgäuer M, Ylstra B, Draijer S, Kim Y, Budczies J, Kazdal D, Stenzinger A, Kirchner M, Radonic T. Semin Cancer Biol. 2026 Mar 28;122:1-15. doi: 10.1016/j.semcancer.2026.03.003. Epub ahead of print. PMID: 41912125.
Time dependent outcomes modeling in a real-world analysis of the molecular tumor board at university cancer center Hamburg (2016-2022). Velthaus-Rusik JL, Weller JF, Hoshaber M, Schmidt B, Albers-Leischner C, Kriegs M, Loges S, Bartels S, Schlüter C, Simon R, Volk AE, Kubisch C, Ückert F, Riemann L, Weisel K, von Amsberg G, Alsdorf W, Bokemeyer C, Christopeit M.Oncologist. 2026 Mar 31:oyag078. doi: 10.1093/oncolo/oyag078. Epub ahead of print. PMID: 41920942.
Systemic effects of cystic fibrosis transmembrane conductance regulator modulators on the plasma and serum proteome. Fentker K, Kirchner M, Ziehm M, Niquet S, Popp O, Duerr J, Schaupp L, Roehmel J, Thee S, Hämmerling S, Sommerburg O, Stahl M, Graeber SY, Mall MA, Mertins P. Cell Syst. 2026 Apr 1:101569. doi: 10.1016/j.cels.2026.101569. Epub ahead of print. PMID: 41928517.
Woche 14 (30.03 - 05.04)
Final Efficacy and Safety Data From the Phase I/II ARROW Study of Pralsetinib in Patients With Advanced RET Fusion-Positive Non-Small Cell Lung Cancer. Besse B, Subbiah V, Curigliano G, Bowles DW, Doebele RC, Mansfield AS, Baik CS, de Lima Lopes G, Paz-Ares L, Taylor MH, Tan DSW, Alonso G, Gadgeel SM, Kalemkerian GP, Ou SI, van der Wekken AJ, Becerra CR, Evangelist M, Griesinger F, Liu SV, Lou Y, Mazières J, Melear JM, Narang M, Saxena A, Thomas M, Wang S, Thomassen A, Lee DH, Kim DW, Gainor JF. J Clin Oncol. 2026 Mar 26:JCO2501489. doi: 10.1200/JCO-25-01489. Epub ahead of print. PMID: 41886723.
Prediction of the individual risk for the development of brain metastases in patients with non-oncogene-addicted non-small cell lung cancer: Real-world data from the German prospective CRISP registry (AIO-TRK-0315). Acker F, Wenger K, Reck M, Waller CF, Hoffknecht P, Bethge A, Nusch A, Reiser M, Bernhardt C, Bendel M, Lennartz C, Fleitz A, Jänicke M, Ludwig P, Groth A, Griesinger F, Thomas M, Eberhardt WEE, Sebastian M; CRISP Registry Group. Int J Cancer. 2026 Mar 23. doi: 10.1002/ijc.70456. Epub ahead of print. PMID: 41872110.
Navigator-Based Slice Tracking for Multiband Accelerated Liver DWI. Zhang K, Triphan SMF, Fu C, Zhang N, Ziener CH, Ladd ME, Schlemmer HP, Kauczor HU, Sedlaczek O. Magn Reson Med. 2026 Mar 24. doi: 10.1002/mrm.70354. Epub ahead of print. PMID: 41873471.
The Implications of 9th Lung Cancer TNM Classification on Interventional Pulmonology. Brock JM, Gompelmann D. Respirology. 2026 Mar 24. doi: 10.1002/resp.70243. Epub ahead of print. PMID: 41876089.
Safety and feasibility of the Lung Volume Reduction Reverser (LVR-R) System in patients with severe emphysema - a first-in-human pilot study. Dittrich AS, Brock JM, Heussel CP, Herth FJF, Eberhardt R, Kontogianni K. Respiration. 2026 Mar 24:1-20. doi: 10.1159/000551022. Epub ahead of print. PMID: 41875298.
Real-World Treatment Patterns and Survival in Patients with ROS1-Positive Advanced Non-Small Cell Lung Cancer in Canada and Europe. Cheung WY, Lee A, Bote de Cabo H, Burdenski K, Christopoulos P, Pinto-Correia B, Deshayes S, Girard N, Hindocha P, Madden Á, Mella M, Moreira J, Rizzi S, Abreu DR, Soares M, Thomas J, Han M, Calvet CY, Emanuel G, Glassberg MB, Jacobs H, Rault C, Yuan Y, Chouaid C. Curr Oncol. 2026 Mar 6;33(3):152. doi: 10.3390/curroncol33030152. PMID: 41892180; PMCID: PMC13025971.
PVRI-GoDeep-A Global Meta-Registry at the Crossroads of Heart and Lung. Fuenderich MT, Yogeswaran A, Janetzko P, Tello K, Seeger W, Majeed RW, Wilhelm J; GoDeep Consortium. Compr Physiol. 2026 Apr;16(2):e70118. doi: 10.1002/cph4.70118. PMID: 41876955; PMCID: PMC13013090.
Defining quality standards of care in CTD-PAH and management best practices: a Delphi panel consensus. Del Galdo F, Coghlan JG, Gaine S, de Miguel IM, Smith V, Giuggioli D, Perry R, Grünig E. Rheumatol Adv Pract. 2026 Jan 14;10(2):rkag003. doi: 10.1093/rap/rkag003. PMID: 41878556; PMCID: PMC13006206.
68Gallium-labelled fibroblast activation protein inhibitor uptake in joints: a single-center cohort analysis of 268 patients. Spektor AM, van Genabith A, Hoppner J, Walkenbach L, Hielscher T, Kvacskay P, Richter S, Sungu-Winkler KT, Kauczor HU, Lorenz HM, Schreckenberger M, Distler J, Haberkorn U, Merkt W, Röhrich M. Eur J Nucl Med Mol Imaging. 2026 Apr;53(5):3226-3237. doi: 10.1007/s00259-025-07636-x. Epub 2025 Nov 20. PMID: 41261208; PMCID: PMC13013341.
Human airway organoids as a versatile model to study BSL-4 virus replication and pathogenesis. Wälzlein JH, Reusch S, Ospina-Garcia J, Olmer R, Schneider MA, Klotz LV, Klotz C, Kummer S. Sci Rep. 2026 Mar 27;16(1):10517. doi: 10.1038/s41598-026-45813-6. PMID: 41896609.
Assessment of pulmonary function in a mouse model of bronchopulmonary dysplasia by unrestrained whole-body plethysmography and the forced oscillation technique. Surate Solaligue DE, Nardiello C, Rodríguez-Castillo JA, Gunjak M, Lignelli E, Pérez Bravo D, Palumbo F, Mižik I, Pfeffer T, Myti D, Ruiz-Camp J, Steenbock H, Selvakumar B, Vadász I, Herold S, Genau S, Naehrlich L, Ehrhardt H, Hilgendorff A, Brinckmann J, Morse J, Robichaud A, Bates JHT, Seeger W, Morty RE. Am J Physiol Lung Cell Mol Physiol. 2026 Mar 26. doi: 10.1152/ajplung.00277.2025. Epub ahead of print. PMID: 41886515.
Association Between Subsegmental Dosing Accuracy and Outcomes of Bronchoscopic Thermal Vapor Ablation: An Exploratory Retrospective Study in Severe Heterogeneous Emphysema. Yang H, Chen S, Zheng X, Cui N, Xie F, Hou H, Ye L, Herth FJF, Sun J. Int J Chron Obstruct Pulmon Dis. 2026 Jan 23;21:560457. doi: 10.2147/COPD.S560457. PMID: 41878299; PMCID: PMC13006177.
S2k-Leitlinie Sicherheit der diagnostischen flexiblen Bronchoskopie bei Erwachsenender Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e. V. (DGP) [Safety of diagnostic flexible bronchoscopy in adults S2k-Guideline of the German Respiratory Society]. Hübner RH, Hetzel J, Baysal B †, Boeing S, Darwiche K, Eberhardt R, Eisenmann S, Franke KJ, Gesierich W, Gompelmann D, Heindl S, Herth F, Hetzel M, Holland A, Kahnert K, Loop T, Martiny H, Pizarro C, Quadder B, Richter T, Schmidt-Planck C, Stanzel F, Steinack C, Welcker K, Wustrack S, Hagmeyer L; Deutsche Gesellschaft für Pneumologie und Beatmungsmedizin e.V. (DGP) (federführende Fachgesellschaft); Deutsche Gesellschaft für Thoraxchirurgie e.V. (DGT); Deutsche Gesellschaft für Anästhesiologie und Intensivmedizin e.V. (DGAI); Deutsche Gesellschaft für Allgemeine und Krankenhaus-Hygiene e.V. (DGKH); Verband Pneumologischer Kliniken (VPK); Bundesverband der Pneumologie, Schlaf- und Beatmungsmedizin e.V. (BdP); Deutsche Gesellschaft für Endoskopiefachberufe e.V. (DEGEA); Österreichische Gesellschaft für Pneumologie (ÖGP); Schweizerische Gesellschaft für Pneumologie (SGP); Bundesverband Selbsthilfe Lungenkrebs e.V.; Deutsche Sarkoidose-Vereinigung gemeinnütziger e.V. (DSV); Deutsche Gesellschaft für Ultraschall in der Medizin – DEGUM e.V.; Deutsche Gesellschaft für Fachkrankenpflege und Funktionsdienste e. V. (DGF). Pneumologie. 2026 Mar 24. German. doi: 10.1055/a-2669-9409. Epub ahead of print. PMID: 41875917.
Woche 13 (23.03 - 29.03)
Diagnostic Value of EBUS-guided Transbronchial MEdiastinal Cryobiopsy versus ConvenTIONal Bronchoscopic Approaches for Intrathoracic Stage I/II SARcoidosis: protocol for a randomised controlled trial (DETECTION-SAR-II). Zheng Z, Wang H, Guo J, Zhang Q, Tang F, Xu L, Deng MM, Herth F, Poletti V, Hou G. BMJ Open Respir Res. 2026 Mar 19;13(1):e004065. doi: 10.1136/bmjresp-2025-004065. PMID: 41856756; PMCID: PMC13007058.
Value of Endobronchial Ultrasound-Derived Radiomics in Differentiating Pulmonary Sarcoidosis from Mediastinal Lymph Node Tuberculosis. Zhang Q, Zhao M, Wen F, Li X, Yang H, Liu H, Herth FJF, Hu W, Zhang X. Respiration. 2026 Mar 17:1-28. doi: 10.1159/000551556. Epub ahead of print. PMID: 41843711.
Woche 12 (16.03 - 22.03)
Impact of Combined Additional Resections on the Surgical Outcomes of Robot-Assisted Resection of Thymic Epithelial Tumors. Niedermaier B, Khan N, Eichhorn F, Zehentmeier M, Grosch H, Griffo R, Campisi A, Margineanu A, Allgäuer M, Christopoulos P, Thomas M, Winter H, Eichhorn ME. J Surg Oncol. 2026 Mar;133(3):382-388. doi: 10.1002/jso.70162. Epub 2025 Dec 18. PMID: 41410288; PMCID: PMC12989189.
Transthoracic robot-assisted minimally invasive diaphragmatic rupture repair: a case report. Griffo R, Campisi A, Deissner H, Niedermaier B, Reimer P, Winter H, Eichhorn ME. J Med Case Rep. 2026 Mar 15. doi: 10.1186/s13256-026-05944-w. Epub ahead of print. PMID: 41834048.
Long-Term Treatment with Single-Tablet Combination of Macitentan and Tadalafil in Pulmonary Arterial Hypertension: Results from A DUE and Its Open-Label Period. Ford HJ, Chin KM, Fan F, Friberg M, Grünig E, Hauser JA, Pannaux M, Rofael H, Jansa P. Adv Ther. 2026 Mar 12. doi: 10.1007/s12325-026-03525-3. Epub ahead of print. PMID: 41820779.
From hospital to home: Practical guidance when caring for patients with COPD and heart disease. Vogelmeier CF, Böhm M, Hurst JR, Kahnert K, Lange TJ, Taube C, Trinkmann F, Watz H, Rabe KF, Stolz D, Gediga M, Fabbri LM. Eur J Intern Med. 2026 Mar 8:106810. doi: 10.1016/j.ejim.2026.106810. Epub ahead of print. PMID: 41802970.
Sex differences in efficacy and adverse events following bronchoscopic thermal vapour ablation for severe emphysema: results from a multinational real-world registry. Trudzinski FC, Kontogianni K, Valipour A, Klemm T, Eisenmann S, Ficker J, Franzen D, Gesierich W, Grah C, Dittrich S, Höger P, Hammerl P, Hetzel M, Byczkowski T, Feisst M, Herth F, Darwiche K. BMJ Open Respir Res. 2026 Mar 11;13(1):e003932. doi: 10.1136/bmjresp-2025-003932. PMID: 41813031; PMCID: PMC12983785.
Gender, Medical Error, and the Culture of Scrutiny in Respiratory Medicine. Trudzinski FC, Herth F, Löffler-Ragg J, Janciauskiene S, Kahnert K, Oezkan F, Stolz D, Milger K. Respiration. 2026 Mar 9:1-4. doi: 10.1159/000550801. Epub ahead of print. PMID: 41802146.
Nachsorge von Erwachsenen nach Lungentransplantation [Follow-up care of adults after lung transplantation - an evidence based guideline]. Gottlieb J, Wald A, Bucher B, Tapp B, Hirsch C, Schneider C, Taube C, Winter H, Wilkens H, Geldmacher H, Hettich I, Jaksch P, Schuurmans M, Schiffer M, Hecker M, Nothacker M, Skoetz N, Kreuzberger N, Witzke O, Schmitt R, Jörger-Tuti S, Besa V, Veit W, Kneidinger N. Pneumologie. 2026 Mar 13. German. doi: 10.1055/a-2817-1499. Epub ahead of print. PMID: 41825464.
Versorgung bei unkontrolliertem Asthma in Deutschland [Care for uncontrolled asthma in Germany - with focus on Magdeburg and Mannheim regions]. Herth F, Schreiber J, Mokros I, Schwitalla JC, Vetter C. Dtsch Med Wochenschr. 2026 Mar 13. German. doi: 10.1055/a-2748-4843. Epub ahead of print. PMID: 41825462.
Endoscopic Ablation for Malignant Lung Lesions: Current Techniques, Unmet Needs, and Future Directions. Fernandez-Bussy S, Gutierrez-Gallegos P, Yu Lee-Mateus A, Brock JM, Quevedo-Salazar R, Abia-Trujillo D, Husta BC, Vu LH, Sun J, Herth F. Respiration. 2026;105(3):381-396. doi: 10.1159/000549189. Epub 2025 Oct 27. PMID: 41144620.
Bronchoscopic Lung Volume Reduction with Endobronchial Valves: A Consensus Statement on Practical Aspects of Patient Selection and Periprocedural Management. Wahidi MM, Lentz RJ, Criner GJ, Gompelmann D, Ing AJ, Kapp CM, Li S, Sciurba FC, Shah PL, Slebos DJ, Strange C, Herth FJ. Respiration. 2026;105(3):397-420. doi: 10.1159/000548437. Epub 2025 Sep 15. PMID: 40952939.
Woche 11 (09.03 - 15.03)
Correction: Diagnostic whole transcriptome sequencing in a series of 1233 FFPE solid tumor samples. Ball M, Beck S, Wlochowitz D, Fuchs T, Lorenz K, Zgorzelski C, Pallares Robles A, Allgäuer M, Volckmar AL, Goldschmid H, Ourailidis I, Brandt R, Christopoulos P, Thomas M, Seker-Cin H, Fink A, Schnecko F, Neumann O, Menzel M, Kirchner M, Fioretos T, Schirmacher P, Peters S, Budczies J, Stenzinger A, Kazdal D. Br J Cancer. 2026 Mar 2. doi: 10.1038/s41416-026-03360-x. Epub ahead of print. Erratum for: Br J Cancer. 2026 Jan 14. doi: 10.1038/s41416-025-03307-8. PMID: 41772276.
Analysis of body composition with bioelectrical impedance analysis in different subtypes of pulmonary fibrosis. Buschulte K, Ehrhart B, Kötter B, Dezfouli KA, Weinheimer O, Cremer K, Lederer C, Höger P, Polke M, Herth FFJ, Brock J. Sci Rep. 2026 Mar 6. doi: 10.1038/s41598-026-39350-5. Epub ahead of print. PMID: 41792240.
Reduced gastrointestinal iron uptake in pulmonary arterial hypertension: a prospective cross-sectional study. Repsold L, Harutyunova S, Grünig E, Benjamin N, Xanthouli P, Egenlauf B, Florea A, Shaukat M, Sparla R, Mertens C, Muckenthaler MU, Eichstaedt CA. Respir Res. 2026 Mar 2. doi: 10.1186/s12931-026-03592-8. Epub ahead of print. PMID: 41772585.
Significant Production of Serum and Mucosal Anti-Spike-IgA Antibodies After Vaccine-Encoded or SARS-CoV-2-Infection-Induced Spike-Exposures in Patients with Asthma Treated with Monoclonal Antibodies Compared to Conventional Therapy. Almanzar G, Broderdörp A, Mees J, Frey M, Herth FJF, Schneider MA, Trinkmann F, Prelog M. J Asthma Allergy. 2026 Feb 24;19:547038. doi: 10.2147/JAA.S547038. PMID: 41773183; PMCID: PMC12949803.
ESR Essentials: lung cancer screening with low-dose CT-practice recommendations by the European Society of Thoracic Imaging. Revel MP, Biederer J, Nair A, Silva M, Jacobs C, Snoeckx A, Prokop M, Prosch H, Parkar AP, Frauenfelder T, Larici AR. Eur Radiol. 2026 Mar;36(3):2064-2073. doi: 10.1007/s00330-025-11910-9. Epub 2025 Aug 23. PMID: 40848139; PMCID: PMC12963080.
Real-World Effectiveness and Safety of Single Inhaler Triple Therapy with Beclometasone/ Formoterol/ Glycopyrronium in Moderate to Severe Asthma: TriMaximize Study. Gessner C, Russell REK, Greulich T, Lommatzsch M, Suppli Ulrik C, Pohl W, Plaza V, Bourdin A, Kupczyk M, Braido F, Piraino A, Scaffidi-Argentina U, Bogoevska V, Trinkmann F; TriMaximize Core team; TriMaximize Core team; Akyildiz B, Fritz C, Grickschat V, Hahn A, Baumeister S, Richards J, Kisiel J, Krogh N. J Asthma Allergy. 2026 Feb 18;19:582286. doi: 10.2147/JAA.S582286. PMID: 41767174; PMCID: PMC12935525.
Woche 10 (02.03 - 08.03)
Systemic and Intracranial Efficacy and Safety of Trastuzumab Deruxtecan in Patients with HER2-Mutant Non-Small Cell Lung Cancer across Treatment Lines: Evidence from the TRACER/HERTras Real-World Cohort. Illini O, Hund AC, Kopp HG, Moskovitz M, Mountzios G, Brueckl WM, Früh M, Leßmann ME, Christopoulos P, Stenzinger A, Thomas M, Gillis R, Peled N, Acker F, Addeo A, Charpidou A, Grohé C, Mauti L, Rothschild SI, Schmid S, Schumann C, Urban D, Wurm R, Ekman S, Skribek M, Glanemann F, Wiesweg M, Ackermann CJ, Agelaki S, Hoffknecht P, Jakopović M, Kern J, König D, Kostenzer K, Kropf-Sanchen C, Laack E, Lang D, Nagl L, Pall G, Reck M, Kian W, Allemann AT, Alt J, Araújo D, Bokas A, Hannah F, Julie KJ, Weinlinger C, de Langen AJ, Fergadis EG, Fountzilas E, Froesch P, Frost N, Griesinger F, Jordan F, Karanikiotis C, Kiesewetter B, Korantzis I, Machado AL, Economopoulou P, Pilz A, Reimann P, Rittmeyer A, Saad A, Samitas K, Schulmann K, Shah R, Stratmann JA, Taghizadeh H, Tammoscheit K, Tufman A, Weber JP, Wöll E, Valipour A, Overbeck TR, Hochmair MJ. J Thorac Oncol. 2026 Feb 24:103651. doi: 10.1016/j.jtho.2026.103651. Epub ahead of print. PMID: 41747890.
Kongresse der deutschen und österreichischen Gesellschaft für Pneumologie 2025: Highlights aus dem Bereich der Interventionellen Pneumologie [DGP and ÖGP Congress 2025: Highlights from Interventional Pulmonology]. Limen E, Murauer G, Meilinger M, Hübner RH, Brock J, Gompelmann D. Pneumologie. 2026 Feb 24. German. doi: 10.1055/a-2790-3523. Epub ahead of print. PMID: 41734780.
Effectiveness of Lung Cancer Screening by Sex and Tumor Histology: Extended, Pooled Analysis of the ITALUNG and LUSI Trials, with Comparison to Findings in the NLST. Kaaks R, Cortés-Ibáñez FO, Delorme S, Motsch E, Katzke V, Heussel CP, Kauczor HU, Picozzi G, Gorini G, Carozzi FM, Carrozzi L, Paci E, Puliti D, Mascalchi M. Cancer Commun (Lond). 2026 Feb 24;46:0011. doi: 10.34133/cancomm.0011. PMID: 41743631; PMCID: PMC12929912.
Increase in second primary lung cancers in a nation-wide cohort study from Sweden. Zitricky F, Sundquist K, Sundquist J, Försti A, Hemminki A, Kaaks R, Hemminki K. Thorax. 2026 Feb 26:thorax-2025-223426. doi: 10.1136/thorax-2025-223426. Epub ahead of print. PMID: 41748422.
Sex Differences in Cancer Immunotherapy-Clinical Evidence and Mechanisms With a Focus on NSCLC. Krieghoff-Henning E, Pai B, Collienne M, Ben-Batalla I, Loges S. Immunol Rev. 2026 Mar;338(1):e70113. doi: 10.1111/imr.70113. PMID: 41761458; PMCID: PMC12949348.
Epigenetic dysregulation of IRF9 drives excessive interferon signaling in COPD. Llamazares-Prada M, Schwartz U, Pease DF, Pohl ST, Ackesson D, Li R, Behrendt A, Tamas R, Stammler V, Richter M, Muley T, Scherer M, Hey J, Espinet E, Heußel CP, Warth A, Schneider MA, Winter H, Herth FJ, Imbusch CD, Brors B, Benes V, Wyatt D, Jurkowski TP, Stahl HF, Plass C, Jurkowska RZ. EMBO Mol Med. 2026 Feb 23. doi: 10.1038/s44321-026-00386-9. Epub ahead of print. PMID: 41731077.
Onset and Development of Chronic Rhinosinusitis from Infancy through Adolescence in Primary Ciliary Dyskinesia Detected by Longitudinal Magnetic Resonance Imaging. Wucherpfennig L, Lulay M, Eichinger M, Seitz A, Schmitt N, Baumann I, Stahl M, Hämmerling S, Schenk JP, Alrajab A, Kauczor HU, Mall MA, Sommerburg O, Wielpütz MO. Ann Am Thorac Soc. 2026 Feb 25:aaoag045. doi: 10.1093/annalsats/aaoag045. Epub ahead of print. PMID: 41741347.
Clinical implications of a novel SERPINA1 variant c.236 T > A: Challenges in characterizing new rare alpha-1 antitrypsin mutations. Olivares-Rivera A, Ersöz H, Höger P, Veith M, Greulich T, Schlamp K, Janciauskiene S, Herth F, Trudzinski FC. Mol Genet Metab Rep. 2026 Feb 13;46:101295. doi: 10.1016/j.ymgmr.2026.101295. PMID: 41732190; PMCID: PMC12925186.
Comparison of 1.1-mm and 1.7-mm Probes in Transbronchial Mediastinal Cryobiopsy: A Randomized Trial. Zhong RH, Wu N, Li YD, Zhang J, Fu WL, Huang ZS, Zhang Y, Zhang SX, Jiang YQ, Yu YY, Kontogianni K, Herth FJF, Fan Y, Zhang Y.Arch Bronconeumol. 2026 Feb 24:S0300-2896(26)00043-8. English, Spanish. doi: 10.1016/j.arbres.2026.01.015. Epub ahead of print. PMID: 41741254.
Woche 9 (23.02 - 01.03)
World Expert Consensus Recommendations on Shape-Sensing Robotic-Assisted Bronchoscopy (ssRAB) for the Diagnosis of Peripheral Pulmonary Lesions. Brock JM, Fernandez-Bussy S, Yu Lee A, Chadha RM, Oberg C, Ng CSH, Chen E, Folch E, Zhang H, Reisenauer JS, Bhadra K, Pritchett MA, Shah PL, Li S, Patel P, Majid A, Herth FJF, Sun J. Respiration. 2026 Feb 16:1-41. doi: 10.1159/000551026. Epub ahead of print. PMID: 41697930.
Bridging the gap: A systematic approach to integrating serum and plasma proteomic datasets for biomarker studies. Lahav C, Dahan N, Harel M, Elon Y, Sela I, Geyer PE, Schneider MA, Muley T, Bacchiocchi A, Marte J, Floudas CS, Halaban R, Sznol M, Christopoulos P, Gulley JL. J Pharm Biomed Anal. 2026 Feb 14;274:117421. doi: 10.1016/j.jpba.2026.117421. Epub ahead of print. PMID: 41713118.
Bispecific T cell engagers for treatment-refractory autoimmune connective tissue diseases. Düsing C, Györfi AH, Stütz AN, Lahu LM, Deicher FS, Li YN, Bruch PM, Matei AE, Micu A, Filla T, Koziel S, Hölscher AS, Röhrich M, Lorenz HM, Cramer M, Antoch G, Timm J, Abusabha Y, Ruck T, Homey B, Kreuter A, Buehring B, Radujkovic A, Heußel CP, Hagen M, Grieshaber-Bouyer R, Schett G, Brunn A, Dietrich S, Merkt W, Distler JHW. Nat Med. 2026 Feb 19. doi: 10.1038/s41591-026-04238-4. Epub ahead of print. PMID: 41714747.
Transcriptomic signatures of IPF in ALI-cultured airway cells and their therapeutic implications. Chua RL, Veith C, Schneider MA, Jechow K, Kaufhold G, Alkildani S, Wild M, Sudy A, Xu EC, Kreuter M, Boots A, Eils R, Kahn NC, Conrad C. Thorax. 2026 Feb 18:thorax-2025-223325. doi: 10.1136/thorax-2025-223325. Epub ahead of print. PMID: 41713905.
Impact of TP53, KEAP1 and STK11 mutations in localized-stage NSCLC: A European thoracic oncology platform lungscape project. Molina-Vila MA, Tsourti Z, Vervita K, Bertran-Alamillo J, García-Peláez B, Kerr KM, Bubendorf L, Madsen LB, Biernat W, Stenzinger A, Haberecker M, Blackhall F, Pokharel S, Jordana-Ariza N, Vives-Usano M, Vagenknecht P, Dafni U, Kammler R, Finn SP, Peters S, Stahel RA, Rosell R.Eur J Cancer. 2026 Feb 17:116583. doi: 10.1016/j.ejca.2026.116583. Epub ahead of print. PMID: 41723072.
Evaluation of Vessel Enhancement Software for Improved Cerebrovascular Visualization in 3D Rotational Angiography. Schmitt N, Berting A, Wucherpfennig L, Preisner F, Mooshage CM, Hohenstatt S, Bendszus M, Möhlenbruch MA, Vollherbst DF. AJNR Am J Neuroradiol. 2026 Feb 19:ajnr.A9248. doi: 10.3174/ajnr.A9248. Epub ahead of print. PMID: 41714131.
Intercostal thickening fraction adds no value to diaphragm thickening fraction in healthy subjects undergoing noninvasive ventilation. Hoermann C, Drotleff LS, Link B, Doerflinger L, Neetz B, Michels-Zetsche JD, Herth FJF, Britsch M, Duerschmied D, Britsch S, Lindner S. Sci Rep. 2026 Feb 17;16(1):7165. doi: 10.1038/s41598-026-40192-4. PMID: 41703175; PMCID: PMC12920780.
Woche 8 (16.02 - 22.02)
Ultra-high-resolution synchrotron phase-contrast CT enables microstructural pulmonary imaging at clinical dose levels. Benke CV, Reiser J, D'Amico L, Sagar MMR, Sodini N, Dreossi D, Contillo A, Longo E, Prašek M, Stern S, Baratella E, Cova MA, Confalonieri M, Confalonieri P, Zanconati F, D'Errico S, Radaelli D, Bruscagin T, Bonazza D, Bayat S, Nolte P, Neubert L, Petzold-Mügge C, Werlein C, Knudsen L, Shin HO, Kamp JC, Hosseini ASA, Wagner WL, Wielpütz MO, Biederer J, Kauczor HU, Alves F, Tromba G, Dullin C. Respir Res. 2026 Feb 11. doi: 10.1186/s12931-026-03561-1. Epub ahead of print. PMID: 41673865.
Woche 7 (09.02 - 15.02)
Institutional variability in testing for actionable genetic alterations in patients with stage IIIB/C or IV non-small cell lung cancer: A real-world study from the German prospective, observational, multicenter CRISP registry (AIO-TRK-0315). Althoff FC, Hummel HD, Kokowski K, Elender C, Grah C, Zacharias S, Fleitz A, Jänicke M, Groth A, Ludwig P, Nusch A, Reiser M, Pelz H, Wiegand J, Griesinger F, Thomas M, Eberhardt WEE, Sebastian M; CRISP Registry Group. Eur J Cancer. 2026 Jan 30;236:116265. doi: 10.1016/j.ejca.2026.116265. Epub ahead of print. PMID: 41633313.
Advancing Lung Cancer Staging: Integrating IASLC Recommendations and Bioinformatics to Delineate Tumor Origins. Allgäuer M, Kluck K, Christopoulos P, Ball M, Volckmar AL, Radonic T, Bubendorf L, Hofman P, Heußel CP, Winter H, Herth F, Thomas M, Ylstra B, Peters S, Schirmacher P, Kazdal D, Budczies J, Stenzinger A, Kirchner M. J Thorac Oncol. 2026 Feb;21(2):267-282. doi: 10.1016/j.jtho.2025.10.010. Epub 2025 Oct 22. PMID: 41135642.
The role of zongertinib, a highly selective tyrosine kinase inhibitor, in targeting HER2-mutant NSCLC: a bench-to-bedside review. Heymach JV, Popat S, Smit EF, Christopoulos P, Planchard D, Yoshida T, Zugazagoitia J, Yu Y, Wilding B. Expert Rev Anticancer Ther. 2026 Feb 4. doi: 10.1080/14737140.2026.2623059. Epub ahead of print. PMID: 41640088.
Digital Biopsy and Network Analysis of Dynamic [68Ga]Ga-FAPI-46 Data in Patients with Malignant and Benign Pancreatic Lesions. Röhrich M, Glatting FM, Geisinger M, Spektor AM, Buchholz HG, Wessendorf J, von Goetze I, Hoppner J, Liermann J, Knoll M, Lang M, Heger U, Schreckenberger M, Loos M, Tavares A, Herfarth K, Debus J, Haberkorn U, Macaskill MG. J Nucl Med. 2026 Feb 2;67(2):304-312. doi: 10.2967/jnumed.125.270185. PMID: 41266254; PMCID: PMC12866391.
Exciting times for trimodulin. Morty RE. Eur Respir J. 2026 Feb 5;67(2):2502297. doi: 10.1183/13993003.02297-2025. PMID: 41644176.
Exploring the effects of tinzaparin and cisplatin on lung cancer cells in vitro. Held J, Schneider MA, Martinez-Delgado B, Liu B, DeLuca DS, Korenbaum E, Janciauskiene S, Muley T. Cancer Cell Int. 2026 Feb 5. doi: 10.1186/s12935-026-04214-5. Epub ahead of print. PMID: 41645201.
Woche 6 (02.02 - 08.02)
Heritable pulmonary arterial hypertension: new genetic findings and environmental triggers. Shaukat M, Grünig E, Haas S, Haas J, Panahi M, Granzow M, Lange TJ, Stadler S, Sommer N, Dorfmüller P, Meder B, Harutyunova S, Egenlauf B, Xanthouli P, Hinderhofer K, Eichstaedt CA. Sci Rep. 2026 Jan 29;16(1):4121. doi: 10.1038/s41598-025-34167-0. PMID: 41611798; PMCID: PMC12858969.
Predicting exercise pulmonary hypertension: the right-net machine learning model a pilot study. Ferrara F, Castaldo R, Gargani L, Benjamin N, Carbone A, Carluccio E, Cittadini A, Codullo V, D'Agostino A, D'Alto M, Grünig E, Esposito AM, Esposito G, Ghio S, Kasprzak JD, Lacava G, Marra AM, Matucci-Cerinic M, Moreo A, Picano E, Rega S, Soricelli A, Wierzbowska-Drabik K, Naeije R, Bossone E, Franzese M. Transl Res. 2026 Jan;287:12-21. doi: 10.1016/j.trsl.2025.12.007. Epub 2025 Dec 30. PMID: 41478527.
A Systematic Review of the Safety of Sedation during Flexible Bronchoscopy. Matthes S, Treml M, Hübner RH, Hetzel J, Eberhardt R, Franke KJ, Herth FJ, Holland A, Loop T, Sitter H, Randerath WJ, Hagmeyer L. Respiration. 2026;105(1):37-56. doi: 10.1159/000548435. Epub 2025 Sep 16. PMID: 40956775.
Revisiting Lymph Node Staging in the 9th TNM Classification for Lung Cancer: A Bronchoscopic Perspective. Brock JM, Herth FJF. Respiration. 2026;105(1):57-67. doi: 10.1159/000548344. Epub 2025 Sep 5. PMID: 40911516.
Flexible bronchoscopy-assisted removal of aspirated scarf pins from the tracheobronchial tree: the experience of 146 subjects. Hussein SA, Gonuguntla HK, Tahura S, Preeti B, Krishnan VG, Gupta N, Al-Halfawy A, Herth FJ. Monaldi Arch Chest Dis. 2025 Dec 31;95(4). doi: 10.4081/monaldi.2024.3193. Epub 2024 Oct 25. PMID: 39470224.
Woche 5 (26.01 - 01.02)
Rising incidence of carbapenem-resistant Citrobacter spp. in a German tertiary-care hospital: epidemiology, clinical impact, and the role of the hospital wastewater system-findings from a six-year molecular study. Tsakmaklis H, Weidner NM, Kocer K, Behnisch R, Jäger D, Michl P, Mieth M, Busch E, Brandt C, Dalpke AH, Nurjadi D, Boutin S, Späth I. Microbiol Spectr. 2026 Jan 22:e0267025. doi: 10.1128/spectrum.02670-25. Epub ahead of print. PMID: 41568952.
Endobronchial ultrasound-guided mediastinal biopsies for the diagnosis of mediastinal diseases: A network meta-analysis. Qi YJ, Zhang J, Salcedo Lobera E, Song QY, Zhong RH, Kontogianni K, Huang ZS, Ariza-Prota M, Gupta N, Madan M, Maturu VN, Pratibh Prasad V, Steinack C, Wu N, Gaisl T, Herth FJ, Fan Y. Pulmonology. 2026 Dec;32(1):2593067. doi: 10.1080/25310429.2025.2593067. Epub 2026 Jan 20. PMID: 41560513.
Prevention, diagnosis and management of community acquired respiratory virus infections including COVID-19 in patients with cancer: 2025 updated evidence-based guideline of the infectious diseases working party (AGIHO) of the German society for hematology and medical oncology (DGHO). Giesen N, Mellinghoff SC, Khatamzas E, Korell F, Hentrich M, Einsele H, Henze L, Heußel CP, Hohmann C, Jensen BO, Monin MB, Schafhausen P, Schalk E, Spiekermann K, Voigt S, von Lilienfeld-Toal M, Teschner D, Cornely OA, Rieger C, Busch E. Ann Hematol. 2026 Jan 21;105(2):46. doi: 10.1007/s00277-026-06769-9. PMID: 41563477; PMCID: PMC12823726.
Genetic contribution to severe COVID-19 in adults under 60 years without major comorbidities in the German National Pandemic Cohort Network (NAPKON). Abolhassani A, Alawathurage TM, Schmidt A, Brand F, Kilarski LL, Altmann H, Dahl E, Frank S, Göpel S, Hanses F, Hellmuth JC, Herr C, Kaasch AJ, Kobbe R, Konik MJ, Pink I, Römmele C, Rupp J, Scheer CS, Schneider MA, Stellbrink C, Stubbe HC, Tepasse PR, Teufel A, Vadász I, Vehreschild MJGT, Witzenrath M, Anton G, Bröhl I, Herold S, Illig T, Jiru-Hillmann S, Krawitz P, Mitrov L, Philipsen A, Pütz SM, Noethen MM, Nuernberg P, Reese JP, Riess O, Schreiber S, Schultze J, Steinbeis F, Vehreschild JJ, Wildberg C, Ludwig KU, Schulte EC. Hum Genomics. 2026 Jan 23;20(1):23. doi: 10.1186/s40246-025-00904-9. PMID: 41578410; PMCID: PMC12849158.
Woche 4 (19.01 - 25.01)
Diagnostic whole transcriptome sequencing in a series of 1233 FFPE solid tumor samples. Ball M, Beck S, Wlochowitz D, Fuchs T, Lorenz K, Zgorzelski C, Pallares Robles A, Allgäuer M, Volckmar AL, Goldschmid H, Ourailidis I, Brandt R, Christopoulos P, Thomas M, Seker-Cin H, Fink A, Schnecko F, Neuman O, Menzel M, Kirchner M, Fioretos T, Schirmacher P, Peters S, Budczies J, Stenzinger A, Kazdal D. Br J Cancer. 2026 Jan 14. doi: 10.1038/s41416-025-03307-8. Epub ahead of print. PMID: 41530577.
PD1 blockade-induced DKK1 expression by CD8+ T cells promotes blood-brain barrier permeabilization. Deo A, Levin S, Buxbaum C, Benguigui M, Manobla B, Saar G, Bosak N, Bergmann E, Eran A, Grinfeld A, Harel M, Lahav C, Raviv Z, Daher S, Zer A, Reuter JH, Heuβel CP, Christopoulos P, Yizhak K, Shaked Y. Cancer Discov. 2026 Jan 13. doi: 10.1158/2159-8290.CD-25-1222. Epub ahead of print. PMID: 41525686.
Male survival disadvantage in pulmonary hypertension: independent of aetiology, age, disease severity, comorbidities and treatment. Yogeswaran A, Annis JS, Fünderich M, Wilhelm J, Kiely DG, Howard L, Lawrie A, Wilkins MR, Balasubramanian A, Hassoun PM, Konswa Z, Eichstaedt CA, Grünig E, Sweatt AJ, Zamanian RT, Kovacs G, Olschewski H, Lichtblau M, Ulrich S, Thenappan T, Al Ghouleh I, Chan SY, Elwing J, Jose A, Cannon J, Pepke-Zaba J, Frantz R, Sirenko Y, Torbas O, Sahay S, Zhai Z, Zhang Z, Arvanitaki A, Giannakoulas G, Frauendorf M, Williams PG, Kuronuma K, Matsubara H, Ghio S, Scelsi L, Sabbour H, Saleh K, Anthi A, Dima E, Majeed RW, Ghofrani HA, Grimminger F, Tello K, Cajigas HR, Brittain E, Seeger W; PVRI Consortium. EBioMedicine. 2026 Jan;123:106063. doi: 10.1016/j.ebiom.2025.106063. Epub 2025 Dec 16. PMID: 41406504; PMCID: PMC12768861.
Woche 3 (12.01 - 18.01)
Trachealtumoren [Tracheal Tumours]. Eichhorn F, Hoffmann H, Rieken S, Herth FJF, Winter H. Laryngorhinootologie. 2026 Jan;105(1):13-24. German. doi: 10.1055/a-2657-8626. Epub 2025 Aug 5. PMID: 40763766.
Advances in orphan drug development for alpha-1 antitrypsin deficiency: a 2025 update from the FDA and EMA. Höger P, Ries M, Olivares Rivera A, Ersöz H, Buschulte K, Fähndrich S, Kontogianni K, Herth F, Trudzinski FC. Ther Adv Respir Dis. 2026 Jan-Dec;20:17534666251411227. doi: 10.1177/17534666251411227. Epub 2026 Jan 7. PMID: 41499187; PMCID: PMC12779913.
Hitting the Bull's AI: Artificial Intelligence-derived Imaging Features and their Association with Outcomes in CT-guided Lung Biopsy, a Retrospective Study. Roller C, Ittermann T, Syperek A, Mühler M, Wielpütz MO, Kühn JP, Blum SF, Schön F, Winter P, Schnell S, Kromrey ML. Eur J Radiol. 2025 Dec 31;195:112642. doi: 10.1016/j.ejrad.2025.112642. Epub ahead of print. PMID: 41519025.
Less Is More? Minimizing Overtreatment in Patients With Multifocal Ground-Glass Opacities. Niedermaier B, Winter H. J Thorac Oncol. 2026 Jan;21(1):26-28. doi: 10.1016/j.jtho.2025.09.1758. PMID: 41519533.
Woche 2 (05.01 - 11.01)
Predicting Exercise Pulmonary Hypertension: The RIGHT-NET Machine Learning model A Pilot Study. Ferrara F, Castaldo R, Gargani L, Benjamin N, Carbone A, Carluccio E, Cittadini A, Codullo V, D'Agostino A, D'Alto M, Grünig E, Esposito AM, Esposito G, Ghio S, Kasprzak JD, Lacava G, Marra AM, Matucci-Cerinic M, Moreo A, Picano E, Rega S, Soricelli A, Wierzbowska-Drabik K, Naeije R, Bossone E, Franzese M. Transl Res. 2025 Dec 30:S1931-5244(25)00121-5. doi: 10.1016/j.trsl.2025.12.007. Epub ahead of print. PMID: 41478527.
Association of Obesity with Symptoms and Quality of Life in COPD: Results from COSYCONET. Alter P, Watz H, Machado FVC, Speicher T, Trudzinski FC, Kahnert K, Bals R, Wouters EFM, Franssen FME, Vogelmeier CF, Karrasch S, Jörres RA. Int J Chron Obstruct Pulmon Dis. 2025 Dec 25;20:4129-4141. doi: 10.2147/COPD.S542628. PMID: 41476636; PMCID: PMC12747889.
Clinical application of HEDI for biomechanical evaluation and visualisation in incisional hernia repair. Lösel PD, Relle JJ, Voß S, Raschidi R, Nessel R, Görich J, Wielpütz MO, Löffler T, Heuveline V, Kallinowski F. Commun Med (Lond). 2026 Jan 4. doi: 10.1038/s43856-025-01311-w. Epub ahead of print. PMID: 41484463.
Woche 1 (29.12 - 04.01)
SputOMICs identifies common and distinct markers in cystic fibrosis and chronic obstructive pulmonary disease. Frey DL, Helm B, Guerra M, Hagner M, Lu J, Dittrich AS, Wege S, Eberhardt R, Herth FJF, Sommerburg O, Schultz C, Dalpke AH, Klingmüller U, Mall MA, Boutin S. Sci Rep. 2025 Dec 24;15(1):44418. doi: 10.1038/s41598-025-32565-y. PMID: 41436524; PMCID: PMC12738762.
Evaluation of Projection Images for Visual Quality Control of Automated Left and Right Lung Segmentations on T1-Weighted MRI in Large-Scale Clinical Cohort Studies. Norajitra T, Schlett CL, von Krüchten R, Agarwal P, Ravindran A, Do TD, Kausch L, Karrasch S, Kauczor HU, Maier-Hein K, Melzig C. Tomography. 2025 Nov 29;11(12):135. doi: 10.3390/tomography11120135. PMID: 41441387; PMCID: PMC12736869.
