Prof. Dr. med.
Mark Oliver Wielpütz

Education and Training

Professor Mark O. Wielpütz is Principal Investigator at the Translational Lung Research Center Heidelberg (TLRC) and from 2012-2020 he was Head of the Junior Research Group "Structural and Functional Airway Imaging". In 2016 he became the Head of the Section Pulmonary Imaging at Heidelberg University Hospital. After completing his studies of human medicine at the University of Erlangen-Nuremberg, he received his doctorade and worked as a junior fellow at the Department of Diagnostic and Interventional Radiology and as a research assistant at the DKFZ from 2009. He habilitated in radiology in 2016. In 2019, he has been appointed Associate Professor and also received a Masters Degree in Health Business Administration (MHBA).

Expertise

The aim of the doctors and scientists of his group is to investigate the mechanisms of development of common congenital or acquired chronic lung diseases such as cystic fibrosis (CF), COPD or pulmonary malignancy such as lung cancer.

The Junior Research Group "Structural and Functional Airway Imaing" is primarily concerned with the research of functional CT and MRI techniques in patients with chronic obstructive airway diseases such as cystic fibrosis.

Prizes and Awards

For his work on MRI of cystic fibrosis, Prof. Wielpütz received the Christiane Herzog Research Award from the Christiane Herzog Foundation and Mukovsizidose e.V., one of the highest endowed prizes for young researchers with € 50,000.

• Functional pulmonary imaging
• Muco-obstructive lung disease
• Cystic fibrosis

• Chronic Obstructive Pulmonary Disease
• Cystic Fibrosis
• Platform Imaging

1. Wielpütz MO, Puderbach M, Kopp-Schneider A, Stahl M, Fritzsching E, Sommerburg O, Sumkauskaite M, Ley S, Biederer J, Kauczor HU, Eichinger M, Mall MA. Magnetic resonance imaging detects changes in structure and perfusion, and response to therapy in early cystic fibrosis lung disease. Am J Respir Crit Care Med, 2014; 189(8):956-65

2. Stahl M*, Wielpütz MO*, Graeber SY, Joachim C, Sommerburg O, Kauczor HU, Puderbach M, Eichinger M, Mall MA (* geteilte Erstautorenschaft). Comparison of lung clearance index and magnetic resonance imaging for assessment of lung disease in children with cystic fibrosis. Am J Respir Crit Care Med, 2017; 195(3):349-359

3. Wielpütz MO, Eichinger M, Wege S, Eberhardt R, Mall MA, Kauczor HU, Puderbach MU, Risse F, Heußel CP, Heußel G. Mid-term reproducibility of chest MRI in adults with clinically stable cystic fibrosis and chronic obstructive pulmonary disease. Am J Respir Crit Care Med, 2019; 200(1):103-107

4. Schiwek M, Triphan SMF, Biederer J, Weinheimer O, Eichinger M, Vogelmeier CF, Jörres RA, Kauczor HU, Heußel CP, Konietzke P, von Stackelberg O, Risse F, Jobst BJ, Wielpütz MO. Quantification of pulmonary perfusion abnormalities on contrast-enhanced MRI in COPD: Comparison with quantitative computed tomography and pulmonary function. Eur Radiol, 2021; online first

5. Stahl M, Steinke E, Graeber SY, Joachim C, Seitz C, Kauczor HU, Eichinger M, Hämmerling S, Sommerburg O, Wielpütz MO*, Mall MA* (*geteilte Letztautorenschaft). MRI detects progression of lung disease and impact of NBS in preschool children with CF. Am J Respir Crit Care Med, 2021; online first

PubMed Link