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Prof. Dr. med., Thomas Kuner

Director Department of Functional Neuroanatomy

Heidelberg University

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Studies of Medicine at Heidelberg Universität, doctoral thesis (“summa cum laude”) with Prof. Dr. Peter Seeburg at the Center for Molecular Biology Heidelberg, postdoctoral fellow with Prof. George Augustine at Duke University Medical Center in Durham (USA), group leader at the department of Cell Physiology with Prof. Dr. Bert Sakmann, Max-Planck-Institute for Medical Research Heidelberg, Habilitation in physiology. Since 2006 professor at the Institute for Anatomie und Zellbiologie, since 2012 director oft the Department of Functional Neuroanatom.

  • Translational lung research, electron microscopy of the lung
  • Development and application of new microscopy techniques in super-resolution- and electron microscopy

Cystic fibrosis (CF)

  1. Wagner, W.L., Zheng, Y., Pierce, A., Ackermann, M., Horstmann, H., Kuner, T., Ronchi, P., Schwab, Y., Konietzke, P., Wünnemann, F., et al. Mesopolysaccharides: The extracellular surface layer of visceral organs. PloS One, 2019; 15, e0238798.

  2. Klevanski, M., Herrmannsdörfer, F., Sass, S., Venkataramani, V., Heilemann, M. Kuner, T. Automated highly multiplexed super-resolution imaging of protein nano-architecture in cells and tissues. Nature Communications, 2020; 11:1552.

  3. Venkataramani, V., Herrmannsdörfer, F., Heilemann, M., Kuner, T. SuReSim – Simulating localization microscopy experiments from ground truth models. Nature Methods, 2016; 13:319-21.

  4. Horstmann, H., Vasileva, M., & Kuner, T. Photooxidation-Guided Ultrastructural Identification and Analysis of Cells in Neuronal Tissue Labeled with Green Fluorescent Protein. PloS One, 2013; 8(5), e64764.

  5. Horstmann, H., Körber, C., Sätzler, K., Aydin, D., Kuner, T. Serial Section Scanning Electron Microscopy (S3EM) on Silicon Wafers for Ultrastructural Volume Imaging of Cells and Tissues. PLoS One 2012; 7(4): e35172.

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Yvette Dörflinger

Electron microscopy specialist

 

Simone Hoppe

Electron microscopy specialist

 

Dr. Maja Klevanski

Postdoctoral Fellow

 

Dr. Willi Wagner (DIR)

Resident physician

 

Lung Research Projects

  1. Ultrastructure of mucus plugging in cystic fibrosis
  2. Mesothelial glycocalyx and interaction with pectin biopolymers
  3. Resin-free electron microscopy of lung tissue
  4. Correlative micro-CT and electron microscopic imaging across scales