Publications

New this week in PubMed
from TLRC Faculty

New this week - TLRC Faculty 2023

Week 51 (18.23 - 24.12)

Pulsed stimulated Brillouin microscopy enables high-sensitivity mechanical imaging of live and fragile biological specimens. Yang F, Bevilacqua C, Hambura S, Neves A, Gopalan A, Watanabe K, Govendir M, Bernabeu M, Ellenberg J, Diz-Muñoz A, Köhler S, Rapti G, Jechlinger M, Prevedel R. Nat Methods. 2023 Dec;20(12):1971-1979. doi: 10.1038/s41592-023-02054-z. Epub 2023 Oct 26.

Characteristics of Current Smokers versus Former Smokers with COPD and Their Associations with Smoking Cessation Within 4.5 Years: Results from COSYCONET. Alter P, Stoleriu C, Kahnert K, Henke MO, Bals R, Trudzinski FC, Watz H, Speicher T, Söhler S, Welte T, Rabe KF, Wouters EFM, Vogelmeier CF, Jörres RA. Int J Chron Obstruct Pulmon Dis. 2023 Dec 6;18:2911-2923. doi: 10.2147/COPD.S436669.

High-resolution CT phenotypes in pulmonary sarcoidosis: a multinational Delphi consensus study. Desai SR, Sivarasan N, Johannson KA, George PM, Culver DA, Devaraj A, Lynch DA, Milne D, Renzoni E, Nunes H, Sverzellati N, Spagnolo P, Baughman RP, Yadav R, Piciucchi S, Walsh SLF, Kouranos V, Wells AU; Sarcoid Delphi Group. Lancet Respir Med. 2023 Dec 14:S2213-2600(23)00267-9. doi: 10.1016/S2213-2600(23)00267-9.

Outcome after cytoreductive surgery combined with hyperthermic intrathoracic chemotherapy in patients with secondary pleural metastases. Hassan M, Zimmermann J, Schmid S, Passlick B, Kovács J, Hatz R, Winter H, Klotz LV, Eichhorn ME, Markowiak T, Müller K, Huppertz G, Koller M, Hofmann HS, Ried M. Front Oncol. 2023 Nov 28;13:1259779. doi: 10.3389/fonc.2023.1259779.

Outcome of first-line treatment with pembrolizumab according to KRAS/TP53 mutational status for non-squamous PD-L1 high (≥50%) NSCLC in the German National Network Genomic Medicine Lung Cancer (nNGM). Bischoff P, Reck M, Overbeck T, Christopoulos P, Rittmeyer A, Lüders H, Kollmeier J, Kulhavy J, Kemper M, Reinmuth N, Röper J, Janning M, Sommer L, Aguinarte L, Koch M, Wiesweg M, Wesseler C, Waller CF, Kauffmann-Guerrero D, Stenzinger A, Stephan-Falkenau S, Trautmann M, Lassmann S, Tiemann M, Klauschen F, Sebastian M, Griesinger F, Wolf J, Loges S, Frost N; National Network Genomic Medicine Lung Cancer (nNGM) collaborator group. J Thorac Oncol. 2023 Dec 12:S1556-0864(23)02423-1. doi: 10.1016/j.jtho.2023.12.015.

Simultaneous T₁, T₂ and T₂^⁎ mapping of the liver with multi-shot MI-SAGE. Zhang K, Triphan SMF, Wielpütz MO, Ziener CH, Ladd ME, Schlemmer HP, Kauczor HU, Kurz FT, Sedlaczek O. Magn Reson Imaging. 2024 Jan;105:75-81. doi: 10.1016/j.mri.2023.11.004.

Week 50 (11.12 - 17.12)

First experience with real-time magnetic resonance imaging-based investigation of respiratory influence on cardiac function in pediatric congenital heart disease patients with chronic right ventricular volume overload. Röwer LM, Radke KL, Hußmann J, Malik H, Eichinger M, Voit D, Wielpütz MO, Frahm J, Klee D, Pillekamp F. Pediatr Radiol. 2023 Dec;53(13):2608-2621. doi: 10.1007/s00247-023-05765-9.

Oral Treprostinil is Associated with Improved Survival in FREEDOM-EV and its Open-Label Extension. Grünig E, Rahaghi F, Elwing J, Vizza CD, Pepke-Zaba J, Shen J, Yao H, Hage A, Rosenkranz S, Vonk M, Balasubramanian V, Yuanhua Y, Yu Z, Lordan J, Cadaret L, Grover R, Ousmanou A, Seaman S, Deng C, Broderick M, White RJ; FREEDOM-EV Investigators. Adv Ther. 2023 Dec 6. doi: 10.1007/s12325-023-02711-x.

The Theranostic Optimization of PSMA-GCK01 Does Not Compromise the Imaging Characteristics of [^99mTc]Tc-PSMA-GCK01 Compared to Dedicated Diagnostic [^99mTc]Tc-EDDA/HYNIC-iPSMA in Prostate Cancer. Mamlins E, Scharbert L, Cardinale J, Krotov M, Winter E, Rathke H, Strodel B, Ankrah AO, Sathekge M, Haberkorn U, Kratochwil C, Giesel FL. Mol Imaging Biol. 2023 Dec 8. doi: 10.1007/s11307-023-01881-y.

Willingness to participate in combination screening for lung cancer, chronic obstructive pulmonary disease and cardiovascular disease in four European countries. Behr C, Koffijberg H, IJzerman M, Kauczor HU, Revel MP, Silva M, von Stackelberg O, van Til J, Vliegenthart R. Eur Radiol. 2023 Dec 7. doi: 10.1007/s00330-023-10474-w.

Week 48 (27.11 - 3.12)

Acute expression of human APOBEC3B in mice results in RNA editing and lethality. Alonso de la Vega A, Temiz NA, Tasakis R, Somogyi K, Salgueiro L, Zimmer E, Ramos M, Diaz-Jimenez A, Chocarro S, Fernández-Vaquero M, Stefanovska B, Reuveni E, Ben-David U, Stenzinger A, Poth T, Heikenwälder M, Papavasiliou N, Harris RS, Sotillo R. Genome Biol. 2023 Nov 24;24(1):267. doi: 10.1186/s13059-023-03115-4.

Amivantamab Compared with Real-World Physician's Choice after Platinum-Based Therapy from a Pan-European Chart Review of Patients with Lung Cancer and Activating EGFR Exon 20 Insertion Mutations. Christopoulos P, Girard N, Proto C, Soares M, Lopez PG, van der Wekken AJ, Popat S, Diels J, Schioppa CA, Sermon J, Rahhali N, Pick-Lauer C, Adamczyk A, Penton J, Wislez M. Cancers (Basel). 2023 Nov 8;15(22):5326. doi: 10.3390/cancers15225326.

Causes and Risk Factors for Absenteeism among Medical Staff in German Specialized Lung Clinics during the COVID Pandemic. Piel S, Presotto MA, Jörres RA, Karrasch S, Gesierich W, Bullwinkel J, Rabe KF, Hayden MC, Kaestner F, Harzheim D, Joves B, Kempa AT, Ghiani A, Neurohr C, Michels JD, Kreuter M, Herth FJF, Trudzinski FC. Respiration. 2023;102(11):924-933. doi: 10.1159/000534327

Week 47 (20.11 - 26.11)

Exercise Stress Echocardiography of the Right Ventricle and Pulmonary Circulation. Gargani L, Pugliese NR, De Biase N, Mazzola M, Agoston G, Arcopinto M, Argiento P, Armstrong WF, Bandera F, Cademartiri F, Carbone A, Castaldo R, Citro R, Cocchia R, Codullo V, D'Alto M, D'Andrea A, Douschan P, Fabiani I, Ferrara F, Franzese M, Frumento P, Ghio S, Grünig E, Guazzi M, Kasprzak JD, Kolias T, Kovacs G, La Gerche A, Limogelli G, Marra AM, Matucci-Cerinic M, Mauro C, Moreo A, Pratali L, Ranieri B, Rega S, Rudski L, Saggar R, Salzano A, Serra W, Stanziola AA, Vannan MA, Voilliot D, Vriz O, Wierzbowska-Drabik K, Cittadini A, Naeije R, Bossone E; RIGHT Heart International NETwork (RIGHT-NET) Investigators. J Am Coll Cardiol. 2023 Nov 21;82(21):1973-1985. doi: 10.1016/j.jacc.2023.09.807.

[General measures and management of pulmonary arterial hypertension]. Lichtblau M, Harutyunova S, Nechwatal R, Mayer L, Kabitz HJ, Wilkens FM, Uiker S, Grünig E, Ritter D, Florea A, Benjamin N. Pneumologie. 2023 Nov;77(11):907-915. doi: 10.1055/a-2145-4741. Epub 2023 Nov 14.

[Genetic diagnostics and molecular approaches in pulmonary arterial hypertension]. Eichstaedt CA, Bikou O, Sommer N, Schermuly RT, Pullamsetti SS, Weissmann N, Harbaum L, Tabeling C, Wißmüller M, Foris V, Kuebler WM, Hinderhofer K, Olschewski A, Kwapiszewska G. Pneumologie. 2023 Nov;77(11):862-870. doi: 10.1055/a-2145-4663. Epub 2023 Nov 14.

[Medication treatment in pulmonary arterial hypertension with comorbidities - Which phenotypes and points to consider]. Grünig E, Halank M, Neurohr C, Behr J, Milger-Kneidinger K, Ronczka J, Lichtblau M, Benjamin N, Lange TJ, Ulrich S, Wilkens H, Grohé C, Skowasch D. Pneumologie. 2023 Nov;77(11):901-906. doi: 10.1055/a-2145-4726. Epub 2023 Nov 14.

[New definition and classification of pulmonary hypertension]. Douschan P, Egenlauf B, Gall H, Grünig E, Hager A, Heberling M, Koehler T, Olschewski H, Seyfarth HJ, Yogeswaran A, Ulrich S, Kovacs G. Pneumologie. 2023 Nov;77(11):854-861. doi: 10.1055/a-2145-4648. Epub 2023 Nov 14.

[Pulmonary arterial hypertension in congenital heart disease - Part I]. Kaemmerer H, Diller GP, Dähnert I, Eichstaedt CA, Eicken A, Freiberger A, Freilinger S, Geiger R, Gorenflo M, Grünig E, Hager A, Herberg U, Huntgeburth M, Kaemmerer AS, Kozlik-Feldmann R, Lammers A, Nagdyman N, Michel S, Schmidt KH, Uebing A, von Scheidt F, Apitz C. Pneumologie. 2023 Nov;77(11):956-961. doi: 10.1055/a-2146-7434. Epub 2023 Nov 14.

[The new European Guidelines for Pulmonary Hypertension with Updated Commentary of the PH-DACH Conference - A position paper of the German Society for Pneumology and Respiratory Medicine (DGP)]. Grünig E, Benjamin N, Behr J, Skowasch D, Milger-Kneidinger K, Halank M, Kuebler WM, Kovacs G, Lichtblau M, Guth S, Apitz C, Kaemmerer H, Tello K, Ulrich S; unter der Schirmherrschaft der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin (DGP e. V.). Pneumologie. 2023 Nov;77(11):852-853. doi: 10.1055/a-2146-7472. Epub 2023 Nov 14.

Week 46 (13.11 - 19.11)

Clinical factors linked to the type of respiratory medication in COPD: results from the COSYCONET cohort. Alter P, Kahnert K, Trudzinski FC, Bals R, Watz H, Speicher T, Söhler S, Welte T, Rabe KF, Wouters EFM, Vogelmeier CF, Jörres RA. Ther Adv Respir Dis. 2023 Jan-Dec;17:17534666231208584. doi: 10.1177/17534666231208584.

Pulmonary fibrosis: from pathogenesis to clinical decision-making. Koudstaal T, Funke-Chambour M, Kreuter M, Molyneaux PL, Wijsenbeek MS. Trends Mol Med. 2023 Dec;29(12):1076-1087. doi: 10.1016/j.molmed.2023.08.010.

Sustainability and Climate Protection in Radiology - An Overview. Palm V, Heye T, Molwitz I, von Stackelberg O, Kauczor HU, Schreyer AG. Rofo. 2023 Nov;195(11):981-988. doi: 10.1055/a-2093-4177.

Week 44 (30.10 - 5.11)

DNMT and HDAC inhibition induces immunogenic neoantigens from human endogenous retroviral element-derived transcripts. Goyal A, Bauer J, Hey J, Papageorgiou DN, Stepanova E, Daskalakis M, Scheid J, Dubbelaar M, Klimovich B, Schwarz D, Märklin M, Roerden M, Lin YY, Ma T, Mücke O, Rammensee HG, Lübbert M, Loayza-Puch F, Krijgsveld J, Walz JS, Plass C. Nat Commun. 2023 Oct 23;14(1):6731. doi: 10.1038/s41467-023-42417-w.

Influence of CT dose reduction on AI-driven malignancy estimation of incidental pulmonary nodules. Peters AA, Solomon JB, von Stackelberg O, Samei E, Alsaihati N, Valenzuela W, Debic M, Heidt C, Huber AT, Christe A, Heverhagen JT, Kauczor HU, Heussel CP, Ebner L, Wielpütz MO. Eur Radiol. 2023 Oct 23. doi: 10.1007/s00330-023-10348-1.

[Prevention, Diagnosis, Therapy, and Follow-up of Lung Cancer - Interdisciplinary Guideline of the German Respiratory Society and the German Cancer Society - Abridged Version]. Schütte W, Gütz S, Nehls W, Blum TG, Brückl W, Buttmann-Schweiger N, Büttner R, Christopoulos P, Delis S, Deppermann KM, Dickgreber N, Eberhardt W, Eggeling S, Fleckenstein J, Flentje M, Frost N, Griesinger F, Grohé C, Gröschel A, Guckenberger M, Hecker E, Hoffmann H, Huber RM, Junker K, Kauczor HU, Kollmeier J, Kraywinkel K, Krüger M, Kugler C, Möller M, Nestle U, Passlick B, Pfannschmidt J, Reck M, Reinmuth N, Rübe C, Scheubel R, Schumann C, Sebastian M, Serke M, Stoelben E, Stuschke M, Thomas M, Tufman A, Vordermark D, Waller C, Wolf J, Wolf M, Wormanns D. Pneumologie. 2023 Oct;77(10):671-813. doi: 10.1055/a-2029-0134.

Vocal cord paralysis as a rare complication of bronchoscopic lung volume reduction. A case series of 5 patients. Benzaquen J, Klooster K, Herth FJ, Rubenstein J, Marquette CH, Slebos DJ, Boutros J. Eur Respir J. 2023 Oct 26:2301722. doi: 10.1183/13993003.01722-2023.

Week 43 (23.10 - 29.10)

Differences and similarities of GTF2I mutated thymomas in different Eurasian ethnic groups. Lang M, Kazdal D, Mohr I, Anamaterou C. Transl Lung Cancer Res. 2023 Sep 28;12(9):1842-1844. doi: 10.21037/tlcr-23-396.

Human APOBEC3B promotes tumor development in vivo including signature mutations and metastases. Durfee C, Temiz NA, Levin-Klein R, Argyris PP, Alsøe L, Carracedo S, Alonso de la Vega A, Proehl J, Holzhauer AM, Seeman ZJ, Liu X, Lin YT, Vogel RI, Sotillo R, Nilsen H, Harris RS. Cell Rep Med. 2023 Oct 17;4(10):101211. doi: 10.1016/j.xcrm.2023.101211.

[Interprofessional weaning boards and weaning consults for long-term ventilated patients: A qualitative study of perceived potential for patient care]. Keller S, Forstner J, Weis A, Biehler E, Trudzinski F, Michels J, Neetz B, Herth F, Schneider A, Ghiani A, Szecsenyi J, Wensing M, Poß-Doering R. Pneumologie. 2023 Oct 19. doi: 10.1055/a-2161-6014.

[Magnetic resonance imaging of the lung : State of the art]. Wucherpfennig L, Kauczor HU, Eichinger M, Wielpütz MO. Radiologie (Heidelb). 2023 Oct 18. doi: 10.1007/s00117-023-01229-1.

Respiratory involvement in connective tissue diseases. Xanthouli P, Echampati I, Lorenz HM, Heussel CP, Benjamin N. Eur J Intern Med. 2023 Oct 14:S0953-6205(23)00337-0. doi: 10.1016/j.ejim.2023.09.016.

Week 42 (16.10 - 22.10)

CYFRA 21-1, CA 125 and CEA provide additional prognostic value in NSCLC patients with stable disease at first CT scan. Muley T, Schneider MA, Meister M, Thomas M, Heußel CP, Kriegsmann M, Holdenrieder S, Wehnl B, Rolny V, Mang A, Gerber R, Herth F. Tumour Biol. 2023 Oct 12. doi: 10.3233/TUB-220042.

Metal Artifact Reduction in Photon-Counting Detector CT: Quantitative Evaluation of Artifact Reduction Techniques. Skornitzke S, Mergen V, Biederer J, Alkadhi H, Do TD, Stiller W, Frauenfelder T, Kauczor HU, Euler A. Invest Radiol. 2023 Oct 9. doi: 10.1097/RLI.0000000000001036.

Prognostic value of tumor markers ProGRP, NSE and CYFRA 21-1 in patients with small cell lung cancer and chemotherapy-induced remission. Muley T, Herth FJ, Heussel CP, Kriegsmann M, Michael T, Meister M, Schneider MA, Wehnl B, Mang A, Holdenrieder S. Tumour Biol. 2023 Oct 12. doi: 10.3233/TUB-230016.

[Statement Paper on the Implementation of a National Organized Program in Germany for the Early Detection of Lung Cancer in Risk Populations Using Low-dose CT Screening Including Management of Screening Findings]. Hoffmann H, Kaaks R, Andreas S, Bauer TT, Barkhausen J, Harth V, Kauczor HU, Pankow W, Welcker K, Vogel-Claussen J, Blum TG; Deutsche Röntgengesellschaft – Vorstand der Deutschen Röntgengesellschaft: Prof. Dr. med. Konstantin Nikolaou, Prof. Dr. med. Jörg Barkhausen, Prof. Dr. med. Christiane Kuhl, Dr. rer. nat. Frank Anton, Dr. med. Stefan Neuman, Prof. Dr. med. Arnd Dörfler, PD Dr. med. Friederike Körber, Prof. Dr. rer. medic. Martin Fiebich, Prof. Dr. med. Gerald Antoch, Dr. med. Kerstin Westphalen, Prof. Dr. Ulrike Attenberger, Prof. Dr. med. Frank Wacker, Prof. Dr. med. Johannes Weßling; Deutsche Gesellschaft für Pneumologie und Beatmungsmedizin – Vorstand der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin: Prof. Dr. med. Wolfram Windisch, Prof. Dr. med. Christian Taube, Prof. Dr. med. Torsten T. Bauer, Prof. Dr. med. Antje Prasse; Deutsche Gesellschaft für Thoraxchirurgie – Vorstand der Deutschen Gesellschaft für Thoraxchirurgie: Dr. med. Katrin Welcker, Dr. med. Ludger Hillejan, Prof. Dr. med. Hans-Stefan Hofmann, PD Dr. med. habil. Robert Scheubel, Dr. med. Erich Hecker, Prof. Dr. med. Corinna Ludwig, Prof. Dr. med. Thorsten Walles, Prof. Dr. med. Hauke Winter. Zentralbl Chir. 2023 Oct 10. doi: 10.1055/a-2178-5907.

Therapeutic drug monitoring of osimertinib in non-small cell lung cancer and short bowel syndrome: a case report. Longuespée R, Kunz J, Fresnais M, Foerster KI, Burhenne J, Thomas M, Kazdal D, Stenzinger A, Christopoulos P, Haefeli WE. Br J Clin Pharmacol. 2023 Oct 10. doi: 10.1111/bcp.15924.

Treating acute exacerbations of COPD with Chinese herbal medicine to aid antibiotic use reduction (Excalibur): a randomised double-blind, placebo-controlled feasibility trial. Willcox ML, Hu XY, Oliver T, Thorne K, Boxall C, He G, Simpson C, Brotherwood B, O'Neil A, Waugh R, Tilt E, Trill J, Goward N, Francis N, Thomas M, Little P, Wilkinson T, Liu JP, Griffiths G, Moore M. Front Pharmacol. 2023 Sep 25;14:1221905. doi: 10.3389/fphar.2023.1221905

Woche 41 (9.10 - 15.10)

Canakinumab as Adjuvant Therapy in Patients With Completely Resected Non-Small-Cell Lung Cancer: Results From the CANOPY-A Double-Blind, Randomized Clinical Trial. Garon EB, Lu S, Goto Y, De Marchi P, Paz-Ares L, Spigel DR, Thomas M, Yang JC, Ardizzoni A, Barlesi F, Orlov S, Yoshioka H, Mountzios G, Khanna S, Bossen C, Carbini M, Turri S, Myers A, Cho BC. J Clin Oncol. 2023 Oct 3:JCO2300910. doi: 10.1200/JCO.23.00910

Current challenges and practical aspects of molecular pathology for non-small cell lung cancers. Hofman P, Berezowska S, Kazdal D, Mograbi B, Ilié M, Stenzinger A, Hofman V. Virchows Arch. 2023 Oct 6. doi: 10.1007/s00428-023-03651-1.

ERS/ESTS/ESTRO/ESR/ESTI/EFOMP statement on management of incidental findings from low dose CT screening for lung cancer. O'Dowd EL, Tietzova I, Bartlett E, Devaraj A, Biederer J, Brambilla M, Brunelli A, Chorostowska J, Decaluwe H, Deruysscher D, De Wever W, Donoghue M, Fabre A, Gaga M, van Geffen W, Hardavella G, Kauczor HU, Kerpel-Fronius A, van Meerbeeck J, Nagavci B, Nestle U, Novoa N, Prosch H, Prokop M, Putora PM, Rawlinson J, Revel MP, Snoeckx A, Veronesi G, Vliegenthart R, Weckbach S, Blum TG, Baldwin DR. Eur Respir J. 2023 Oct 6:2300533. doi: 10.1183/13993003.00533-2023

Mechanisms controlling cellular and systemic iron homeostasis. Galy B, Conrad M, Muckenthaler M. Nat Rev Mol Cell Biol. 2023 Oct 2. doi: 10.1038/s41580-023-00648-1.

Preliminary results from the EMoLung clinical study showing early lung cancer detection by the LC score. Rubio K, Müller JM, Mehta A, Watermann I, Olchers T, Koch I, Wessels S, Schneider MA, Araujo-Ramos T, Singh I, Kugler C, Stoleriu MG, Kriegsmann M, Eichhorn M, Muley T, Merkel OM, Braun T, Ammerpohl O, Reck M, Tresch A, Barreto G. Discov Oncol. 2023 Oct 3;14(1):181. doi: 10.1007/s12672-023-00799-9.

Qualitative and quantitative evaluation of computed tomography changes in adults with cystic fibrosis treated with elexacaftor-tezacaftor-ivacaftor: a retrospective observational study. Dettmer S, Weinheimer O, Sauer-Heilborn A, Lammers O, Wielpütz MO, Fuge J, Welte T, Wacker F, Ringshausen FC. Front Pharmacol. 2023 Sep 21;14:1245885. doi: 10.3389/fphar.2023.1245885.

Woche 40 (2.10 - 8.10)

Impact of Heated Tobacco Products, E-Cigarettes, and Combustible Cigarettes on Small Airways and Arterial Stiffness. Goebel I, Mohr T, Axt PN, Watz H, Trinkmann F, Weckmann M, Drömann D, Franzen KF. Toxics. 2023 Sep 6;11(9):758. doi: 10.3390/toxics11090758.

Pulmonary arterial wedge pressure increase during exercise in patients diagnosed with pulmonary arterial or chronic thromboembolic pulmonary hypertension. Müller J, Mayer L, Schneider SR, Titz A, Schwarz EI, Saxer S, Furian M, Grünig E, Ulrich S, Lichtblau M. ERJ Open Res. 2023 Sep 25;9(5):00379-2023. doi: 10.1183/23120541.00379-2023.

Standards for the care of people with cystic fibrosis (CF): A timely and accurate diagnosis. Castellani C, Simmonds NJ, Barben J, Addy C, Bevan A, Burgel PR, Drevinek P, Gartner S, Gramegna A, Lammertyn E, Landau EEC, Middleton PG, Plant BJ, Smyth AR, van Koningsbruggen-Rietschel S, Girodon E, Kashirskaya N, Munck A, Nährlich L, Raraigh K, Sermet-Gaudelus I, Sommerburg O, Southern KW. J Cyst Fibros. 2023 Sep 27:S1569-1993(23)00912-8. doi: 10.1016/j.jcf.2023.09.008.

Week 39 (25.09 - 1.10)

Analysis of rare fusions in NSCLC: Genomic architecture and clinical implications. Seker-Cin H, Tay TKY, Kazdal D, Kluck K, Ball M, Neumann O, Winter H, Herth F, Heußel CP, Savai R, Schirmacher P, Thomas M, Budczies J, Allgäuer M, Christopoulos P, Stenzinger A, Volckmar AL. Lung Cancer. 2023 Oct;184:107317. doi: 10.1016/j.lungcan.2023.107317.

Costs of Weaning Failure: A Prospective, Multicentre, Controlled, Non-Randomised, Interventional Study on Economic Implications for the German Health Care System. Michels JD, Trudzinski FC, Bornitz F, Ewert R, Müller M, Trinkmann F, Schellenberg M, Windisch W, Herth FJF. Respiration. 2023;102(9):813-820. doi: 10.1159/000533333.

Influenza virus decreases albumin uptake and megalin expression in alveolar epithelial cells. Alberro-Brage A, Kryvenko V, Malainou C, Günther S, Morty RE, Seeger W, Herold S, Samakovlis C, Vadász I. Front Immunol. 2023 Sep 1;14:1260973. doi: 10.3389/fimmu.2023.1260973.

Management of a Pregnant ALK-Positive Lung Cancer Patient With Alectinib-Induced Pneumonitis and Bilateral Globus Pallidus Necrosis Postpartum. Bochtler T, Christopoulos P, Schlamp K, Winkler F, Krämer A. Clin Lung Cancer. 2023 Aug 30:S1525-7304(23)00181-X. doi: 10.1016/j.cllc.2023.08.016.

Multicenter Standardization of Phase-Resolved Functional Lung MRI in Patients With Suspected Chronic Thromboembolic Pulmonary Hypertension. Moher Alsady T, Voskrebenzev A, Behrendt L, Olsson K, Heußel CP, Gruenig E, Gall H, Ghofrani A, Roller F, Harth S, Marshall H, Hughes PJC, Wild J, Swift AJ, Kiely DG, Behr J, Dinkel J, Beitzke D, Lang IM, Schmidt KH, Kreitner KF, Frauenfelder T, Ulrich S, Hamer OW, Vogel-Claussen J. J Magn Reson Imaging. 2023 Sep 21. doi: 10.1002/jmri.28995

Potential of ChatGPT and GPT-4 for Data Mining of Free-Text CT Reports on Lung Cancer. Fink MA, Bischoff A, Fink CA, Moll M, Kroschke J, Dulz L, Heußel CP, Kauczor HU, Weber TF. Radiology. 2023 Sep;308(3):e231362. doi: 10.1148/radiol.231362.

Sex and anti-inflammatory treatment affect outcome of melanoma and non-small cell lung cancer patients with rheumatic immune-related adverse events. Gente K, Diekmann L, Daniello L, Will J, Feisst M, Olsavszky V, Günther J, Lorenz HM, Souto-Carneiro MM, Hassel JC, Christopoulos P, Leipe J. J Immunother Cancer. 2023 Sep;11(9):e007557. doi: 10.1136/jitc-2023-007557.

Week 38 (18.09 - 24.09)

Design of a phase III, double-blind, randomised, placebo-controlled trial of BI 1015550 in patients with progressive pulmonary fibrosis (FIBRONEER-ILD). Maher TM, Assassi S, Azuma A, Cottin V, Hoffmann-Vold AM, Kreuter M, Oldham JM, Richeldi L, Valenzuela C, Wijsenbeek MS, Coeck C, Schlecker C, Voss F, Wachtlin D, Martinez FJ. BMJ Open Respir Res. 2023 Sep;10(1):e001580. doi: 10.1136/bmjresp-2022-001580.

Effects of sotatercept on haemodynamics and right heart function: analysis of STELLAR trial. Souza R, Badesch DB, Ghofrani HA, Gibbs JSR, Gomberg-Maitland M, McLaughlin VV, Preston IR, Waxman AB, Grünig E, Kopeć G, Meyer G, Olsson KM, Rosenkranz S, Lin J, Johnson-Levonas AO, de Oliveira Pena J, Humbert M, Hoeper MM. Eur Respir J. 2023 Sep 11:2301107. doi: 10.1183/13993003.01107-2023.

Interventional pneumology-Where we have come from and where we are going. Herth FJF, Kontogianni K, Brock JM. Respirology. 2023 Sep 14. doi: 10.1111/resp.14602.

Week 37 (11.09 - 17.09)

Cluster Analyses From the Real-World NOVELTY Study: Six Clusters Across the Asthma-COPD Spectrum. Hughes R, Rapsomaniki E, Bansal AT, Vestbo J, Price D, Agustí A, Beasley R, Fageras M, Alacqua M, Papi A, Müllerová H, Reddel HK; NOVELTY Scientific Community; NOVELTY study investigators. J Allergy Clin Immunol Pract. 2023 Sep;11(9):2803-2811. doi: 10.1016/j.jaip.2023.05.013.

Endobronchial lung volume reduction with valves reduces exacerbations in severe emphysema patients. Brock JM, Böhmker F, Schuster PU, Eberhardt R, Gompelmann D, Kontogianni K, Dittrich S, Benjamin N, Herth F. Respir Med. 2023 Sep 4;218:107399. doi: 10.1016/j.rmed.2023.107399.

Impact of ⁶⁸Ga-FAPI PET/CT on Staging and Oncologic Management in a Cohort of 226 Patients with Various Cancers. Koerber SA, Röhrich M, Walkenbach L, Liermann J, Choyke PL, Fink C, Schroeter C, Spektor AM, Herfarth K, Walle T, Calais J, Kauczor HU, Jaeger D, Debus J, Haberkorn U, Giesel FL. J Nucl Med. 2023 Sep 7:jnumed.123.266046. doi: 10.2967/jnumed.123.266046.

The Proton Is Not Enough: Opportunities of Combined Multinuclear MRI for Lung Functional Imaging. Wielpütz MO. Chest. 2023 Sep;164(3):572-573. doi: 10.1016/j.chest.2023.03.038.

Week 36 (04.09 - 10.09)

Anti-acid therapy in SSc-associated interstitial lung disease: long-term outcomes from the German Network for Systemic Sclerosis. Kreuter M, Bonella F, Blank N, Riemekasten G, Müller-Ladner U, Henes J, Siegert E, Günther C, Kötter I, Pfeiffer C, Schmalzing M, Zeidler G, Korsten P, Susok L, Juche A, Worm M, Jandova I, Ehrchen J, Sunderkötter C, Keyßer G, Ramming A, Schmeiser T, Kreuter A, Kuhr K, Lorenz HM, Moinzadeh P, Hunzelmann N. Rheumatology (Oxford). 2023 Sep 1;62(9):3067-3074. doi: 10.1093/rheumatology/kead023.

Decline in forced vital capacity as a surrogate for mortality in patients with pulmonary fibrosis. Maher TM, Stowasser S, Voss F, Bendstrup E, Kreuter M, Martinez FJ, Sime PJ, Stock C. Respirology. 2023 Aug 30. doi: 10.1111/resp.14579.

[Patient-centered, value-based management of incidental findings in radiology]. Weckbach S, Wielpütz MO, von Stackelberg O. Radiologie (Heidelb). 2023 Sep;63(9):657-664. doi: 10.1007/s00117-023-01200-0.

[Sustainability and climate protection : Implications on patient-centered care in radiology]. Palm V, Molwitz I, Rischen R, Westphalen K, Kauczor HU, Schreyer AG. Radiologie (Heidelb). 2023 Sep;63(9):672-678. doi: 10.1007/s00117-023-01199-4.

Week 35 (28.08 - 03.09)

Distinguishing bronchoscopically observed anatomical positions of airway under by convolutional neural network. Chen C, Herth FJ, Zuo Y, Li H, Liang X, Chen Y, Ren J, Jian W, Zhong C, Li S. Ther Adv Chronic Dis. 2023 Aug 23;14:20406223231181495. doi: 10.1177/20406223231181495.

Influence of cell type specific infectivity and tissue composition on SARS-CoV-2 infection dynamics within human airway epithelium. Raach B, Bundgaard N, Haase MJ, Starruß J, Sotillo R, Stanifer ML, Graw F. PLoS Comput Biol. 2023 Aug 11;19(8):e1011356. doi: 10.1371/journal.pcbi.1011356.

[Robot-assisted Thoracic Surgery: Learning Curve and Cost Analysis in a German High-Volume Centre]. Eichhorn M, Rotärmel A, Haag J, Baum P, Winter H. Zentralbl Chir. 2023 Aug;148(S 01):S26-S32. doi: 10.1055/a-1921-9058.

Week 34 (21.08 - 27.08)

Analysis of rare fusions in NSCLC: Genomic architecture and clinical implications. Seker-Cin H, Tay TKY, Kazdal D, Kluck K, Ball M, Neumann O, Winter H, Herth F, Heußel CP, Savai R, Schirmacher P, Thomas M, Budczies J, Allgäuer M, Christopoulos P, Stenzinger A, Volckmar AL. Lung Cancer. 2023 Jul 27;184:107317. doi: 10.1016/j.lungcan.2023.107317.

Design of a phase III, double-blind, randomised, placebo-controlled trial of BI 1015550 in patients with idiopathic pulmonary fibrosis (FIBRONEER-IPF). Richeldi L, Azuma A, Cottin V, Kreuter M, Maher TM, Martinez FJ, Oldham JM, Valenzuela C, Gordat M, Liu Y, Stowasser S, Zoz DF, Wijsenbeek MS. BMJ Open Respir Res. 2023 Aug;10(1):e001563. doi: 10.1136/bmjresp-2022-001563.

Elexacaftor/Tezacaftor/Ivacaftor Improves Bronchial Artery Dilatation Detected by Magnetic Resonance Imaging in Patients with Cystic Fibrosis. Wucherpfennig L, Triphan SMF, Wege S, Kauczor HU, Heussel CP, Sommerburg O, Stahl M, Mall MA, Eichinger M, Wielpütz MO. Ann Am Thorac Soc. 2023 Aug 14. doi: 10.1513/AnnalsATS.202302-168OC.

Krebs von den Lungen-6 as a Potential Predictive Biomarker in Fibrosing Interstitial Lung Diseases. Lederer C, Mayer K, Somogyi V, Kriegsmann K, Kriegsmann M, Buschulte K, Polke M, Findeisen P, Herth F, Kreuter M. Respiration. 2023 Aug 16:1-10. doi: 10.1159/000531945.

Week 33 (14.08 - 20.08)

Comorbidity in limited disease small-cell lung cancer: Age-adjusted Charlson comorbidity index and its association with overall survival following chemoradiotherapy. Fink CA, Weykamp F, Adeberg S, Bozorgmehr F, Christopoulos P, Lang K, König L, Hörner-Rieber J, Thomas M, Steins M, El-Shafie RA, Rieken S, Bernhardt D, Debus J. Clin Transl Radiat Oncol. 2023 Jul 24;42:100665. doi: 10.1016/j.ctro.2023.100665.

Impact of elexacaftor/tezacaftor/ivacaftor on lung function, nutritional status, pulmonary exacerbation frequency and sweat chloride in people with cystic fibrosis: real-world evidence from the German CF Registry. Sutharsan S, Dillenhoefer S, Welsner M, Stehling F, Brinkmann F, Burkhart M, Ellemunter H, Dittrich AM, Smaczny C, Eickmeier O, Kappler M, Schwarz C, Sieber S, Naehrig S, Naehrlich L; German CF Registry of the Mukoviszidose e.V. and participating CF sites. Lancet Reg Health Eur. 2023 Jul 28;32:100690. doi: 10.1016/j.lanepe.2023.100690.

Lung Cancer Screening With Low-Dose Computed Tomography. Reck M, Dettmer S, Kauczor HU, Kaaks R, Reinmuth N, Vogel-Claussen J. Dtsch Arztebl Int. 2023 Jun 9;120(23):387-392. doi: 10.3238/arztebl.m2023.0099.

Tackling the challenge of brain involvement in driver-negative non-small cell lung cancer. Christopoulos P. Transl Lung Cancer Res. 2023 Jul 31;12(7):1364-1368. doi: 10.21037/tlcr-23-347.

Week 32 (7.08 - 13.08)

ADPGK-AS1 long noncoding RNA switches macrophage metabolic and phenotypic state to promote lung cancer growth. Karger A, Mansouri S, Leisegang MS, Weigert A, Günther S, Kuenne C, Wittig I, Zukunft S, Klatt S, Aliraj B, Klotz LV, Winter H, Mahavadi P, Fleming I, Ruppert C, Witte B, Alkoudmani I, Gattenlöhner S, Grimminger F, Seeger W, Pullamsetti SS, Savai R. EMBO J. 2023 Aug 7:e111620. doi: 10.15252/embj.2022111620.

Effects of Lumacaftor/Ivacaftor on Cystic Fibrosis Disease Progression in Children 2 through 5 Years of Age Homozygous for F508del-CFTR: A Phase 2 Placebo-controlled Clinical Trial. Stahl M, Roehmel J, Eichinger M, Doellinger F, Naehrlich L, Kopp MV, Dittrich AM, Lee C, Sommerburg O, Tian S, Xu T, Wu P, Joshi A, Ray P, Duncan ME, Wielpütz MO, Mall MA. Ann Am Thorac Soc. 2023 Aug;20(8):1144-1155. doi: 10.1513/AnnalsATS.202208-684OC.

GOLD stage-specific phenotyping of emphysema and airway disease using quantitative computed tomography. Konietzke P, Brunner C, Konietzke M, Wagner WL, Weinheimer O, Heußel CP, Herth FJF, Trudzinski F, Kauczor HU, Wielpütz MO. Front Med (Lausanne). 2023 Jul 18;10:1184784. doi: 10.3389/fmed.2023.1184784.

Long-Term Safety, Outcome, and Clinical Effects of Subcutaneous and Intravenous Treprostinil Treatment in Patients with Severe Chronic Pulmonary Arterial Hypertension. Harutyunova S, Benjamin N, Eichstaedt C, Marra AM, Xanthouli P, Nagel C, Grünig E, Egenlauf B. Respiration. 2023 Aug 4:1-12. doi: 10.1159/000531169.

Week 31 (31.07 - 6.08)

Patient-level factors predictive of interstitial lung disease in rheumatoid arthritis: a systematic review. Matteson EL, Matucci-Cerinic M, Kreuter M, Burmester GR, Dieudé P, Emery P, Allanore Y, Pope J, Khanna D. RMD Open. 2023 Jul;9(3):e003059. doi: 10.1136/rmdopen-2023-003059.

Week 30 (24.07 - 30.07)

Comparison of Rescue Medication Prescriptions in Patients with Chronic Obstructive Pulmonary Disease Receiving Umeclidinium/Vilanterol versus Tiotropium Bromide/Olodaterol in Routine Clinical Practice in England. Requena G, Czira A, Banks V, Wood R, Tritton T, Castillo CM, Yeap J, Wild R, Compton C, Rothnie KJ, Herth F, Quint JK, Ismaila AS. Int J Chron Obstruct Pulmon Dis. 2023 Jul 13;18:1431-1444. doi: 10.2147/COPD.S411437.

Magnetic Resonance Imaging of Lung Perfusion. Triphan SMF, Bauman G, Konietzke P, Konietzke M, Wielpütz MO; International Workshop for Pulmonary Functional Imaging (IWPFI). J Magn Reson Imagin. 2023 Jul 19. doi: 10.1002/jmri.28912.

Prognostic Impact of the Immune-Cell Infiltrate in N1-Positive Non-Small-Cell Lung Cancer. Eichhorn F, Weigert A, Nandigama R, Klotz LV, Wilhelm J, Kriegsmann M, Allgäuer M, Muley T, Christopoulos P, Savai R, Eichhorn ME, Winter H. Clin Lung Cancer. 2023 Jun 28:S1525-7304(23)00139-0. doi: 10.1016/j.cllc.2023.06.013.

Treatment strategies and survival of patients with connective tissue disease and pulmonary arterial hypertension: A COMPERA analysis. Distler O, Ofner C, Huscher D, Jordan S, Ulrich S, Stähler G, Grünig E, Held M, Ghofrani HA, Claussen M, Lange TJ, Klose H, Rosenkranz S, Vonk-Noordegraaf A, Vizza CD, Delcroix M, Opitz C, Pausch C, Scelsi L, Neurohr C, Olsson KM, Coghlan JG, Halank M, Skowasch D, Behr J, Milger K, Remppis BA, Skride A, Jureviciene E, Gumbiene L, Miliauskas S, Löffler-Ragg J, Wilkens H, Pittrow D, Hoeper MM, Ewert R. Rheumatology (Oxford). 2023 Jul 18:kead360. doi: 10.1093/rheumatology/kead360.

Week 29 (17.07 - 23.07)

Analysis of acute COVID-19 including chronic morbidity: protocol for the deep phenotyping National Pandemic Cohort Network in Germany (NAPKON-HAP). Steinbeis F, Thibeault C, Steinbrecher S, Ahlgrimm Y, Haack IA, August D, Balzuweit B, Bellinghausen C, Berger S, Chaplinskaya-Sobol I, Cornely O, Doeblin P, Endres M, Fink C, Finke C, Frank S, Hanß S, Hartung T, Hellmuth JC, Herold S, Heuschmann P, Heyckendorf J, Heyder R, Hippenstiel S, Hoffmann W, Kelle SU, Knape P, Koehler P, Kretzler L, Leistner DM, Lienau J, Lorbeer R, Lorenz-Depiereux B, Lüttke CD, Mai K, Merle U, Meyer-Arndt LA, Miljukov O, Muenchhoff M, Müller-Plathe M, Neuhann J, Neuhauser H, Nieters A, Otte C, Pape D, Pinto RM, Pley C, Pudszuhn A, Reuken P, Rieg S, Ritter P, Rohde G, Rönnefarth M, Ruzicka M, Schaller J, Schmidt A, Schmidt S, Schwachmeyer V, Schwanitz G, Seeger W, Stahl D, Stobäus N, Stubbe HC, Suttorp N, Temmesfeld B, Thun S, Triller P, Trinkmann F, Vadasz I, Valentin H, Vehreschild M, von Kalle C, von Lilienfeld-Toal M, Weber J, Welte T, Wildberg C, Wizimirski R, Zvork S, Sander LE, Vehreschild J, Zoller T, Kurth F, Witzenrath M. Infection. 2023 Jul 11. doi: 10.1007/s15010-023-02057-0.

Bilateral lung transplantation for pediatric pulmonary arterial hypertension: perioperative management and one-year follow-up. Jack T, Carlens J, Diekmann F, Hasan H, Chouvarine P, Schwerk N, Müller C, Wieland I, Tudorache I, Warnecke G, Avsar M, Horke A, Ius F, Bobylev D, Hansmann G. Front Cardiovasc Med. 2023 Jun 27;10:1193326. doi: 10.3389/fcvm.2023.1193326.

Early Detection of Lung Cancer using small RNAs. Sikosek T, Horos R, Trudzinski F, Jehn J, Frank M, Rajakumar T, Klotz LV, Mercaldo N, Kahraman M, Heuvelman M, Taha Y, Gerwing J, Skottke J, Daniel-Moreno A, Sanchez-Delgado M, Bender S, Rudolf C, Hinkfoth F, Tikk K, Schenz J, Weigand MA, Feindt P, Schumann C, Christopoulos P, Winter H, Kreuter M, Schneider MA, Muley T, Walterspacher S, Schuler M, Darwiche K, Taube C, Hegedus B, Rabe KF, Rieger-Christ K, Jacobsen FL, Aigner C, Reck M, Bankier AA, Sharma A, Steinkraus BR. J Thorac Oncol. 2023 Jul 10:S1556-0864(23)00670-6. doi: 10.1016/j.jtho.2023.07.005.

FOXM1 is critical for the fitness recovery of chromosomally unstable cells. Pan F, Chocarro S, Ramos M, Chen Y, Alonso de la Vega A, Somogyi K, Sotillo R. Cell Death Dis. 2023 Jul 14;14(7):430. doi: 10.1038/s41419-023-05946-2.

Is the internet a sufficient source of information on sarcoidosis? Buschulte K, Höger P, Ganter C, Wijsenbeek M, Kahn N, Kriegsmann K, Wilkens FM, Fisher JH, Ryerson CJ, Herth FJF, Kreuter M. Front Med (Lausanne). 2023 Jun 27;10:1217146. doi: 10.3389/fmed.2023.1217146.

The HDAC2-SP1 Axis Orchestrates Protumor Macrophage Polarization. Zheng X, Sarode P, Weigert A, Turkowski K, Chelladurai P, Günther S, Kuenne C, Winter H, Stenzinger A, Reu S, Grimminger F, Stiewe T, Seeger W, Pullamsetti SS, Savai R. Cancer Res. 2023 Jul 14;83(14):2345-2357. doi: 10.1158/0008-5472.CAN-22-1270.

Week 28 (10.07 - 16.07)

Bronchoscopic transparenchymal nodule access in the diagnosis and management of pulmonary nodules. Zhang Q, Wu X, Yang H, Sun Y, Wang Z, Yang L, Wei N, Zhang Y, Yang Y, Zhao X, Herth FJ, Zhang X. Chin Med J (Engl). 2023 Jul 5;136(13):1615-1617. doi: 10.1097/CM9.0000000000002355.

Comutations and KRASG12C Inhibitor Efficacy in Advanced NSCLC. Negrao MV, Araujo HA, Lamberti G, Cooper AJ, Akhave NS, Zhou T, Delasos L, Hicks JK, Aldea M, Minuti G, Hines J, Aredo JV, Dennis MJ, Chakrabarti T, Scott SC, Bironzo P, Scheffler M, Christopoulos P, Stenzinger A, Riess JW, Kim SY, Goldberg SB, Li M, Wang Q, Qing Y, Ni Y, Do MT, Lee R, Ricciuti B, Alessi JV, Wang J, Resuli B, Landi L, Tseng SC, Nishino M, Digumarthy SR, Rinsurongkawong W, Rinsurongkawong V, Vaporciyan AA, Blumenschein GR, Zhang J, Owen DH, Blakely CM, Mountzios G, Shu CA, Bestvina CM, Garassino MC, Marrone KA, Gray JE, Patel SP, Cummings AL, Wakelee HA, Wolf J, Scagliotti GV, Cappuzzo F, Barlesi F, Patil PD, Drusbosky L, Gibbons DL, Meric-Bernstam F, Lee JJ, Heymach JV, Hong DS, Heist RS, Awad MM, Skoulidis F. Cancer Discov. 2023 Jul 7;13(7):1556-1571. doi: 10.1158/2159-8290.CD-22-1420.

Defining the Clinical Validity of Genes Reported to Cause Pulmonary Arterial Hypertension. Welch CL, Aldred MA, Balachandar S, Dooijes D, Eichstaedt CA, Graf S, Houweling AC, Machado RD, Pandya D, Prapa M, Shaukat M, Southgate L, Tenorio-Castano J; ClinGen PH VCEP; Chung WK; International Consortium for Genetic Studies in Pulmonary Arterial Hypertension (PAH-ICON) at the Pulmonary Vascular Research Institute (PVRI). Genet Med. 2023 Jul 5:100925. doi: 10.1016/j.gim.2023.100925.

Implementation and evaluation of ultra-low dose CT in early cystic fibrosis lung disease. Bayfield KJ, Weinheimer O, Boyton C, Fitzpatrick R, Middleton A, Kennedy B, Blaxland A, Jayasuriya G, Caplain N, Issa H, Goetti R, Wielpütz MO, Yu L, Galban CJ, Robinson TE, Bartholmai B, Fitzgerald D, Selvadurai H, Robinson PD. Eur Respir J. 2023 Jul 7;62(1):2300286. doi: 10.1183/13993003.00286-2023. Print 2023 Jul.

Longitudinal Effects of Elexacaftor/Tezacaftor/Ivacaftor on Sputum Viscoelastic Properties, Airway Infection and Inflammation in Patients with Cystic Fibrosis. Schaupp L, Addante A, Völler M, Fentker K, Kuppe A, Bardua M, Duerr J, Piehler L, Röhmel J, Thee S, Kirchner M, Ziehm M, Lauster D, Haag R, Gradzielski M, Stahl M, Mertins P, Boutin S, Graeber SY, Mall MA. Eur Respir J. 2023 Jul 6:2202153. doi: 10.1183/13993003.02153-2022.

Reporting Standards for Diagnostic Testing: Guidance for Authors From Editors of Respiratory, Sleep, and Critical Care Journals. Ost DE, Feller-Kopman DJ, Gonzalez AV, Grosu HB, Herth F, Mazzone P, Park JES, Porcel JM, Shojaee S, Tsiligianni I, Vachani A, Bernstein J, Branson R, Flume PA, Akdis CA, Kolb M, Portela EB, Smyth A. J Bronchology Interv Pulmonol. 2023 Jul 1;30(3):207-222. doi: 10.1097/LBR.0000000000000920.

Week 27 (03.07 - 09.07)

Implementation and Evaluation of Ultra Low-Dose CT in Early Cystic Fibrosis Lung Disease. Bayfield KJ, Weinheimer O, Boyton C, Fitzpatrick R, Middleton A, Kennedy B, Blaxland A, Jayasuriya G, Caplain N, Issa H, Goetti R, Wielpütz MO, Yu L, Galban CJ, Robinson TE, Bartholmai B, Fitzgerald D, Selvadurai H, Robinson PD. Eur Respir J. 2023 Jun 29:2300286. doi: 10.1183/13993003.00286-2023.

Pembrolizumab Alone or With Chemotherapy for 70+ Year-Old Lung Cancer Patients: A Retrospective Study. Blasi M, Kuon J, Shah R, Bozorgmehr F, Eichhorn F, Liersch S, Stenzinger A, Heußel CP, Herth FJ, Thomas M, Christopoulos P. Clin Lung Cancer. 2023 Jun 22:S1525-7304(23)00136-5. doi: 10.1016/j.cllc.2023.06.010.

Week 25 (19.06 - 25.06)

Accurate tumor purity determination is critical for the analysis of homologous recombination deficiency (HRD). Menzel M, Endris V, Schwab C, Kluck K, Neumann O, Beck S, Ball M, Schaaf C, Fröhling S, Lichtner P, Schirmacher P, Kazdal D, Stenzinger A, Budczies J. Transl Oncol. 2023 Jun 14;35:101706. doi: 10.1016/j.tranon.2023.101706.

Impact of total ischaemic time and disease severity class on graft function after bilateral lung transplantation. Aburahma K, de Manna ND, Boethig D, Franz M, Iablonskii P, Heise EL, Bobylev D, Avsar M, Greer M, Schwerk N, Sommer W, Welte T, Haverich A, Warnecke G, Kuehn C, Salman J, Ius F. Eur J Cardiothorac Surg. 2023 Jun 1;63(6):ezad196. doi: 10.1093/ejcts/ezad196.

Reanalysis of N₂-lung clearance index and the comparison to SF₆-lung clearance index and magnetic resonance imaging. Steinke E, Wielpütz MO, Joachim C, Mall MA, Stahl M. J Cyst Fibros. 2023 Jun 13:S1569-1993(23)00136-4. doi: 10.1016/j.jcf.2023.05.006.

Symptom Burden, Health Status, and Productivity in Patients with Uncontrolled and Controlled Severe Asthma in NOVELTY. Ding B, Chen S, Srivastava D, Quinton A, Cook W, Papi A, Reddel HK; List of NOVELTY Scientific Community members; List of NOVELTY study investigators. J Asthma Allergy. 2023 Jun 11;16:611-624. doi: 10.2147/JAA.S401445.

Woche 24 (12.06 - 18.06)

European survey of newborn bloodspot screening for CF: opportunity to address challenges and improve performance. Munck A, Berger DO, Southern KW, Carducci C, de Winter-de Groot KM, Gartner S, Kashirskaya N, Linnane B, Proesmans M, Sands D, Sommerburg O, Castellani C, Barben J; European CF Society Neonatal Screening Working Group (ECFS NSWG). J Cyst Fibros. 2023 May;22(3):484-495. doi: 10.1016/j.jcf.2022.09.012.

Is iron deficiency caused by BMPR2 mutations or dysfunction in pulmonary arterial hypertension patients? Theobald V, Grünig E, Benjamin N, Seyfarth HJ, Halank M, Schneider MA, Richtmann S, Kazdal D, Hinderhofer K, Xanthouli P, Egenlauf B, Harutyunova S, Hoeper MM, Jonigk D, Sparla R, Muckenthaler MU, Eichstaedt CA. Pulm Circ. 2023 Jun 7;13(2):e12242. doi: 10.1002/pul2.12242.

Week 23 (05.06 - 11.06)

Clinical trial simulations in pulmonary fibrosis: patient-focused insights and adaptations. Jones S, Flewett M, Flewett R, Lee S, Vick B, Thompson M, Pinnetti S, Zoz DF, Hoffmann-Vold AM, Kreuter M, Maher TM. ERJ Open Res. 2023 May 30;9(3):00602-2022. doi: 10.1183/23120541.00602-2022.

Tepotinib Treatment in Patients With MET Exon 14-Skipping Non-Small Cell Lung Cancer: Long-term Follow-up of the VISION Phase 2 Nonrandomized Clinical Trial. Mazieres J, Paik PK, Garassino MC, Le X, Sakai H, Veillon R, Smit EF, Cortot AB, Raskin J, Viteri S, Wu YL, Yang JCH, Ahn MJ, Ma R, Zhao J, O'Brate A, Berghoff K, Bruns R, Otto G, Johne A, Felip E, Thomas M. JAMA Oncol. 2023 Jun 4. doi: 10.1001/jamaoncol.2023.1962.

Week 22 (29.05 - 04.06)

Airway Stents from Now to the Future: A Narrative Review. Li L, Zhang X, Shi J, Chen Y, Wan H, Herth FJ, Luo F. Respiration. 2023 May 12:1-10. doi: 10.1159/000530421.

Endobronchial Valve Replacements in Patients with Advanced Emphysema After Endoscopic Lung Volume Reduction. Brock JM, Schuster PU, Böhmker F, Eberhardt R, Gompelmann D, Kontogianni K, Trudzinski F, Benjamin N, Herth F. Int J Chron Obstruct Pulmon Dis. 2023 May 19;18:933-943. doi: 10.2147/COPD.S408674.

ERS International Congress 2022: highlights from the Paediatrics Assembly. Ardura-Garcia C, Kainz K, Mallet MC, Petrarca L, Rodman Berlot J, Slaats M, Streibel C, Vijverberg S, Williams EE, Goutaki M, Gray DM, Lavizzari A, Morty RE, Proesmans M, Schramm D, Stahl M, Zacharasiewicz A, Moeller A, Pijnenburg MW. ERJ Open Res. 2023 May 22;9(3):00653-2022. doi: 10.1183/23120541.00653-2022.

HELP - Heidelberg decision aid for lung cancer patients: a randomized controlled clinical trial. Deis N, Unsöld L, Siegle A, Krisam J, Thomas M, Villalobos M. Trials. 2023 May 25;24(1):356. doi: 10.1186/s13063-023-07365-2.

Important steps towards a big change for lung health: a joint approach by the European Respiratory Society, the European Society of Radiology and their partners to facilitate implementation of the European Union's new recommendations on lung cancer screening. Ward B, Koziar Vašáková M, Robalo Cordeiro C, Yorgancioğlu A, Chorostowska-Wynimko J, Blum TG, Kauczor HU, Samarzija M, Henschke C, Wheelock C, Grigg J, Andersen ZJ, Koblížek V, Májek O, Odemyr M, Powell P, Seijo LM. ERJ Open Res. 2023 May 9;9(3):00026-2023. doi: 10.1183/23120541.00026-2023.

Lung transplantation despite preformed donor-specific anti-HLA antibodies: 9-year single-center experience. Heise EL, Chichelnitskiy E, Greer M, Franz M, Aburahma K, Iablonskii P, de Manna ND, Christoph S, Verboom M, Hallensleben M, Boethig D, Avsar M, Welte T, Schwerk N, Sommer W, Haverich A, Warnecke G, Kuehn C, Falk C, Salman J, Ius F. Am J Transplant. 2023 May 22:S1600-6135(23)00461-6. doi: 10.1016/j.ajt.2023.04.034.

SMARCA4-Deficient Undifferentiated Tumor Achieved by Transbronchial Mediastinal Cryobiopsy Additional to Needle Aspiration. Zhang J, Zhou D, Fu WL, Guo JR, Cheng TL, Jiang YQ, Huang ZS, Herth FJ, Fan Y. Respiration. 2023 May 24:1. doi: 10.1159/000529986.

Week 21 (22.05 - 28.05)

Developing a Pan-European Technical Standard for a Comprehensive High-quality Lung Cancer CT Screening Program. An ERS Technical Standard. Baldwin D, O'Dowd E, Tietzova I, Kerpel-Fronius A, Heuvelmans M, Snoeckx A, Ashraf H, Kauczor HU, Nagavci B, Oudkerk M, Putora PM, Rzyman W, Veronesi G, Borondy-Kitts A, Gratacos AR, van Meerbeeck J, Blum TG. Eur Respir J. 2023 May 18:2300128. doi: 10.1183/13993003.00128-2023.

Lung Adenocarcinoma Diagnosed at a Younger Age Is Associated with Advanced Stage, Female Sex, and Ever-Smoker Status, in Patients Treated with Lung Resection. Dragani TA, Muley T, Schneider MA, Kobinger S, Eichhorn M, Winter H, Hoffmann H, Kriegsmann M, Noci S, Incarbone M, Tosi D, Franzi S, Colombo F. Cancers (Basel). 2023 Apr 21;15(8):2395. doi: 10.3390/cancers15082395.

Lung Cancer Screening With Low-Dose Computed Tomography: Current Status in Germany. Reck M, Dettmer S, Kauczor HU, Kaaks R, Reinmuth N, Vogel-Claussen J. Dtsch Arztebl Int. 2023 Jun 29;(Forthcoming):arztebl.m2023.0099. doi: 10.3238/arztebl.m2023.0099.

Spatial profiling of the microenvironment reveals low intratumoral heterogeneity and STK11-associated immune evasion in therapy-naïve lung adenocarcinomas. Goldschmid H, Kluck K, Ball M, Kirchner M, Allgäuer M, Winter H, Herth F, Heußel CP, Pullamsetti SS, Savai R, Yong TTK, Schirmacher P, Peters S, Thomas M, Christopoulos P, Budczies J, Stenzinger A, Kazdal D. Lung Cancer. 2023 Jun;180:107212. doi: 10.1016/j.lungcan.2023.107212.

Surgical cytoreduction and hyperthermic intrathoracic chemotherapy for thymic tumours with pleural spread is effective on survival: results from the multicentre German HITOC-study. Ried M, Hassan M, Passlick B, Schmid S, Markowiak T, Müller K, Huppertz G, Koller M, Winter H, Klotz LV, Hatz R, Kovács J, Zimmermann J, Hofmann HS, Eichhorn ME. Interdiscip Cardiovasc Thorac Surg. 2023 Feb 10:ivad032. doi: 10.1093/icvts/ivad032.

Week 20 (15.05 - 21.05)

Automated lung cancer assessment on 18F-PET/CT using Retina U-Net and anatomical region segmentation. Weikert T, Jaeger PF, Yang S, Baumgartner M, Breit HC, Winkel DJ, Sommer G, Stieltjes B, Thaiss W, Bremerich J, Maier-Hein KH, Sauter AW. Eur Radiol. 2023 Jun;33(6):4270-4279. doi: 10.1007/s00330-022-09332-y.

Comparative Effectiveness of Umeclidinium/Vilanterol versus Inhaled Corticosteroid/Long-Acting β₂-Agonist in Patients with Chronic Obstructive Pulmonary Disease in a Primary Care Setting in England. Czira A, Requena G, Banks V, Wood R, Tritton T, Castillo CM, Yeap J, Wild R, Compton C, Rothnie KJ, Herth F, Quint JK, Ismaila AS. Int J Chron Obstruct Pulmon Dis. 2023 Apr 19;18:643-659. doi: 10.2147/COPD.S405498.

High-resolution line-scan Brillouin microscopy for live imaging of mechanical properties during embryo development. Bevilacqua C, Gomez JM, Fiuza UM, Chan CJ, Wang L, Hambura S, Eguren M, Ellenberg J, Diz-Muñoz A, Leptin M, Prevedel R. Nat Methods. 2023 May;20(5):755-760. doi: 10.1038/s41592-023-01822-1.

Impact of Total Ischemic Time and Disease Severity Class on Graft Function after Bilateral Lung Transplantation. Aburahma K, de Manna ND, Boethig D, Franz M, Iablonskii P, Heise EL, Bobylev D, Avsar M, Greer M, Schwerk N, Sommer W, Welte T, Haverich A, Warnecke G, Kuehn C, Salman J, Ius F. Eur J Cardiothorac Surg. 2023 May 12:ezad196. doi: 10.1093/ejcts/ezad196.

Low level of antioxidant capacity biomarkers but not target overexpression predicts vulnerability to ROS-inducing drugs. Samarin J, Fabrowski P, Kurilov R, Nuskova H, Hummel-Eisenbeiss J, Pink H, Li N, Weru V, Alborzinia H, Yildiz U, Grob L, Taubert M, Czech M, Morgen M, Brandstädter C, Becker K, Mao L, Jayavelu AK, Goncalves A, Uhrig U, Seiler J, Lyu Y, Diederichs S, Klingmüller U, Muckenthaler M, Kopp-Schneider A, Teleman A, Miller AK, Gunkel N. Redox Biol. 2023 Jun;62:102639. doi: 10.1016/j.redox.2023.102639.

Minimal clinically important difference for impulse oscillometry in adults with asthma. Abdo M, Kirsten AM, von Mutius E, Kopp M, Hansen G, Rabe KF, Watz H, Trinkmann F, Bahmer T; ALLIANCE study group. Eur Respir J. 2023 May 5;61(5):2201793. doi: 10.1183/13993003.01793-2022.

Quantitative CT analysis of lung parenchyma to improve malignancy risk estimation in incidental pulmonary nodules. Peters AA, Weinheimer O, von Stackelberg O, Kroschke J, Piskorski L, Debic M, Schlamp K, Welzel L, Pohl M, Christe A, Ebner L, Kauczor HU, Heußel CP, Wielpütz MO. Eur Radiol. 2023 Jun;33(6):3908-3917. doi: 10.1007/s00330-022-09334-w.

Rationale and Design of the Phase II ANTELOPE Study of Atezolizumab, Carboplatin and nab-Paclitaxel vs. Pembrolizumab, Platinum and Pemetrexed in TTF-1 Negative, Metastatic Lung Adenocarcinoma (AIO-TRK-0122). Frost N, Bleckmann A, Griesinger F, Grohé C, Janning M, Kollmeier J, Reinmuth N, Sebastian M, Thomas M, Reck M. Clin Lung Cancer. 2023 Apr 23:S1525-7304(23)00076-1. doi: 10.1016/j.cllc.2023.04.009.

Severe tracheal tear - an alternative extracorporeal membrane oxygenation indication. Buschulte K, Kahn N, Schmidt W, Reinhardt L. Perfusion. 2023 May 9:2676591231175983. doi: 10.1177/02676591231175983.

Supporting Biomarker-Driven Therapies in Oncology: A Genomic Testing Cost Calculator. Stenzinger A, Cuffel B, Paracha N, Vail E, Garcia-Foncillas J, Goodman C, Lassen U, Vassal G, Sullivan SD. Oncologist. 2023 May 8;28(5):e242-e253. doi: 10.1093/oncolo/oyad005.

Ziritaxestat, a Novel Autotaxin Inhibitor, and Lung Function in Idiopathic Pulmonary Fibrosis: The ISABELA 1 and 2 Randomized Clinical Trials. Maher TM, Ford P, Brown KK, Costabel U, Cottin V, Danoff SK, Groenveld I, Helmer E, Jenkins RG, Milner J, Molenberghs G, Penninckx B, Randall MJ, Van Den Blink B, Fieuw A, Vandenrijn C, Rocak S, Seghers I, Shao L, Taneja A, Jentsch G, Watkins TR, Wuyts WA, Kreuter M, Verbruggen N, Prasad N, Wijsenbeek MS; ISABELA 1 and 2 Investigators. JAMA. 2023 May 9;329(18):1567-1578. doi: 10.1001/jama.2023.5355.

Week 19 (8.05 - 14.05)

Anhaltende Belastungsdyspnoe nach Corona-Erkrankung. Trudzinski F. Pneumo News. 2023;15(2):25-26. doi: 10.1007/s15033-023-3488-2.

High-resolution transcriptomic and epigenetic profiling identifies novel regulators of COPD. Schwartz U, Llamazares Prada M, Pohl ST, Richter M, Tamas R, Schuler M, Keller C, Mijosek V, Muley T, Schneider MA, Quast K, Hey J, Heußel CP, Warth A, Winter H, Serçin Ö, Karmouty-Quintana H, Jyothula SS, Patel MK, Herth F, Koch I, Petrosino G, Titimeaua A, Mardin BR, Weichenhan D, Jurkowski TP, Imbusch CD, Brors B, Benes V, Jung B, Wyatt D, Stahl HF, Plass C, Jurkowska RZ. EMBO J. 2023 May 5:e111272. doi: 10.15252/embj.2022111272.

Indirect comparison of mobocertinib and real-world therapies for pre-treated non-small cell lung cancer with EGFR exon 20 insertion mutations. Christopoulos P, Prawitz T, Hong JL, Lin HM, Hernandez L, Jin S, Tan M, Proskorovsky I, Lin J, Zhang P, Patel JD, Ou SI, Thomas M, Stenzinger A. Lung Cancer. 2023 May;179:107191. doi: 10.1016/j.lungcan.2023.107191.

Longitudinal Magnetic Resonance Imaging Detects Onset and Progression of Chronic Rhinosinusitis from Infancy to School Age in Cystic Fibrosis. Wucherpfennig L, Wuennemann F, Eichinger M, Schmitt N, Seitz A, Baumann I, Stahl M, Graeber SY, Chung J, Schenk JP, Alrajab A, Kauczor HU, Mall MA, Sommerburg O, Wielpütz MO. Ann Am Thorac Soc. 2023 May;20(5):687-697. doi: 10.1513/AnnalsATS.202209-763OC.

Radiotheranostics in oncology: Making precision medicine possible. Aboagye EO, Barwick TD, Haberkorn U. CA Cancer J Clin. 2023 May-Jun;73(3):255-274. doi: 10.3322/caac.21768.

Spatial profiling of the microenvironment reveals low intratumoral heterogeneity and STK11-associated immune evasion in therapy-naïve lung adenocarcinomas. Goldschmid H, Kluck K, Ball M, Kirchner M, Allgäuer M, Winter H, Herth F, Heußel CP, Pullamsetti SS, Savai R, Yong TTK, Schirmacher P, Peters S, Thomas M, Christopoulos P, Budczies J, Stenzinger A, Kazdal D. Lung Cancer. 2023 Apr 23;180:107212. doi: 10.1016/j.lungcan.2023.107212.

Week 18 (1.05 - 7.05)

Comparison of the sensitivity of different criteria to select lung cancer patients for screening in a cohort of German patients. Walter J, Kauffmann-Guerrero D, Muley T, Reck M, Fuge J, Günther A, Majeed RW, Savai R, Koch I, Dinkel J, Schneider C, Senghas K, Kobinger S, Manapov F, Thomas M, Kahnert K, Winter H, Behr J, Tammemägi M, Tufman A. Cancer Med. 2023 Apr;12(7):8880-8896. doi: 10.1002/cam4.5638.

Identification of Adult Patients With Classical Dyskeratosis Congenita or Cryptic Telomere Biology Disorder by Telomere Length Screening Using Age-modified Criteria. Tometten M, Kirschner M, Meyer R, Begemann M, Halfmeyer I, Vieri M, Kricheldorf K, Maurer A, Platzbecker U, Radsak M, Schafhausen P, Corbacioglu S, Höchsmann B, Matthias Wilk C, Hinze C, Chromik J, Heuser M, Kreuter M, Koschmieder S, Panse J, Isfort S, Kurth I, Brümmendorf TH, Beier F. Hemasphere. 2023 Apr 20;7(5):e874. doi: 10.1097/HS9.0000000000000874.

Implementation of a spontaneous awakening/spontaneous breathing trial protocol in a surgical intensive care unit: a before and after study. Desantis M, Lichtenstern C, Hagenlocher JP, Bruckner T, Weigand MA, Kalenka A, Fiedler MO. Minerva Anestesiol. 2023 Apr;89(4):306-315. doi: 10.23736/S0375-9393.22.16806-9.

Integrated circulating tumour DNA and cytokine analysis for therapy monitoring of ALK-rearranged lung adenocarcinoma. Angeles AK, Janke F, Daum AK, Reck M, Schneider MA, Thomas M, Christopoulos P, Sültmann H. Br J Cancer. 2023 Apr 29. doi: 10.1038/s41416-023-02284-0.

Long-term effects of lumacaftor/ivacaftor on paranasal sinus abnormalities in children with cystic fibrosis detected with magnetic resonance imaging. Wucherpfennig L, Wuennemann F, Eichinger M, Seitz A, Baumann I, Stahl M, Graeber SY, Zhao S, Chung J, Schenk JP, Alrajab A, Kauczor HU, Mall MA, Sommerburg O, Wielpütz MO. Front Pharmacol. 2023 Apr 10;14:1161891. doi: 10.3389/fphar.2023.1161891.

Lungs From Donors ≥70 Years of Age for Transplantation-Do Long-Term Outcomes Justify Their Use? Sommer W, Franz M, Aburahma K, Saipbaev A, Flöthmann K, Yablonski P, Avsar M, Tudorache I, Greer M, Haverich A, Welte T, Kuehn C, Salman J, Warnecke G, Ius F. Transpl Int. 2023 Apr 13;36:11071. doi: 10.3389/ti.2023.11071.

MRI Compared with Low-Dose CT for Incidental Lung Nodule Detection in COPD: A Multicenter Trial. Li Q, Zhu L, von Stackelberg O, Triphan SMF, Biederer J, Weinheimer O, Eichinger M, Vogelmeier CF, Jörres RA, Kauczor HU, Heußel CP, Jobst BJ, Wielpütz MO; COSYCONET Study Group. Radiol Cardiothorac Imaging. 2023 Apr 27;5(2):e220176. doi: 10.1148/ryct.220176.

Trends in COVID-19-associated mortality in patients with pulmonary hypertension: a COMPERA analysis. Schmidt KH, Milger K, Pausch C, Huscher D, Pittrow D, Grünig E, Staehler G, Gall H, Distler O, Skowasch D, Halank M, Wilkens H, Held M, Klose H, Hoeper MM. Eur Respir J. 2023 Apr 27;61(4):2202440. doi: 10.1183/13993003.02440-2022.

Upfront and Repeated Stereotactic Radiosurgery in Patients With Brain Metastases From NSCLC. Krämer AS, Adeberg S, Kronsteiner D, König L, Schunn F, Bozorgmehr F, Christopoulos P, Eichkorn T, Schiele A, Hahnemann L, Rieken S, Debus J, Shafie RAE. Clin Lung Cancer. 2023 May;24(3):269-277. doi: 10.1016/j.cllc.2023.01.002.

Woche 17 (24.04 - 30.04)

Co-mutations and KRAS G12C inhibitor efficacy in advanced NSCLC. Negrao MV, Araujo HA, Lamberti G, Cooper AJ, Akhave NS, Zhou T, Delasos L, Hicks JK, Aldea M, Minuti G, Hines J, Aredo JV, Dennis MJ, Chakrabarti T, Scott SC, Bironzo P, Scheffler M, Christopoulos P, Stenzinger A, Riess JW, Kim SY, Goldberg SB, Li M, Wang Q, Qing Y, Ni Y, Do MT, Lee R, Ricciuti B, Alessi JV, Wang J, Resuli B, Landi L, Tseng SC, Nishino M, Digumarthy SR, Rinsurongkawong W, Rinsurongkawong V, Vaporciyan AA, Blumenschein GR, Zhang J, Owen DH, Blakely CM, Mountzios G, Shu CA, Bestvina CM, Garassino MC, Marrone KA, Gray JE, Patel SP, Cummings AL, Wakelee HA, Wolf J, Scagliotti GV, Cappuzzo F, Barlesi F, Patil PD, Drusbosky L, Gibbons DL, Meric-Bernstam F, Lee JJ, Heymach JV, Hong DS, Heist RS, Awad MM, Skoulidis F.Cancer Discov. 2023 Apr 17:CD-22-1420. doi: 10.1158/2159-8290.CD-22-1420.

Editorial: Systemic immune dysregulation in malignant disease: Insights, monitoring and therapeutic exploitation. Christopoulos P, Gaipl US. Front Oncol. 2023 Apr 3;13:1182081. doi: 10.3389/fonc.2023.1182081.

ERS International Congress 2022: highlights from the Interstitial Lung Diseases Assembly. Karampitsakos T, Diep PP, Loth DW, Nadeem I, Khurtsidze E, Wijsenbeek MS, Wuyts WA, Bargagli E, Froidure A, Spagnolo P, Veltkamp M, Molina-Molina M, McCarthy C, Antoniou KM, Kreuter M, Moor CC. ERJ Open Res. 2023 Apr 17;9(2):00584-2022. doi: 10.1183/23120541.00584-2022.

Reporting Standards for Diagnostic Testing: Guidance for Authors From Editors of Respiratory, Sleep, and Critical Care Journals. Ost DE, Feller-Kopman DJ, Gonzalez A, Grosu HB, Herth F, Mazzone P, Park JES, Porcel JM, Shojaee S, Tsiligianni I, Vachani A, Bernstein J, Branson R, Flume PA, Akdis CA, Kolb M, Portela EB, Smyth A. J Bronchology Interv Pulmonol. 2023 Apr 10. doi: 10.1097/LBR.0000000000000920.

Safety and effectiveness of standardized exercise training in patients with pulmonary hypertension associated with heart failure with preserved ejection fraction (TRAIN-HFpEF-PH): study protocol for a randomized controlled multicenter trial. Palevičiūtė E, Čelutkienė J, Šimbelytė T, Gumbienė L, Jurevičienė E, Zakarkaitė D, Čėsna S, Eichstaedt CA, Benjamin N, Grünig E. Trials. 2023 Apr 19;24(1):281. doi: 10.1186/s13063-023-07297-x.

Week 16 (17.04 - 23.04)

Homogenous TP53mut-associated tumor biology across mutation and cancer types revealed by transcriptome analysis. Romanovsky E, Kluck K, Ourailidis I, Menzel M, Beck S, Ball M, Kazdal D, Christopoulos P, Schirmacher P, Stiewe T, Stenzinger A, Budczies J. Cell Death Discov. 2023 Apr 14;9(1):126. doi: 10.1038/s41420-023-01413-1.

How Informed Are German Patients with Pulmonary Sarcoidosis about Their Disease? Buschulte K, Höger P, Ganter C, Wijsenbeek M, Kahn N, Kriegsmann K, Wilkens FM, Polke M, El-Hadi S, Lederer C, Herth FJ, Kreuter M. Respiration. 2023 Apr 13:1-9. doi: 10.1159/000529890.

Indirect comparison of mobocertinib and real-world therapies for pre-treated non-small cell lung cancer with EGFR exon 20 insertion mutations. Christopoulos P, Prawitz T, Hong JL, Lin HM, Hernandez L, Jin S, Tan M, Proskorovsky I, Lin J, Zhang P, Patel JD, Ou SI, Thomas M, Stenzinger A. Lung Cancer. 2023 Apr 8;179:107191. doi: 10.1016/j.lungcan.2023.107191.

Survival-Adjusted FEV1 and BMI Percentiles for Patients with Cystic Fibrosis before the Era of Triple CFTR Modulator Therapy in Germany. Dittrich AS, Dumke M, Kapl F, Schneider P, Wege S, Gräber S, Stahl M, Herth FJ, Naehrlich L, Mall MA, Sommburg O; German CF Registry. Respiration. 2023 Apr 14:1-10. doi: 10.1159/000529524.

Transformation of ALK-positive NSCLC to SCLC after alectinib resistance and response to combined atezolizumab: a case report. Xia G, Huang J, Ni J, Song M, Zhang J, Hofman P, Christopoulos P, Grenda A, Huang M. Transl Lung Cancer Res. 2023 Mar 31;12(3):637-646. doi: 10.21037/tlcr-23-154.

Week 15 (10.04 - 16.04)

Characterization of three new SERPINA1 variants PiQ0_{Heidelberg II}, PiQ0_{Heidelberg III} and PiQ0_{Heidelberg IV} in patients with severe alpha-1 antitrypsin deficiency. Höger P, Veith M, Greulich T, Limen E, Brock J, Schlamp K, Buschulte K, Presotto MA, Schäfer JC, Herth F, Trudzinski FC. Respir Med Case Rep. 2023 Mar 13;43:101838. doi: 10.1016/j.rmcr.2023.101838.

Chronic Airways Assessment Test: psychometric properties in patients with asthma and/or COPD. Tomaszewski EL, Atkinson MJ, Janson C, Karlsson N, Make B, Price D, Reddel HK, Vogelmeier CF, Müllerová H, Jones PW; NOVELTY Scientific Community; and the NOVELTY study investigators. Respir Res. 2023 Apr 8;24(1):106. doi: 10.1186/s12931-023-02394-6.

Immunomodulatory treatment in unclassifiable interstitial lung disease: A retrospective study of treatment response. Hyldgaard C, Torrisi S, Kronborg Brix-White S, Prior TS, Ganter C, Bendstrup E, Kreuter M. Respirology. 2023 Apr;28(4):373-379. doi: 10.1111/resp.14409.

Magnetic resonance imaging detects onset and association with lung disease severity of bronchial artery dilatation in cystic fibrosis. Leutz-Schmidt P, Optazaite DE, Sommerburg O, Eichinger M, Wege S, Steinke E, Graeber SY, Puderbach MU, Schenk JP, Alrajab A, Triphan SMF, Kauczor HU, Stahl M, Mall MA, Wielpütz MO. ERJ Open Res. 2023 Mar 27;9(2):00473-2022. doi: 10.1183/23120541.00473-2022.

Myeloid-specific fatty acid transport protein 4 deficiency induces a sex-dimorphic susceptibility for nonalcoholic steatohepatitis in mice fed a high-fat, high-cholesterol diet. Göcebe D, Jansakun C, Zhang Y, Staffer S, Tuma-Kellner S, Altamura S, Muckenthaler MU, Merle U, Herrmann T, Chamulitrat W. Am J Physiol Gastrointest Liver Physiol. 2023 May 1;324(5):G389-G403. doi: 10.1152/ajpgi.00181.2022.

Week 14 (3.04 - 9.04)

[Consensus guideline on the interdisciplinary diagnosis of interstitial lung diseases]. Kreuter M, Behr J, Bonella F, Costabel U, Gerber A, Hamer OW, Heussel CP, Jonigk D, Krause A, Koschel D, Leuschner G, Markart P, Nowak D, Pfeifer M, Prasse A, Wälscher J, Winter H, Kabitz HJ. Pneumologie. 2023 Mar 28. doi: 10.1055/a-2017-8971.

Imaging the right atrium in pulmonary hypertension: A systematic review and meta-analysis. Richter MJ, Fortuni F, Alenezi F, D'Alto M, Badagliacca R, Brunner NW, van Dijk AP, Douschan P, Gall H, Ghio S, Giudice FL, Grünig E, Haddad F, Howard L, Rajagopal S, Stens N, Stolfo D, Thijssen DHJ, Vizza CD, Zamanian RT, Zhong L, Seeger W, Ghofrani HA, Tello K. J Heart Lung Transplant. 2023 Apr;42(4):433-446. doi: 10.1016/j.healun.2022.11.007.

Prevention of invasive ventilation (PRiVENT)-a prospective, mixed-methods interventional, multicentre study with a parallel comparison group: study protocol. Michels JD, Meis J, Sturm N, Bornitz F, von Schumann S, Weis A, Neetz B, Bentner M, Forstner J, Litke N, Wensing M, Erdmann S, Grobe T, Frerk T, Kempa A, Neurohr C, Schneider A, Müller M, Herth FJF, Szecsenyi J, Trudzinski FC; PRiVENT-Study Group. BMC Health Serv Res. 2023 Mar 30;23(1):305. doi: 10.1186/s12913-023-09283-0.

Week 13 (27.03 - 02.04)

Effects of Lumacaftor/Ivacaftor on Cystic Fibrosis Disease Progression in Children 2 through 5 Years of Age Homozygous for F508del-CFTR: A Phase 2 Placebo-controlled Clinical Trial. Stahl M, Roehmel J, Eichinger M, Doellinger F, Naehrlich L, Kopp MV, Dittrich AM, Lee C, Sommerburg O, Tian S, Xu T, Wu P, Joshi A, Ray P, Duncan ME, Wielpütz MO, Mall MA. Ann Am Thorac Soc. 2023 Mar 21. doi: 10.1513/AnnalsATS.202208-684OC.

High resolution propagation-based lung imaging at clinically relevant X-ray dose levels. Albers J, Wagner WL, Fiedler MO, Rothermel A, Wünnemann F, Di Lillo F, Dreossi D, Sodini N, Baratella E, Confalonieri M, Arfelli F, Kalenka A, Lotz J, Biederer J, Wielpütz MO, Kauczor HU, Alves F, Tromba G, Dullin C. Sci Rep. 2023 Mar 23;13(1):4788. doi: 10.1038/s41598-023-30870-y.

Reproducibility of pulmonary magnetic resonance angiography in adults with muco-obstructive pulmonary disease. Wucherpfennig L, Triphan SM, Weinheimer O, Eichinger M, Wege S, Eberhardt R, Puderbach MU, Kauczor HU, Heussel CP, Heussel G, Wielpütz MO. Acta Radiol. 2023 Mar;64(3):1038-1046. doi: 10.1177/02841851221111486.

To fly or not to fly: Stereotactic MR-guided adaptive radiotherapy effectively treats ultracentral lung tumors with favorable long-term outcomes. Regnery S, Katsigiannopulos E, Hoegen P, Weykamp F, Sandrini E, Held T, Deng M, Eichkorn T, Buchele C, Rippke C, Renkamp CK, König L, Lang K, Thomas M, Winter H, Adeberg S, Klüter S, Debus J, Hörner-Rieber J. Lung Cancer. 2023 Mar 21;179:107175. doi: 10.1016/j.lungcan.2023.03.011.

Week 12 (20.03 - 26.03)

Can we cure metastatic EGFR-mutated lung cancer today? Christopoulos P. Transl Cancer Res. 2023 Feb 28;12(2):209-212. doi: 10.21037/tcr-22-2926.

Feasibility and Safety of Endosonography-Guided Transvascular Needle Aspiration in the Diagnosis of Thoracic and Abdominal Lesions: A Meta-Analysis. Yang H, Yang W, Zhang X, Zhang Q, Wang Z, Chen C, Herth FJF. Respiration. 2023;102(3):220-226. doi: 10.1159/000528529.

Safety and Feasibility of a Novel Externally Cooled Bronchoscopic Radiofrequency Ablation Catheter for Ablation of Peripheral Lung Tumours: A First-In-Human Dose Escalation Study. Steinfort DP, Antippa P, Rangamuwa K, Irving LB, Christie M, Chan E, Marinelli B, Wang J, Yoneda KY, Raina S, Herth FJ. Respiration. 2023;102(3):211-219. doi: 10.1159/000529167.

[SARS-CoV-2-Infection and Interstitial Lung Disease: Position paper of the German Respiratory Society]. Behr J, Berger M, Blum TG, Bonella F, Dinkel J, Gläser S, Hagmeyer L, Kneidinger N, Koschel D, Prasse A, Slevogt H, Stacher-Priehse E, Woehrle H, Kreuter M. Pneumologie. 2023 Mar;77(3):143-157. doi: 10.1055/a-2007-9845.

Week 11 (13.03 - 19.03)

Assessment of the EarlyCDT-Lung test as an early biomarker of lung cancer in ever-smokers: A retrospective nested case-control study in two prospective cohorts. Wu WY, Haider Z, Feng X, Heath AK, Tjønneland A, Agudo A, Masala G, Robbins HA, Huerta JM, Guevara M, Schulze MB, Rodriguez-Barranco M, Vineis P, Tumino R, Kaaks R, Fortner RT, Sieri S, Panico S, Nøst TH, Sandanger TM, Braaten T, Johansson M, Melin B, Johansson M. Int J Cancer. 2023 May 1;152(9):2002-2010. doi: 10.1002

Endobronchial ultrasound-guided cryobiopsy-when it is indicated? - Authors' reply. Zhang AM, Huang ZS, Fan Y, Herth FJ. Lancet Respir Med. 2023 Mar;11(3):e24. doi: 10.1016/S2213-2600(22)00485-4.

Hypochromic red cells as a prognostic indicator of survival among patients with systemic sclerosis screened for pulmonary hypertension. Xanthouli P, Gordjani O, Benjamin N, Harutyunova S, Egenlauf B, Marra AM, Haas S, Milde N, Blank N, Lorenz HM, Fiehn C, Ulrich S, Distler O, Grünig E, Eichstaedt CA. Arthritis Res Ther.

Myeloid-specific FATP4 deficiency induces a sex-dimorphic susceptibility for NASH in mice fed with high-fat/high-cholesterol diet. Göcebe D, Jansakun C, Zhang Y, Staffer S, Tuma-Kellner S, Altamura S, Muckenthaler MU, Merle U, Herrmann T, Chamulitrat W. Am J Physiol Gastrointest Liver Physiol. 2023 Mar 7. doi: 10.1152/ajpgi.00181.2022.

Phase 3 Trial of Sotatercept for Treatment of Pulmonary Arterial Hypertension. Hoeper MM, Badesch DB, Ghofrani HA, Gibbs JSR, Gomberg-Maitland M, McLaughlin VV, Preston IR, Souza R, Waxman AB, Grünig E, Kopeć G, Meyer G, Olsson KM, Rosenkranz S, Xu Y, Miller B, Fowler M, Butler J, Koglin J, de Oliveira Pena J, Humbert M; STELLAR Trial Investigators. N Engl J Med. 2023 Mar 6. doi: 10.1056/NEJMoa2213558.

Quantification of airway wall contrast enhancement on virtual monoenergetic images from spectral computed tomography. Bodenberger AL, Konietzke P, Weinheimer O, Wagner WL, Stiller W, Weber TF, Heussel CP, Kauczor HU, Wielpütz MO. Eur Radiol. 2023 Mar 9. doi: 10.1007/s00330-023-09514-2.

Transbronchial needle aspiration combined with cryobiopsy in the diagnosis of mediastinal diseases: a multicentre, open-label, randomised trial. Fan Y, Zhang AM, Wu XL, Huang ZS, Kontogianni K, Sun K, Fu WL, Wu N, Kuebler WM, Herth FJF. Lancet Respir Med. 2023 Mar;11(3):256-264. doi: 10.1016/S2213-2600(22)00392-7.

Weight loss and outcomes in subjects with progressive pulmonary fibrosis: data from the INBUILD trial. Kreuter M, Bendstrup E, Jouneau S, Maher TM, Inoue Y, Miede C, Lievens D, Crestani B. Respir Res. 2023 Mar 9;24(1):71. doi: 10.1186/s12931-023-02371-z.

"Will I change nodule management recommendations if I change my CAD system?"-impact of volumetric deviation between different CAD systems on lesion management. Peters AA, Christe A, von Stackelberg O, Pohl M, Kauczor HU, Heußel CP, Wielpütz MO, Ebner L. Eur Radiol. 2023 Mar 10. doi: 10.1007/s00330-023-09525-z.

Week 10 (6.03 - 12.03)

Genetic counselling and testing in pulmonary arterial hypertension: a consensus statement on behalf of the International Consortium for Genetic Studies in PAH. Eichstaedt CA, Belge C, Chung WK, Gräf S, Grünig E, Montani D, Quarck R, Tenorio-Castano JA, Soubrier F, Trembath RC, Morrell NW; for PAH-ICON associated with the PVRI. Eur Respir J. 2023 Feb 23;61(2):2201471. doi: 10.1183/13993003.01471-2022

HDAC6 score: to treat or not to treat? Hey J, Llamazares Prada M, Plass C. Nat Cancer. 2023 Feb;4(2):156-158. doi: 10.1038/s43018-022-00494-8

[Increasingly treatable: Pulmonary Fibrosis]. Polke M, Herth FJF. MMW Fortschr Med. 2023 Feb;165(Suppl 1):36-38. doi: 10.1007/s15006-023-2331-3.

Real-world data for precision cancer medicine - a European perspective. Christopoulos P, Schlenk R, Kazdal D, Blasi M, Lennerz J, Shah R, Budczies J, Malek N, Fröhling S, Rosenquist R, Schirmacher P, Bozorgmehr F, Kuon J, Reck M, Thomas M, Stenzinger A. Genes Chromosomes Cancer. 2023 Feb 28. doi: 10.1002/gcc.23135.

Simultaneous assessment of heart and lungs with gated high-pitch ultra-low dose chest CT using artificial intelligence-based calcium scoring. Andre F, Seitz S, Fortner P, Allmendinger T, Sommer A, Brado M, Sokiranski R, Fink J, Kauczor HU, Heussel CP, Herth F, Frey N, Görich J, Buss SJ. Eur J Radiol Open. 2023 Feb 15;10:100481. doi: 10.1016/j.ejro.2023.100481.

Week 9 (27.02 - 5.03)

Body shape phenotypes of multiple anthropometric traits and cancer risk: a multi-national cohort study. Sedlmeier AM, Viallon V, Ferrari P, Peruchet-Noray L, Fontvieille E, Amadou A, Seyed Khoei N, Weber A, Baurecht H, Heath AK, Tsilidis K, Kaaks R, Katzke V, Inan-Eroglu E, Schulze MB, Overvad K, Bonet C, Ubago-Guisado E, Chirlaque MD, Ardanaz E, Perez-Cornago A, Pala V, Tumino R, Sacerdote C, Pasanisi F, Borch KB, Rylander C, Weiderpass E, Gunter MJ, Fervers B, Leitzmann MF, Freisling H. Br J Cancer. 2023 Feb;128(4):594-605. doi: 10.1038/s41416-022-02071-3.

Effect of nintedanib in patients with systemic sclerosis-associated interstitial lung disease and risk factors for rapid progression. Khanna D, Maher TM, Volkmann ER, Allanore Y, Smith V, Assassi S, Kreuter M, Hoffmann-Vold AM, Kuwana M, Stock C, Alves M, Sambevski S, Denton CP. RMD Open. 2023 Feb;9(1):e002859. doi: 10.1136/rmdopen-2022-002859

[Interstitial lung diseases : Classification, differential diagnosis and treatment approaches in a heterogeneous group of chronic lung disorders]. Lederer C, Buschulte K, Hellmich B, Heußel CP, Kriegsmann M, Polke M, Kreuter M. Inn Med (Heidelb). 2023 Mar;64(3):247-259. doi: 10.1007/s00108-023-01476-3.

MDCT-based longitudinal automated airway and air trapping analysis in school-age children with mild cystic fibrosis lung disease. Weinheimer O, Konietzke P, Wagner WL, Weber D, Newman B, Galbán CJ, Kauczor HU, Mall MA, Robinson TE, Wielpütz MO. Front Pediatr. 2023 Feb 2;11:1068103. doi: 10.3389/fped.2023.1068103.

Upfront and Repeated Stereotactic Radiosurgery in Patients With Brain Metastases From NSCLC. Krämer AS, Adeberg S, Kronsteiner D, König L, Schunn F, Bozorgmehr F, Christopoulos P, Eichkorn T, Schiele A, Hahnemann L, Rieken S, Debus J, Shafie RAE. Clin Lung Cancer. 2023 Jan 21:S1525-7304(23)00006-2. doi: 10.1016/j.cllc.2023.01.002.

Week 8 (20.02 - 26.02)

Clathrin-Mediated Albumin Clearance in Alveolar Epithelial Cells of Murine Precision-Cut Lung Slices. Kryvenko V, Alberro-Brage A, Fysikopoulos A, Wessendorf M, Tello K, Morty RE, Herold S, Seeger W, Samakovlis C, Vadász I. Int J Mol Sci. 2023 Jan 31;24(3):2644. doi: 10.3390/ijms24032644.

German newborn screening for Cystic fibrosis: Parental perspectives and suggestions for improvements. Gapp S, Garbade SF, Feyh P, Brockow I, Nennstiel U, Hoffmann GF, Sommerburg O, Gramer G. Pediatr Pulmonol. 2023 Mar;58(3):844-852. doi: 10.1002/ppul.26263.

Molecular Epidemiology and Treatment Patterns of Patients With EGFR Exon 20-Mutant NSCLC in the Precision Oncology Era: The European EXOTIC Registry. Mountzios G, Planchard D, Metro G, Tsiouda D, Prelaj A, Lampaki S, Shalata W, Riudavets M, Christopoulos P, Girard N, Albarrán-Artahona V, Garcia Campelo R, Samitas K, Banna GL, Boukovinas I, Agbarya A, Koumarianou A, Perdikouri EI, Kosmidis P, Linardou H, Mauri D, Mavroudis D, Athanasiadis I, Kalofonos H, Xenidis N, Korantzis I, Ardavanis A, Rallis G, Bottiglieri A, Efthymiadis K, Oikonomopoulos G, Kokkalis A, Saloustros E, Tsoukalas N, Bartzi D, Economopoulou P, Psyrri A, Reck M, Lo Russo G. JTO Clin Res Rep. 2022 Nov 20;4(1):100433. doi: 10.1016/j.jtocrr.2022.100433.

[Pharmacological treatment of idiopathic pulmonary fibrosis (update) and progressive pulmonary fibrosis - S2k Guideline of the German Respiratory Society]. Behr J, Bonella F, Frye BC, Günther A, Hagmeyer L, Henes J, Klemm P, Koschel D, Kreuter M, Leuschner G, Nowak D, Prasse A, Quadder B, Sitter H, Costabel U. Pneumologie. 2023 Feb;77(2):94-119. doi: 10.1055/a-1983-6796.

Screening versus multidimensional assessment of symptoms and psychosocial distress in cancer patients from the time of incurability. Solar S, Wieditz J, Lordick F, Mehnert-Theuerkauf A, Oechsle K, van Oorschot B, Thomas M, Asendorf T, Nauck F, Alt-Epping B. Front Oncol. 2023 Jan 26;13:1002499. doi: 10.3389/fonc.2023.1002499.

Time-controlled adaptive ventilation in patients with ARDS-lack of protocol adherence: a systematic review. Katzenschlager S, Simon CM, Rehn P, Grilli M, Fiedler MO, Müller M, Weigand MA, Neetz B. Crit Care. 2023 Feb 10;27(1):57. doi: 10.1186/s13054-023-04340-w.

[What have we learned from the German COPD cohort COSYCONET and where do we go from here?]. Kahnert K, Fischer C, Alter P, Trudzinski F, Welte T, Behr J, Herth F, Kauczor HU, Bals R, Watz H, Rabe K, Söhler S, Kokot I, Vogelmeier C, Jörres R. Pneumologie. 2023 Feb;77(2):81-93. doi: 10.1055/a-1966-0848.

Week 7 (13.02 - 19.02)

Bronchoscopy and the Risk of SARS-CoV-2 Infection for the Staff. Brock J, Trinkmann F, Kontogianni K, Herth J, Herth FJ. Respiration. 2023 Feb 7:1-3. doi: 10.1159/000529195.

Impact of lung function and baseline clinical characteristics on patient-reported outcome measures in systemic sclerosis-associated interstitial lung disease. Kreuter M, Hoffmann-Vold AM, Matucci-Cerinic M, Saketkoo LA, Highland KB, Wilson H, Alves M, Erhardt E, Schoof N, Maher TM. Rheumatology (Oxford). 2023 Feb 6;62(SI):SI43-SI53. doi: 10.1093/rheumatology/keac325.

Investigating significant health trends in progressive fibrosing interstitial lung disease (INSIGHTS-ILD): rationale, aims and design of a nationwide prospective registry. Behr J, Bonella F, Günther A, Koschel D, Prasse A, Pittrow D, Klotsche J, Kreuter M; INSIGHTS-ILD Study Group. BMC Pulm Med. 2023 Feb 11;23(1):64. doi: 10.1186/s12890-023-02333-7.

Minimal Clinically Important Difference for Impulse Oscillometry in Adults with Asthma. Abdo M, Kirsten AM, von Mutius E, Kopp M, Hansen G, Rabe KF, Watz H, Trinkmann F, Bahmer T; ALLIANCE study group. Eur Respir J. 2023 Feb 9:2201793. doi: 10.1183/13993003.01793-2022.

MR imaging of the airways. Biederer J. Br J Radiol. 2023 Feb 8:20220630. doi: 10.1259/bjr.20220630.

Prognostic factors in nonsmall cell lung cancer: insights from the German CRISP registry. Metzenmacher M, Griesinger F, Hummel HD, Elender C, Schäfer H, de Wit M, Kaiser U, Kern J, Jänicke M, Spring L, Zacharias S, Kaiser-Osterhues A, Groth A, Hipper A, Zaun G, Dörfel S, Güldenzoph B, Müller L, Uhlig J, Thomas M, Sebastian M, Eberhardt WEE; CRISP Registry Group. Eur Respir J. 2023 Feb 2;61(2):2201336. doi: 10.1183/13993003.01336-2022. Print 2023 Feb.

The effect of exercise training and physiotherapy on left and right heart function in heart failure with preserved ejection fraction: a systematic literature review. Palevičiūtė E, Šimbelytė T, Eichstaedt CA, Benjamin N, Egenlauf B, Grünig E, Čelutkienė J. Heart Fail Rev. 2023 Jan;28(1):193-206. doi: 10.1007/s10741-022-10259-1.

The flare of care for rare: per aspera ad astra for rare lung diseases! Wijsenbeek M, Humbert M, Wagner T, Kreuter M. Eur Respir Rev. 2023 Feb 7;32(167):230006. doi: 10.1183/16000617.0006-2023.

The world of rare interstitial lung diseases. Buschulte K, Cottin V, Wijsenbeek M, Kreuter M, Diesler R. Eur Respir Rev. 2023 Feb 7;32(167):220161. doi: 10.1183/16000617.0161-2022.

Week 6 (6.02 - 12.02)

Bronchoscopic Measurement of Collateral Ventilation: State of the Art. Saccomanno J, Hübner RH, Witzenrath M, Doellinger F, Dittrich AS, Kontogianni K, Herth F, Brock JM. Respiration. 2023 Feb 2:1-12. doi: 10.1159/000528419.

Distribution and Detectability of EGFR Exon 20 Insertion Variants in Non-small Cell Lung Cancer. Ignatius Ou SH, Hong JL, Christopoulos P, Lin HM, Vincent S, Churchill EN, Soeda J, Kazdal D, Stenzinger A, Thomas M. J Thorac Oncol. 2023 Feb 2:S1556-0864(23)00095-3. doi: 10.1016/j.jtho.2023.01.086.

Gender-specific differences in COPD symptoms and their impact for the diagnosis of cardiac comorbidities. Trudzinski FC, Kellerer C, Jörres RA, Alter P, Lutter JI, Trinkmann F, Herth FJF, Frankenberger M, Watz H, Vogelmeier CF, Kauczor HU, Welte T, Behr J, Bals R, Kahnert K. Clin Res Cardiol. 2023 Feb;112(2):177-186. doi: 10.1007/s00392-021-01915-x.

Global hypomethylation in childhood asthma identified by genome-wide DNA-methylation sequencing preferentially affects enhancer regions. Thürmann L, Klös M, Mackowiak SD, Bieg M, Bauer T, Ishaque N, Messingschlager M, Herrmann C, Röder S, Bauer M, Schäuble S, Faessler E, Hahn U, Weichenhan D, Mücke O, Plass C, Borte M, von Mutius E, Stangl GI, Lauener R, Karvonen AM, Divaret-Chauveau A, Riedler J, Heinrich J, Standl M, von Berg A, Schaaf B, Herberth G, Kabesch M, Eils R, Trump S, Lehmann I. Allergy. 2023 Jan 27. doi: 10.1111/all.15658.

High-risk patients with locally advanced non-small cell lung cancer treated with stereotactic body radiation therapy to the peripheral primary combined with conventionally fractionated volumetric arc therapy to the mediastinal lymph nodes. Eichkorn T, Lischalk JW, Stüwe C, Tonndorf-Martini E, Schubert K, Dinges LA, Regnery S, Bozorgmehr F, König L, Christopoulos P, Hörner-Rieber J, Adeberg S, Herfarth K, Winter H, Thomas M, Rieken S, Debus J, El Shafie RA. Front Oncol. 2023 Jan 13;12:1035370. doi: 10.3389/fonc.2022.1035370.

Implementation of artificial intelligence in thoracic imaging-a what, how, and why guide from the European Society of Thoracic Imaging (ESTI). Gleeson F, Revel MP, Biederer J, Larici AR, Martini K, Frauenfelder T, Screaton N, Prosch H, Snoeckx A, Sverzellati N, Ghaye B, Parkar AP. Eur Radiol. 2023 Feb 2:1-10. doi: 10.1007/s00330-023-09409-2.

Oxygenated hemoglobin as prognostic marker among patients with systemic sclerosis screened for pulmonary hypertension. Xanthouli P, Gordjani O, Benjamin N, Trudzinski FC, Egenlauf B, Harutyunova S, Marra AM, Milde N, Nagel C, Blank N, Lorenz HM, Grünig E, Eichstaedt CA. Sci Rep. 2023 Feb 1;13(1):1839. doi: 10.1038/s41598-023-28608-x.

Standardized airway wall thickness Pi10 from routine CT scans of COPD patients as imaging biomarker for disease severity, lung function decline, and mortality. Kahnert K, Jörres RA, Kauczor HU, Alter P, Trudzinski FC, Herth F, Jobst B, Weinheimer O, Nauck S, Mertsch P, Kauffmann-Guerrero D, Behr J, Bals R, Watz H, Rabe KF, Welte T, Vogelmeier CF, Biederer J. Ther Adv Respir Dis. 2023 Jan-Dec;17:17534666221148663. doi: 10.1177/17534666221148663.

Static and Dynamic ⁶⁸Ga-FAPI PET/CT for the Detection of Malignant Transformation of Intraductal Papillary Mucinous Neoplasia of the Pancreas. Lang M, Spektor AM, Hielscher T, Hoppner J, Glatting FM, Bicu F, Hackert T, Heger U, Pausch T, Gutjahr E, Rathke H, Giesel FL, Kratochwil C, Tjaden C, Haberkorn U, Röhrich M. J Nucl Med. 2023 Feb;64(2):244-251. doi: 10.2967/jnumed.122.264361

Study protocol of an international patient-led registry in patients with pulmonary fibrosis using online home monitoring: I-FILE. Nakshbandi G, Moor CC, Antoniou K, Cottin V, Hoffmann-Vold AM, Koemans EA, Kreuter M, Molyneaux PL, Wuyts WA, Wijsenbeek MS. BMC Pulm Med. 2023 Feb 2;23(1):51. doi: 10.1186/s12890-023-02336-4.

Week 5 (30.01 - 5.02)

Anti-acid therapy in SSc-associated interstitial lung disease: long-term outcomes from the German Network for Systemic Sclerosis. Kreuter M, Bonella F, Blank N, Riemekasten G, Müller-Ladner U, Henes J, Siegert E, Günther C, Kötter I, Pfeiffer C, Schmalzing M, Zeidler G, Korsten P, Susok L, Juche A, Worm M, Jandova I, Ehrchen J, Sunderkötter C, Keyßer G, Ramming A, Schmeiser T, Kreuter A, Kuhr K, Lorenz HM, Moinzadeh P, Hunzelmann N. Rheumatology (Oxford). 2023 Jan 27:kead023. doi: 10.1093/rheumatology/kead023. Online ahead of print.

[Chronic cough]. Schellenberg M, Herth FJF. Inn Med (Heidelb). 2023 Jan 26. doi: 10.1007/s00108-022-01467-w. Online ahead of print.

Magnetic resonance imaging-based scoring of the diseased lung in the preterm infant with bronchopulmonary dysplasia: UNiforme Scoring of the disEAsed Lung in BPD (UNSEAL BPD). Förster K, Marchi H, Stöcklein S, Dietrich O, Ehrhardt H, Wielpütz MO, Flemmer AW, Schubert B, Mall MA, Ertl-Wagner B, Hilgendorff A. Am J Physiol Lung Cell Mol Physiol. 2023 Feb 1;324(2):L114-L122. doi: 10.1152/ajplung.00430.2021.

TRACK-CF prospective cohort study: Understanding early cystic fibrosis lung disease. Steinke E, Sommerburg O, Graeber SY, Joachim C, Labitzke C, Nissen G, Ricklefs I, Rudolf I, Kopp MV, Dittrich AM, Mall MA, Stahl M. Front Med (Lausanne). 2023 Jan 6;9:1034290. doi: 10.3389/fmed.2022.1034290. eCollection 2022.

Week 4 (23.01 - 29.01)

Impact of Chewing Bags, E-Cigarettes, and Combustible Cigarettes on Arterial Stiffness and Small Airway Function in Healthy Students. Hauck AS, Buchwald I, Watz H, Trinkmann F, Söling C, Rabenstein A, Ruether T, Mortensen K, Drömann D, Franzen KF. Toxics. 2023 Jan 14;11(1):77. doi: 10.3390/toxics11010077.

Tolerability, safety and survival in patients with severe pulmonary arterial hypertension treated with intravenous epoprostenol (Veletri^®): a prospective, 6-months, open label, observational, non-interventional study. Degering J, Egenlauf B, Harutyunova S, Benjamin N, Salkić A, Xanthouli P, Eichstaedt CA, Seeger R, Sitbon O, Grünig E. Respir Res. 2023 Jan 18;24(1):18. doi: 10.1186/s12931-022-02296-z.

Week 3 (16.01 - 22.01)

Pericentromeric satellite lncRNAs are induced in cancer-associated fibroblasts and regulate their functions in lung tumorigenesis. Enukashvily NI, Ponomartsev NV, Ketkar A, Suezov R, Chubar AV, Prjibelski AD, Shafranskaya DD, Elmshäuser S, Keber CU, Stefanova VN, Akopov AL, Klingmüller U, Pfefferle PI, Stiewe T, Lauth M, Brichkina AI. Cell Death Dis. 2023 Jan 12;14(1):19. doi: 10.1038/s41419-023-05553-1.

Alectinib as first-line treatment for advanced ALK-positive non-small cell lung cancer in the real-world setting: preliminary analysis in a Chinese cohort. Zou Z, Gu Y, Liang L, Hao X, Fan C, Xin T, Zhao S, Liu Z, Guo Y, Ma K, Li H, Zhang C, Shan L, Zhang Y, Dong G, Peng Y, Shen F, Song X, Christopoulos P, van der Wekken AJ, Okuda K, Ekman S, Xing P, Li J. Transl Lung Cancer Res. 2022 Dec;11(12):2495-2506. doi: 10.21037/tlcr-22-803.

Week 2 (9.01. - 15.01)

Computed tomographic airway morphology after targeted lung denervation treatment in COPD. Hartman JE, Herth FJF, Shah P, Pison C, Valipour A, Slebos DJ; AIRFLOW-2 Study Group. Respir Med. 2023 Jan;206:107059. doi: 10.1016/j.rmed.2022.107059. Epub 2022 Nov 26.

Imaging the right atrium in pulmonary hypertension: A systematic review and meta-analysis. Richter MJ, Fortuni F, Alenezi F, D'Alto M, Badagliacca R, Brunner NW, van Dijk AP, Douschan P, Gall H, Ghio S, Giudice FL, Grünig E, Haddad F, Howard L, Rajagopal S, Stens N, Stolfo D, Thijssen DHJ, Vizza CD, Zamanian RT, Zhong L, Seeger W, Ghofrani HA, Tello K. J Heart Lung Transplant. 2022 Dec 9:S1053-2498(22)02243-4. doi: 10.1016/j.healun.2022.11.007. Online ahead of print.

Serum Extracellular Vesicle-Derived microRNAs as Potential Biomarkers for Pleural Mesothelioma in a European Prospective Study. Casalone E, Birolo G, Pardini B, Allione A, Russo A, Catalano C, Mencoboni M, Ferrante D, Magnani C, Sculco M, Dianzani I, Grosso F, Mirabelli D, Filiberti RA, Rena O, Sacerdote C, Rodriguez-Barranco M, Smith-Byrne K, Panico S, Agnoli C, Johnson T, Kaaks R, Tumino R, Huerta JM, Riboli E, Heath AK, Trobajo-Sanmartín C, Schulze MB, Saieva C, Amiano P, Agudo A, Weiderpass E, Vineis P, Matullo G. Cancers (Basel). 2022 Dec 25;15(1):125. doi: 10.3390/cancers15010125.

Stent Evaluation for Expiratory Central Airway Collapse: Does the Type of Stent Really Matter? Majid A, Ospina-Delgado D, Ayala A, Gangadharan SP, Alape D, Buitrago D, Parikh MS, Wilson JL, Chee AC, Fernandez-Bussy S, Herth FJF, Kheir F. J Bronchology Interv Pulmonol. 2023 Jan 1;30(1):37-46. doi: 10.1097/LBR.0000000000000842.

Week 1 (02.01.-08.01.)

Thoracic surgery in the non-intubated spontaneously breathing patient. Grott M, Eichhorn M, Eichhorn F, Schmidt W, Kreuter M, Winter H. Respir Res. 2022 Dec 27;23(1):379. doi: 10.1186/s12931-022-02250-z. PMID: 36575519. Review.

Home monitoring in interstitial lung diseases. Wijsenbeek MS, Moor CC, Johannson KA, Jackson PD, Khor YH, Kondoh Y, Rajan SK, Tabaj GC, Varela BE, van der Wal P, van Zyl-Smit RN, Kreuter M, Maher TM. Lancet Respir Med. 2023 Jan;11(1):97-110. doi: 10.1016/S2213-2600(22)00228-4. Epub 2022 Oct 4. PMID: 36206780 Review.

Anti-SARS-CoV-2 antibody-containing plasma improves outcome in patients with hematologic or solid cancer and severe COVID-19: a randomized clinical trial. Denkinger CM, Janssen M, Schäkel U, Gall J, Leo A, Stelmach P, Weber SF, Krisam J, Baumann L, Stermann J, Merle U, Weigand MA, Nusshag C, Bullinger L, Schrezenmeier JF, Bornhäuser M, Alakel N, Witzke O, Wolf T, Vehreschild MJGT, Schmiedel S, Addo MM, Herth F, Kreuter M, Tepasse PR, Hertenstein B, Hänel M, Morgner A, Kiehl M, Hopfer O, Wattad MA, Schimanski CC, Celik C, Pohle T, Ruhe M, Kern WV, Schmitt A, Lorenz HM, Souto-Carneiro M, Gaeddert M, Halama N, Meuer S, Kräusslich HG, Müller B, Schnitzler P, Parthé S, Bartenschlager R, Gronkowski M, Klemmer J, Schmitt M, Dreger P, Kriegsmann K, Schlenk RF, Müller-Tidow C. Nat Cancer. 2022 Dec 29. doi: 10.1038/s43018-022-00503-w. Online ahead of print. PMID: 36581734

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