Frederik Trinkmann is working as a consultant at Thoraxklinik Heidelberg at Heidelberg University Hospital and is responsible for the asthma section. Additionally, he is a scientist at the Department of Biomedical Informatics of the Heinrich-Lanz-Center for Digital Health as part of the medical informatics initiative MIRACUM. After graduating from medical school in Heidelberg/Mannheim he was working as a Clinician Scientist at University Medical Center Mannheim, recently being the head of pulmonary research. He is a specialist for internal medicine, pneumology and intensive care medicine. Since 2020 he serves as principal investigator for disease areas Asthma&Allergy and COPD as part of DZL.
- Phenotyping, early detection and differential therapy of obstructive lung disease
- Cardiorespiratory interaction
- Secondary use of clinical routine data
- Asthma & Allergy
- Chronic Obstructive Pulmonary Disease
- Trinkmann F, Maros M, Roth K, Hermanns A, Schäfer J, Gawlitza J, Saur J, Akin I, Borggrefe M, Herth FJF, Ganslandt T. Multiple breath washout (MBW) testing using sulfur hexafluoride: reference values and influence of anthropometric parameters. Thorax 2021 Feb 16:thoraxjnl-2020-214717. doi: 10.1136/thoraxjnl-2020-214717. Online ahead of print. PMID: 33593931
- Trinkmann F, Müller M, Reif A, Kahn N, Kreuter M, Trudzinski F, Eichinger M, Heussel CP, Herth FJF; Lung Network Rhine-Neckar-Region (2021). Residual symptoms and lower lung function in patients recovering from SARS-CoV-2 infection. Eur Respir J. 2021 Jan 21:2003002. doi: 10.1183/13993003.03002-2020
- Trinkmann F, Lenz SA, Schäfer J, Gawlitza J, Schroeter M, Gradinger T, Akin I, Borggrefe M, Ganslandt T, Saur J (2020). Feasibility and clinical applications of multiple breath wash-out (MBW) testing using sulphur hexafluoride in adults with bronchial asthma. Sci Rep 30;10(1):1527.
- Gawlitza J, Haubenreisser H, Henzler T, Akin I, Schönberg S, Borggrefe M, Trinkmann F (2018). Finding the right spot: Where to measure airway parameters in patients with COPD. Eur J Radiol: 104:87-93.
- TrinkmannF, Watz H, Herth FJ (2020). Why do we still cling to spirometry for assessing small airway function? (Eur Resp J, in press)
- Schumacher G, Kaden JJ, Trinkmann F (2018). Multiple coupled resonances in the human vascular tree: refining the Westerhof model of the arterial system. J Appl Physiol 1;124(1):131-139.
- Saur J, Fluechter S, Trinkmann F, Papavassiliu T, Schoenberg S, Weissmann J, Haghi D, Borggrefe M, Kaden JJ (2009). Noninvasive determination of cardiac output by the inert-gas-rebreathing method--comparison with cardiovascular magnetic resonance imaging. Cardiology 114(4):247-54.
Lung Research - Projects
- Phenotyping, early diagnosis and differential therapy of obstructive lung disease
Bronchial asthma and chronic obstructive pulmonary disease (COPD) are amongst the most frequent lung diseases and associated with considerable morbidity and mortality. Diagnostic work-up and early detection therefore is of utmost importance and bears the potential to improve personalized treatment options. - Cardiorespiratory interaction
Cardiac comorbidities are common in patients with lung disease. Their coincidence cannot be attributed to shared risk factors such as cigarette smoking alone. Moreover, complex pathophysiological interactions exist which may serve as a therapeutic or preventive target. - Secondary use of clinical routine data
Huge quantities of data are produced during routine clinical care. However, they still cannot be adequately used for neither patient treatment nor scientific use due to technological restraints. Digitalization and ongoing structural improvements will offer opportunities to increase the clinical and scientifical value of existing data.
