Publikationen

Diese Woche neu in PubMed TLRC Faculty - 2017

Woche 52

Resolving the Combinatorial Complexity of Smad Protein Complex Formation and Its Link to Gene Expression.
Lucarelli P, Schilling M, Kreutz C, Vlasov A, Boehm ME, Iwamoto N, Steiert B, Lattermann S, Wäsch M, Stepath M, Matter MS, Heikenwälder M, Hoffmann K, Deharde D, Damm G, Seehofer D, Muciek M, Gretz N, Lehmann WD, Timmer J, Klingmüller U.
Cell Syst. 2017 Dec 12. pii: S2405-4712(17)30538-0. doi: 10.1016/j.cels.2017.11.010. [Epub ahead of print] PMID: 29248373 [PubMed - as supplied by publisher] Free Article

FOXM1 activates AGR2 and causes progression of lung adenomas into invasive mucinous adenocarcinomas.
Milewski D, Balli D, Ustiyan V, Le T, Dienemann H, Warth A, Breuhahn K, Whitsett JA, Kalinichenko VV, Kalin TV.
PLoS Genet. 2017 Dec 21;13(12):e1007097. doi: 10.1371/journal.pgen.1007097. [Epub ahead of print] PMID: 29267283 [PubMed - as supplied by publisher]

A Multicenter Randomized Controlled Trial of Zephyr Endobronchial Valve Treatment in Heterogeneous Emphysema (TRANSFORM).
Kemp SV, Slebos DJ, Kirk A, Kornaszewska M, Carron K, Ek L, Broman G, Hillerdal G, Mal H, Pison C, Briault A, Downer N, Darwiche K, Rao J, Hübner RH, Ruwwe-Glosenkamp C, Trosini-Desert V, Eberhardt R, Herth FJ, Derom E, Malfait T, Shah PL, Garner JL, Ten Hacken NH, Fallouh H, Leroy S, Marquette CH; TRANSFORM Study Team * .
Am J Respir Crit Care Med. 2017 Dec 15;196(12):1535-1543. doi: 10.1164/rccm.201707-1327OC. PMID: 28885054 [PubMed - indexed for MEDLINE]

Riociguat in patients with chronic thromboembolic pulmonary hypertension: results from an early access study.
McLaughlin VV, Jansa P, Nielsen-Kudsk JE, Halank M, Simonneau G, Grünig E, Ulrich S, Rosenkranz S, Gómez Sánchez MA, Pulido T, Pepke-Zaba J, Barberá JA, Hoeper MM, Vachiéry JL, Lang I, Carvalho F, Meier C, Mueller K, Nikkho S, D'Armini AM.
BMC Pulm Med. 2017 Dec 28;17(1):216. doi: 10.1186/s12890-017-0563-7. PMID: 29282032 [PubMed - in process]

ERS International Congress 2017: a peek of outstanding abstracts from the clinical assembly.
Kahn N, Andrianopoulos V, Mekov E, Herth FJF.
J Thorac Dis. 2017 Nov;9(Suppl 16):S1526-S1531. doi: 10.21037/jtd.2017.11.43. Review. PMID: 29255633 [PubMed] Free PMC Article

Assessment of pulmonary vascular response to exercise with Doppler-echocardiography: state of the art?
Marra AM, Grünig E.
J Thorac Dis. 2017 Oct;9(10):3607-3608. doi: 10.21037/jtd.2017.09.45. No abstract available. PMID: 29268353 [PubMed]

An informative intragenic microsatellite marker suggests the IL-1 receptor as a genetic modifier in cystic fibrosis.
Stanke F, Hector A, Hedtfeld S, Hartl D, Griese M, Tümmler B, Mall MA.
Eur Respir J. 2017 Dec 28;50(6). pii: 1700426. doi: 10.1183/13993003.00426-2017. Print 2017 Dec. No abstract available.  PMID: 29284683 [PubMed - in process
 

Woche 51

Role of Conventional Immunomarkers, HNF4-a, and SATB2 in the Differential Diagnosis of Pulmonary and Colorectal Adenocarcinomas.
Kriegsmann M, Harms A, Longuespée R, Muley T, Winter H, Kriegsmann K, Kazdal D, Goeppert B, Pathil A, Warth A.
Histopathology. 2017 Dec 15. doi: 10.1111/his.13455. [Epub ahead of print] PMID: 29243296 [PubMed - as supplied by publisher]

Patients with IPF and lung cancer: diagnosis and management.
Tzouvelekis A, Spagnolo P, Bonella F, Vancheri C, Tzilas V, Crestani B, Kreuter M, Bouros D.
Lancet Respir Med. 2017 Dec 11. pii: S2213-2600(17)30478-2. doi: 10.1016/S2213-2600(17)30478-2. [Epub ahead of print] No abstract available.  PMID: 29241977 [PubMed - as supplied by publisher]

Cystic fibrosis research topics featured at the 14th ECFS Basic Science Conference: Chairman's summary.
Mall MA, Hwang TC, Brakman I.
J Cyst Fibros. 2017 Dec 8. pii: S1569-1993(17)30965-7. doi: 10.1016/j.jcf.2017.11.008. [Epub ahead of print] PMID: 29229473 [PubMed - as supplied by publisher]

Trans-esophageal endobronchial ultrasound-guided needle aspiration (EUS-B-NA): A road map for the chest physician.
Bugalho A, de Santis M, Slubowski A, Rozman A, Eberhardt R.
Rev Port Pneumol (2006). 2017 Dec 11. pii: S2173-5115(17)30162-8. doi: 10.1016/j.rppnen.2017.10.004. [Epub ahead of print] PMID: 29242047 [PubMed - as supplied by publisher]
 

Woche 50

Lung volume reduction for emphysema.
Shah PL, Herth FJ, van Geffen WH, Deslee G, Slebos DJ.
Lancet Respir Med. 2017 Feb;5(2):147-156. doi: 10.1016/S2213-2600(16)30221-1. Epub 2016 Sep 29. Review. PMID: 27693408 [PubMed - indexed for MEDLINE]

European position statement on lung cancer screening.
Oudkerk M, Devaraj A, Vliegenthart R, Henzler T, Prosch H, Heussel CP, Bastarrika G, Sverzellati N, Mascalchi M, Delorme S, Baldwin DR, Callister ME, Becker N, Heuvelmans MA, Rzyman W, Infante MV, Pastorino U, Pedersen JH, Paci E, Duffy SW, de Koning H, Field JK.
Lancet Oncol. 2017 Dec;18(12):e754-e766. doi: 10.1016/S1470-2045(17)30861-6. Review. PMID: 29208441 [PubMed - in process]

Repaglinide versus insulin for newly diagnosed diabetes in patients with cystic fibrosis: a multicentre, open-label, randomised trial.
Ballmann M, Hubert D, Assael BM, Staab D, Hebestreit A, Naehrlich L, Nickolay T, Prinz N, Holl RW; CFRD Study Group.
Lancet Diabetes Endocrinol. 2017 Nov 30. pii: S2213-8587(17)30400-X. doi: 10.1016/S2213-8587(17)30400-X. [Epub ahead of print] PMID: 29199116 [PubMed - as supplied by publisher]

A Field Guide for Cancer Diagnostics using cell-free DNA: From Principles to Practice and Clinical Applications.
Volckmar AL, Sültmann H, Riediger A, Fioretos T, Schirmacher P, Endris V, Stenzinger A, Dietz S.
Genes Chromosomes Cancer. 2017 Dec 5. doi: 10.1002/gcc.22517. [Epub ahead of print] Review. PMID: 29205637 [PubMed - as supplied by publisher]
 

Woche 49

Evaluation of NGS and RT-PCR methods for ALK rearrangement in European NSCLC patients: Results from the ETOP Lungscape Project.
Letovanec I, Finn S, Zygoura P, Smyth P, Soltermann A, Bubendorf L, Speel EJ, Marchetti A, Nonaka D, Monkhorst K, Hager H, Martorell M, Sejda A, Cheney R, Hernandez-Losa J, Verbeken E, Weder W, Savic S, Di Lorito A, Navarro A, Felip E, Warth A, Baas P, Meldgaard P, Blackhall F, Dingemans AM, Dienemann H, Dziadziuszko R, Vansteenkiste J, O'Brien C, Geiger T, Sherlock J, Schageman J, Dafni U, Kammler R, Kerr K, Thunnissen E, Stahel R, Peters S; ETOP Lungscape Consortium.
J Thorac Oncol. 2017 Nov 27. pii: S1556-0864(17)33063-0. doi: 10.1016/j.jtho.2017.11.117. [Epub ahead of print]

Prevalence and clinical association of gene mutations through Multiplex Mutation Testing in patients with NSCLC: Results from the ETOP Lungscape Project.
Kerr KM, Dafni U, Schulze K, Thunnissen E, Bubendorf L, Hager H, Finn S, Biernat W, Vliegen L, Losa JH, Marchetti A, Cheney R, Warth A, Speel EJ, Blackhall F, Monkhorst K, Jantus Lewintre E, Tischler V, Clark C, Bertran-Alamillo J, Meldgaard P, Gately K, Wrona A, Vandenberghe P, Felip E, De Luca G, Savic S, Muley T, Smit EF, Dingemans AC, Priest L, Baas P, Camps C, Weder W, Polydoropoulou V, Geiger TR, Kammler R, Sumiyoshi T, Molina MA, Shames DS, Stahel RA, Peters S; ETOP Lungscape Consortium.
Ann Oncol. 2017 Nov 23. doi: 10.1093/annonc/mdx629. [Epub ahead of print] PMID: 29186353 [PubMed - as supplied by publisher]

C-reactive protein-albumin ratio is an independent prognostic predictor of tumor recurrence in stage IIIA-N2 lung adenocarcinoma patients.
Yamauchi Y, Safi S, Muley T, Warth A, Herth FJF, Dienemann H, Hoffmann H, Eichhorn ME.
Lung Cancer. 2017 Dec;114:62-67. doi: 10.1016/j.lungcan.2017.11.002. Epub 2017 Nov 3. PMID: 29173768 [PubMed - in process]

Outcomes in patients with aggressive or refractory disease from REVEL: A randomized phase III study of docetaxel with ramucirumab or placebo for second-line treatment of stage IV non-small-cell lung cancer.
Reck M, Paz-Ares L, Bidoli P, Cappuzzo F, Dakhil S, Moro-Sibilot D, Borghaei H, Johnson M, Jotte R, Pennell NA, Shepherd FA, Tsao A, Thomas M, Carter GC, Chan-Diehl F, Alexandris E, Lee P, Zimmermann A, Sashegyi A, Pérol M.
Lung Cancer. 2017 Oct;112:181-187. doi: 10.1016/j.lungcan.2017.07.038. Epub 2017 Aug 5. PMID: 29191593 [PubMed - in process]

Screening drug effects in patient-derived cancer cells links organoid responses to genome alterations.
Jabs J, Zickgraf FM, Park J, Wagner S, Jiang X, Jechow K, Kleinheinz K, Toprak UH, Schneider MA, Meister M, Spaich S, Sütterlin M, Schlesner M, Trumpp A, Sprick M, Eils R, Conrad C.
Mol Syst Biol. 2017 Nov 27;13(11):955. doi: 10.15252/msb.20177697. PMID: 29180611 [PubMed - in process] Free Article

Predictors of clinical outcome in emphysema patients with atelectasis following endoscopic valve therapy: A retrospective study.
Gompelmann D, Hofbauer T, Gerovasili V, Eberhardt R, Lim HJ, Herth F, Heussel CP.
Respirology. 2016 Oct;21(7):1255-61. doi: 10.1111/resp.12819. Epub 2016 Jun 1. PMID: 27250924 [PubMed - indexed for MEDLINE]

Motion monitoring during a course of lung radiotherapy with anchored electromagnetic transponders : Quantification of inter- and intrafraction motion and variability of relative transponder positions.
Schmitt D, Nill S, Roeder F, Gompelmann D, Herth F, Oelfke U.
Strahlenther Onkol. 2017 Oct;193(10):840-847. doi: 10.1007/s00066-017-1183-0. Epub 2017 Jul 21. PMID: 28733724 [PubMed - indexed for MEDLINE] Free PMC Article

Computed Tomography: The Better Pulmonologist?
Herth FJF, Schuhmann M.
Respiration. 2017;94(4):331-333. doi: 10.1159/000479332. Epub 2017 Aug 18. No abstract available.  PMID: 28817818 [PubMed - indexed for MEDLINE]
 

Woche 48

Iron Induces Anti-tumor Activity in Tumor-Associated Macrophages.
Costa da Silva M, Breckwoldt MO, Vinchi F, Correia MP, Stojanovic A, Thielmann CM, Meister M, Muley T, Warth A, Platten M, Hentze MW, Cerwenka A, Muckenthaler MU.
Front Immunol. 2017 Nov 8;8:1479. doi: 10.3389/fimmu.2017.01479. eCollection 2017. PMID: 29167669 [PubMed] Free Article

Selecting high-risk individuals for lung cancer screening; the use of risk prediction models vs. simplified eligibility criteria.
Kaaks R, Hüsing A, Fortner RT.
Ann Transl Med. 2017 Oct;5(20):406. doi: 10.21037/atm.2017.07.14. No abstract available.  PMID: 29152506 [PubMed] Free PMC Article

An official European Respiratory Society statement: pulmonary haemodynamics during exercise.
Kovacs G, Herve P, Barbera JA, Chaouat A, Chemla D, Condliffe R, Garcia G, Grünig E, Howard L, Humbert M, Lau E, Laveneziana P, Lewis GD, Naeije R, Peacock A, Rosenkranz S, Saggar R, Ulrich S, Vizza D, Vonk Noordegraaf A, Olschewski H.
Eur Respir J. 2017 Nov 22;50(5). pii: 1700578. doi: 10.1183/13993003.00578-2017. Print 2017 Nov. PMID: 29167297 [PubMed - in process]

A longitudinal communication approach in advanced lung cancer: A qualitative study of patients', relatives' and staff's perspectives.
Villalobos M, Coulibaly K, Krug K, Kamradt M, Wensing M, Siegle A, Kuon J, Eschbach C, Tessmer G, Winkler E, Szecsenyi J, Ose D, Thomas M.
Eur J Cancer Care (Engl). 2017 Nov 23. doi: 10.1111/ecc.12794. [Epub ahead of print] PMID: 29168594 [PubMed - as supplied by publisher]
 

Woche 47

Functional T cells targeting tumor-associated antigens are predictive for recurrence-free survival of patients with radically operated non-small cell lung cancer.
Safi S, Yamauchi Y, Rathinasamy A, Stamova S, Eichhorn M, Warth A, Rauch G, Dienemann H, Hoffmann H, Beckhove P.
Oncoimmunology. 2017 Sep 8;6(11):e1360458. doi: 10.1080/2162402X.2017.1360458. eCollection 2017. PMID: 29147626 [PubMed]

nab-paclitaxel/carboplatin induction in squamous NSCLC: longitudinal quality of life while on chemotherapy.
Thomas M, Spigel DR, Jotte RM, McCleod M, Socinski MA, Page RD, Gressot L, Knoble J, Juan O, Morgensztern D, Isla D, Kim ES, West H, Ko A, Ong TJ, Trunova N, Gridelli C.
Lung Cancer (Auckl). 2017 Oct 30;8:207-216. doi: 10.2147/LCTT.S138570. eCollection 2017. PMID: 29138610 [PubMed] Free PMC Article
 

Woche 46

CD13 as target for tissue factor induced tumor vascular infarction in small cell lung cancer.
Schmidt LH, Stucke-Ring J, Brand C, Schliemann C, Harrach S, Muley T, Herpel E, Kessler T, Mohr M, Görlich D, Kreuter M, Lenz G, Wardelmann E, Thomas M, Berdel WE, Schwöppe C, Hartmann W.
Lung Cancer. 2017 Nov;113:121-127. doi: 10.1016/j.lungcan.2017.09.013. Epub 2017 Sep 22.PMID: 29110838 [PubMed - in process]

Interobserver Variation Among Pathologists And Refinement Of Criteria In Distinguishing Separate Primary Tumours From Intrapulmonary Metastases In Lung.
Nicholson AG, Torkko K, Viola P, Duhig E, Geisinger K, Borczuk AC, Hiroshima K, Tsao MS, Warth A, Lantuejoul S, Russell PA, Thunnissen E, Marchevsky A, Mino-Kenudson M, Beasley MB, Botling J, Dacic S, Yatabe Y, Noguchi M, Travis WD, Kerr K, Hirsch FR, Chirieac LR, Wistuba II, Moreira A, Chung JH, Chou TY, Bubendorf L, Chen G, Pelosi G, Poleri C, Detterbeck FC, Franklin WA.
J Thorac Oncol. 2017 Nov 7. pii: S1556-0864(17)32863-0. doi: 10.1016/j.jtho.2017.10.019. [Epub ahead of print]

EGFR immunohistochemistry as biomarker for antibody-based therapy of squamous NSCLC - Experience from the first ring trial of the German Quality Assurance Initiative for Pathology (QuIP^®).
Petersen I, Dietel M, Geilenkeuser WJ, Mireskandari M, Weichert W, Steiger K, Scheel AH, Büttner R, Schirmacher P, Warth A, Lasitschka F, Schildhaus HU, Kirchner T, Reu S, Kreipe H, Länger F, Tiemann M, Schulte C, Jöhrens K.
Pathol Res Pract. 2017 Sep 28. pii: S0344-0338(17)30810-5. doi: 10.1016/j.prp.2017.09.021. [Epub ahead of print] PMID: 29108919 [PubMed - as supplied by publisher]

Spread through air spaces (STAS): a comprehensive update.
Warth A.
Transl Lung Cancer Res. 2017 Oct;6(5):501-507. doi: 10.21037/tlcr.2017.06.08. Review. PMID: 29114466 [PubMed] Free PMC Article

Endobronchial valve placement in emphysema: When is it lung volume reduction?
Eberhardt R.
Respirology. 2017 Nov 5. doi: 10.1111/resp.13217. [Epub ahead of print] No abstract available. PMID: 29105909 [PubMed - as supplied by publisher] Free Article

Homeostatic nuclear RAGE-ATM interaction is essential for efficient DNA repair.
Kumar V, Fleming T, Terjung S, Gorzelanny C, Gebhardt C, Agrawal R, Mall MA, Ranzinger J, Zeier M, Madhusudhan T, Ranjan S, Isermann B, Liesz A, Deshpande D, Häring HU, Biswas SK, Reynolds PR, Hammes HP, Peperkok R, Angel P, Herzig S, Nawroth PP.
Nucleic Acids Res. 2017 Oct 13;45(18):10595-10613. doi: 10.1093/nar/gkx705. PMID: 28977635 [PubMed - indexed for MEDLINE]
 

Woche 45

Outcome and prognostic factors in single brain metastases from small-cell lung cancer.
Bernhardt D, Adeberg S, Bozorgmehr F, Opfermann N, Hörner-Rieber J, König L, Kappes J, Thomas M, Unterberg A, Herth F, Heußel CP, Warth A, Debus J, Steins M, Rieken S.
Strahlenther Onkol. 2017 Oct 30. doi: 10.1007/s00066-017-1228-4. [Epub ahead of print] PMID: 29085978 [PubMed - as supplied by publisher]

CT characteristics in pulmonary adenocarcinoma with epidermal growth factor receptor mutation.
Zhao J, Dinkel J, Warth A, Penzel R, Reinmuth N, Schnabel P, Muley T, Meister M, Zabeck H, Steins M, Yang JY, Zhou Q, Schlemmer HP, Herth FJF, Kauczor HU, Heussel CP.
PLoS One. 2017 Sep 26;12(9):e0182741. doi: 10.1371/journal.pone.0182741. eCollection 2017. PMID: 28949965 [PubMed - indexed for MEDLINE] Free PMC Article
 

Woche 44

Lung disease phenotypes caused by over-expression of combinations of alpha, beta, and gamma subunits of the epithelial sodium channel in mouse airways.
Livraghi-Butrico A, Wilkinson KJ, Volmer AS, Gilmore RC, Rogers TD, Caldwell RA, Burns KA, Esther CR Jr, Mall MA, Boucher RC, O'Neal WK, Grubb BR.Am J Physiol Lung Cell Mol Physiol. 2017 Oct 26:ajplung.00382.2017. doi: 10.1152/ajplung.00382.2017. [Epub ahead of print] PMID: 29074490 [PubMed - as supplied by publisher]

Bypassing CFTR dysfunction in cystic fibrosis with alternative pathways for anion transport.
Li H, Salomon JJ, Sheppard DN, Mall MA, Galietta LJ.
Curr Opin Pharmacol. 2017 Oct 21;34:91-97. doi: 10.1016/j.coph.2017.10.002. [Epub ahead of print] Review. PMID: 29065356 [PubMed - as supplied by publisher]

Acute effects of exercise on the inflammatory state in patients with idiopathic pulmonary arterial hypertension.
Harbaum L, Renk E, Yousef S, Glatzel A, Lüneburg N, Hennigs JK, Oqueka T, Baumann HJ, Atanackovic D, Grünig E, Böger RH, Bokemeyer C, Klose H.
BMC Pulm Med. 2016 Nov 11;16(1):145. PMID: 27835955 [PubMed - indexed for MEDLINE] Free PMC Article

Factors associated with disease progression in early-diagnosed pulmonary arterial hypertension associated with systemic sclerosis: longitudinal data from the DETECT cohort.
Mihai C, Antic M, Dobrota R, Bonderman D, Chadha-Boreham H, Coghlan JG, Denton CP, Doelberg M, Grünig E, Khanna D, McLaughlin VV, Müller-Ladner U, Pope JE, Rosenberg DM, Seibold JR, Vonk MC, Distler O.
Ann Rheum Dis. 2017 Oct 23. pii: annrheumdis-2017-211480. doi: 10.1136/annrheumdis-2017-211480. [Epub ahead of print] PMID: 29061853 [PubMed - as supplied by publisher]

3D dosimetric validation of motion compensation concepts in radiotherapy using an anthropomorphic dynamic lung phantom.
Mann P, Witte M, Moser T, Lang C, Runz A, Johnen W, Berger M, Biederer J, Karger CP.
Phys Med Biol. 2017 Jan 21;62(2):573-595. doi: 10.1088/1361-6560/aa51b1. Epub 2016 Dec 29. PMID: 28033114 [PubMed - indexed for MEDLINE]

Endobronchial Ultrasound Elastography for Evaluation of Intrathoracic Lymph Nodes: A Pilot Study.
Sun J, Zheng X, Mao X, Wang L, Xiong H, Herth FJF, Han B.
Respiration. 2017;93(5):327-338. doi: 10.1159/000464253. Epub 2017 Mar 22. PMID: 28324873 [PubMed - indexed for MEDLINE]

Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population.
Li Y, Xiao X, Han Y, Gorlova O, Qian D, Leighl N, Johansen JS, Barnett M, Chen C, Goodman G, Cox A, Taylor F, Woll P, Wichmann HE, Manz J, Muley T, Risch A, Rosenberger A, Arnold SM, Haura EB, Bolca C, Holcatova I, Janout V, Kontic M, Lissowska J, Mukeria A, Ognjanovic S, Orlowski TM, Scelo G, Swiatkowska B, Zaridze D, Bakke P, Skaug V, Zienolddiny S, Duell EJ, Butler LM, Houlston R, Artigas MS, Grankvist K, Johansson M, Shepherd FA, Marcus MW, Brunnström H, Manjer J, Melander O, Muller DC, Overvad K, Trichopoulou A, Tumino R, Liu G, Bojesen SE, Wu X, Le Marchand L, Albanes D, Bickeböller H, Aldrich MC, Bush WS, Tardon A, Rennert G, Teare MD, Field JK, Kiemeney LA, Lazarus P, Haugen A, Lam S, Schabath MB, Andrew AS, Bertazzi PA, Pesatori AC, Christiani DC, Caporaso N, Johansson M, McKay JD, Brennan P, Hung RJ, Amos CI.
Carcinogenesis. 2017 Oct 20. doi: 10.1093/carcin/bgx113. [Epub ahead of print] PMID: 29059373 [PubMed - as supplied by publisher]

Results from the European Prospective Investigation into Cancer and Nutrition (EPIC) link vitamin B6 catabolism and lung cancer risk.
Zuo H, Ueland PM, Midttun Ø, Vollset SE, Tell GS, Theofylaktopoulou D, Travis RC, Boutron-Ruault MC, Fournier A, Severi G, Kvaskoff M, Boeing H, Bergmann M, Fortner RT, Kaaks R, Trichopoulou A, Kotanidou A, Lagiou P, Palli D, Sieri S, Panico S, Bueno-de-Mesquita HBA, Peeters PH, Grankvist K, Johansson M, Agudo A, Quirós Garcia JR, Larrañaga N, Sanchez MJ, Chirlaque MD, Ardanaz E, Chuang SC, Gallo V, Brennan P, Johansson M, Ulvik A.
Cancer Res. 2017 Oct 25. pii: canres.1923.2017. doi: 10.1158/0008-5472.CAN-17-1923. [Epub ahead of print] PMID: 29070616 [PubMed - as supplied by publisher]
 

Woche 43

Targeted Deep Sequencing of Effusion Cytology Samples is Feasible, informs Spatiotemporal Tumor Evolution, and has Clinical and Diagnostic Utility.
Leichsenring J, Volckmar AL, Kirchner M, Kazdal D, Kriegsmann M, Stögbauer F, Bockmayr T, Klauschen F, Herth FJF, Penzel R, Warth A, Schirmacher P, Endris V, Stenzinger A.
Genes Chromosomes Cancer. 2017 Oct 16. doi: 10.1002/gcc.22509. [Epub ahead of print] PMID: 29044880 [PubMed - as supplied by publisher]

POSITIVE study: physical exercise program in non-operable lung cancer patients undergoing palliative treatment.
Wiskemann J, Hummler S, Diepold C, Keil M, Abel U, Steindorf K, Beckhove P, Ulrich CM, Steins M, Thomas M.
BMC Cancer. 2016 Jul 19;16:499. doi: 10.1186/s12885-016-2561-1. PMID: 27430336 [PubMed - indexed for MEDLINE] Free PMC Article

Palliative care in interstitial lung disease: living well.
Kreuter M, Bendstrup E, Russell AM, Bajwah S, Lindell K, Adir Y, Brown CE, Calligaro G, Cassidy N, Corte TJ, Geissler K, Hassan AA, Johannson KA, Kairalla R, Kolb M, Kondoh Y, Quadrelli S, Swigris J, Udwadia Z, Wells A, Wijsenbeek M.
Lancet Respir Med. 2017 Oct 12. pii: S2213-2600(17)30383-1. doi: 10.1016/S2213-2600(17)30383-1. [Epub ahead of print] Review. PMID: 29033267 [PubMed - as supplied by publisher]
 

Woche 42

Long-term treatment of patients with idiopathic pulmonary fibrosis with nintedanib: results from the TOMORROW trial and its open-label extension.
Richeldi L, Kreuter M, Selman M, Crestani B, Kirsten AM, Wuyts WA, Xu Z, Bernois K, Stowasser S, Quaresma M, Costabel U.
Thorax. 2017 Oct 9. pii: thoraxjnl-2016-209701. doi: 10.1136/thoraxjnl-2016-209701. [Epub ahead of print] PMID: 28993537 [PubMed - as supplied by publisher] Free Article

Influence of fissure integrity on quantitative CT and emphysema distribution in emphysema-type COPD using a dedicated COPD software.
Müller J, Lim HJ, Eichinger M, Jobst BJ, Eberhardt R, Gompelmann D, Koenigkam-Santos M, Puderbach M, Kauczor HU, Heussel CP, Wielpütz MO.
Eur J Radiol. 2017 Oct;95:293-299. doi: 10.1016/j.ejrad.2017.08.015. Epub 2017 Aug 19. PMID: 28987683 [PubMed - in process]
 

Woche 41

Chronic but not intermittent infection with <i>Pseudomonas aeruginosa</i> is associated with global changes of the lung microbiome in cystic fibrosis.
Boutin S, Graeber SY, Stahl M, Dittrich AS, Mall MA, Dalpke AH.
Eur Respir J. 2017 Oct 5;50(4). pii: 1701086. doi: 10.1183/13993003.01086-2017. Print 2017 Oct. No abstract available.  PMID: 28982777 [PubMed - in process]

Homeostatic nuclear RAGE-ATM interaction is essential for efficient DNA repair.
Kumar V, Fleming T, Terjung S, Gorzelanny C, Gebhardt C, Agrawal R, Mall MA, Ranzinger J, Zeier M, Madhusudhan T, Ranjan S, Isermann B, Liesz A, Deshpande D, Häring HU, Biswas SK, Reynolds PR, Hammes HP, Peperkok R, Angel P, Herzig S, Nawroth PP.
Nucleic Acids Res. 2017 Aug 9. doi: 10.1093/nar/gkx705. [Epub ahead of print] PMID: 28977635 [PubMed - as supplied by publisher]

Parenchymal and Functional Lung Changes after Stereotactic Body Radiotherapy for Early-Stage Non-Small Cell Lung Cancer-Experiences from a Single Institution.
Hörner-Rieber J, Dern J, Bernhardt D, König L, Adeberg S, Verma V, Paul A, Kappes J, Hoffmann H, Debus J, Heussel CP, Rieken S.
Front Oncol. 2017 Sep 19;7:215. doi: 10.3389/fonc.2017.00215. eCollection 2017. PMID: 28975083 [PubMed] Free PMC Article

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
McKay JD, Hung RJ, Han Y, Zong X, Carreras-Torres R, Christiani DC, Caporaso NE, Johansson M, Xiao X, Li Y, Byun J, Dunning A, Pooley KA, Qian DC, Ji X, Liu G, Timofeeva MN, Bojesen SE, Wu X, Le Marchand L, Albanes D, Bickeböller H, Aldrich MC, Bush WS, Tardon A, Rennert G, Teare MD, Field JK, Kiemeney LA, Lazarus P, Haugen A, Lam S, Schabath MB, Andrew AS, Shen H, Hong YC, Yuan JM, Bertazzi PA, Pesatori AC, Ye Y, Diao N, Su L, Zhang R, Brhane Y, Leighl N, Johansen JS, Mellemgaard A, Saliba W, Haiman CA, Wilkens LR, Fernandez-Somoano A, Fernandez-Tardon G, van der Heijden HFM, Kim JH, Dai J, Hu Z, Davies MPA, Marcus MW, Brunnström H, Manjer J, Melander O, Muller DC, Overvad K, Trichopoulou A, Tumino R, Doherty JA, Barnett MP, Chen C, Goodman GE, Cox A, Taylor F, Woll P, Brüske I, Wichmann HE, Manz J, Muley TR, Risch A, Rosenberger A, Grankvist K, Johansson M, Shepherd FA, Tsao MS, Arnold SM, Haura EB, Bolca C, Holcatova I, Janout V, Kontic M, Lissowska J, Mukeria A, Ognjanovic S, Orlowski TM, Scelo G, Swiatkowska B, Zaridze D, Bakke P, Skaug V, Zienolddiny S, Duell EJ, Butler LM, Koh WP, Gao YT, Houlston RS, McLaughlin J, Stevens VL, Joubert P, Lamontagne M, Nickle DC, Obeidat M, Timens W, Zhu B, Song L, Kachuri L, Artigas MS, Tobin MD, Wain LV; SpiroMeta Consortium, Rafnar T, Thorgeirsson TE, Reginsson GW, Stefansson K, Hancock DB, Bierut LJ, Spitz MR, Gaddis NC, Lutz SM, Gu F, Johnson EO, Kamal A, Pikielny C, Zhu D, Lindströem S, Jiang X, Tyndale RF, Chenevix-Trench G, Beesley J, Bossé Y, Chanock S, Brennan P, Landi MT, Amos CI.
Nat Genet. 2017 Jul;49(7):1126-1132. doi: 10.1038/ng.3892. Epub 2017 Jun 12. PMID: 28604730 [PubMed - indexed for MEDLINE]
 

Woche 40

CT characteristics in pulmonary adenocarcinoma with epidermal growth factor receptor mutation.
Zhao J, Dinkel J, Warth A, Penzel R, Reinmuth N, Schnabel P, Muley T, Meister M, Zabeck H, Steins M, Yang JY, Zhou Q, Schlemmer HP, Herth FJF, Kauczor HU, Heussel CP.
PLoS One. 2017 Sep 26;12(9):e0182741. doi: 10.1371/journal.pone.0182741. eCollection 2017. PMID: 28949965 [PubMed - in process] Free Article

Gene signature driving invasive mucinous adenocarcinoma of the lung.
Guo M, Tomoshige K, Meister M, Muley T, Fukazawa T, Tsuchiya T, Karns R, Warth A, Fink-Baldauf IM, Nagayasu T, Naomoto Y, Xu Y, Mall MA, Maeda Y.
EMBO Mol Med. 2017 Apr;9(4):462-481. doi: 10.15252/emmm.201606711. PMID: 28255028 [PubMed - indexed for MEDLINE] Free PMC Article

Correlated receptor transport processes buffer single-cell heterogeneity.
Kallenberger SM, Unger AL, Legewie S, Lymperopoulos K, Klingmüller U, Eils R, Herten DP.
PLoS Comput Biol. 2017 Sep 25;13(9):e1005779. doi: 10.1371/journal.pcbi.1005779. [Epub ahead of print] PMID: 28945754 [PubMed - as supplied by publisher] Free Article

Influence of exposure parameters and iterative reconstruction on automatic airway segmentation and analysis on MDCT-An ex vivo phantom study.
Leutz-Schmidt P, Weinheimer O, Jobst BJ, Dinkel J, Biederer J, Kauczor HU, Puderbach MU, Wielpütz MO.
PLoS One. 2017 Aug 2;12(8):e0182268. doi: 10.1371/journal.pone.0182268. eCollection 2017. PMID: 28767732 [PubMed - indexed for MEDLINE] Free PMC Article

[Screening for Lung Cancer: Current Status].
Hoffmann H, Heußel CP, Eichhorn M.
Zentralbl Chir. 2017 Sep;142(S 01):S11-S16. doi: 10.1055/s-0043-117173. Epub 2017 Sep 28. German.  PMID: 28958105 [PubMed - in process]

[Report of the Working Group on Thoracic Pathology of the German Society of Pathology 2017].
Fisseler-Eckhoff A, Warth A.
Pathologe. 2017 Sep 27. doi: 10.1007/s00292-017-0347-0. [Epub ahead of print] German. No abstract available.  PMID: 28956116 [PubMed - as supplied by publisher]
 

Woche 39

Macitentan for the treatment of inoperable chronic thromboembolic pulmonary hypertension (MERIT-1): results from the multicentre, phase 2, randomised, double-blind, placebo-controlled study.
Ghofrani HA, Simonneau G, D'Armini AM, Fedullo P, Howard LS, Jaïs X, Jenkins DP, Jing ZC, Madani MM, Martin N, Mayer E, Papadakis K, Richard D, Kim NH; MERIT study investigators. Lancet Respir Med. 2017 Sep 8. pii: S2213-2600(17)30305-3. doi: 10.1016/S2213-2600(17)30305-3. [Epub ahead of print]PMID: 28919201 [PubMed - as supplied by publisher]

Histology of non-small cell lung cancer predicts the response to stereotactic body radiotherapy.
Hörner-Rieber J, Bernhardt D, Dern J, König L, Adeberg S, Paul A, Heussel CP, Kappes J, Hoffmann H, Herth FJP, Debus J, Warth A, Rieken S.
Radiother Oncol. 2017 Sep 14. pii: S0167-8140(17)32553-7. doi: 10.1016/j.radonc.2017.08.029. [Epub ahead of print] PMID: 28919006 [PubMed - as supplied by publisher]

Endobronchial Valves for Endoscopic Lung Volume Reduction: Best Practice Recommendations from Expert Panel on Endoscopic Lung Volume Reduction.
Slebos DJ, Shah PL, Herth FJ, Valipour A.
Respiration. 2017;93(2):138-150. doi: 10.1159/000453588. Epub 2016 Dec 20. Review. PMID: 27992862 [PubMed - indexed for MEDLINE] Free PMC Article
 

Woche 38

Nintedanib with Add-on Pirfenidone in Idiopathic Pulmonary Fibrosis: Results of the INJOURNEY Trial.
Vancheri C, Kreuter M, Richeldi L, Ryerson CJ, Valeyre D, Grutters JC, Wiebe S, Stansen W, Quaresma M, Stowasser S, Wuyts WA; INJOURNEY™ trial investigators.
Am J Respir Crit Care Med. 2017 Sep 10. doi: 10.1164/rccm.201706-1301OC. [Epub ahead of print] PMID: 28889759 [PubMed - as supplied by publisher]

Randomised Phase 2 study of maintenance linsitinib (OSI-906) in combination with erlotinib compared with placebo plus erlotinib after platinum-based chemotherapy in patients with advanced non-small cell lung cancer.
Ciuleanu TE, Ahmed S, Kim JH, Mezger J, Park K, Thomas M, Chen J, Poondru S, VanTornout JM, Whitcomb D, Blackhall F.
Br J Cancer. 2017 Sep 5;117(6):757-766. doi: 10.1038/bjc.2017.226. Epub 2017 Aug 3. PMID: 28772281 [PubMed - indexed for MEDLINE]

BET-bromodomain inhibitors modulate epigenetic patterns at the diacylglycerol kinase alpha enhancer associated with radiation-induced fibrosis.
Valinciute G, Weigel C, Veldwijk MR, Oakes CC, Herskind C, Wenz F, Plass C, Schmezer P, Popanda O.
Radiother Oncol. 2017 Sep 12. pii: S0167-8140(17)32552-5. doi: 10.1016/j.radonc.2017.08.028. [Epub ahead of print] PMID: 28916223 [PubMed - as supplied by publisher]

The Modern Art of Reading Computed Tomography Images of the Lungs: Quantitative CT.
Herth FJF, Kirby M, Sieren J, Herth J, Schirm J, Wood S, Schuhmann M.
Respiration. 2017 Sep 16. doi: 10.1159/000480435. [Epub ahead of print] PMID: 28918422 [PubMed - as supplied by publisher]
 

Woche 37

A Multicenter RCT of Zephyr® Endobronchial Valve Treatment in Heterogeneous Emphysema (TRANSFORM).
Kemp SV, Slebos DJ, Kirk A, Kornaszewska M, Carron K, Ek L, Broman G, Hillerdal G, Mal H, Pison C, Briault A, Downer N, Darwiche K, Rao J, Hübner RH, Ruwwe-Glosenkamp C, Trosini-Desert V, Eberhardt R, Herth FJ, Derom E, Malfait T, Shah PL, Garner JL, Ten Hacken NH, Fallouh H, Leroy S, Marquette CH; TRANSFORM Study Team.
Am J Respir Crit Care Med. 2017 Sep 8. doi: 10.1164/rccm.201707-1327OC. [Epub ahead of print] PMID: 28885054 [PubMed - as supplied by publisher]

Texture analysis using proton density and T2 relaxation in patients with histological usual interstitial pneumonia (UIP) or nonspecific interstitial pneumonia (NSIP).
Buzan MTA, Wetscherek A, Heussel CP, Kreuter M, Herth FJ, Warth A, Kauczor HU, Pop CM, Dinkel J.
PLoS One. 2017 May 16;12(5):e0177689. doi: 10.1371/journal.pone.0177689. eCollection 2017. PMID: 28520778 [PubMed - indexed for MEDLINE] Free PMC Article

Effect of smoking cessation on quantitative computed tomography in smokers at risk in a lung cancer screening population.
Jobst BJ, Weinheimer O, Trauth M, Becker N, Motsch E, Groß ML, Tremper J, Delorme S, Eigentopf A, Eichinger M, Kauczor HU, Wielpütz MO.
Eur Radiol. 2017 Sep 7. doi: 10.1007/s00330-017-5030-6. [Epub ahead of print] PMID: 28884215 [PubMed - as supplied by publisher]

Exploring efficacy and safety of oral Pirfenidone for progressive, non-IPF lung fibrosis (RELIEF) - a randomized, double-blind, placebo-controlled, parallel group, multi-center, phase II trial.
Behr J, Neuser P, Prasse A, Kreuter M, Rabe K, Schade-Brittinger C, Wagner J, Günther A.
BMC Pulm Med. 2017 Sep 6;17(1):122. doi: 10.1186/s12890-017-0462-y. PMID: 28877715 [PubMed - in process] Free Article

RESPITE: switching to riociguat in pulmonary arterial hypertension patients with inadequate response to phosphodiesterase-5 inhibitors.
Hoeper MM, Simonneau G, Corris PA, Ghofrani HA, Klinger JR, Langleben D, Naeije R, Jansa P, Rosenkranz S, Scelsi L, Grünig E, Vizza CD, Chang M, Colorado P, Meier C, Busse D, Benza RL.
Eur Respir J. 2017 Sep 9;50(3). pii: 1602425. doi: 10.1183/13993003.02425-2016. Print 2017 Sep. PMID: 28889107 [PubMed - in process]

Current Practice of Airway Stenting in the Adult Population in Europe: A Survey of the European Association of Bronchology and Interventional Pulmonology (EABIP).
Dutau H, Breen D, Bugalho A, Dalar L, Daniels J, Dooms C, Eberhardt R, Ek L, Encheva M, Febvre M, Hackl M, Marran S, Papai-Szekely Z, Perch M, Roglic M, Rosell A, Rozman A, Shah PL, Simon M, Szlubowski A, Stratakos G, Sundset A, Uibu T, Von Garnier C, Zaric B, Zdraveska M, Zuccatosta L, Bokan D, Arshad Husain S, Bilaceroglu S, Gasche-Soccal P, Gasparini S, Herth FJF, Munavvar M.
Respiration. 2017 Sep 8. doi: 10.1159/000480152. [Epub ahead of print] PMID: 28881352 [PubMed - as supplied by publisher]
 

Woche 36

Diagnostic accuracy of a clinical diagnosis of idiopathic pulmonary fibrosis: an international case-cohort study.
Walsh SLF, Maher TM, Kolb M, Poletti V, Nusser R, Richeldi L, Vancheri C, Wilsher ML, Antoniou KM, Behr J, Bendstrup E, Brown K, Calandriello L, Corte TJ, Cottin V, Crestani B, Flaherty K, Glaspole I, Grutters J, Inoue Y, Kokosi M, Kondoh Y, Kouranos V, Kreuter M, Johannson K, Judge E, Ley B, Margaritopoulos G, Martinez FJ, Molina-Molina M, Morais A, Nunes H, Raghu G, Ryerson CJ, Selman M, Spagnolo P, Taniguchi H, Tomassetti S, Valeyre D, Wijsenbeek M, Wuyts W, Hansell D, Wells A; IPF Project Consortium.
Eur Respir J. 2017 Aug 31;50(2). pii: 1700936. doi: 10.1183/13993003.00936-2017. Print 2017 Aug. PMID: 28860269 [PubMed - in process]

Reproducibility and comparison of oxygen-enhanced T1 quantification in COPD and asthma patients.
Triphan SM, Jobst BJ, Anjorin A, Sedlaczek O, Wolf U, Terekhov M, Hoffmann C, Ley S, Düber C, Biederer J, Kauczor HU, Jakob PM, Wielpütz MO.
PLoS One. 2017 Feb 16;12(2):e0172479. doi: 10.1371/journal.pone.0172479. eCollection 2017. PMID: 28207845 [PubMed - indexed for MEDLINE] Free PMC Article

Interlaboratory-concordance of PD-L1 immunohistochemistry for non-small cell lung cancer.
Scheel AH, Baenfer G, Baretton G, Dietel M, Diezko R, Henkel T, Heukamp LC, Jasani B, Jöhrens K, Kirchner T, Lasitschka F, Petersen I, Reu S, Schildhaus HU, Schirmacher P, Schwamborn K, Sommer U, Stoss O, Tiemann M, Warth A, Weichert W, Wolf J, Büttner R, Rüschoff J.
Histopathology. 2017 Aug 29. doi: 10.1111/his.13375. [Epub ahead of print] PMID: 28851100 [PubMed - as supplied by publisher]

Identification of Ligands and Translation to Clinical Applications.
Haberkorn U, Mier W, Kopka K, Herold-Mende C, Altmann A, Babich J.
J Nucl Med. 2017 Sep;58(Suppl 2):27S-33S. doi: 10.2967/jnumed.116.186791. PMID: 28864609 [PubMed - in process]

Reflection of illness and strategies for handling advanced lung cancer - a qualitative analysis in patients and their relatives.
Sparla A, Flach-Vorgang S, Villalobos M, Krug K, Kamradt M, Coulibaly K, Szecsenyi J, Thomas M, Gusset-Bährer S, Ose D.
BMC Health Serv Res. 2017 Mar 2;17(1):173. doi: 10.1186/s12913-017-2110-x. PMID: 28253884 [PubMed - indexed for MEDLINE] Free PMC Article
 

Woche 35

Prevalence and clinical association of MET gene overexpression and amplification in patients with NSCLC: Results from the European Thoracic Oncology Platform (ETOP) Lungscape project.
Bubendorf L, Dafni U, Schöbel M, Finn SP, Tischler V, Sejda A, Marchetti A, Thunnissen E, Verbeken EK, Warth A, Sansano I, Cheney R, Speel EJM, Nonaka D, Monkhorst K, Hager H, Martorell M, Savic S, Kerr KM, Tan Q, Tsourti Z, Geiger TR, Kammler R, Schulze K, Das-Gupta A, Shames D, Peters S, Stahel RA; Lungscape Consortium.
Lung Cancer. 2017 Sep;111:143-149. doi: 10.1016/j.lungcan.2017.07.021. Epub 2017 Jul 22. PMID: 28838386 [PubMed - in process]

Coil therapy for patients with severe emphysema and bilateral incomplete fissures - effectiveness and complications after 1-year follow-up: a single-center experience.
Kontogianni K, Gerovasili V, Gompelmann D, Schuhmann M, Hoffmann H, Heussel CP, Herth FJ, Eberhardt R.
Int J Chron Obstruct Pulmon Dis. 2017 Jan 23;12:383-394. doi: 10.2147/COPD.S117655. eCollection 2017. PMID: 28176954 [PubMed - indexed for MEDLINE] Free PMC Article
 

Woche 34

Prevalence of somatic mitochondrial mutations and spatial distribution of mitochondria in non-small cell lung cancer.
Kazdal D, Harms A, Endris V, Penzel R, Kriegsmann M, Eichhorn F, Muley T, Stenzinger A, Pfarr N, Weichert W, Warth A.
Br J Cancer. 2017 Jul 11;117(2):220-226. doi: 10.1038/bjc.2017.155. Epub 2017 May 30. PMID: 28557978 [PubMed - indexed for MEDLINE]

Targeting RET in Patients With RET-Rearranged Lung Cancers: Results From the Global, Multicenter RET Registry.
Gautschi O, Milia J, Filleron T, Wolf J, Carbone DP, Owen D, Camidge R, Narayanan V, Doebele RC, Besse B, Remon-Masip J, Janne PA, Awad MM, Peled N, Byoung CC, Karp DD, Van Den Heuvel M, Wakelee HA, Neal JW, Mok TSK, Yang JCH, Ou SI, Pall G, Froesch P, Zalcman G, Gandara DR, Riess JW, Velcheti V, Zeidler K, Diebold J, Früh M, Michels S, Monnet I, Popat S, Rosell R, Karachaliou N, Rothschild SI, Shih JY, Warth A, Muley T, Cabillic F, Mazières J, Drilon A.
J Clin Oncol. 2017 May 1;35(13):1403-1410. doi: 10.1200/JCO.2016.70.9352. Epub 2017 Mar 13. PMID: 28447912 [PubMed - indexed for MEDLINE]

OTP: An automatized system for managing and processing NGS data.
Reisinger E, Genthner L, Kerssemakers J, Kensche P, Borufka S, Jugold A, Kling A, Prinz M, Scholz I, Zipprich G, Eils R, Lawerenz C, Eils J.
J Biotechnol. 2017 Aug 10. pii: S0168-1656(17)31592-4. doi: 10.1016/j.jbiotec.2017.08.006. [Epub ahead of print] PMID: 28803971 [PubMed - as supplied by publisher]

Three-center feasibility of lung clearance index in infants and preschool children with cystic fibrosis and other lung diseases.
Stahl M, Graeber SY, Joachim C, Barth S, Ricklefs I, Diekmann G, Kopp MV, Naehrlich L, Mall MA.
J Cyst Fibros. 2017 Aug 12. pii: S1569-1993(17)30836-6. doi: 10.1016/j.jcf.2017.08.001. [Epub ahead of print] PMID: 28811149 [PubMed - as supplied by publisher]

Endoscopic Lung Volume Reduction: An Expert Panel Recommendation - Update 2017.
Herth FJF, Slebos DJ, Criner GJ, Shah PL.
Respiration. 2017 Aug 18. doi: 10.1159/000479379. [Epub ahead of print] PMID: 28817821 [PubMed - as supplied by publisher]

Computed Tomography: The Better Pulmonologist?
Herth FJF, Schuhmann M.
Respiration. 2017 Aug 18. doi: 10.1159/000479332. [Epub ahead of print] No abstract available.  PMID: 28817818 [PubMed - as supplied by publisher]
 

Woche 33

Safety and Efficacy of Immunoadsorption as an Add-On to Medical Treatment in Patients with Severe Idiopathic Pulmonary Arterial Hypertension.
Nagel C, Ewert R, Egenlauf B, Lehmkuhl HB, Rosenkranz S, Benjamin N, Schwenger V, Herth FJF, Grünig E.
Respiration. 2017 Aug 5;94(3):263-271. doi: 10.1159/000478744. [Epub ahead of print] PMID: 28787715 [PubMed - as supplied by publisher]

Cardiopulmonary exercise testing for detecting pulmonary arterial hypertension in systemic sclerosis.
Dumitrescu D, Nagel C, Kovacs G, Bollmann T, Halank M, Winkler J, Hellmich M, Grünig E, Olschewski H, Ewert R, Rosenkranz S.
Heart. 2017 May;103(10):774-782. doi: 10.1136/heartjnl-2016-309981. Epub 2017 Jan 6. PMID: 28062514 [PubMed - indexed for MEDLINE]

Clinical and radiological outcome following pneumothorax after endoscopic lung volume reduction with valves.
Gompelmann D, Benjamin N, Kontogianni K, Herth F, Heussel CP, Hoffmann H, Eberhardt R.
Int J Chron Obstruct Pulmon Dis. 2016 Dec 7;11:3093-3099. eCollection 2016. PMID: 27994448 [PubMed - indexed for MEDLINE] Free PMC Article

Predictors of pneumothorax following endoscopic valve therapy in patients with severe emphysema.
Gompelmann D, Lim HJ, Eberhardt R, Gerovasili V, Herth FJ, Heussel CP, Eichinger M.
Int J Chron Obstruct Pulmon Dis. 2016 Aug 1;11:1767-73. doi: 10.2147/COPD.S106439. eCollection 2016. PMID: 27536088 [PubMed - indexed for MEDLINE] Free PMC Article

Significant lung volume reduction with endobronchial valves in a patient despite the presence of microcollaterals masked by low-flow Chartis phenotype.
Yin Y, Hou G, Herth FJ, Wang XB, Wang QY, Kang J.
Int J Chron Obstruct Pulmon Dis. 2016 Nov 24;11:2913-2917. eCollection 2016. PMID: 27920518 [PubMed - indexed for MEDLINE] Free PMC Article

Prognostic Impact of CT-Quantified Muscle and Fat Distribution before and after First-Line-Chemotherapy in Lung Cancer Patients.
Nattenmüller J, Wochner R, Muley T, Steins M, Hummler S, Teucher B, Wiskemann J, Kauczor HU, Wielpütz MO, Heussel CP.
PLoS One. 2017 Jan 20;12(1):e0169136. doi: 10.1371/journal.pone.0169136. eCollection 2017. PMID: 28107410 [PubMed - indexed for MEDLINE] Free PMC Article

Remote ischemic preconditioning does not prevent acute mountain sickness after rapid ascent to 3450 m.
Berger MM, Macholz F, Lehmann L, Dankl D, Hochreiter M, Bacher B, Bärtsch P, Mairbäurl H.
J Appl Physiol (1985). 2017 Aug 10:jap.00505.2017. doi: 10.1152/japplphysiol.00505.2017. [Epub ahead of print] PMID: 28798201 [PubMed - as supplied by publisher]

Pathway-Based Kernel Boosting for the Analysis of Genome-Wide Association Studies.
Friedrichs S, Manitz J, Burger P, Amos CI, Risch A, Chang-Claude J, Wichmann HE, Kneib T, Bickeböller H, Hofner B.
Comput Math Methods Med. 2017;2017:6742763. doi: 10.1155/2017/6742763. Epub 2017 Jul 13. PMID: 28785300 [PubMed - in process] Free PMC Article

Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues.
Delacher M, Imbusch CD, Weichenhan D, Breiling A, Hotz-Wagenblatt A, Träger U, Hofer AC, Kägebein D, Wang Q, Frauhammer F, Mallm JP, Bauer K, Herrmann C, Lang PA, Brors B, Plass C, Feuerer M.
Nat Immunol. 2017 Aug 7. doi: 10.1038/ni.3799. [Epub ahead of print] PMID: 28783152
 

Woche 32

Comparison of Lung Clearance Index and Magnetic Resonance Imaging for Assessment of Lung Disease in Children with Cystic Fibrosis.
Stahl M, Wielpütz MO, Graeber SY, Joachim C, Sommerburg O, Kauczor HU, Puderbach M, Eichinger M, Mall MA.
Am J Respir Crit Care Med. 2017 Feb 1;195(3):349-359. doi: 10.1164/rccm.201604-0893OC. PMID: 27575911 [PubMed - indexed for MEDLINE]

Randomised Phase 2 study of maintenance linsitinib (OSI-906) in combination with erlotinib compared with placebo plus erlotinib after platinum-based chemotherapy in patients with advanced non-small cell lung cancer.
Ciuleanu TE, Ahmed S, Kim JH, Mezger J, Park K, Thomas M, Chen J, Poondru S, VanTornout JM, Whitcomb D, Blackhall F.
Br J Cancer. 2017 Aug 3. doi: 10.1038/bjc.2017.226. [Epub ahead of print] PMID: 28772281 [PubMed - as supplied by publisher]

Low Input Whole-Exome Sequencing to Determine the Representation of the Tumor Exome in Circulating DNA of Non-Small Cell Lung Cancer Patients.
Dietz S, Schirmer U, Mercé C, von Bubnoff N, Dahl E, Meister M, Muley T, Thomas M, Sültmann H.
PLoS One. 2016 Aug 16;11(8):e0161012. doi: 10.1371/journal.pone.0161012. eCollection 2016. PMID: 27529345 [PubMed - indexed for MEDLINE] Free PMC Article

Mortality in pulmonary arterial hypertension: prediction by the 2015 European pulmonary hypertension guidelines risk stratification model.
Hoeper MM, Kramer T, Pan Z, Eichstaedt CA, Spiesshoefer J, Benjamin N, Olsson KM, Meyer K, Vizza CD, Vonk-Noordegraaf A, Distler O, Opitz C, Gibbs JSR, Delcroix M, Ghofrani HA, Huscher D, Pittrow D, Rosenkranz S, Grünig E.
Eur Respir J. 2017 Aug 3;50(2). pii: 1700740. doi: 10.1183/13993003.00740-2017. Print 2017 Aug. PMID: 28775047 [PubMed - in process]

Automated 3D Volumetry of the Pulmonary Arteries based on Magnetic Resonance Angiography Has Potential for Predicting Pulmonary Hypertension.
Rengier F, Wörz S, Melzig C, Ley S, Fink C, Benjamin N, Partovi S, von Tengg-Kobligk H, Rohr K, Kauczor HU, Grünig E.
PLoS One. 2016 Sep 14;11(9):e0162516. doi: 10.1371/journal.pone.0162516. eCollection 2016. PMID: 27626802 [PubMed - indexed for MEDLINE] Free PMC Article

Influence of exposure parameters and iterative reconstruction on automatic airway segmentation and analysis on MDCT-An ex vivo phantom study.
Leutz-Schmidt P, Weinheimer O, Jobst BJ, Dinkel J, Biederer J, Kauczor HU, Puderbach MU, Wielpütz MO.
PLoS One. 2017 Aug 2;12(8):e0182268. doi: 10.1371/journal.pone.0182268. eCollection 2017. PMID: 28767732 [PubMed - in process] Free Article

[Expert Knowledge and Supporting Advice for the Clinical Use of Nintedanib in Patients with Idiopathic Pulmonary Fibrosis].
Behr J, Günther A, Kreuter M, Koschel D, Prasse A, Pfeifer M, Costabel U.
Pneumologie. 2017 Aug 3. doi: 10.1055/s-0043-109856. [Epub ahead of print] German.  PMID: 28772332 [PubMed - as supplied by publisher]
 

Woche 31

Haemodynamic effects of riociguat in inoperable/recurrent chronic thromboembolic pulmonary hypertension.
Kim NH, D'Armini AM, Grimminger F, Grünig E, Hoeper MM, Jansa P, Mayer E, Neurohr C, Simonneau G, Torbicki A, Wang C, Fritsch A, Davie N, Ghofrani HA.
Heart. 2017 Apr;103(8):599-606. doi: 10.1136/heartjnl-2016-309621. Epub 2016 Dec 23. PMID: 28011757 [PubMed - indexed for MEDLINE] Free Article

Prognosis and longitudinal changes of physical activity in idiopathic pulmonary fibrosis.
Bahmer T, Kirsten AM, Waschki B, Rabe KF, Magnussen H, Kirsten D, Gramm M, Hummler S, Brunnemer E, Kreuter M, Watz H.
BMC Pulm Med. 2017 Jul 25;17(1):104. doi: 10.1186/s12890-017-0444-0. PMID: 28743305 [PubMed - in process] Free Article

Motion monitoring during a course of lung radiotherapy with anchored electromagnetic transponders : Quantification of inter- and intrafraction motion and variability of relative transponder positions.
Schmitt D, Nill S, Roeder F, Gompelmann D, Herth F, Oelfke U.
Strahlenther Onkol. 2017 Jul 21. doi: 10.1007/s00066-017-1183-0. [Epub ahead of print] PMID: 28733724 [PubMed - as supplied by publisher]

Systemic therapy treatment patterns in patients with advanced non-small cell lung cancer (NSCLC): PIvOTAL study.
de Castro J, Tagliaferri P, de Lima VCC, Ng S, Thomas M, Arunachalam A, Cao X, Kothari S, Burke T, Myeong H, Grattan A, Lee DH.
Eur J Cancer Care (Engl). 2017 Jul 27. doi: 10.1111/ecc.12734. [Epub ahead of print] PMID: 28748556 [PubMed - as supplied by publisher]
 

Woche 30

Motion monitoring during a course of lung radiotherapy with anchored electromagnetic transponders : Quantification of inter- and intrafraction motion and variability of relative transponder positions.
Schmitt D, Nill S, Roeder F, Gompelmann D, Herth F, Oelfke U.
Strahlenther Onkol. 2017 Jul 21. doi: 10.1007/s00066-017-1183-0. [Epub ahead of print] PMID: 28733724 [PubMed - as supplied by publisher]

Bronchoscopy in lung cancer: navigational modalities and their clinical use.
Herth FJ, Eberhardt R, Schuhmann M.
Expert Rev Respir Med. 2016 Aug;10(8):901-6. doi: 10.1080/17476348.2016.1191354. Epub 2016 Jun 3. Review. PMID: 27196405 [PubMed - indexed for MEDLINE]

Bronchoscopy and bleeding risk.
Herth FJF.
Eur Respir Rev. 2017 Jul 19;26(145). pii: 170052. doi: 10.1183/16000617.0052-2017. Print 2017 Sep 30. No abstract available. PMID: 28724564 [PubMed - in process] Free Article

Synonymous EGFR variant p.Q787Q is neither prognostic nor predictive in patients with lung adenocarcinoma.
Leichsenring J, Volckmar AL, Magios N, Morais de Oliveira CM, Penzel R, Brandt R, Kirchner M, Bozorgmehr F, Thomas M, Schirmacher P, Warth A, Endris V, Stenzinger A.
Genes Chromosomes Cancer. 2017 Mar;56(3):214-220. doi: 10.1002/gcc.22427. Epub 2016 Nov 30. PMID: 27750395 [PubMed - indexed for MEDLINE]
 

Woche 29

Spatial distribution of EGFR and KRAS mutation frequencies correlates with histological growth patterns of lung adenocarcinomas.
Dietz S, Harms A, Endris V, Eichhorn F, Kriegsmann M, Longuespée R, Stenzinger A, Sültmann H, Warth A, Kazdal D.
Int J Cancer. 2017 Jul 12. doi: 10.1002/ijc.30881. [Epub ahead of print] PMID: 28699162 [PubMed - as supplied by publisher]

Health related quality of life in patients with idiopathic pulmonary fibrosis in clinical practice: insights-IPF registry.
Kreuter M, Swigris J, Pittrow D, Geier S, Klotsche J, Prasse A, Wirtz H, Koschel D, Andreas S, Claussen M, Grohé C, Wilkens H, Hagmeyer L, Skowasch D, Meyer JF, Kirschner J, Gläser S, Herth FJF, Welte T, Neurohr C, Schwaiblmair M, Held M, Bahmer T, Frankenberger M, Behr J.
Respir Res. 2017 Jul 14;18(1):139. doi: 10.1186/s12931-017-0621-y.PMID: 28709421 [PubMed - in process] Free Article

Blood Eosinophils and Response to Maintenance Chronic Obstructive Pulmonary Disease Treatment. Data from the FLAME Trial.
Roche N, Chapman KR, Vogelmeier CF, Herth FJF, Thach C, Fogel R, Olsson P, Patalano F, Banerji D, Wedzicha JA.
Am J Respir Crit Care Med. 2017 May 1;195(9):1189-1197. doi: 10.1164/rccm.201701-0193OC. PMID: 28278391 [PubMed - indexed for MEDLINE]

Bronchoscopic Transparenchymal Nodule Access: Feasibility and Safety in an Endoscopic Unit.
Harzheim D, Sterman D, Shah PL, Eberhardt R, Herth FJ.
Respiration. 2016;91(4):302-6. doi: 10.1159/000445032. Epub 2016 Mar 24. PMID: 27007334 [PubMed - indexed for MEDLINE]

[Health Science Research with Primary Care Routine Data From Electronic Patient Records: the BeoNet Registry].
Lingner H, Aumann I, Wacker M, Kreuter M, Leidl R, von der Schulenburg JG, Welte T.
Gesundheitswesen. 2017 Jul 11. doi: 10.1055/s-0043-108544. [Epub ahead of print] German.  PMID: 28697524 [PubMed - as supplied by publisher]

Rehabilitation in patients with pulmonary arterial hypertension.
Keusch S, Turk A, Saxer S, Ehlken N, Grunig E, Ulrich S, On Behalf Of The Swiss Society Of Pulmonary Hypertension.
Swiss Med Wkly. 2017 Jul 11;147:w14462. doi: smw.2017.14462. eCollection 2017 Jul 11. PMID: 28695558 [PubMed - in process] Free Article
 

Woche 28

First identification of <i>Krüppel-like factor 2</i> mutation in heritable pulmonary arterial hypertension.
Eichstaedt CA, Song J, Viales RR, Pan Z, Benjamin N, Fischer C, Hoeper MM, Ulrich S, Hinderhofer K, Grünig E.
Clin Sci (Lond). 2017 Apr 25;131(8):689-698. doi: 10.1042/CS20160930. Epub 2017 Feb 10. PMID: 28188237 [PubMed - indexed for MEDLINE]

Endobronchial Valve Therapy in Patients with Homogeneous Emphysema. Results from the IMPACT Study.
Valipour A, Slebos DJ, Herth F, Darwiche K, Wagner M, Ficker JH, Petermann C, Hubner RH, Stanzel F, Eberhardt R; IMPACT Study Team.
Am J Respir Crit Care Med. 2016 Nov 1;194(9):1073-1082. PMID: 27580428 [PubMed - indexed for MEDLINE]

Navigation Bronchoscopy-Guided Radiofrequency Ablation for Nonsurgical Peripheral Pulmonary Tumors.
Xie F, Zheng X, Xiao B, Han B, Herth FJF, Sun J.
Respiration. 2017 Jul 6. doi: 10.1159/000477764. [Epub ahead of print] PMID: 28683443 [PubMed - as supplied by publisher]

[German Guideline for Idiopathic Pulmonary Fibrosis - Update on Pharmacological Therapies 2017].
Behr J, Günther A, Bonella F, Geißler K, Koschel D, Kreuter M, Prasse A, Schönfeld N, Sitter H, Müller-Quernheim J, Costabel U.
Pneumologie. 2017 Jul 5. doi: 10.1055/s-0043-115504. [Epub ahead of print] German. No abstract available.  PMID: 28679139 [PubMed - as supplied by publisher]
 

Woche 27

Antacid therapy in idiopathic pulmonary fibrosis: more questions than answers?
Johannson KA, Strâmbu I, Ravaglia C, Grutters JC, Valenzuela C, Mogulkoc N, Luppi F, Richeldi L, Wells AU, Vancheri C, Kreuter M; Erice ILD Working Group.
Lancet Respir Med. 2017 Jul;5(7):591-598. doi: 10.1016/S2213-2600(17)30219-9. Review. PMID: 28664861 [PubMed - in process]

Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas.
Campbell JD, Alexandrov A, Kim J, Wala J, Berger AH, Pedamallu CS, Shukla SA, Guo G, Brooks AN, Murray BA, Imielinski M, Hu X, Ling S, Akbani R, Rosenberg M, Cibulskis C, Ramachandran A, Collisson EA, Kwiatkowski DJ, Lawrence MS, Weinstein JN, Verhaak RG, Wu CJ, Hammerman PS, Cherniack AD, Getz G; Cancer Genome Atlas Research Network, Artyomov MN, Schreiber R, Govindan R, Meyerson M.
Nat Genet. 2016 Jun;48(6):607-16. doi: 10.1038/ng.3564. Epub 2016 May 9.
PMID: 27158780 [PubMed - indexed for MEDLINE] Free PMC Article

An individual-based model for collective cancer cell migration explains speed dynamics and phenotype variability in response to growth factors.
Stichel D, Middleton AM, Müller BF, Depner S, Klingmüller U, Breuhahn K, Matthäus F.
NPJ Syst Biol Appl. 2017 Mar 3;3:5. doi: 10.1038/s41540-017-0006-3. eCollection 2017. PMID: 28649432 [PubMed - in process] Free PMC Article

Pre-Capillary, Combined, and Post-Capillary Pulmonary Hypertension: A Pathophysiological Continuum.
Opitz CF, Hoeper MM, Gibbs JS, Kaemmerer H, Pepke-Zaba J, Coghlan JG, Scelsi L, D'Alto M, Olsson KM, Ulrich S, Scholtz W, Schulz U, Grünig E, Vizza CD, Staehler G, Bruch L, Huscher D, Pittrow D, Rosenkranz S.
J Am Coll Cardiol. 2016 Jul 26;68(4):368-78. doi: 10.1016/j.jacc.2016.05.047. PMID: 27443433 [PubMed - indexed for MEDLINE] Free Articl
 

Woche 26

Cellular distribution and function of ion channels involved in transport processes in rat tracheal epithelium.
Hahn A, Faulhaber J, Srisawang L, Stortz A, Salomon JJ, Mall MA, Frings S, Möhrlen F.
Physiol Rep. 2017 Jun;5(12). pii: e13290. doi: 10.14814/phy2.13290. PMID: 28642338 [PubMed - in process] Free Article

Simultaneous quantification of endothelin receptor antagonists and phosphodiesterase 5 inhibitors currently used in pulmonary arterial hypertension.
Enderle Y, Witt L, Wilkens H, Grünig E, Haefeli WE, Burhenne J.
J Pharm Biomed Anal. 2017 Jun 10;143:291-298. doi: 10.1016/j.jpba.2017.05.052. [Epub ahead of print] PMID: 28628863 [PubMed - as supplied by publisher]

A randomized, phase 2 evaluation of the CHK1 inhibitor, LY2603618, administered in combination with pemetrexed and cisplatin in patients with advanced nonsquamous non-small cell lung cancer.
Wehler T, Thomas M, Schumann C, Bosch-Barrera J, Viñolas Segarra N, Dickgreber NJ, Dalhoff K, Sebastian M, Corral Jaime J, Alonso M, Hynes SM, Lin J, Hurt K, Bence Lin A, Calvo E, Paz-Ares L.
Lung Cancer. 2017 Jun;108:212-216. doi: 10.1016/j.lungcan.2017.03.001. Epub 2017 Mar 6. PMID: 28625637 [PubMed - in process]
 

Woche 25

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
McKay JD, Hung RJ, Han Y, Zong X, Carreras-Torres R, Christiani DC, Caporaso NE, Johansson M, Xiao X, Li Y, Byun J, Dunning A, Pooley KA, Qian DC, Ji X, Liu G, Timofeeva MN, Bojesen SE, Wu X, Le Marchand L, Albanes D, Bickeböller H, Aldrich MC, Bush WS, Tardon A, Rennert G, Teare MD, Field JK, Kiemeney LA, Lazarus P, Haugen A, Lam S, Schabath MB, Andrew AS, Shen H, Hong YC, Yuan JM, Bertazzi PA, Pesatori AC, Ye Y, Diao N, Su L, Zhang R, Brhane Y, Leighl N, Johansen JS, Mellemgaard A, Saliba W, Haiman CA, Wilkens LR, Fernandez-Somoano A, Fernandez-Tardon G, van der Heijden HFM, Kim JH, Dai J, Hu Z, Davies MPA, Marcus MW, Brunnström H, Manjer J, Melander O, Muller DC, Overvad K, Trichopoulou A, Tumino R, Doherty JA, Barnett MP, Chen C, Goodman GE, Cox A, Taylor F, Woll P, Brüske I, Wichmann HE, Manz J, Muley TR, Risch A, Rosenberger A, Grankvist K, Johansson M, Shepherd FA, Tsao MS, Arnold SM, Haura EB, Bolca C, Holcatova I, Janout V, Kontic M, Lissowska J, Mukeria A, Ognjanovic S, Orlowski TM, Scelo G, Swiatkowska B, Zaridze D, Bakke P, Skaug V, Zienolddiny S, Duell EJ, Butler LM, Koh WP, Gao YT, Houlston RS, McLaughlin J, Stevens VL, Joubert P, Lamontagne M, Nickle DC, Obeidat M, Timens W, Zhu B, Song L, Kachuri L, Artigas MS, Tobin MD, Wain LV; SpiroMeta Consortium, Rafnar T, Thorgeirsson TE, Reginsson GW, Stefansson K, Hancock DB, Bierut LJ, Spitz MR, Gaddis NC, Lutz SM, Gu F, Johnson EO, Kamal A, Pikielny C, Zhu D, Lindströem S, Jiang X, Tyndale RF, Chenevix-Trench G, Beesley J, Bossé Y, Chanock S, Brennan P, Landi MT, Amos CI.
Nat Genet. 2017 Jun 12. doi: 10.1038/ng.3892. [Epub ahead of print] PMID: 28604730 [PubMed - as supplied by publisher]

A Prospective Study of Loose Tissue Fragments in Non-Small Cell Lung Cancer Resection Specimens: An Alternative View to "Spread Through Air Spaces".
Blaauwgeers H, Flieder D, Warth A, Harms A, Monkhorst K, Witte B, Thunnissen E.
Am J Surg Pathol. 2017 Jun 15. doi: 10.1097/PAS.0000000000000889. [Epub ahead of print] PMID: 28622180 [PubMed - as supplied by publisher]

Antifibrotic drugs as treatment of nonidiopathic pulmonary fibrosis interstitial pneumonias: the time is now (?).
Kreuter M, Wälscher J, Behr J.
Curr Opin Pulm Med. 2017 Jun 15. doi: 10.1097/MCP.0000000000000408. [Epub ahead of print] PMID: 28622199 [PubMed - as supplied by publisher]

DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats.
Brocks D, Schmidt CR, Daskalakis M, Jang HS, Shah NM, Li D, Li J, Zhang B, Hou Y, Laudato S, Lipka DB, Schott J, Bierhoff H, Assenov Y, Helf M, Ressnerova A, Islam MS, Lindroth AM, Haas S, Essers M, Imbusch CD, Brors B, Oehme I, Witt O, Lübbert M, Mallm JP, Rippe K, Will R, Weichenhan D, Stoecklin G, Gerhäuser C, Oakes CC, Wang T, Plass C.
Nat Genet. 2017 Jun 12. doi: 10.1038/ng.3889. [Epub ahead of print] PMID: 28604729 [PubMed - as supplied by publisher]
 

Woche 24

Cigarette smoke causes acute airway disease and exacerbates chronic obstructive lung disease in neonatal mice.
Jia J, Conlon TM, Ballester Lopez C, Seimetz M, Bednorz M, Zhou-Suckow Z, Weissmann N, Eickelberg O, Mall MA, Yildirim AÖ.
Am J Physiol Lung Cell Mol Physiol. 2016 Sep 1;311(3):L602-10. doi: 10.1152/ajplung.00124.2016. Epub 2016 Jul 22. PMID: 27448665 [PubMed - indexed for MEDLINE]

Prevalence of somatic mitochondrial mutations and spatial distribution of mitochondria in non-small cell lung cancer.
Kazdal D, Harms A, Endris V, Penzel R, Kriegsmann M, Eichhorn F, Muley T, Stenzinger A, Pfarr N, Weichert W, Warth A.
Br J Cancer. 2017 May 30. doi: 10.1038/bjc.2017.155. [Epub ahead of print] PMID: 28557978 [PubMed - as supplied by publisher]

Outcome and prognostic factors in patients with brain metastases from small-cell lung cancer treated with whole brain radiotherapy.
Bernhardt D, Adeberg S, Bozorgmehr F, Opfermann N, Hoerner-Rieber J, König L, Kappes J, Thomas M, Herth F, Heußel CP, Warth A, Debus J, Steins M, Rieken S.
J Neurooncol. 2017 May 30. doi: 10.1007/s11060-017-2510-0. [Epub ahead of print] PMID: 28560661 [PubMed - as supplied by publisher]

Activity and safety of ceritinib in patients with ALK-rearranged non-small-cell lung cancer (ASCEND-1): updated results from the multicentre, open-label, phase 1 trial.
Kim DW, Mehra R, Tan DS, Felip E, Chow LQ, Camidge DR, Vansteenkiste J, Sharma S, De Pas T, Riely GJ, Solomon BJ, Wolf J, Thomas M, Schuler M, Liu G, Santoro A, Sutradhar S, Li S, Szczudlo T, Yovine A, Shaw AT.
Lancet Oncol. 2016 Apr;17(4):452-63. doi: 10.1016/S1470-2045(15)00614-2. Epub 2016 Mar 11. PMID: 26973324 [PubMed - indexed for MEDLINE] Free PMC Article

Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study.
Carreras-Torres R, Johansson M, Haycock PC, Wade KH, Relton CL, Martin RM, Davey Smith G, Albanes D, Aldrich MC, Andrew A, Arnold SM, Bickeböller H, Bojesen SE, Brunnström H, Manjer J, Brüske I, Caporaso NE, Chen C, Christiani DC, Christian WJ, Doherty JA, Duell EJ, Field JK, Davies MPA, Marcus MW, Goodman GE, Grankvist K, Haugen A, Hong YC, Kiemeney LA, van der Heijden EHFM, Kraft P, Johansson MB, Lam S, Landi MT, Lazarus P, Le Marchand L, Liu G, Melander O, Park SL, Rennert G, Risch A, Haura EB, Scelo G, Zaridze D, Mukeriya A, Savić M, Lissowska J, Swiatkowska B, Janout V, Holcatova I, Mates D, Schabath MB, Shen H, Tardon A, Teare MD, Woll P, Tsao MS, Wu X, Yuan JM, Hung RJ, Amos CI, McKay J, Brennan P. PLoS One. 2017 Jun 8;12(6):e0177875. doi: 10.1371/journal.pone.0177875. eCollection 2017. PMID: 28594918 [PubMed - in process] Free Article

The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR.
Scharaw S, Iskar M, Ori A, Boncompain G, Laketa V, Poser I, Lundberg E, Perez F, Beck M, Bork P, Pepperkok R. J Cell Biol. 2016 Nov 21;215(4):543-558. Epub 2016 Nov 8. PMID: 27872256 [PubMed - indexed for MEDLINE] Free PMC Article

Precision Oncology Based on Omics Data: The NCT Heidelberg Experience.
Horak P, Klink B, Heining C, Gröschel S, Hutter B, Fröhlich M, Uhrig S, Hübschmann D, Schlesner M, Eils R, Richter D, Pfütze K, Geörg C, Meißburger B, Wolf S, Schulz A, Penzel R, Herpel E, Kirchner M, Lier A, Endris V, Singer S, Schirmacher P, Weichert W, Stenzinger A, Schlenk RF, Schröck E, Brors B, von Kalle C, Glimm H, Fröhling S.
Int J Cancer. 2017 Jun 9. doi: 10.1002/ijc.30828. [Epub ahead of print] PMID: 28597939 [PubMed - as supplied by publisher]

[German Guideline for Idiopathic Pulmonary Fibrosis - Update on Pharmacological Therapies 2017].
Behr J, Günther A, Bonella F, Geißler K, Koschel D, Kreuter M, Prasse A, Schönfeld N, Sitter H, Müller-Quernheim J, Costabel U.
Pneumologie. 2017 May 30. doi: 10.1055/s-0043-106160. [Epub ahead of print] German.  PMID: 28558396 [PubMed - as supplied by publisher]
 

Woche 22

Everolimus with paclitaxel and carboplatin as first-line treatment for metastatic large-cell neuroendocrine lung carcinoma: a multicenter phase II trial.
Christopoulos P, Engel-Riedel W, Grohé C, Kropf-Sanchen C, von Pawel J, Gütz S, Kollmeier J, Eberhardt W, Ukena D, Baum V, Nimmrich I, Sieder C, Schnabel PA, Serke M, Thomas M. Ann Oncol. 2017 May 23. doi: 10.1093/annonc/mdx268. [Epub ahead of print] PMID: 28535181
 

Woche 21

Texture analysis using proton density and T2 relaxation in patients with histological usual interstitial pneumonia (UIP) or nonspecific interstitial pneumonia (NSIP).
Buzan MTA, Wetscherek A, Heussel CP, Kreuter M, Herth FJ, Warth A, Kauczor HU, Pop CM, Dinkel J.
PLoS One. 2017 May 16;12(5):e0177689. doi: 10.1371/journal.pone.0177689. eCollection 2017. PMID: 28520778 [PubMed - in process] Free Article

Airway mucus, inflammation and remodeling: emerging links in the pathogenesis of chronic lung diseases.
Zhou-Suckow Z, Duerr J, Hagner M, Agrawal R, Mall MA.
Cell Tissue Res. 2017 Mar;367(3):537-550. doi: 10.1007/s00441-016-2562-z. Epub 2017 Jan 20. Review. PMID: 28108847 [PubMed - indexed for MEDLINE]

Flexible 19-Gauge Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration Needle: First Experience.
Tyan C, Patel P, Czarnecka K, Gompelmann D, Eberhardt R, Fortin M, MacEachern P, Hergott CA, Dumoulin E, Tremblay A, Kemp SV, Shah PL, Herth FJF, Yasufuku K.
Respiration. 2017 May 17. doi: 10.1159/000475504. [Epub ahead of print] PMID: 28511175 [PubMed - as supplied by publisher]
 

Woche 20

Disruption of the Hepcidin/Ferroportin Regulatory System Causes Pulmonary Iron Overload and Restrictive Lung Disease.
Neves J, Leitz D, Kraut S, Brandenberger C, Agrawal R, Weissmann N, Mühlfeld C, Mall MA, Altamura S, Muckenthaler MU.
EBioMedicine. 2017 Apr 29. pii: S2352-3964(17)30191-3. doi: 10.1016/j.ebiom.2017.04.036. [Epub ahead of print] PMID: 28499927 [PubMed - as supplied by publisher] Free Article

Plasma Drug Concentrations in Patients with Pulmonary Arterial Hypertension on Combination Treatment.
Grünig E, Ohnesorge J, Benjamin N, Burhenne J, Enderle Y, Egenlauf B, Fischer C, Harutyunova S, Huppertz A, Klose H, Haefeli WE.
Respiration. 2017 May 12. doi: 10.1159/000470916. [Epub ahead of print] PMID: 28494463 [PubMed - as supplied by publisher]
 

Woche 19

Tumor cell load and heterogeneity estimation from diffusion-weighted MRI calibrated with histological data: an example from lung cancer.
Yin Y, Sedlaczek O, Muller B, Warth A, Gonzalez-Vallinas M, Grabe N, Kauczor HU, Breuhahn K, Vignon-Clemental I, Drasdo D.
IEEE Trans Med Imaging. 2017 Apr 27. doi: 10.1109/TMI.2017.2698525. [Epub ahead of print]
PMID: 28463188 [PubMed - as supplied by publisher]

Identification of a Novel ITGavb6-Binding Peptide Using Protein Separation and Phage Display.
Altmann A, Sauter M, Roesch S, Mier W, Warta R, Debus J, Dyckhoff G, Herold-Mende C, Haberkorn U.
Clin Cancer Res. 2017 Aug 1;23(15):4170-4180. doi: 10.1158/1078-0432.CCR-16-3217. Epub 2017 May 3.

Evaluation of the pharmacoDYNAMIC effects of riociguat in subjects with pulmonary hypertension and heart failure with preserved ejection fraction : Study protocol for a randomized controlled trial.
Mascherbauer J, Grünig E, Halank M, Hohenforst-Schmidt W, Kammerlander AA, Pretsch I, Steringer-Mascherbauer R, Ulrich S, Lang IM, Wargenau M, Frey R, Bonderman D.
Wien Klin Wochenschr. 2016 Dec;128(23-24):882-889. Epub 2016 Sep 2. PMID: 27590259 [PubMed - indexed for MEDLINE] Free PMC Article

Clinical highlights from the 2016 European Respiratory Society International Congress.
Kahn N, Fregonese L, Barrecheguren M, Franssen FME, Grgic A, Gompelmann D, Bibaki E, Antoniou KM, Kocks JWH, Pinnock H, Herth F.
ERJ Open Res. 2017 Apr 12;3(2). pii: 00147-2016. doi: 10.1183/23120541.00147-2016. eCollection 2017 Apr. PMID: 28462234 [PubMed - in process] Free PMC Article
 

Woche 18

Targeting RET in Patients With RET-Rearranged Lung Cancers: Results From the Global, Multicenter RET Registry.
Gautschi O, Milia J, Filleron T, Wolf J, Carbone DP, Owen D, Camidge R, Narayanan V, Doebele RC, Besse B, Remon-Masip J, Janne PA, Awad MM, Peled N, Byoung CC, Karp DD, Van Den Heuvel M, Wakelee HA, Neal JW, Mok TSK, Yang JCH, Ou SI, Pall G, Froesch P, Zalcman G, Gandara DR, Riess JW, Velcheti V, Zeidler K, Diebold J, Früh M, Michels S, Monnet I, Popat S, Rosell R, Karachaliou N, Rothschild SI, Shih JY, Warth A, Muley T, Cabillic F, Mazières J, Drilon A.
J Clin Oncol. 2017 May 1;35(13):1403-1410. doi: 10.1200/JCO.2016.70.9352. Epub 2017 Mar 13. PMID: 28447912 [PubMed - in process]

AURKA, DLGAP5, TPX2, KIF11 and CKAP5: Five specific mitosis-associated genes correlate with poor prognosis for non-small cell lung cancer patients.
Schneienemann Hider MA, Christopoulos P, Muley T, Warth A, Klingmueller U, Thomas M, Herth FJ, D, Mueller NS, Theis F, Meister M.
Int J Oncol. 2017 Feb;50(2):365-372. doi: 10.3892/ijo.2017.3834. Epub 2017 Jan 2. PMID: 28101582 [PubMed - indexed for MEDLINE] Free PMC Article

Unlocking Data for Statistical Analyses and Data Mining: Generic Case Extraction of Clinical Items from i2b2 and tranSMART.
Firnkorn D, Merker S, Ganzinger M, Muley T, Knaup P.
Stud Health Technol Inform. 2016;228:567-71. PMID: 27577447 [PubMed - indexed for MEDLINE]

[Newborn Screening on Cystic Fibrosis in Germany: Comparison of the new Screening Protocol with an Alternative Protocol].
Sommerburg O, Stahl M, Hammermann J, Okun JG, Kulozik A, Hoffmann G, Mall M.
Klin Padiatr. 2017 Mar;229(2):59-66. doi: 10.1055/s-0042-124187. Epub 2017 Apr 25. German.  PMID: 28444650 [PubMed - in process]
 

Woche 17

Intravenous treprostinil infusion via a fully implantable pump for pulmonary arterial hypertension.
Ewert R, Richter MJ, Steringer-Mascherbauer R, Grünig E, Lange TJ, Opitz CF, Warnke C, Ghofrani HA.
Clin Res Cardiol. 2017 Apr 20. doi: 10.1007/s00392-017-1114-1. [Epub ahead of print] PMID: 28429083 [PubMed - as supplied by publisher

Time to take CT screening to the next level?
Kauczor HU, Heussel CP, von Stackelberg O.
Eur Respir J. 2017 Apr 19;49(4). pii: 1700064. doi: 10.1183/13993003.00064-2017. Print 2017 Apr. No abstract available.  PMID: 28424364 [PubMed - in process]

cR and pR: The Residual Tumor Classification Revisited.
Warth A.
Pathol Oncol Res. 2017 Apr 21. doi: 10.1007/s12253-017-0221-7. [Epub ahead of print] No abstract available. PMID: 28432651 [PubMed - as supplied by publisher]
 

Woche 16

Maternal Phthalate Exposure Promotes Allergic Airway Inflammation over Two Generations Via Epigenetic Modifications.
Jahreis S, Trump S, Bauer M, Bauer T, Thürmann L, Feltens R, Wang Q, Gu L, Grützmann K, Röder S, Averbeck M, Weichenhan D, Plass C, Sack U, Borte M, Dubourg V, Schüürmann G, Simon JC, von Bergen M, Hackermüller J, Eils R, Lehmann I, Polte T.
J Allergy Clin Immunol. 2017 Apr 6. pii: S0091-6749(17)30570-5. doi: 10.1016/j.jaci.2017.03.017. [Epub ahead of print] PMID: 28392331 [PubMed - as supplied by publisher]

Genetic variants of PTPN2 are associated with lung cancer risk: a re-analysis of eight GWASs in the TRICL-ILCCO consortium.
Feng Y, Wang Y, Liu H, Liu Z, Mills C, Han Y, Hung RJ, Brhane Y, McLaughlin J, Brennan P, Bickeboeller H, Rosenberger A, Houlston RS, Caporaso NE, Teresa Landi M, Brueske I, Risch A, Ye Y, Wu X, Christiani DC, Amos CI, Wei Q.
Sci Rep. 2017 Apr 11;7(1):825. doi: 10.1038/s41598-017-00850-0. PMID: 28400551 [PubMed - in process] Free Article

Antacid Therapy and Disease Progression in Patients with Idiopathic Pulmonary Fibrosis Who Received Pirfenidone.
Kreuter M, Spagnolo P, Wuyts W, Renzoni E, Koschel D, Bonella F, Maher TM, Kolb M, Weycker D, Kirchgässler KU, Costabel U.
Respiration. 2017 Apr 12. doi: 10.1159/000468546. [Epub ahead of print] PMID: 28399537 [PubMed - as supplied by publisher]

Erlotinib and bevacizumab in patients with advanced non-small-cell lung cancer and activating EGFR mutations (BELIEF): an international, multicentre, single-arm, phase 2 trial.
Rosell R, Dafni U, Felip E, Curioni-Fontecedro A, Gautschi O, Peters S, Massutí B, Palmero R, Aix SP, Carcereny E, Früh M, Pless M, Popat S, Kotsakis A, Cuffe S, Bidoli P, Favaretto A, Froesch P, Reguart N, Puente J, Coate L, Barlesi F, Rauch D, Thomas M, Camps C, Gómez-Codina J, Majem M, Porta R, Shah R, Hanrahan E, Kammler R, Ruepp B, Rabaglio M, Kassapian M, Karachaliou N, Tam R, Shames DS, Molina-Vila MA, Stahel RA; BELIEF collaborative group..
Lancet Respir Med. 2017 Apr 10. pii: S2213-2600(17)30129-7. doi: 10.1016/S2213-2600(17)30129-7. [Epub ahead of print] PMID: 28408243 [PubMed - as supplied by publisher]

The Future of Radioligand Therapy: Alpha, beta or both?
Haberkorn UA, Giesel F, Morgenstern A, Kratochwil C.
J Nucl Med. 2017 Apr 13. pii: jnumed.117.190124. doi: 10.2967/jnumed.117.190124. [Epub ahead of print] No abstract available.  PMID: 28408527 [PubMed - as supplied by publisher]
 

Woche 15

Cellular prion protein PRPC and ecto-5'-nucleotidase are markers of the cellular stress response to aneuploidy.
Domingues PH, Nanduri LS, Seget K, Venkateswaran SV, Agorku D, Viganó C, von Schubert C, Nigg EA, Swanton C, Sotillo R, Bosio A, Storchová Z, Hardt O.
Cancer Res. 2017 Apr 4. pii: canres.3052.2016. doi: 10.1158/0008-5472.CAN-16-3052. [Epub ahead of print] PMID: 28377454 [PubMed - as supplied by publisher]

Necitumumab plus Gemcitabine and Cisplatin as First-Line Therapy in Patients with Stage IV EGFR- Expressing Squamous Non-Small-Cell Lung Cancer: German Subgroup Data from an Open-Label, Randomized Controlled Phase 3 Study (SQUIRE).
Reck M, Thomas M, Kropf-Sanchen C, Mezger J, Socinski MA, Depenbrock H, Soldatenkova V, Brown J, Krause T, Thatcher N.
Oncol Res Treat. 2016;39(9):539-47. doi: 10.1159/000448085. Epub 2016 Aug 2. PMID: 27614872 [PubMed - indexed for MEDLINE] Free Article

[Exon-dependent Subgroup-analysis of the Non-interventional REASON-Study: PFS and OS in EGFR-mutated NSCLC Patients Treated with Gefitinib or Chemotherapy].
Schuette W, Dietel M, Thomas M, Eberhardt W, Griesinger F, Zirrgiebel U, Radke S, Schirmacher P.
Pneumologie. 2016 Aug;70(8):514-21. doi: 10.1055/s-0042-109749. Epub 2016 Aug 11. German.  PMID: 27512931 [PubMed - indexed for MEDLINE]

[Subgroup Analysis of the Non-interventional REASON Study: PFS and OS According to Age, Smoking History, Gender, and Histology in NSCLC Patients Treated with Gefitinib or Chemotherapy].
Schuette W, Eberhardt WE, Waller C, Schirmacher P, Dietel M, Zirrgiebel U, Radke S, Thomas M.
Pneumologie. 2016 Sep;70(9):579-88. doi: 10.1055/s-0042-109760. Epub 2016 Sep 7. German.  PMID: 27603946 [PubMed - indexed for MEDLINE]

Experimental design and data analysis of Ago-RIP-Seq experiments for the identification of microRNA targets.
Tichy D, Anna Pickl JM, Benner A, Sültmann H. Brief Bioinform. 2017 Mar 31. doi: 10.1093/bib/bbx032. [Epub ahead of print] PMID: 28379479 [PubMed - as supplied by publisher]

Functional variants in DCAF4 associated with lung cancer risk in European populations.
Liu H, Liu Z, Wang Y, Stinchcombe TE, Owzar K, Han Y, Hung RJ, Brhane Y, McLaughlin J, Brennan P, Bickeböller H, Rosenberger A, Houlston RS, Caporaso N, Landi MT, Brüske I, Risch A, Wu X, Ye Y, Christiani DC; Transdisciplinary Research in Cancer of the Lung (TRICL) Research Team., Amos CI, Wei Q.
Carcinogenesis. 2017 Apr 5. doi: 10.1093/carcin/bgx033. [Epub ahead of print] PMID: 28383684 [PubMed - as supplied by publisher]

[German Validation of the "King's Brief Interstitial Lung Disease (K-Bild) Health Status Questionnaire"].
Kreuter M, Birring SS, Wijsenbeek M, Wapenaar M, Oltmanns U, Costabel U, Bonella F.
Pneumologie. 2016 Nov;70(11):742-746. Epub 2016 Sep 21. German.  PMID: 27652583 [PubMed - indexed for MEDLINE]
 

Woche 14

Late outcomes after acute pulmonary embolism: rationale and design of FOCUS, a prospective observational multicenter cohort study.
Konstantinides SV, Barco S, Rosenkranz S, Lankeit M, Held M, Gerhardt F, Bruch L, Ewert R, Faehling M, Freise J, Ghofrani HA, Grünig E, Halank M, Heydenreich N, Hoeper MM, Leuchte HH, Mayer E, Meyer FJ, Neurohr C, Opitz C, Pinto A, Seyfarth HJ, Wachter R, Zäpf B, Wilkens H, Binder H, Wild PS.
J Thromb Thrombolysis. 2016 Nov;42(4):600-9. doi: 10.1007/s11239-016-1415-7. PMID: 27577542 [PubMed - indexed for MEDLINE] Free PMC Article

[ESC guidelines 2015 pulmonary hypertension: diagnosis and treatment].
Opitz C, Rosenkranz S, Ghofrani HA, Grünig E, Klose H, Olschewski H, Hoeper M.
Dtsch Med Wochenschr. 2016 Nov;141(24):1764-1769. Epub 2016 Nov 30. German.  PMID: 27903027 [PubMed - indexed for MEDLINE]

[Pulmonary Hypertension: Cologne Consensus Conference 2016].
Rosenkranz S, Ghofrani HA, Grünig E, Klose H, Olschewski H, Opitz C, Hoeper M.
Dtsch Med Wochenschr. 2016 Nov;141(24):1778-1782. Epub 2016 Nov 8. Review. German. PMID: 27825176 [PubMed - indexed for MEDLINE]

Imaging of Cystic Fibrosis Lung Disease and Clinical Interpretation.
Wielpütz MO, Eichinger M, Biederer J, Wege S, Stahl M, Sommerburg O, Mall MA, Kauczor HU, Puderbach M.
Rofo. 2016 Sep;188(9):834-45. doi: 10.1055/s-0042-104936. Epub 2016 Apr 13. Review. PMID: 27074425 [PubMed - indexed for MEDLINE] Free Article

The double-edged sword of (re)expression of genes by hypomethylating agents: from viral mimicry to exploitation as priming agents for targeted immune checkpoint modulation.
Wolff F, Leisch M, Greil R, Risch A, Pleyer L.
Cell Commun Signal. 2017 Mar 31;15(1):13. doi: 10.1186/s12964-017-0168-z. Review. PMID: 28359286 [PubMed - in process]
 

Woche 13

Endobronchial Ultrasound Elastography for Evaluation of Intrathoracic Lymph Nodes: A Pilot Study.
Sun J, Zheng X, Mao X, Wang L, Xiong H, Herth FJ, Han B.
Respiration. 2017 Mar 22. doi: 10.1159/000464253. [Epub ahead of print] PMID: 28324873 [PubMed - as supplied by publisher]

[WeanNet: The network of weaning units of the DGP (Deutsche Gesellschaft für Pneumologie und Beatmungsmedizin) - results to epidemiology an outcome in patients with prolonged weaning].WeanNet Study Group.
Dtsch Med Wochenschr. 2016 Sep;141(18):e166-72. doi: 10.1055/s-0042-112345. Epub 2016 Sep 6. German.  PMID: 27598922 [PubMed - indexed for MEDLINE]

Pulmonary ground-glass opacity: computed tomography features, histopathology and molecular pathology.
Gao JW, Rizzo S, Ma LH, Qiu XY, Warth A, Seki N, Hasegawa M, Zou JW, Li Q, Femia M, Lv TF, Song Y; written on behalf of the AME Lung Cancer Collaborative Group..
Transl Lung Cancer Res. 2017 Feb;6(1):68-75. doi: 10.21037/tlcr.2017.01.02. Review. PMID: 28331826 [PubMed - in process] Free Article

Pan-cancer analysis distinguishes transcriptional changes of aneuploidy from proliferation.
Buccitelli C, Salgueiro L, Rowald K, Sotillo R, Mardin BR, Korbel JO.
Genome Res. 2017 Mar 20. doi: 10.1101/gr.212225.116. [Epub ahead of print] PMID: 28320919 [PubMed - as supplied by publisher]

Targeted Ablation Using Laser Nanosurgery.
Gayathri Vegesna NV, Ronchi P, Durdu S, Terjung S, Pepperkok R.
Methods Mol Biol. 2017;1563:107-125. doi: 10.1007/978-1-4939-6810-7_8. PMID: 28324605 [PubMed - in process]
 

Woche 12

Dephasing and diffusion on the alveolar surface.
Buschle LR, Kurz FT, Kampf T, Wagner WL, Duerr J, Stiller W, Konietzke P, Wünnemann F, Mall MA, Wielpütz MO, Schlemmer HP, Ziener CH.
Phys Rev E. 2017 Feb;95(2-1):022415. doi: 10.1103/PhysRevE.95.022415. PMID: 28297921 [PubMed - in process]

Associations between genetic variants in mRNA splicing-related genes and risk of lung cancer: a pathway-based analysis from published GWASs.
Pan Y, Liu H, Wang Y, Kang X, Liu Z, Owzar K, Han Y, Su L, Wei Y, Hung RJ, Brhane Y, McLaughlin J, Brennan P, Bickeböller H, Rosenberger A, Houlston RS, Caporaso N, Teresa Landi M, Heinrich J, Risch A, Wu X, Ye Y, Christiani DC, Amos CI, Wei Q. Sci Rep. 2017 Mar 17;7:44634. doi: 10.1038/srep44634. PMID: 28304396 [PubMed - in process]

A randomized, open-label, multicenter, phase II study evaluating the efficacy and safety of BTH1677 (1,3-1,6 beta glucan; Imprime PGG) in combination with cetuximab and chemotherapy in patients with advanced non-small cell lung cancer.
Thomas M, Sadjadian P, Kollmeier J, Lowe J, Mattson P, Trout JR, Gargano M, Patchen ML, Walsh R, Beliveau M, Marier JF, Bose N, Gorden K, Schneller F 3rd.
Invest New Drugs. 2017 Mar 16. doi: 10.1007/s10637-017-0450-3. [Epub ahead of print] PMID: 28303530 [PubMed - as supplied by publisher]

Multicyclic Peptides as Scaffolds for the Development of Tumor Targeting Agents.
Loktev A, Haberkorn U, Mier W.
Curr Med Chem. 2017 Mar 16. doi: 10.2174/0929867324666170316120304. [Epub ahead of print] PMID: 28302013 [PubMed - as supplied by publisher]
 

Woche 11

Blood Eosinophils and Response to Maintenance COPD Treatment: Data from the FLAME Trial.
Roche N, Chapman KR, Vogelmeier CF, Herth FJ, Thach C, Fogel R, Olsson P, Patalano F, Banerji D, Wedzicha JA.
Am J Respir Crit Care Med. 2017 Mar 9. doi: 10.1164/rccm.201701-0193OC. [Epub ahead of print] PMID: 28278391 [PubMed - as supplied by publisher]

SMARCA4 and SMARCA2 deficiency in non-small cell lung cancer: immunohistochemical survey of 316 consecutive specimens.
Herpel E, Rieker RJ, Dienemann H, Muley T, Meister M, Hartmann A, Warth A, Agaimy A.
Ann Diagn Pathol. 2017 Feb;26:47-51. doi: 10.1016/j.anndiagpath.2016.10.006. PMID: 28038711 [PubMed - indexed for MEDLINE]

Gene-set meta-analysis of lung cancer identifies pathway related to systemic lupus erythematosus.
Rosenberger A, Sohns M, Friedrichs S, Hung RJ, Fehringer G, McLaughlin J, Amos CI, Brennan P, Risch A, Brüske I, Caporaso NE, Landi MT, Christiani DC, Wei Y, Bickeböller H.
PLoS One. 2017 Mar 8;12(3):e0173339. doi: 10.1371/journal.pone.0173339. PMID: 28273134 [PubMed - in process] Free Article

Screening for lung cancer: Does MRI have a role?
Biederer J, Ohno Y, Hatabu H, Schiebler ML, van Beek EJ, Vogel-Claussen J, Kauczor HU.
Eur J Radiol. 2017 Jan;86:353-360. doi: 10.1016/j.ejrad.2016.09.016. Review. PMID: 27665148 [PubMed - indexed for MEDLINE]

Management of COPD: Is there a role for quantitative imaging?
Kirby M, van Beek EJ, Seo JB, Biederer J, Nakano Y, Coxson HO, Parraga G.
Eur J Radiol. 2017 Jan;86:335-342. doi: 10.1016/j.ejrad.2016.08.022. Review. PMID: 27592252 [PubMed - indexed for MEDLINE]
 

Woche 10

Gene signature driving invasive mucinous adenocarcinoma of the lung.
Guo M, Tomoshige K, Meister M, Muley T, Fukazawa T, Tsuchiya T, Karns R, Warth A, Fink-Baldauf IM, Nagayasu T, Naomoto Y, Xu Y, Mall MA, Maeda Y.
EMBO Mol Med. 2017 Mar 2. pii: e201606711. doi: 10.15252/emmm.201606711. [Epub ahead of print] PMID: 28255028 [PubMed - as supplied by publisher] Free Article

Pulmonary Hypertension.
Hoeper MM, Ghofrani HA, Grünig E, Klose H, Olschewski H, Rosenkranz S.
Dtsch Arztebl Int. 2017 Feb 3;114(5):73-84. doi: 10.3238/arztebl.2017.0073.PMID: 28241922 [PubMed - in process] Free Article

Reflection of illness and strategies for handling advanced lung cancer - a qualitative analysis in patients and their relatives.
Sparla A, Flach-Vorgang S, Villalobos M, Krug K, Kamradt M, Coulibaly K, Szecsenyi J, Thomas M, Gusset-Bährer S, Ose D.
BMC Health Serv Res. 2017 Mar 2;17(1):173. doi: 10.1186/s12913-017-2110-x. PMID: 28253884 [PubMed - in process
 

Woche 09

Interventional pulmonology in chronic obstructive pulmonary disease.
Gompelmann D, Sarmand N, Herth FJ. Curr Opin Pulm Med. 2017 Feb 17.
doi: 10.1097/MCP.0000000000000373. [Epub ahead of print] PMID: 28221172 [PubMed - as supplied by publisher]

The yin and yang of idiopathic pulmonary fibrosis.
Kreuter M, Cottin V. Eur Respir J. 2017 Feb 23;49(2). pii: 1602316. doi: 10.1183/13993003.02316-2016. No abstract available.
PMID: 28232416 [PubMed - in process]

What patients with pulmonary fibrosis and their partners think: a live, educative survey in the Netherlands and Germany.
van Manen MJ, Kreuter M, van den Blink B, Oltmanns U, Palmowski K, Brunnemer E, Hummler S, Tak NC, van den Toorn L, Miedema J, Hoogsteden HC, Wijsenbeek MS.
ERJ Open Res. 2017 Feb 14;3(1). pii: 00065-2016. doi: 10.1183/23120541.00065-2016. PMID: 28229083 [PubMed - in process] Free PMC Article
 

Woche 08

Reproducibility and comparison of oxygen-enhanced T1 quantification in COPD and asthma patients.
Triphan SM, Jobst BJ, Anjorin A, Sedlaczek O, Wolf U, Terekhov M, Hoffmann C, Ley S, Düber C, Biederer J, Kauczor HU, Jakob PM, Wielpütz MO.
PLoS One. 2017 Feb 16;12(2):e0172479. doi: 10.1371/journal.pone.0172479. PMID: 28207845 [PubMed - in process] Free Article

Comparison of hemodynamic parameters in treatment-naïve and pre-treated patients with pulmonary arterial hypertension in the randomized phase III PATENT-1 study.
Galiè N, Grimminger F, Grünig E, Hoeper MM, Humbert M, Jing ZC, Keogh AM, Langleben D, Rubin LJ, Fritsch A, Davie N, Ghofrani HA.
J Heart Lung Transplant. 2016 Dec 24. pii: S1053-2498(16)30472-7. doi: 10.1016/j.healun.2016.12.012. [Epub ahead of print] PMID: 28190787 [PubMed - as supplied by publisher] Free Article

Crosstalk between glucocorticoids and IL-4 modulates Ym1 expression in alternatively activated myeloid cells.
Ng Kuet Leong N, Brombacher F, Dalpke AH, Weitnauer M.
Immunobiology. 2017 Feb 9. pii: S0171-2985(17)30019-0. doi: 10.1016/j.imbio.2017.02.003. [Epub ahead of print] PMID: 28209270 [PubMed - as supplied by publisher]

Endobronchial ultrasound: launch of an ERS structured training programme.
Farr A, Clementsen P, Herth F, Konge L, Rohde G, Dowsland S, Schuhmann M, Annema J.
Breathe (Sheff). 2016 Sep;12(3):217-220. doi: 10.1183/20734735.013116. PMID: 28210294 [PubMed] Free PMC Article

Interstitial lung diseases: course report.
Kreuter M, Zeynel S, Mishra DR.
Breathe (Sheff). 2016 Sep;12(3):213-215. doi: 10.1183/20734735.011516.PMID: 28210293 [PubMed] Free PMC Article
 

Woche 07

Coil therapy for patients with severe emphysema and bilateral incomplete fissures - effectiveness and complications after 1-year follow-up: a single-center experience.
Kontogianni K, Gerovasili V, Gompelmann D, Schuhmann M, Hoffmann H, Heussel CP, Herth FJ, Eberhardt R. Int J Chron Obstruct Pulmon Dis. 2017 Jan 23;12:383-394. doi: 10.2147/COPD.S117655. PMID: 28176954 [PubMed - in process] Free PMC Article

Protean proteases: at the cutting edge of lung diseases.
Taggart C, Mall MA, Lalmanach G, Cataldo D, Ludwig A, Janciauskiene S, Heath N, Meiners S, Overall CM, Schultz C, Turk B, Borensztajn KS.
Eur Respir J. 2017 Feb 8;49(2). pii: 1501200. doi: 10.1183/13993003.01200-2015. PMID: 28179435 [PubMed - in process]
 

Woche 06

Pathway-analysis of published genome-wide association studies of lung cancer: A potential role for the CYP4F3 locus.
Yin J, Liu H, Liu Z, Owzar K, Han Y, Su L, Wei Y, Hung RJ, Brhane Y, McLaughlin J, Brennan P, Bickeboeller H, Rosenberger A, Houlston RS, Caporaso N, Landi MT, Heinrich J, Risch A, Christiani DC, Amos CI, Wei Q. Mol Carcinog. 2017 Feb 2. doi: 10.1002/mc.22622. [Epub ahead of print] PMID: 28150878 [PubMed - as supplied by publisher]

Regional Lung Ventilation Analysis Using Temporally Resolved Magnetic Resonance Imaging.
Kolb C, Wetscherek A, Buzan MT, Werner R, Rank CM, Kachelrie M, Kreuter M, Dinkel J, Heussel CP, Maier-Hein K. J Comput Assist Tomogr. 2016 Nov/Dec;40(6):899-906. PMID: 27331925 [PubMed - indexed for MEDLINE]

[The new TNM classification for lung tumors : Changes and the assessment of multiple tumor foci].
Harms A, Kriegsmann M, Fink L, Länger F, Warth A.
Pathologe. 2017 Feb 2. doi: 10.1007/s00292-017-0268-y. [Epub ahead of print] German.  PMID: 28154917 [PubMed - as supplied by publisher]
 

Woche 05

Protein abundance of AKT and ERK pathway components governs cell type-specific regulation of proliferation.
Adlung L, Kar S, Wagner MC, She B, Chakraborty S, Bao J, Lattermann S, Boerries M, Busch H, Wuchter P, Ho AD, Timmer J, Schilling M, Höfer T, Klingmüller U.
Mol Syst Biol. 2017 Jan 24;13(1):904. doi: 10.15252/msb.20167258. PMID: 28123004 [PubMed - in process] Free Article

Genetic Variants in Epigenetic Pathways and Risks of Multiple Cancers in the GAME-ON Consortium.
Toth R, Scherer D, Kelemen LE, Risch A, Hazra A, Balavarca Y, Issa JJ, Moreno V, Eeles RA, Ogino S, Wu X, Ye Y, Hung RJ, Goode EL, Ulrich CM.
Cancer Epidemiol Biomarkers Prev. 2017 Jan 23. pii: cebp.0728.2016. doi: 10.1158/1055-9965.EPI-16-0728. [Epub ahead of print] PMID: 28115406 [PubMed - as supplied by publisher]

Diagnosis of Cystic Fibrosis in Screened Populations.
Farrell PM, White TB, Howenstine MS, Munck A, Parad RB, Rosenfeld M, Sommerburg O, Accurso FJ, Davies JC, Rock MJ, Sanders DB, Wilschanski M, Sermet-Gaudelus I, Blau H, Gartner S, McColley SA.
J Pediatr. 2017 Feb;181S:S33-S44.e2. doi: 10.1016/j.jpeds.2016.09.065. PMID: 28129810 [PubMed - in process]

Breaking New Ground: The Evolving Concept of Spread through Air Spaces (STAS).
Warth A, Beasley MB, Mino-Kenudson M.
J Thorac Oncol. 2017 Feb;12(2):176-178. doi: 10.1016/j.jtho.2016.10.020. Editiorial - No abstract available.
 

Woche 04

Acquisition and adaptation of the airway microbiota in the early life of cystic fibrosis patients.
Boutin S, Dalpke AH.
Mol Cell Pediatr. 2017 Dec;4(1):1. doi: 10.1186/s40348-016-0067-1. Review. PMID: 28097632 [PubMed - in process]

Airway mucus, inflammation and remodeling: emerging links in the pathogenesis of chronic lung diseases.
Zhou-Suckow Z, Duerr J, Hagner M, Agrawal R, Mall MA.
Cell Tissue Res. 2017 Jan 20. doi: 10.1007/s00441-016-2562-z. [Epub ahead of print] Review. PMID: 28108847 [PubMed - as supplied by publisher]
 

AURKA, DLGAP5, TPX2, KIF11 and CKAP5: Five specific mitosis-associated genes correlate with poor prognosis for non-small cell lung cancer patients.
Schneider MA, Christopoulos P, Muley T, Warth A, Klingmueller U, Thomas M, Herth FJ, Dienemann H, Mueller NS, Theis F, Meister M.
Int J Oncol. 2017 Feb;50(2):365-372. doi: 10.3892/ijo.2017.3834. PMID: 28101582 [PubMed - in process]

Prognostic Impact of CT-Quantified Muscle and Fat Distribution before and after First-Line-Chemotherapy in Lung Cancer Patients.
Nattenmüller J, Wochner R, Muley T, Steins M, Hummler S, Teucher B, Wiskemann J, Kauczor HU, Wielpütz MO, Heussel CP.
PLoS One. 2017 Jan 20;12(1):e0169136. doi: 10.1371/journal.pone.0169136. PMID: 28107410 [PubMed - in process] Free Article

Cross-Sectional Survey on Bronchoscopy in Germany--The Current Status of Clinical Practice.
Hautmann H, Hetzel J, Eberhardt R, Stanzel F, Wagner M, Schneider A, Dirschinger R, Poszler A.
Pneumologie. 2016 Feb;70(2):110-6. doi: 10.1055/s-0041-110288. PMID: 26894392 [PubMed - indexed for MEDLINE]
 

 
Woche 03

Serial assessment of pulmonary lesion volume by computed tomography allows survival prediction in invasive pulmonary aspergillosis.
Vehreschild JJ, Heussel CP, Groll AH, Vehreschild MJ, Silling G, Würthwein G, Brecht M, Cornely OA.
Eur Radiol. 2017 Jan 12. doi: 10.1007/s00330-016-4717-4. [Epub ahead of print] PMID: 28083695 [PubMed - as supplied by publisher]

TTCA: an R package for the identification of differentially expressed genes in time course microarray data.
Albrecht M, Stichel D, Müller B, Merkle R, Sticht C, Gretz N, Klingmüller U, Breuhahn K, Matthäus F.
BMC Bioinformatics. 2017 Jan 14;18(1):33. doi: 10.1186/s12859-016-1440-8. PMID: 28088176 [PubMed - in process]
 

Woche 02

SMARCA4 and SMARCA2 deficiency in non-small cell lung cancer: immunohistochemical survey of 316 consecutive specimens.
Herpel E, Rieker RJ, Dienemann H, Muley T, Meister M, Hartmann A, Warth A, Agaimy A.
Ann Diagn Pathol. 2017 Feb;26:47-51. doi: 10.1016/j.anndiagpath.2016.10.006. PMID: 28038711 [PubMed - in process]

[Local treatment of solitary intrapulmonary, malignant nodules].
Op den Winkel J, Eichhorn F, Rieken S, Dienemann H. Radiologe. 2017 Jan 4. doi: 10.1007/s00117-016-0200-0. [Epub ahead of print] German.
PMID: 28054137 [PubMed - as supplied by publisher]

Cardiopulmonary exercise testing for detecting pulmonary arterial hypertension in systemic sclerosis.
Dumitrescu D, Nagel C, Kovacs G, Bollmann T, Halank M, Winkler J, Hellmich M, Grünig E, Olschewski H, Ewert R, Rosenkranz S.
Heart. 2017 Jan 6. pii: heartjnl-2016-309981. doi: 10.1136/heartjnl-2016-309981. [Epub ahead of print] PMID: 28062514 [PubMed - as supplied by publisher]

The expansion and performance of national newborn screening programmes for cystic fibrosis in Europe.
Barben J, Castellani C, Dankert-Roelse J, Gartner S, Kashirskaya N, Linnane B, Mayell S, Munck A, Sands D, Sommerburg O, Pybus S, Winters V, Southern KW.
J Cyst Fibros. 2016 Dec 30. pii: S1569-1993(16)30681-6. doi: 10.1016/j.jcf.2016.12.012. [Epub ahead of print] PMID: 28043799 [PubMed - as supplied by publisher]

Hypoxia and sterile inflammation in cystic fibrosis airways: mechanisms and potential therapies.
Montgomery ST, Mall MA, Kicic A, Stick SM; AREST CF. Eur Respir J. 2017 Jan 4;49(1). pii: 1600903. doi: 10.1183/13993003.00903-2016. Review. PMID: 28052955 [PubMed - in process]
 

Woche 01

ALK-Testing in non-small cell lung cancer (NSCLC): Immunohistochemistry (IHC) and/or fluorescence in-situ Hybridisation (FISH)?: Statement of the Germany Society for Pathology (DGP) and the Working Group Thoracic Oncology (AIO) of the German Cancer Society e.V. (Stellungnahme der Deutschen Gesellschaft für Pathologie und der AG Thorakale Onkologie der Arbeitsgemeinschaft Onkologie/Deutsche Krebsgesellschaft e.V.).
von Laffert M, Schirmacher P, Warth A, Weichert W, Büttner R, Huber RM, Wolf J, Griesinger F, Dietel M, Grohé C. Lung Cancer. 2017 Jan; 103:1-5. doi: 10.1016 / j.lungcan. 2016.11.008. PMID: 28024689 [Unknown status]