Publikationen

Diese Woche Neu TLRC Fakultät 2021

Woche 52 (27.12.-02.01.)

[Increased pulmonary arterial and venous pressure]. Melzig C, Rengier F. Radiologe. 2021 Dec 30. doi: 10.1007/s00117-021-00951-y. Online ahead of print. PMID: 34967911 Review. German.

Woche 51 (20.12.-26.12.)

Acquisition of a Dose Management System with Consideration of Medico-Legal and Economic Aspects. Do TD, Melzig C, Kauczor HU, Weber MA, Wielpütz MO. Rofo. 2021 Dec 21. doi: 10.1055/a-1710-3529. Online ahead of print. PMID: 34933353 English, German.

Effects of Elexacaftor/Tezacaftor/Ivacaftor Therapy on CFTR Function in Patients with Cystic Fibrosis and One or Two F508del Alleles. Graeber SY, Vitzthum C, Pallenberg ST, Naehrlich L, Stahl M, Rohrbach A, Drescher M, Minso R, Ringshausen FC, Rueckes-Nilges C, Klajda J, Berges J, Yu Y, Scheuermann H, Hirtz S, Sommerburg O, Dittrich AM, Tümmler B, Mall MA. Am J Respir Crit Care Med. 2021 Dec 22. doi: 10.1164/rccm.202110-2249OC. Online ahead of print. PMID: 34936849

Pirfenidone in Unclassifiable Interstitial Lung Disease: A Subgroup Analysis by Concomitant Mycophenolate Mofetil and/or Previous Corticosteroid Use. Kreuter M, Maher TM, Corte TJ, Molina-Molina M, Axmann J, Gilberg F, Kirchgaessler KU, Cottin V. Adv Ther. 2021 Dec 22. doi: 10.1007/s12325-021-02009-w. Online ahead of print. PMID: 34936057

Ageing-related markers and risks of cancer and cardiovascular disease: a prospective study in the EPIC-Heidelberg cohort. Srour B, Kaaks R, Johnson T, Hynes LC, Kühn T, Katzke VA. Eur J Epidemiol. 2021 Dec 22. doi: 10.1007/s10654-021-00828-3. Online ahead of print. PMID: 34935094

Woche 50 (13.12.-19.12.)

In Search of a Sensor: How Does CO2 Regulate Alveolar Ion Transport? Baloğlu E, Mairbäurl H. Am J Respir Cell Mol Biol. 2021 Dec;65(6):571-572. doi: 10.1165/rcmb.2021-0270ED. PMID: 34348088 Free PMC article. No abstract available.

MARIPOSA: phase 3 study of first-line amivantamab + lazertinib versus osimertinib in EGFR-mutant non-small cell lung cancer. Cho BC, Felip E, Hayashi H, Thomas M, Lu S, Besse B, Sun T, Martinez M, Sethi SN, Shreeve SM, Spira AI. Future Oncol. 2021 Dec 16. doi: 10.2217/fon-2021-0923. Online ahead of print. PMID: 34911336

Effect of Minimally Invasive Surfactant Therapy vs Sham Treatment on Death or Bronchopulmonary Dysplasia in Preterm Infants With Respiratory Distress Syndrome: The OPTIMIST-A Randomized Clinical Trial. Dargaville PA, Kamlin COF, Orsini F, Wang X, De Paoli AG, Kanmaz Kutman HG, Cetinkaya M, Kornhauser-Cerar L, Derrick M, Özkan H, Hulzebos CV, Schmölzer GM, Aiyappan A, Lemyre B, Kuo S, Rajadurai VS, O'Shea J, Biniwale M, Ramanathan R, Kushnir A, Bader D, Thomas MR, Chakraborty M, Buksh MJ, Bhatia R, Sullivan CL, Shinwell ES, Dyson A, Barker DP, Kugelman A, Donovan TJ, Tauscher MK, Murthy V, Ali SKM, Yossuck P, Clark HW, Soll RF, Carlin JB, Davis PG; OPTIMIST-A Trial Investigators. JAMA. 2021 Dec 13. doi: 10.1001/jama.2021.21892. Online ahead of print. PMID: 34902013

Donor NK and T Cells in the Periphery of Lung Transplant Recipients Contain High Frequencies of Killer Cell Immunoglobulin-Like Receptor-Positive Subsets. Hitz AM, Bläsing KA, Wiegmann B, Bellmàs-Sanz R, Chichelnitskiy E, Wandrer F, Horn LM, Neudörfl C, Keil J, Beushausen K, Ius F, Sommer W, Avsar M, Kühn C, Tudorache I, Salman J, Siemeni T, Haverich A, Warnecke G, Falk CS, Kühne JF. Front Immunol. 2021 Dec 13;12:778885. doi: 10.3389/fimmu.2021.778885. eCollection 2021. PMID: 34966390 Free PMC article.

p53 partial loss-of-function mutations sensitize to chemotherapy. Klimovich B, Merle N, Neumann M, Elmshäuser S, Nist A, Mernberger M, Kazdal D, Stenzinger A, Timofeev O, Stiewe T. Oncogene. 2021 Dec 14. doi: 10.1038/s41388-021-02141-5. Online ahead of print. PMID: 34907344

Bronchial Thermoplasty Global Registry (BTGR): 2-year results. Torrego A, Herth FJ, Munoz-Fernandez AM, Puente L, Facciolongo N, Bicknell S, Novali M, Gasparini S, Bonifazi M, Dheda K, Andreo F, Votruba P, Langton D, Flandes J, Fielding D, Bonta PI, Skowasch D, Schulz C, Darwiche K, McMullen E, Grubb GM, Niven R. BMJ Open. 2021 Dec 16;11(12):e053854. doi: 10.1136/bmjopen-2021-053854. PMID: 34916324

Woche 49 (06.12.-12.12.)

Early identification of disease progression in ALK-rearranged lung cancer using circulating tumor DNA analysis. Angeles AK, Christopoulos P, Yuan Z, Bauer S, Janke F, Ogrodnik SJ, Reck M, Schlesner M, Meister M, Schneider MA, Dietz S, Stenzinger A, Thomas M, Sültmann H. NPJ Precis Oncol. 2021 Dec 7;5(1):100. doi: 10.1038/s41698-021-00239-3. PMID: 34876698

Impact of molecular alterations on quality of life and prognostic understanding over time in patients with incurable lung cancer: a multicenter, longitudinal, prospective cohort study. Kuon J, Blasi M, Unsöld L, Vogt J, Mehnert A, Alt-Epping B, van Oorschot B, Sistermanns J, Ahlborn M, Ritterbusch U, Stevens S, Kahl C, Ruellan A, Matthias K, Kubin T, Stahlhut K, Heider A, Lordick F, Thomas M; Arbeitsgemeinschaft Palliativmedizin (APM) of the German Cancer Society (DKG). Support Care Cancer. 2021 Dec 7. doi: 10.1007/s00520-021-06736-2. Online ahead of print. PMID: 34877613

Prognostic phenotypes of early-stage lung adenocarcinoma. Lamort AS, Kaiser JC, Pepe MAA, Lilis I, Ntaliarda G, Somogyi K, Spella M, Behrend SJ, Giotopoulou GA, Kujawa W, Lindner M, Koch I, Hatz RA, Behr J, Sotillo R, Schamberger AC, Stathopoulos GT. Eur Respir J. 2021 Dec 9:2101674. doi: 10.1183/13993003.01674-2021. Online ahead of print. PMID: 34887322

Case Series: Convalescent Plasma Therapy for Patients with COVID-19 and Primary Antibody Deficiency.v Lang-Meli J, Fuchs J, Mathé P, Ho HE, Kern L, Jaki L, Rusignuolo G, Mertins S, Somogyi V, Neumann-Haefelin C, Trinkmann F, Müller M, Thimme R, Umhau M, Quinti I, Wagner D, Panning M, Cunningham-Rundles C, Laubner K, Warnatz K. J Clin Immunol. 2021 Dec 10. doi: 10.1007/s10875-021-01193-2. Online ahead of print. PMID: 34893946

The Impact of the Envisia Genomic Classifier in the Diagnosis and Management of Patients with Idiopathic Pulmonary Fibrosis. Lasky JA, Case A, Unterman A, Kreuter M, Scholand MB, Chaudhary S, Lofaro LR, Johnson M, Huang J, Bhorade SM, Kennedy GC. Ann Am Thorac Soc. 2021 Dec 10. doi: 10.1513/AnnalsATS.202107-897OC. Online ahead of print. PMID: 34889723

A Volatile and Dynamic Longitudinal Microbiome Is Associated With Less Reduction in Lung Function in Adolescents With Cystic Fibrosis. Metzger MI, Graeber SY, Stahl M, Sommerburg O, Mall MA, Dalpke AH, Boutin S. Front Cell Infect Microbiol. 2021 Dec 6;11:763121. doi: 10.3389/fcimb.2021.763121. eCollection 2021. PMID: 34938669 Free PMC article.

Woche 48 (29.11.-05.12.)

Mad2 Induced Aneuploidy Contributes to Eml4-Alk Driven Lung Cancer by Generating an Immunosuppressive Environment. Alikhanyan K, Chen Y, Somogyi K, Kraut S, Sotillo R. Cancers (Basel). 2021 Nov 30;13(23):6027. doi: 10.3390/cancers13236027. PMID: 34885137

Diagnostic Yield of Transbronchial Lung Cryobiopsy Compared to Transbronchial Forceps Biopsy in Patients with Sarcoidosis in a Prospective, Randomized, Multicentre Cross-Over Trial. Häntschel M, Eberhardt R, Petermann C, Gesierich W, Darwiche K, Hagmeyer L, Colby TV, Fend F, Theegarten D, Wintzer HO, Kreuter M, Spengler W, Behrens-Zemek AF, Lewis RA, Evrard HC, Ehab A, Böckeler M, Hetzel J. J Clin Med. 2021 Dec 2;10(23):5686. doi: 10.3390/jcm10235686. PMID: 34884387

Risk Factors, Treatment and Prognosis of Patients with Lung Cancer after Heart Transplantation. Heil KM, Helmschrott M, Darche FF, Bruckner T, Ehlermann P, Kreusser MM, Doesch AO, Sommer W, Warnecke G, Frey N, Rivinius R. Life (Basel). 2021 Dec 4;11(12):1344. doi: 10.3390/life11121344. PMID: 34947875

MRI of Pulmonary Nodules: Closing the Gap on CT. Wielpütz MO. Radiology. 2021 Nov 30:212516. doi: 10.1148/radiol.212516. Online ahead of print. PMID: 34846207 No abstract available.

Outcomes and Incidence of PF-ILD According to Different Definitions in a Real-World Setting. Torrisi SE, Kahn N, Wälscher J, Polke M, Lee JS, Molyneaux PL, Sambataro FM, Heussel CP, Vancheri C, Kreuter M. Front Pharmacol. 2021 Dec 17;12:790204. doi: 10.3389/fphar.2021.790204. eCollection 2021. PMID: 34975486 Free PMC article.

Woche 47 (22.11.-28.11.)

Pathologic responses in oligometastatic NSCLC patients treated with neoadjuvant immune checkpoint blockade with and without chemotherapy followed by surgery. Boch T, Frost N, Sommer L, Overbeck TR, Michaeli CT, Szuszies CJ, Rieckmann LM, Beumer N, Imbusch CD, Winter H, Thomas M, Roeper J, Janning M, Griesinger F, Wermke M, Loges S. Lung Cancer. 2021 Nov 23;164:46-51. doi: 10.1016/j.lungcan.2021.11.009. Online ahead of print. PMID: 34998106

Lower Prevalence of Osteoporosis in Patients with COPD Taking Anti-Inflammatory Compounds for the Treatment of Diabetes: Results from COSYCONET. Kahnert K, Jörres RA, Lucke T, Trudzinski FC, Mertsch P, Bickert C, Ficker JH, Behr J, Bals R, Watz H, Welte T, Vogelmeier CF, Alter P; COSYCONET Study Group.´Int J Chron Obstruct Pulmon Dis. 2021 Nov 24;16:3189-3199. doi: 10.2147/COPD.S335029. eCollection 2021. PMID: 34853511 Free PMC article.

Woche 46 (15.11.-21.11.)

Rationale and design of the CRAFT (Continuous ReAssessment with Flexible ExTension in Rare Malignancies) multicenter phase II trial. Heilig CE, Horak P, Kreutzfeldt S, Teleanu V, Mock A, Renner M, Bhatti IA, Hutter B, Hüllein J, Fröhlich M, Uhrig S, Süße H, Heiligenthal L, Ochsenreither S, Illert AL, Vogel A, Desuki A, Heinemann V, Heidegger S, Bitzer M, Scheytt M, Brors B, Hübschmann D, Baretton G, Stenzinger A, Steindorf K, Benner A, Jäger D, Heining C, Glimm H, Fröhling S, Schlenk RF. ESMO Open. 2021 Nov 19;6(6):100310. doi: 10.1016/j.esmoop.2021.100310. Online ahead of print. PMID: 34808524

Stress, depression, sleep problems and unmet social needs: Baseline characteristics of low-income smokers in a randomized cessation trial. Garg R, McQueen A, Roberts C, Butler T, Grimes LM, Thompson T, Caburnay C, Wolff J, Javed I, Carpenter KM, Wartts JG, Charles C, Howard V, Kreuter MW. Contemp Clin Trials Commun. 2021 Nov 11;24:100857. doi: 10.1016/j.conctc.2021.100857. eCollection 2021 Dec. PMID: 34849423 Free PMC article.

Tepotinib Efficacy and Safety in Patients with MET Exon 14 Skipping NSCLC: Outcomes in Patient Subgroups from the VISION Study with Relevance for Clinical Practice. Le X, Sakai H, Felip E, Veillon R, Garassino MC, Raskin J, Cortot AB, Viteri S, Mazieres J, Smit EF, Thomas M, Iams WT, Cho BC, Kim HR, Yang JC, Chen YM, Patel JD, Bestvina CM, Park K, Griesinger F, Johnson M, Gottfried M, Britschgi C, Heymach J, Sikoglu E, Berghoff K, Schumacher KM, Bruns R, Otto G, Paik PK. Clin Cancer Res. 2021 Nov 17:clincanres.2733.2021. doi: 10.1158/1078-0432.CCR-21-2733. Online ahead of print. PMID: 34789481

Genetic landscape of patients with ALK-rearranged non-small-cell lung cancer (NSCLC) and response to ceritinib in ASCEND-1 study. Tan DS, Thomas M, Kim DW, Szpakowski S, Urban P, Mehra R, Chow LQM, Sharma S, Solomon BJ, Felip E, Camidge DR, Vansteenkiste J, Petruzzelli L, Pantano S, Shaw AT. Lung Cancer. 2021 Nov 20;163:7-13. doi: 10.1016/j.lungcan.2021.11.007. Online ahead of print. PMID: 34890832

Woche 45 (08.11.-14.11.)

Liquid Biopsies beyond Mutation Calling: Genomic and Epigenomic Features of Cell-Free DNA in Cancer. Angeles AK, Janke F, Bauer S, Christopoulos P, Riediger AL, Sültmann H.Cancers (Basel). 2021 Nov 10;13(22):5615. doi: 10.3390/cancers13225615. PMID: 34830770 Review.

Final results of the southwest German pilot study on cystic fibrosis newborn screening - Evaluation of an IRT/PAP protocol with IRT-dependent safety net: Results of the Southwest German CFNBS pilot study. Sommerburg O, Stahl M, Hämmerling S, Gramer G, Muckenthaler MU, Okun J, Kohlmüller D, Happich M, Kulozik AE, Mall MA, Hoffmann GF. J Cyst Fibros. 2021 Nov 8:S1569-1993(21)02109-3. doi: 10.1016/j.jcf.2021.10.007. Online ahead of print. PMID: 34764021

Woche 44 (01.11.-07.11.)

Alpha 1 Antitrypsin Therapy in Patients with Alpha 1 Antitrypsin Deficiency: Perspectives from a Registry Study and Practical Considerations for Self-Administration During the COVID-19 Pandemic. Herth FJF, Sandhaus RA, Turner AM, Sucena M, Welte T, Greulich T. Int J Chron Obstruct Pulmon Dis. 2021 Nov 1;16:2983-2996. doi: 10.2147/COPD.S325211. eCollection 2021. PMID: 34754184 Free PMC article. Review.

COMPERA 2.0: A refined 4-strata risk assessment model for pulmonary arterial hypertension. Hoeper MM, Pausch C, Olsson KM, Huscher D, Pittrow D, Grünig E, Staehler G, Vizza CD, Gall H, Distler O, Opitz C, Gibbs JSR, Delcroix M, Ghofrani HA, Park DH, Ewert R, Kaemmerer H, Kabitz HJ, Skowasch D, Behr J, Milger K, Halank M, Wilkens H, Seyfarth HJ, Held M, Dumitrescu D, Tsangaris I, Vonk-Noordegraaf A, Ulrich S, Klose H, Claussen M, Lange TJ, Rosenkranz S. Eur Respir J. 2021 Nov 4:2102311. doi: 10.1183/13993003.02311-2021. Online ahead of print. PMID: 34737226

Visualization of Ectopic Serine Protease Activity by Förster Resonance Energy Transfer-Based Reportersv. Rickert-Zacharias V, Schultz M, Mall MA, Schultz C. ACS Chem Biol. 2021 Nov 2. doi: 10.1021/acschembio.1c00168. Online ahead of print. PMID: 34726893

Reply to: Contrast Enhanced Magnetic Resonance Imaging Does Not Detect a Progression in Lung Morphological Score in Preschool Children with Cystic Fibrosis. Stahl M, Steinke E, Wielpütz MO, Mall MA; all authors of “Magnetic Resonance Imaging Detects Progression of Lung Disease and Impact of Newborn Screening in Preschool Children with Cystic Fibrosis”. Am J Respir Crit Care Med. 2021 Nov 3. doi: 10.1164/rccm.202109-2050LE. Online ahead of print. PMID: 34731591 No abstract available.

Recurrent YAP1-TFE3 Gene Fusions in Clear Cell Stromal Tumor of the Lung. Agaimy A, Stoehr R, Michal M, Christopoulos P, Winter H, Zhang L, Stenzinger A, Michal M, Mechtersheimer G, Antonescu CR. Am J Surg Pathol. 2021 Nov 1;45(11):1541-1549. doi: 10.1097/PAS.0000000000001719. PMID: 33899786

Prognostic impact of hypochromic erythrocytes in patients with pulmonary arterial hypertension. Xanthouli P, Theobald V, Benjamin N, Marra AM, D'Agostino A, Egenlauf B, Shaukat M, Ding C, Cittadini A, Bossone E, Kögler M, Grünig E, Muckenthaler MU, Eichstaedt CA. Respir Res. 2021 Nov 9;22(1):288. doi: 10.1186/s12931-021-01884-9. PMID: 34753505 Free PMC article.

Woche 43 (25.10.-31.10.)

Severe dysbiosis and specific Haemophilus and Neisseria signatures as hallmarks of the oropharyngeal microbiome in critically ill COVID-19 patients. de Castilhos J, Zamir E, Hippchen T, Rohrbach R, Schmidt S, Hengler S, Schumacher H, Neubauer M, Kunz S, Müller-Esch T, Hiergeist A, Gessner A, Khalid D, Gaiser R, Cullin N, Papagiannarou SM, Beuthien-Baumann B, Krämer A, Bartenschlager R, Jäger D, Müller M, Herth F, Duerschmied D, Schneider J, Schmid RM, Eberhardt JF, Khodamoradi Y, Vehreschild MJGT, Teufel A, Ebert MP, Hau P, Salzberger B, Schnitzler P, Poeck H, Elinav E, Merle U, Stein-Thoeringer CK. Clin Infect Dis. 2021 Oct 25:ciab902. doi: 10.1093/cid/ciab902. Online ahead of print. PMID: 34694375

Full recovery of right ventricular systolic function in children undergoing bilateral lung transplantation for severe PAH. Hansmann G, Diekmann F, Chouvarine P, Ius F, Carlens J, Schwerk N, Warnecke G, Vogel-Claussen J, Hohmann D, Alten T, Jack T. J Heart Lung Transplant. 2021 Oct 29:S1053-2498(21)02568-7. doi: 10.1016/j.healun.2021.10.014. Online ahead of print. PMID: 34955331

Evaluation of Transbronchial Lung Cryobiopsy Freezing Time, Biopsy Size, Histological Quality, and Incidence of Complication: A Prospective Clinical Trial. Li Y, Wei J, Jiang J, Ao Z, Yi X, Li X, Zhu X, Xiao Y, Herth FJF, Guo S. Respiration. 2021 Oct 27:1-8. doi: 10.1159/000519279. Online ahead of print. PMID: 34706367

COVID-19 pneumonia imaging follow-up: when and how? A proposition from ESTI and ESR.  Martini K, Larici AR, Revel MP, Ghaye B, Sverzellati N, Parkar AP, Snoeckx A, Screaton N, Biederer J, Prosch H, Silva M, Brady A, Gleeson F, Frauenfelder T; European Society of Thoracic Imaging (ESTI), the European Society of Radiology (ESR). Eur Radiol. 2021 Oct 29:1-11. doi: 10.1007/s00330-021-08317-7. Online ahead of print. PMID: 34713328 Free PMC article.

Role of total lung stress on the progression of early COVID-19 pneumonia: collinearity and potential confounders.  Neetz B, Meis J, Herth FJF, Trudzinski FC. Intensive Care Med. 2021 Oct 27:1-2. doi: 10.1007/s00134-021-06557-1. Online ahead of print. PMID: 34705080 Free PMC article. No abstract available.

Woche 42 (18.10.-24.10.)

COVID-19 pneumonia and its lookalikes: How radiologists perform in differentiating atypical pneumonias. Giannakis A, Móré D, Erdmann S, Kintzelé L, Fischer RM, Vogel MN, Mangold DL, von Stackelberg O, Schnitzler P, Zimmermann S, Heussel CP, Kauczor HU, Hellbach K. Eur J Radiol. 2021 Oct 19;144:110002. doi: 10.1016/j.ejrad.2021.110002. Online ahead of print. PMID: 34700092 Free PMC article.

Pirfenidone vs. nintedanib in patients with idiopathic pulmonary fibrosis: a retrospective cohort study. Marijic P, Schwarzkopf L, Schwettmann L, Ruhnke T, Trudzinski F, Kreuter M. Respir Res. 2021 Oct 19;22(1):268. doi: 10.1186/s12931-021-01857-y. PMID: 34666765

A Drug-Drug Interaction Study to Investigate the Effect of Nintedanib on the Pharmacokinetics of Microgynon (Ethinylestradiol and Levonorgestrel) in Female Patients with Systemic Sclerosis-Associated Interstitial Lung Disease. Vonk MC, Guillén-Del-Castillo A, Kreuter M, Avis M, Marzin K, Mack SR, Wind S, Gahlemann M. Eur J Drug Metab Pharmacokinet. 2021 Oct 18. doi: 10.1007/s13318-021-00728-7. Online ahead of print. PMID: 34664183

Woche 41 (11.10.-17.10.)

Artificial Intelligence for Interstitial Lung Disease: Proudly Supporting Radiologists Since 2021. Wielpütz MO. Radiology. 2021 Oct 12:210731. doi: 10.1148/radiol.2021210731. Online ahead of print. PMID: 34636638 No abstract available.

Woche 40 (04.10.-10.10.)

Prevention of Acute Exacerbation of Chronic Obstructive Pulmonary Disease after Bronchoscopic Lung Volume Reduction with Endobronchial Valves. Abia-Trujillo D, Lee-Mateus AY, Garcia-Saucedo JC, Saifi O, Patel NM, Herth FJF, Woytanowski JR, Alshelli I, Alevas S, Uribe Becerra JP, Majid A, Edell ES, Dulohery-Scrodin MM, Reisenauer JS, Mehta HJ, Jantz MA, Abbas HK, Fernandez-Bussy S. Clin Respir J. 2021 Oct 4. doi: 10.1111/crj.13450. Online ahead of print. PMID: 34605606

Three- Versus Two-Drug Therapy for Patients With Newly Diagnosed Pulmonary Arterial Hypertension. Chin KM, Sitbon O, Doelberg M, Feldman J, Gibbs JSR, Grünig E, Hoeper MM, Martin N, Mathai SC, McLaughlin VV, Perchenet L, Poch D, Saggar R, Simonneau G, Galiè N. J Am Coll Cardiol. 2021 Oct 5;78(14):1393-1403. doi: 10.1016/j.jacc.2021.07.057. PMID: 34593120

Woche 39 (27.09.-03.10.)

FAP and FAPI-PET/CT in Malignant and Non-Malignant Diseases: A Perfect Symbiosis? Dendl K, Koerber SA, Kratochwil C, Cardinale J, Finck R, Dabir M, Novruzov E, Watabe T, Kramer V, Choyke PL, Haberkorn U, Giesel FL. Cancers (Basel). 2021 Sep 30;13(19):4946. doi: 10.3390/cancers13194946. PMID: 34638433 Free PMC article. Review.

Management of Acute Exacerbation of Idiopathic Pulmonary Fibrosis in Specialised and Non-specialised ILD Centres Around the World.  Polke M, Kondoh Y, Wijsenbeek M, Cottin V, Walsh SLF, Collard HR, Chaudhuri N, Avdeev S, Behr J, Calligaro G, Corte TJ, Flaherty K, Funke-Chambour M, Kolb M, Krisam J, Maher TM, Molina Molina M, Morais A, Moor CC, Morisset J, Pereira C, Quadrelli S, Selman M, Tzouvelekis A, Valenzuela C, Vancheri C, Vicens-Zygmunt V, Wälscher J, Wuyts W, Bendstrup E, Kreuter M. Front Med (Lausanne). 2021 Sep 27;8:699644. doi: 10.3389/fmed.2021.699644. eCollection 2021. PMID: 34646836 Free PMC article.

Aligning tumor mutational burden (TMB) quantification across diagnostic platforms: phase II of the Friends of Cancer Research TMB Harmonization Project. Vega DM, Yee LM, McShane LM, Williams PM, Chen L, Vilimas T, Fabrizio D, Funari V, Newberg J, Bruce LK, Chen SJ, Baden J, Carl Barrett J, Beer P, Butler M, Cheng JH, Conroy J, Cyanam D, Eyring K, Garcia E, Green G, Gregersen VR, Hellmann MD, Keefer LA, Lasiter L, Lazar AJ, Li MC, MacConaill LE, Meier K, Mellert H, Pabla S, Pallavajjalla A, Pestano G, Salgado R, Samara R, Sokol ES, Stafford P, Budczies J, Stenzinger A, Tom W, Valkenburg KC, Wang XZ, Weigman V, Xie M, Xie Q, Zehir A, Zhao C, Zhao Y, Stewart MD, Allen J; TMB Consortium. Ann Oncol. 2021 Dec;32(12):1626-1636. doi: 10.1016/j.annonc.2021.09.016. Epub 2021 Oct 1. PMID: 34606929 Clinical Trial.

Woche 38 (20.09.-26.09.)

CT Angiography Clot Burden Score from Data Mining of Structured Reports for Pulmonary Embolism. Fink MA, Mayer VL, Schneider T, Seibold C, Stiefelhagen R, Kleesiek J, Weber TF, Kauczor HU. Radiology. 2021 Sep 28:211013. doi: 10.1148/radiol.2021211013. Online ahead of print. PMID: 34581626

[Modern tumor therapy and its pulmonary side effects].  Hellbach K. Radiologe. 2021 Oct;61(10):955-967. doi: 10.1007/s00117-021-00912-5. Epub 2021 Sep 22. PMID: 34550423 Free PMC article. German.

Quantification of pulmonary perfusion abnormalities using DCE-MRI in COPD: comparison with quantitative CT and pulmonary function. Schiwek M, Triphan SMF, Biederer J, Weinheimer O, Eichinger M, Vogelmeier CF, Jörres RA, Kauczor HU, Heußel CP, Konietzke P, von Stackelberg O, Risse F, Jobst BJ, Wielpütz MO; COSYCONET study group. Eur Radiol. 2021 Sep 22. doi: 10.1007/s00330-021-08229-6. Online ahead of print. PMID: 34553255

[Focus ventilation, oxygen therapy and weaning : Intensive medical care studies from 2020/2021]. Fiedler MO, Reuß CJ, Bernhard M, Beynon C, Hecker A, Jungk C, Nusshag C, Michalski D, Brenner T, Weigand MA, Dietrich M. Anaesthesist. 2021 Nov;70(11):967-976. doi: 10.1007/s00101-021-00979-8. Epub 2021 Oct 6. PMID: 34613457 Free PMC article. German. No abstract available.

Woche 37 (13.09.-19.09.)

[When to Test in Biomarker-stratified Therapy of Non-small Cell Lung Cancer - Biomarker-stratified Therapy of Non-small Cell Lung Cancer: When and What to Test?]. Griesinger F, Thomas M. Pneumologie. 2021 Sep;75(9):641-643. doi: 10.1055/a-1486-9057. Epub 2021 Sep 15.PMID: 34525486 German.

A New Tool to Assess Quality of Life in Patients with Idiopathic Pulmonary Fibrosis or Non-specific Interstitial Pneumonia. Kirsten D, de Vries U, Costabel U, Koschel D, Bonella F, Günther A, Behr J, Claussen M, Schwarz S, Prasse A, Kreuter M. Pneumologie. 2021 Sep 14. doi: 10.1055/a-1579-7618. Online ahead of print. PMID: 34521147 English.

Rate of lung function decline slows in the 3 years after targeted lung denervation in COPD.  Hartman JE, Conway F, Degano B, Augustijn SWS, Herth FJF, Mayr A, Chacaroun S, Tonkin J, Valipour A, Slebos DJ. Respir Med. 2021 Sep 14;188:106604. doi: 10.1016/j.rmed.2021.106604. Online ahead of print. PMID: 34543847 No abstract available.

ERS/EAACI statement on adherence to international adult asthma guidelines. Mathioudakis AG, Tsilochristou O, Adcock IM, Bikov A, Bjermer L, Clini E, Flood B, Herth F, Horvath I, Kalayci O, Papadopoulos NG, Ryan D, Sanchez Garcia S, Correia-de-Sousa J, Tonia T, Pinnock H, Agache I, Janson C. Eur Respir Rev. 2021 Sep 15;30(161):210132. doi: 10.1183/16000617.0132-2021. Print 2021 Sep 30. PMID: 34526316

Woche 36 (06.09.-12.09.)

[Treatment of lung fibrosis in systemic rheumatic diseases (new treatment)]. Buschulte K, Hoffmann-Vold AM, Dobrota RD, Höger P, Krause A, Kreuter M. Z Rheumatol. 2021 Oct;80(8):743-754. doi: 10.1007/s00393-021-01067-3. Epub 2021 Sep 10. PMID: 34505934 Free PMC article. German.

Prediction of lung emphysema in COPD by spirometry and clinical symptoms: results from COSYCONET. Kellerer C, Jörres RA, Schneider A, Alter P, Kauczor HU, Jobst B, Biederer J, Bals R, Watz H, Behr J, Kauffmann-Guerrero D, Lutter J, Hapfelmeier A, Magnussen H, Trudzinski FC, Welte T, Vogelmeier CF, Kahnert K. Respir Res. 2021 Sep 9;22(1):242. doi: 10.1186/s12931-021-01837-2. PMID: 34503520 Free PMC article.

Interstitial lung diseases: quo vadis? Kreuter M, Hoffmann-Vold AM, Bendstrup E. Lancet Respir Med. 2021 Sep 6:S2213-2600(21)00403-3. doi: 10.1016/S2213-2600(21)00403-3. Online ahead of print. PMID: 34499873 No abstract available.

Simultaneous targeting of TGF-β/PD-L1 synergizes with radiotherapy by reprogramming the tumor microenvironment to overcome immune evasion. Lan Y, Moustafa M, Knoll M, Xu C, Furkel J, Lazorchak A, Yeung TL, Hasheminasab SM, Jenkins MH, Meister S, Yu H, Schlegel J, Marelli B, Tang Z, Qin G, Klein C, Qi J, Zhou C, Locke G, Krunic D, Derner MG, Schwager C, Fontana RE, Kriegsmann K, Jiang F, Rein K, Kriegsmann M, Debus J, Lo KM, Abdollahi A. Cancer Cell. 2021 Oct 11;39(10):1388-1403.e10. doi: 10.1016/j.ccell.2021.08.008. Epub 2021 Sep 9. PMID: 34506739

Hyperthermic Intrathoracic Chemotherapy (HITOC) after Cytoreductive Surgery for Pleural Malignancies-A Retrospective, Multicentre Study. Ried M, Kovács J, Markowiak T, Müller K, Huppertz G, Koller M, Winter H, Klotz LV, Hatz R, Zimmermann J, Passlick B, Schmid S, Hassan M, Eichhorn ME, Hofmann HS. Cancers (Basel). 2021 Sep 12;13(18):4580. doi: 10.3390/cancers13184580. PMID: 34572806 Free PMC article.

Woche 35 (30.08.-05.09.)

Increased Inflammatory Markers Detected in Nasal Lavage Correlate with Paranasal Sinus Abnormalities at MRI in Adolescent Patients with Cystic Fibrosis.  Chung J, Wünnemann F, Salomon J, Boutin S, Frey DL, Albrecht T, Joachim C, Eichinger M, Mall MA, Wielpütz MO, Sommerburg O. Antioxidants (Basel). 2021 Sep 3;10(9):1412. doi: 10.3390/antiox10091412. PMID: 34573044 Free PMC article.

Survival after inpatient or outpatient pulmonary rehabilitation in patients with fibrotic interstitial lung disease: a multicentre retrospective cohort study. Guler SA, Hur SA, Stickland MK, Brun P, Bovet L, Holland AE, Bondarenko J, Hambly N, Wald J, Makhdami N, Kreuter M, Gloeckl R, Jarosch I, Tan B, Johannson KA, McBride SA, De Boer K, Sandoz JS, Sun K, Assayag D, Bhatt SP, Morisset J, Ferraro V, Garvey C, Camp PG, Ryerson CJ. Thorax. 2021 Aug 30:thoraxjnl-2021-217361. doi: 10.1136/thoraxjnl-2021-217361. Online ahead of print. PMID: 34462346

The immune microenvironment in EGFR- and ERBB2-mutated lung adenocarcinoma. Kirchner M, Kluck K, Brandt R, Volckmar AL, Penzel R, Kazdal D, Endris V, Neumann O, Seker-Cin H, Goldschmid H, Glade J, Allgäuer M, Kriegsmann M, Winter H, Muley T, Perner S, Frost N, Reck M, Fröhling S, Schirmacher P, Thomas M, Budczies J, Christopoulos P, Stenzinger A. ESMO Open. 2021 Oct;6(5):100253. doi: 10.1016/j.esmoop.2021.100253. Epub 2021 Sep 3. PMID: 34487971 Free PMC article.

Association of the advanced lung cancer inflammation index (ALI) with immune checkpoint inhibitor efficacy in patients with advanced non-small-cell lung cancer. Mountzios G, Samantas E, Senghas K, Zervas E, Krisam J, Samitas K, Bozorgmehr F, Kuon J, Agelaki S, Baka S, Athanasiadis I, Gaissmaier L, Elshiaty M, Daniello L, Christopoulou A, Pentheroudakis G, Lianos E, Linardou H, Kriegsmann K, Kosmidis P, El Shafie R, Kriegsmann M, Psyrri A, Andreadis C, Fountzilas E, Heussel CP, Herth FJ, Winter H, Emmanouilides C, Oikonomopoulos G, Meister M, Muley T, Bischoff H, Saridaki Z, Razis E, Perdikouri EI, Stenzinger A, Boukovinas I, Reck M, Syrigos K, Thomas M, Christopoulos P. ESMO Open. 2021 Oct;6(5):100254. doi: 10.1016/j.esmoop.2021.100254. Epub 2021 Sep 1. PMID: 34481329 Free PMC article.

Worldwide experiences and opinions of healthcare providers on eHealth for patients with interstitial lung diseases in the COVID-19 era. Nakshbandi G, Moor CC, Johannson KA, Maher TM, Kreuter M, Wijsenbeek MS. ERJ Open Res. 2021 Aug 31;7(3):00405-2021. doi: 10.1183/23120541.00405-2021. eCollection 2021 Jul. PMID: 34471631 Free PMC article.

Woche 34 (23.08.-29.08.)

Impact of the COVID-19 pandemic on the behaviour and health status of patients with COPD: results from the German COPD cohort COSYCONET.

Kahnert K, Lutter JI, Welte T, Alter P, Behr J, Herth F, Kauczor HU, Söhler S, Pfeifer M, Watz H, Vogelmeier CF, Bals R, Jörres RA, Trudzinski FC. ERJ Open Res. 2021 Aug 23;7(3):00242-2021. doi: 10.1183/23120541.00242-2021. eCollection 2021 Jul. PMID: 34430659 Free PMC article.

[Linguistic Validation of the "German Lung Fibrosis Health Related Quality of Life Questionnaire"]. Kirsten D, de Vries U, Costabel U, Koschel D, Bonella F, Günther A, Behr J, Claussen M, Schwarz S, Prasse A, Kreuter M. Pneumologie. 2021 Oct;75(10):753-760. doi: 10.1055/a-1334-2745. Epub 2021 Aug 24. PMID: 34428830 German.

One-step closer to solve the mystery of predicting disease progression in systemic sclerosis associated interstitial lung disease? Hoffmann-Vold AM, Kreuter M. Thorax. 2021 Aug 26:thoraxjnl-2021-217811. doi: 10.1136/thoraxjnl-2021-217811. Online ahead of print. PMID: 34446525 No abstract available.

Woche 33 (16.08.-22.08.)

Hidden Treasures: Macrophage Long Non-Coding RNAs in Lung Cancer Progression.v Karger A, Nandigama R, Stenzinger A, Grimminger F, Pullamsetti SS, Seeger W, Savai R. Cancers (Basel). 2021 Aug 17;13(16):4127. doi: 10.3390/cancers13164127. PMID: 34439281 Free PMC article. Review.

18F-labeled tracers targeting fibroblast activation protein.  Lindner T, Altmann A, Giesel F, Kratochwil C, Kleist C, Krämer S, Mier W, Cardinale J, Kauczor HU, Jäger D, Debus J, Haberkorn U. EJNMMI Radiopharm Chem. 2021 Aug 21;6(1):26. doi: 10.1186/s41181-021-00144-x. PMID: 34417894

Disease-related blood-based differential methylation in cystic fibrosis and its representation in lung cancer revealed a regulatory locus in PKP3 in lung epithelial cells. Schamschula E, Lahnsteiner A, Assenov Y, Hagmann W, Zaborsky N, Wiederstein M, Strobl A, Stanke F, Muley T, Plass C, Tümmler B, Risch A. Epigenetics. 2021 Aug 20:1-24. doi: 10.1080/15592294.2021.1959976. Online ahead of print. PMID: 34415821

Sarcopenia on preoperative chest computed tomography predicts cancer-specific and all-cause mortality following pneumonectomy for lung cancer: A multicenter analysis. Troschel FM, Jin Q, Eichhorn F, Muley T, Best TD, Leppelmann KS, Yang CJ, Troschel AS, Winter H, Heußel CP, Gaissert HA, Fintelmann FJ. Cancer Med. 2021 Aug 19. doi: 10.1002/cam4.4207. Online ahead of print. PMID: 34409756

Woche 32 (09.08.-15.08.)

Cell-to-cell variability in JAK2/STAT5 pathway components and cytoplasmic volumes defines survival threshold in erythroid progenitor cells. Adlung L, Stapor P, Tönsing C, Schmiester L, Schwarzmüller LE, Postawa L, Wang D, Timmer J, Klingmüller U, Hasenauer J, Schilling M. Cell Rep. 2021 Aug 10;36(6):109507. doi: 10.1016/j.celrep.2021.109507. PMID: 34380040

Cytoreductive Thoracic Surgery Combined with Hyperthermic Chemoperfusion for Pleural Malignancies: A Single-Center Experience. Klotz LV, Gruenewald C, Bulut EL, Eichhorn F, Thomas M, Shah R, Kriegsmann M, Schmidt W, Kofler O, Winter H, Eichhorn ME. Respiration. 2021 Aug 12:1-9. doi: 10.1159/000517334. Online ahead of print. PMID: 34384085

Pulmonary vascular resistance predicts mortality in patients with pulmonary hypertension associated with interstitial lung disease: results from the COMPERA registry. Olsson KM, Hoeper MM, Pausch C, Grünig E, Huscher D, Pittrow D, Rosenkranz S, Gall H. Eur Respir J. 2021 Aug 12:2101483. doi: 10.1183/13993003.01483-2021. Online ahead of print. PMID: 34385266

Subclinical cardiac impairment relates to traditional pulmonary function test parameters and lung volume as derived from whole-body MRI in a population-based cohort study. von Krüchten R, Lorbeer R, Schuppert C, Storz C, Mujaj B, Schulz H, Kauczor HU, Peters A, Bamberg F, Karrasch S, Schlett CL. Sci Rep. 2021 Aug 9;11(1):16173. doi: 10.1038/s41598-021-95655-7. PMID: 34373570 Free PMC article

Woche 31 (02.08.-08.08.)

In Search of a Sensor: How Does CO2 Regulate Alveolar Ion Transport? Baloğlu E, Mairbäurl H. Am J Respir Cell Mol Biol. 2021 Aug 4. doi: 10.1165/rcmb.2021-0270ED. Online ahead of print. PMID: 34348088 No abstract available.

FAP imaging in rare cancer entities-first clinical experience in a broad spectrum of malignancies. Dendl K, Finck R, Giesel FL, Kratochwil C, Lindner T, Mier W, Cardinale J, Kesch C, Röhrich M, Rathke H, Gampp H, Ristau J, Adeberg S, Jäger D, Debus J, Haberkorn U, Koerber SA. Eur J Nucl Med Mol Imaging. 2021 Aug 3. doi: 10.1007/s00259-021-05488-9. Online ahead of print. PMID: 34342669

Cost drivers in the pharmacological treatment of interstitial lung disease. Maqhuzu PN, Kreuter M, Bahmer T, Kahn N, Claussen M, Holle R, Schwarzkopf L. Respir Res. 2021 Aug 3;22(1):218. doi: 10.1186/s12931-021-01807-8. PMID: 34344376 Free PMC article.

[Exacerbation in Idiopathic Pulmonary Fibrosis]. Polke M, Kahn N, Kreuter M. Pneumologie. 2021 Aug;75(8):601-610. doi: 10.1055/a-1273-4105. Epub 2021 Aug 9. PMID: 34374062 German.

Efficacy of Immune Checkpoint Inhibitors Alone or in Combination With Chemotherapy in NSCLC Harboring ERBB2 Mutations. Saalfeld FC, Wenzel C, Christopoulos P, Merkelbach-Bruse S, Reissig TM, Laßmann S, Thiel S, Stratmann JA, Marienfeld R, Berger J, Desuki A, Velthaus JL, Kauffmann-Guerrero D, Stenzinger A, Michels S, Herold T, Kramer M, Herold S, Tufman A, Loges S, Alt J, Joosten M, Schmidtke-Schrezenmeier G, Sebastian M, Stephan-Falkenau S, Waller CF, Wiesweg M, Wolf J, Thomas M, Aust DE, Wermke M; National Network Genomic Medicine Lung Cancer (nNGM). J Thorac Oncol. 2021 Nov;16(11):1952-1958. doi: 10.1016/j.jtho.2021.06.025. Epub 2021 Jul 8. PMID: 34245914

Controversies in EUS: Do we need miniprobes? Seifert H, Fusaroli P, Arcidiacono PG, Braden B, Herth F, Hocke M, Larghi A, Napoleon B, Rimbas M, Ungureanu BS, Sãftoiu A, Sahai AV, Dietrich CF. Endosc Ultrasound. 2021 Aug 3. doi: 10.4103/EUS-D-20-00252. Online ahead of print. PMID: 34380805

Woche 30 (26.07.-01.08.)

Gender-specific differences in COPD symptoms and their impact for the diagnosis of cardiac comorbidities. Trudzinski FC, Kellerer C, Jörres RA, Alter P, Lutter JI, Trinkmann F, Herth FJF, Frankenberger M, Watz H, Vogelmeier CF, Kauczor HU, Welte T, Behr J, Bals R, Kahnert K. Clin Res Cardiol. 2021 Jul 31. doi: 10.1007/s00392-021-01915-x. Online ahead of print. PMID: 34331588

Woche 29 (19.07.-25.07.)

Endobronchial Valve (Zephyr) Treatment in Homogeneous Emphysema: One-Year Results from the IMPACT Randomized Clinical Trial.  Eberhardt R, Slebos DJ, Herth FJF, Darwiche K, Wagner M, Ficker JH, Petermann C, Hübner RH, Stanzel F, Shargill NS, Valipour A; IMPACT Study Team. Respiration. 2021 Jul 23:1-12. doi: 10.1159/000517034. Online ahead of print. PMID: 34350884

Risk of complications rise with coronary artery disease and diabetes mellitus after endobronchial valve placement in severe heterogeneous emphysema. Fernandez-Bussy S, Kornafeld A, Labarca G, Abia-Trujillo D, Patel NM, Johnson MM, Reisenauer JS, Herth FJ. Clin Respir J. 2021 Jul 23. doi: 10.1111/crj.13426. Online ahead of print. PMID: 34302313

Precision oncology: a clinical and patient perspective. Lassen UN, Makaroff LE, Stenzinger A, Italiano A, Vassal G, Garcia-Foncillas J, Avouac B. Future Oncol. 2021 Oct;17(30):3995-4009. doi: 10.2217/fon-2021-0688. Epub 2021 Jul 19. PMID: 34278817 Review.

Magnetic Resonance Imaging Detects Progression of Lung Disease and Impact of Newborn Screening in Preschool Children with Cystic Fibrosis. Stahl M, Steinke E, Graeber SY, Joachim C, Seitz C, Kauczor HU, Eichinger M, Hämmerling S, Sommerburg O, Wielpütz MO, Mall MA. Am J Respir Crit Care Med. 2021 Jul 20. doi: 10.1164/rccm.202102-0278OC. Online ahead of print. PMID: 34283704

Woche 28 (12.07.-18.07.)

The Relevance of Small Airway Dysfunction in Asthma with Nocturnal Symptoms. Abdo M, Trinkmann F, Kirsten AM, Biller H, Pedersen F, Waschki B, Von Mutius E, Kopp M, Hansen G, Rabe KF, Bahmer T, Watz H; ALLIANCE study group. J Asthma Allergy. 2021 Jul 13;14:897-905. doi: 10.2147/JAA.S313572. eCollection 2021. PMID: 34285516 Free PMC article.

Linking Fibrotic Remodeling and Ultrastructural Alterations of Alveolar Epithelial Cells after Deletion of Nedd4-2.

Engelmann TA, Knudsen L, Leitz DHW, Duerr J, Beers MF, Mall MA, Ochs M. Int J Mol Sci. 2021 Jul 16;22(14):7607. doi: 10.3390/ijms22147607. PMID: 34299227

Fibroblast Activation Protein specific PET/CT imaging in fibrotic interstitial lung diseases and lung cancer: a translational exploratory study. Röhrich M, Leitz D, Glatting FM, Wefers AK, Weinheimer O, Flechsig P, Kahn N, Mall MA, Giesel FL, Kratochwil C, Huber PE, von Deimling A, Heußel CP, Kauczor HU, Kreuter M, Haberkorn UA. J Nucl Med. 2021 Jul 16:jnumed.121.261925. doi: 10.2967/jnumed.121.261925. Online ahead of print. PMID: 34272325

The Attitudes and Practices of Physicians Caring for Patients with Rheumatoid Arthritis-Interstitial Lung Disease: An International Survey. Solomon JJ, Swigris JJ, Kreuter M, Polke M, Aronson K, Hoffmann-Vold AM, Dellaripa PF. Rheumatology (Oxford). 2021 Jul 14:keab552. doi: 10.1093/rheumatology/keab552. Online ahead of print. PMID: 34260687

Spirometry-based reconstruction of real-time cardiac MRI: Motion control and quantification of heart-lung interactions. Röwer LM, Uelwer T, Hußmann J, Malik H, Eichinger M, Voit D, Wielpütz MO, Frahm J, Harmeling S, Klee D, Pillekamp F. Magn Reson Med. 2021 Jul 17. doi: 10.1002/mrm.28892. Online ahead of print. PMID: 34272760

Woche 27 (05.07.-11.07.)

Effect of riociguat on right ventricular function in patients with pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension. Benza RL, Ghofrani HA, Grünig E, Hoeper MM, Jansa P, Jing ZC, Kim NH, Langleben D, Simonneau G, Wang C, Busse D, Meier C, Ghio S. J Heart Lung Transplant. 2021 Jul 10:S1053-2498(21)02399-8. doi: 10.1016/j.healun.2021.06.020. Online ahead of print. PMID: 34353714

Host factors facilitating SARS-CoV-2 virus infection and replication in the lungs. Boutin S, Hildebrand D, Boulant S, Kreuter M, Rüter J, Pallerla SR, Velavan TP, Nurjadi D. Cell Mol Life Sci. 2021 Jul 5:1-24. doi: 10.1007/s00018-021-03889-5. Online ahead of print. PMID: 34223911 Free PMC article. Review.

Comprehensive Dissection of Treatment Patterns and Outcome for Patients With Metastatic Large-Cell Neuroendocrine Lung Carcinoma. Fisch D, Bozorgmehr F, Kazdal D, Kuon J, Klotz LV, Shah R, Eichhorn F, Kriegsmann M, Schneider MA, Muley T, Stenzinger A, Bischoff H, Christopoulos P. Front Oncol. 2021 Jul 8;11:673901. doi: 10.3389/fonc.2021.673901. eCollection 2021. PMID: 34307143 Free PMC article.

Global incidence and prevalence of idiopathic pulmonary fibrosis. Maher TM, Bendstrup E, Dron L, Langley J, Smith G, Khalid JM, Patel H, Kreuter M. Respir Res. 2021 Jul 7;22(1):197. doi: 10.1186/s12931-021-01791-z. PMID: 34233665 Free PMC article.

Brief Report: Efficacy of immune checkpoint inhibitors alone or in combination with chemotherapy in NSCLC harboring ERBB2 mutations. Saalfeld FC, Wenzel C, Christopoulos P, Merkelbach-Bruse S, Reissig TM, Laßmann S, Thiel S, Stratmann JA, Marienfeld R, Berger J, Desuki A, Velthaus JL, Kauffmann-Guerrero D, Stenzinger A, Michels S, Herold T, Kramer M, Herold S, Tufman A, Loges S, Alt J, Joosten M, Schmidtke-Schrezenmeier G, Sebastian M, Stephan-Falkenau S, Waller CF, Wiesweg M, Wolf J, Thomas M, Aust DE, Wermke M; nNGM Lung Cancer. J Thorac Oncol. 2021 Jul 7:S1556-0864(21)02292-9. doi: 10.1016/j.jtho.2021.06.025. Online ahead of print. PMID: 34245914

Woche 26 (28.06.-04.07.)

Efficacy of docetaxel plus ramucirumab as palliative second-line therapy following first-line chemotherapy plus immune-checkpoint-inhibitor combination treatment in patients with non-small cell lung cancer (NSCLC) UICC stage IV. Brueckl WM, Reck M, Rittmeyer A, Kollmeier J, Wesseler C, Wiest GH, Christopoulos P, Stenzinger A, Tufman A, Hoffknecht P, Ulm B, Reich F, Ficker JH, Laack E. Transl Lung Cancer Res. 2021 Jul;10(7):3093-3105. doi: 10.21037/tlcr-21-197. PMID: 34430350 Free PMC article.

Therapeutic and Prognostic Implications of Immune-Related Adverse Events in Advanced Non-Small-Cell Lung Cancer. Daniello L, Elshiaty M, Bozorgmehr F, Kuon J, Kazdal D, Schindler H, Shah R, Volckmar AL, Lusky F, Diekmann L, Liersch S, Faehling M, Muley T, Kriegsmann M, Benesova K, Stenzinger A, Thomas M, Christopoulos P. Front Oncol. 2021 Jun 29;11:703893. doi: 10.3389/fonc.2021.703893. eCollection 2021. PMID: 34268127 Free PMC article.

ERS statement on chronic thromboembolic pulmonary hypertension. Delcroix M, Torbicki A, Gopalan D, Sitbon O, Klok FA, Lang I, Jenkins D, Kim NH, Humbert M, Jais X, Vonk Noordegraaf A, Pepke-Zaba J, Brénot P, Dorfmuller P, Fadel E, Ghofrani HA, Hoeper MM, Jansa P, Madani M, Matsubara H, Ogo T, Grünig E, D'Armini A, Galie N, Meyer B, Corkery P, Meszaros G, Mayer E, Simonneau G. Eur Respir J. 2021 Jun 17;57(6):2002828. doi: 10.1183/13993003.02828-2020. Print 2021 Jun. PMID: 33334946 Review.

Pralsetinib for RET fusion-positive non-small-cell lung cancer (ARROW): a multi-cohort, open-label, phase 1/2 study. Gainor JF, Curigliano G, Kim DW, Lee DH, Besse B, Baik CS, Doebele RC, Cassier PA, Lopes G, Tan DSW, Garralda E, Paz-Ares LG, Cho BC, Gadgeel SM, Thomas M, Liu SV, Taylor MH, Mansfield AS, Zhu VW, Clifford C, Zhang H, Palmer M, Green J, Turner CD, Subbiah V. Lancet Oncol. 2021 Jul;22(7):959-969. doi: 10.1016/S1470-2045(21)00247-3. Epub 2021 Jun 9. PMID: 34118197 Clinical Trial.

An integrated multiomic and quantitative label-free microscopy-based approach to study pro-fibrotic signalling in ex vivo human precision-cut lung slices. Khan MM, Poeckel D, Halavatyi A, Zukowska-Kasprzyk J, Stein F, Vappiani J, Sevin DC, Tischer C, Zinn N, Eley JD, Gudmann NS, Muley T, Winter H, Fisher AJ, Nanthakumar CB, Bergamini G, Pepperkok R. Eur Respir J. 2021 Jul 1;58(1):2000221. doi: 10.1183/13993003.00221-2020. Print 2021 Jul. PMID: 33361096 Free PMC article.

Effects of nintedanib by inclusion criteria for progression of interstitial lung disease. Maher TM, Brown KK, Kreuter M, Devaraj A, Walsh SLF, Lancaster LH, Belloli EA, Padilla M, Behr J, Goeldner RG, Tetzlaff K, Schlenker-Herceg R, Flaherty KR; INBUILD trial investigators. Eur Respir J. 2021 Jul 1:2004587. doi: 10.1183/13993003.04587-2020. Online ahead of print. PMID: 34210788

The Role of Fibroblast Activation Protein Ligands in Oncologic PET Imaging. v Dendl K, Schlittenhardt J, Staudinger F, Kratochwil C, Altmann A, Haberkorn U, Giesel FL. PET Clin. 2021 Jul;16(3):341-351. doi: 10.1016/j.cpet.2021.03.012. PMID: 34053578 Review.

Age-changes in right ventricular function-pulmonary circulation coupling: from pediatric to adult stage in 1899 healthy subjects. The RIGHT Heart International NETwork (RIGHT-NET). Vriz O, Veldman G, Gargani L, Ferrara F, Frumento P, D'Alto M, D'Andrea A, Radaan SA, Cocchia R, Marra AM, Ranieri B, Salzano A, Stanziola AA, Voilliot D, Agoston G, Cademartiri F, Cittadini A, Kasprzak JD, Grünig E, Bandera F, Guazzi M, Rudski L, Bossone E. Int J Cardiovasc Imaging. 2021 Jul 5. doi: 10.1007/s10554-021-02330-z. Online ahead of print. PMID: 34227030

Woche 25 (21.06.-27.06.)

Brigatinib versus other second-generation ALK inhibitors as initial treatment of anaplastic lymphoma kinase positive non-small cell lung cancer with deep phenotyping: study protocol of the ABP trial. Christopoulos P, Bozorgmehr F, Brückner L, Chung I, Krisam J, Schneider MA, Stenzinger A, Eickhoff R, Mueller DW, Thomas M. BMC Cancer. 2021 Jun 28;21(1):743. doi: 10.1186/s12885-021-08460-w. PMID: 34182952 Free PMC article.

Status quo of ALK testing in lung cancer: results of an EQA scheme based on in-situ hybridization, immunohistochemistry, and RNA/DNA sequencing. Jurmeister P, Vollbrecht C, Jöhrens K, Aust D, Behnke A, Stenzinger A, Penzel R, Endris V, Schirmacher P, Fisseler-Eckhoff A, Neumann J, Kirchner T, Büttner R, Merkelbach-Bruse S, Kreipe H, Jonigk D, Jochum W, Rodriguez R, Dietel M, Horst D, Hummel M, von Laffert M.Virchows Arch. 2021 Aug;479(2):247-255. doi: 10.1007/s00428-021-03106-5. Epub 2021 Jun 25. PMID: 34173019 Free PMC article.

Woche 24 (14.06.-20.06.)

Dental Biofilm and Saliva Microbiome and Its Interplay with Pediatric Allergies. Arweiler NB, Rahmel V, Alhamwe BA, Alhamdan F, Zemlin M, Boutin S, Dalpke A, Renz H. Microorganisms. 2021 Jun 18;9(6):1330. doi: 10.3390/microorganisms9061330. PMID: 34207425 Free PMC article.

Core Cross-Linked Polymeric Micelles for Specific Iron Delivery: Inducing Sterile Inflammation in Macrophages. Bauer TA, Horvat NK, Marques O, Chocarro S, Mertens C, Colucci S, Schmitt S, Carrella LM, Morsbach S, Koynov K, Fenaroli F, Blümler P, Jung M, Sotillo R, Hentze MW, Muckenthaler MU, Barz M. Adv Healthc Mater. 2021 Jun 16:e2100385. doi: 10.1002/adhm.202100385. Online ahead of print.PMID: 34137217

Head-to-head intra-individual comparison of biodistribution and tumor uptake of 68Ga-FAPI and 18F-FDG PET/CT in cancer patients. Giesel FL, Kratochwil C, Schlittenhardt J, Dendl K, Eiber M, Staudinger F, Kessler L, Fendler WP, Lindner T, Koerber SA, Cardinale J, Sennung D, Roehrich M, Debus J, Sathekge M, Haberkorn U, Calais J, Serfling S, Buck AL. Eur J Nucl Med Mol Imaging. 2021 Jun 17. doi: 10.1007/s00259-021-05307-1. Online ahead of print. PMID: 34137945

Standardized exercise training is feasible, safe, and effective in pulmonary arterial and chronic thromboembolic pulmonary hypertension: results from a large European multicentre randomized controlled trial. Grünig E, MacKenzie A, Peacock AJ, Eichstaedt CA, Benjamin N, Nechwatal R, Ulrich S, Saxer S, Bussotti M, Sommaruga M, Ghio S, Gumbiene L, Palevičiūtė E, Jurevičienė E, Cittadini A, Stanziola AA, Marra AM, Kovacs G, Olschewski H, Barberà JA, Blanco I, Spruit MA, Franssen FME, Vonk Noordegraaf A, Reis A, Santos M, Viamonte SG, Demeyer H, Delcroix M, Bossone E, Johnson M. Eur Heart J. 2021 Jun 14;42(23):2284-2295. doi: 10.1093/eurheartj/ehaa696. PMID: 33232470 Clinical Trial.

Molecular Detection of Carbapenemases in Enterobacterales: A Comparison of Real-Time Multiplex PCR and Whole-Genome Sequencing. Probst K, Nurjadi D, Heeg K, Frede AM, Dalpke AH, Boutin S. Antibiotics (Basel). 2021 Jun 16;10(6):726. doi: 10.3390/antibiotics10060726. PMID: 34208657 Free PMC article.

Reconstruction of the miR-506-Quaking axis in Idiopathic Pulmonary Fibrosis using integrative multi-source bioinformatics. Stojanović SD, Fuchs M, Liang C, Schmidt K, Xiao K, Just A, Pfanne A, Pich A, Warnecke G, Braubach P, Petzold C, Jonigk D, Distler JHW, Fiedler J, Thum T, Kunz M. Sci Rep. 2021 Jun 14;11(1):12456. doi: 10.1038/s41598-021-89531-7. PMID: 34127686 Free PMC article.

Woche 23 (07.06.-13.06.)

Deciphering the immunosuppressive tumor microenvironment in ALK- and EGFR-positive lung adenocarcinoma. Budczies J, Kirchner M, Kluck K, Kazdal D, Glade J, Allgäuer M, Kriegsmann M, Heußel CP, Herth FJ, Winter H, Meister M, Muley T, Goldmann T, Fröhling S, Wermke M, Waller CF, Tufman A, Reck M, Peters S, Schirmacher P, Thomas M, Christopoulos P, Stenzinger A. Cancer Immunol Immunother. 2021 Jun 14. doi: 10.1007/s00262-021-02981-w. Online ahead of print. PMID: 34125345

Pralsetinib for RET fusion-positive non-small-cell lung cancer (ARROW): a multi-cohort, open-label, phase 1/2 study. Gainor JF, Curigliano G, Kim DW, Lee DH, Besse B, Baik CS, Doebele RC, Cassier PA, Lopes G, Tan DSW, Garralda E, Paz-Ares LG, Cho BC, Gadgeel SM, Thomas M, Liu SV, Taylor MH, Mansfield AS, Zhu VW, Clifford C, Zhang H, Palmer M, Green J, Turner CD, Subbiah V. Lancet Oncol. 2021 Jun 9:S1470-2045(21)00247-3. doi: 10.1016/S1470-2045(21)00247-3. Online ahead of print. PMID: 34118197

Congenital Deletion of Nedd4-2 in Lung Epithelial Cells Causes Progressive Alveolitis and Pulmonary Fibrosis in Neonatal Mice. Leitz DHW, Duerr J, Mulugeta S, Seyhan Agircan A, Zimmermann S, Kawabe H, Dalpke AH, Beers MF, Mall MA. Int J Mol Sci. 2021 Jun 7;22(11):6146. doi: 10.3390/ijms22116146. PMID: 34200296 Free PMC article.

Woche 22 (31.05.-06.06.)

Raised sputum extracellular DNA confers lung function impairment and poor symptom control in an exacerbation-susceptible phenotype of neutrophilic asthma. v Abdo M, Uddin M, Goldmann T, Marwitz S, Bahmer T, Holz O, Kirsten AM, Trinkmann F, von Mutius E, Kopp M, Hansen G, Rabe KF, Watz H, Pedersen F; ALLIANCE study group. Respir Res. 2021 Jun 3;22(1):167. doi: 10.1186/s12931-021-01759-z. PMID: 34082773

Effect of timing, technique and molecular features on brain control with local therapies in oncogene-driven lung cancer. El Shafie RA, Seidensaal K, Bozorgmehr F, Kazdal D, Eichkorn T, Elshiaty M, Weber D, Allgäuer M, König L, Lang K, Forster T, Arians N, Rieken S, Heussel CP, Herth FJ, Thomas M, Stenzinger A, Debus J, Christopoulos P. ESMO Open. 2021 Jun 2;6(3):100161. doi: 10.1016/j.esmoop.2021.100161. Online ahead of print. PMID: 34090172

Simultaneous presence of the "bullseye" and "reversed halo" sign at CT of COVID-19 pneumonia: A case report.Giannakis A, Móré D, Mangold DL, von Stackelberg O, Rubtsov R, Heussel CP, Kauczor HU, Wielpütz MO, Hellbach K. Radiol Case Rep. 2021 Jun 3. doi: 10.1016/j.radcr.2021.05.074. Online ahead of print. PMID: 34099964

[Lung cancer reduction strategies].Herth FJF.MMW Fortschr Med. 2021 Jun;163(11):46-47. doi: 10.1007/s15006-021-9958-8. PMID: 34086233 Review.

Switching to riociguat versus maintenance therapy with phosphodiesterase-5 inhibitors in patients with pulmonary arterial hypertension (REPLACE): a multicentre, open-label, randomised controlled trial. Hoeper MM, Al-Hiti H, Benza RL, Chang SA, Corris PA, Gibbs JSR, Grünig E, Jansa P, Klinger JR, Langleben D, McLaughlin VV, Meyer GMB, Ota-Arakaki J, Peacock AJ, Pulido T, Rosenkranz S, Vizza CD, Vonk-Noordegraaf A, White RJ, Chang M, Kleinjung F, Meier C, Paraschin K, Ghofrani HA, Simonneau G; REPLACE investigators. Lancet Respir Med. 2021 Jun;9(6):573-584. doi: 10.1016/S2213-2600(20)30532-4. Epub 2021 Mar 24. PMID: 33773120 Clinical Trial.

Use of a Genomic Classifier in Patients with Interstitial Lung Disease: A Systematic Review.Kheir F, Uribe Becerra JP, Bissell B, Ghazipura M, Herman D, Hon SM, Hossain T, Khor YH, Knight SL, Kreuter M, Macrea M, Mammen MJ, Martinez FJ, Poletti V, Troy L, Raghu G, Wilson KC. Ann Am Thorac Soc. 2021 Jun 2. doi: 10.1513/AnnalsATS.202102-197OC. Online ahead of print. PMID: 34077697

Expert Statement: Pneumothorax Associated with One-Way Valve Therapy for Emphysema: 2020 Update.van Dijk M, Sue R, Criner GJ, Gompelmann D, Herth FJF, Hogarth DK, Klooster K, Kocks JWH, de Oliveira HG, Shah PL, Valipour A, Slebos DJ. Respiration. 2021 Jun 1:1-10. doi: 10.1159/000516326. Online ahead of print. PMID: 34062550

Symptom Burden and Palliative Care Needs of Patients with Incurable Cancer at Diagnosis and During the Disease Course.Vogt J, Beyer F, Sistermanns J, Kuon J, Kahl C, Alt-Epping B, Stevens S, Ahlborn M, George C, Heider A, Tienken M, Loquai C, Stahlhut K, Ruellan A, Kubin T, Dietz A, Oechsle K, Mehnert-Theuerkauf A, van Oorschot B, Thomas M, Ortmann O, Engel C, Lordick F; Arbeitsgemeinschaft Palliativmedizin (APM) of the German Cancer Society (DKG). Oncologist. 2021 Jun;26(6):e1058-e1065. doi: 10.1002/onco.13751. Epub 2021 Mar 30. PMID: 33687742 Free PMC article.

Woche 21 (24.05.-30.05.)

Principles and Current Clinical Landscape of Multispecific Antibodies against Cancer.Elshiaty M, Schindler H, Christopoulos P. Int J Mol Sci. 2021 May 26;22(11):5632. doi: 10.3390/ijms22115632. PMID: 34073188 Review.

Patient-reported outcomes and patient-reported outcome measures in interstitial lung disease: where to go from here?Kalluri M, Luppi F, Vancheri A, Vancheri C, Balestro E, Varone F, Mogulkoc N, Cacopardo G, Bargagli E, Renzoni E, Torrisi S, Calvello M, Libra A, Pavone M, Bonella F, Cottin V, Valenzuela C, Wijsenbeek M, Bendstrup E; 3rd International Summit for ILD (ISILD), Erice collaborators listed below. Eur Respir Rev. 2021 May 25;30(160):210026. doi: 10.1183/16000617.0026-2021. Print 2021 Jun 30. PMID: 34039675 Review.

COPD maintenance medication is linked to left atrial size: Results from the COSYCONET cohort. Kellerer C, Kahnert K, Trudzinski FC, Lutter J, Berschneider K, Speicher T, Watz H, Bals R, Welte T, Vogelmeier CF, Jörres RA, Alter P. Respir Med. 2021 Aug-Sep;185:106461. doi: 10.1016/j.rmed.2021.106461. Epub 2021 May 29. PMID: 34116329

Consolidated lung on contrast-enhanced chest CT: the use of spectral-detector computed tomography parameters in differentiating atelectasis and pneumonia. Konietzke P, Steentoft HH, Wagner WL, Albers J, Dullin C, Skornitzke S, Stiller W, Weber TF, Kauczor HU, Wielpütz MO. Heliyon. 2021 May 26;7(5):e07066. doi: 10.1016/j.heliyon.2021.e07066. eCollection 2021 May. PMID: 34113729 Free PMC article.

Practical protocol for lung magnetic resonance imaging and common clinical indications. Sodhi KS, Ciet P, Vasanawala S, Biederer J. Pediatr Radiol. 2021 May 26:1-17. doi: 10.1007/s00247-021-05090-z. Online ahead of print. PMID: 34037828 Free PMC article. Review.

Echo Time-Dependent Observed Lung T1 in Patients With Chronic Obstructive Pulmonary Disease in Correlation With Quantitative Imaging and Clinical Indices.  Triphan SMF, Weinheimer O, Gutberlet M, Heußel CP, Vogel-Claussen J, Herth F, Vogelmeier CF, Jörres RA, Kauczor HU, Wielpütz MO, Biederer J, Jobst BJ; COSYCONET Study Group. J Magn Reson Imaging. 2021 May 28. doi: 10.1002/jmri.27746. Online ahead of print. PMID: 34050576

Woche 20 (17.05.-23.05.)

Novel FAP ligands enable improved imaging contrast in sarcoma patients due to FAPI-PET/CT. Koerber SA, Finck R, Dendl K, Uhl M, Lindner T, Kratochwil C, Röhrich M, Rathke H, Ungerechts G, Adeberg S, Herfarth K, Jaeger D, Debus J, Haberkorn U, Giesel FL. Eur J Nucl Med Mol Imaging. 2021 May 21. doi: 10.1007/s00259-021-05374-4. Online ahead of print. PMID: 34018010

Woche 19 (10.05.-16.05.)

Ligand engineering for theranostic applications. Altmann A, Kratochwil C, Giesel F, Haberkorn U. Curr Opin Chem Biol. 2021 May 15;63:145-151. doi: 10.1016/j.cbpa.2021.04.006. Online ahead of print. PMID: 34004409 Review.

Woche 18 (03.05.-09.05.)

[The Current Therapy of Asbestos-Associated Malignant Pleural Mesothelioma - An Expert Consensus Paper]. Aigner C, Brüning T, Eberhardt WEE, Härter M, Kaelberlah HP, Metzenmacher M, Shah R, Taube C, Thomas M. Pneumologie. 2021 May 4. doi: 10.1055/a-1404-1562. Online ahead of print. PMID: 33946118 German.

Pirfenidone in patients with progressive fibrotic interstitial lung diseases other than idiopathic pulmonary fibrosis (RELIEF): a double-blind, randomised, placebo-controlled, phase 2b trial. Behr J, Prasse A, Kreuter M, Johow J, Rabe KF, Bonella F, Bonnet R, Grohe C, Held M, Wilkens H, Hammerl P, Koschel D, Blaas S, Wirtz H, Ficker JH, Neumeister W, Schönfeld N, Claussen M, Kneidinger N, Frankenberger M, Hummler S, Kahn N, Tello S, Freise J, Welte T, Neuser P, Günther A; RELIEF investigators. Lancet Respir Med. 2021 May;9(5):476-486. doi: 10.1016/S2213-2600(20)30554-3. Epub 2021 Mar 30. PMID: 33798455 Clinical Trial.

Validation of a targeted next-generation sequencing panel for tumor mutation burden analysis: results from the Onconetwork Immuno-Oncology Consortium. Fenizia F, Alborelli I, Costa JL, Vollbrecht C, Bellosillo B, Dinjens W, Endris V, Heydt C, Leonards K, Merkelback-Bruse S, Pfarr N, van Marion R, Allen C, Chaudhary R, Gottimukkala R, Hyland F, Wong-Ho E, Jermann P, Machado JC, Hummel M, Stenzinger A, Normanno N. J Mol Diagn. 2021 May 5:S1525-1578(21)00117-3. doi: 10.1016/j.jmoldx.2021.04.008. Online ahead of print. PMID: 33964449

Safety and Performance of Transbronchial Cryobiopsy for Parenchymal Lung Lesions. Herth FJ, Mayer M, Thiboutot J, Kapp CM, Sun J, Zhang X, Herth J, Kontogianni K, Yarmus L. Chest. 2021 May 7:S0012-3692(21)00885-0. doi: 10.1016/j.chest.2021.04.063. Online ahead of print. PMID: 33971147

[Variant interpretation in molecular pathology and oncology : An introduction]. Horak P, Leichsenring J, Kreuzfeldt S, Kazdal D, Teleanu V, Endris V, Volckmar AL, Renner M, Kirchner M, Heilig CE, Neumann O, Schirmacher P, Fröhling S, Stenzinger A. Pathologe. 2021 May 3. doi: 10.1007/s00292-021-00938-5. Online ahead of print. PMID: 33938987 Review. German.

Increased monocyte count and red cell distribution width as prognostic biomarkers in patients with Idiopathic Pulmonary Fibrosis. Karampitsakos T, Torrisi S, Antoniou K, Manali E, Korbila I, Papaioannou O, Sampsonas F, Katsaras M, Vasarmidi E, Papakosta D, Domvri K, Fouka E, Organtzis I, Daniil Z, Dimeas I, Kirgou P, Gourgoulianis KI, Papanikolaou IC, Markopoulou K, Kounti G, Tsapakidou E, Papadopoulou E, Tatsis K, Gogali A, Kostikas K, Tzilas V, Chrysikos S, Papiris S, Bouros D, Kreuter M, Tzouvelekis A. Respir Res. 2021 May 5;22(1):140. doi: 10.1186/s12931-021-01725-9. PMID: 33952261 Free PMC article.

Endobronchial Coil System versus Standard-of-Care Medical Management in the Treatment of Subjects with Severe Emphysema. Klooster K, Valipour A, Marquette CH, Boutros J, Mal H, Marceau A, Shah PL, Conway F, Deslée G, Bourdin A, Pison C, Grah C, Hetzel M, Schumann C, Kessler R, Huebner RH, Skowasch D, Darwiche K, Hammerl P, Stanzel F, Bezzi M, Dutau H, Herth FJF, Slebos DJ. Respiration. 2021 May 7:1-7. doi: 10.1159/000515744. Online ahead of print. PMID: 33965944

Effects of an Interprofessional Communication Approach on Support Needs, Quality of Life, and Mood of Patients with Advanced Lung Cancer: A Randomized Trial. Krug K, Bossert J, Deis N, Krisam J, Villalobos M, Siegle A, Jung C, Hagelskamp L, Unsöld L, Jünger J, Thomas M, Wensing M. Oncologist. 2021 Aug;26(8):e1445-e1459. doi: 10.1002/onco.13790. Epub 2021 May 4. PMID: 33860592 Free PMC article. Clinical Trial.

[Patient self-inflicted lung injury (P-SILI) : From pathophysiology to clinical evaluation with differentiated management]. Neetz B, Flohr T, Herth FJF, Müller MM. Med Klin Intensivmed Notfmed. 2021 May 7:1-10. doi: 10.1007/s00063-021-00823-2. Online ahead of print. PMID: 33961061 Free PMC article. Review. German.

Transbronchial mediastinal cryobiopsy in the diagnosis of mediastinal lesions: a randomised trial. Zhang J, Guo JR, Huang ZS, Fu WL, Wu XL, Wu N, Kuebler WM, Herth FJF, Fan Y. Eur Respir J. 2021 May 6:2100055. doi: 10.1183/13993003.00055-2021. Online ahead of print. PMID: 33958432

Woche 17 (26.04.-02.05.)

Small Airway Dysfunction Links Asthma Severity with Physical Activity and Symptom Control. Abdo M, Trinkmann F, Kirsten AM, Pedersen F, Herzmann C, von Mutius E, Kopp MV, Hansen G, Waschki B, Rabe KF, Watz H, Bahmer T; ALLAINCE study group. J Allergy Clin Immunol Pract. 2021 Apr 27:S2213-2198(21)00497-9. doi: 10.1016/j.jaip.2021.04.035. Online ahead of print. PMID: 33930619

Earlier extracranial progression and shorter survival in ALK-rearranged lung cancer with positive liquid rebiopsies. Christopoulos P, Dietz S, Angeles AK, Rheinheimer S, Kazdal D, Volckmar AL, Janke F, Endris V, Meister M, Kriegsmann M, Zemojtel T, Reck M, Stenzinger A, Thomas M, Sültmann H. Transl Lung Cancer Res. 2021 May;10(5):2118-2131. doi: 10.21037/tlcr-21-32. PMID: 34164264 Free PMC article.

Suggestions for improving clinical utility of future guidelines for diagnosis and management of idiopathic pulmonary fibrosis: results of a Delphi survey. Funke-Chambour M, Albera C, Bendstrup E, Costabel U, Grutters JC, Harari S, Johannson KA, Kreuter M, Strambu I, Vancheri C, Varone F, Vitulo P, Wuyts WA, Martinez F, Raghu G; Erice participants; Erice participants:. Eur Respir J. 2021 Apr 29;57(4):2004219. doi: 10.1183/13993003.04219-2020. Print 2021 Apr. PMID: 33419886 No abstract available.

Role of Synaptophysin, Chromogranin and CD56 in adenocarcinoma and squamous cell carcinoma of the lung lacking morphological features of neuroendocrine differentiation: a retrospective large-scale study on 1170 tissue samples. Kriegsmann K, Zgorzelski C, Muley T, Christopoulos P, Thomas M, Winter H, Eichhorn M, Eichhorn F, von Winterfeld M, Herpel E, Goeppert B, Stenzinger A, Herth FJF, Warth A, Kriegsmann M. BMC Cancer. 2021 May 1;21(1):486. doi: 10.1186/s12885-021-08140-9. PMID: 33933015

68Ga-FAPI-PET/CT improves diagnostic staging and radiotherapy planning of Adenoid Cystic Carcinomas - imaging analysis and histological validation. Röhrich M, Syed M, Liew DP, Giesel FL, Liermann J, Choyke PL, Wefers AK, Ritz T, Szymbara M, Schillings L, Heger U, Rathke H, Kratochwil C, Huber PE, von Deimling A, Debus J, Kauczor HU, Haberkorn U, Adeberg S. Radiother Oncol. 2021 Apr 30:S0167-8140(21)06213-7. doi: 10.1016/j.radonc.2021.04.016. Online ahead of print. PMID: 33940087

Woche 16 (19.04.-25.04.)

Recurrent YAP1-TFE3 Gene Fusions in Clear Cell Stromal Tumor of the Lung. Agaimy A, Stoehr R, Michal M, Christopoulos P, Winter H, Zhang L, Stenzinger A, Michal M, Mechtersheimer G, Antonescu CR. Am J Surg Pathol. 2021 Apr 23. doi: 10.1097/PAS.0000000000001719. Online ahead of print. PMID: 33899786

Prognostic Impact of PD-L1 Expression in pN1 NSCLC: A Retrospective Single-Center Analysis. Eichhorn F, Kriegsmann M, Klotz LV, Kriegsmann K, Muley T, Zgorzelski C, Christopoulos P, Winter H, Eichhorn ME. Cancers (Basel). 2021 Apr 23;13(9):2046. doi: 10.3390/cancers13092046. PMID: 33922610

Feasibility and Challenges for Sequential Treatments in ALK-Rearranged Non-Small-Cell Lung Cancer. Elsayed M, Bozorgmehr F, Kazdal D, Volckmar AL, Sültmann H, Fischer JR, Kriegsmann M, Stenzinger A, Thomas M, Christopoulos P. Front Oncol. 2021 Apr 20;11:670483. doi: 10.3389/fonc.2021.670483. eCollection 2021. PMID: 33959513 Free PMC article.

Woche 15 (12.04.-18.04.)

Targeting the Notch Signaling Pathway in Chronic Inflammatory Diseases. Christopoulos PF, Gjølberg TT, Krüger S, Haraldsen G, Andersen JT, Sundlisæter E. Front Immunol. 2021 Apr 12;12:668207. doi: 10.3389/fimmu.2021.668207. eCollection 2021. PMID: 33912195 Free PMC article. Review.

Feasibility of semi-recumbent bicycle exercise Doppler echocardiography for the evaluation of the right heart and pulmonary circulation unit in different clinical conditions: the RIGHT heart international NETwork (RIGHT-NET). Ferrara F, Gargani L, Naeije R, Rudski L, Armstrong WF, Wierzbowska-Drabik K, Argiento P, Bandera F, Cademartiri F, Citro R, Cittadini A, Cocchia R, Contaldi C, D'Alto M, D'Andrea A, Grünig E, Guazzi M, Kolias TJ, Limongelli G, Marra AM, Mauro C, Moreo A, Ranieri B, Saggar R, Salzano A, Stanziola AA, Vriz O, Vannan M, Kasprzak JD, Bossone E; RIGHT Heart International NETwork (RIGHT-NET). Int J Cardiovasc Imaging. 2021 Apr 18. doi: 10.1007/s10554-021-02243-x. Online ahead of print. PMID: 33866467

Fully Automated Segmentation of Pulmonary Fibrosis Using Different Software Tools. Ley-Zaporozhan J, Giannakis A, Norajitra T, Weinheimer O, Kehler L, Dinkel J, Ganter C, Ley S, Van Lunteren C, Eichinger M, Heussel G, Kauczor HU, Maier-Hein KH, Kreuter M, Heussel CP. Respiration. 2021 Apr 15:1-8. doi: 10.1159/000515182. Online ahead of print. PMID: 33857945

Idiopathic pulmonary fibrosis beyond the lung: understanding disease mechanisms to improve diagnosis and management. Luppi F, Kalluri M, Faverio P, Kreuter M, Ferrara G. Respir Res. 2021 Apr 17;22(1):109. doi: 10.1186/s12931-021-01711-1. PMID: 33865386 Review.

A reporting and analysis framework for structured evaluation of COVID-19 clinical and imaging data. Salg GA, Ganten MK, Bucher AM, Kenngott HG, Fink MA, Seibold C, Fischbach RE, Schlamp K, Velandia CA, Fervers P, Doellinger F, Luger A, Afat S, Merle U, Diener MK, Pereira PL, Penzkofer T, Persigehl T, Othman A, Heußel CP, Baumhauer M, Widmann G, Stathopoulos K, Hamm B, Vogl TJ, Nikolaou K, Kauczor HU, Kleesiek J. NPJ Digit Med. 2021 Apr 12;4(1):69. doi: 10.1038/s41746-021-00439-y. PMID: 33846548

Woche 14 (05.04.-11.04.)

Validation of the T Descriptor (TNM-8) in T3N0 Non-Small-Cell Lung Cancer Patients; a Bicentric Cohort Analysis with Arguments for Redefinition.  Baum P, Taber S, Erdmann S, Muley T, Kriegsmann M, Christopoulos P, Thomas M, Winter H, Pfannschmidt J, Eichhorn ME. Cancers (Basel). 2021 Apr 10;13(8):1812. doi: 10.3390/cancers13081812. PMID: 33920161

De Novo Versus Secondary Metastatic EGFR-Mutated Non-Small-Cell Lung Cancer. Bozorgmehr F, Kazdal D, Chung I, Kirchner M, Magios N, Kriegsmann M, Allgäuer M, Klotz LV, Muley T, El Shafie RA, Fischer JR, Faehling M, Stenzinger A, Thomas M, Christopoulos P. Front Oncol. 2021 Apr 9;11:640048. doi: 10.3389/fonc.2021.640048. eCollection 2021. PMID: 33898315 Free PMC article.

Bedside hyperspectral imaging indicates a microcirculatory sepsis pattern - an observational study. Dietrich M, Marx S, von der Forst M, Bruckner T, Schmitt FCF, Fiedler MO, Nickel F, Studier-Fischer A, Müller-Stich BP, Hackert T, Brenner T, Weigand MA, Uhle F, Schmidt K. Microvasc Res. 2021 Jul;136:104164. doi: 10.1016/j.mvr.2021.104164. Epub 2021 Apr 6. PMID: 33831406

Woche 13 (29.03.-04.04.)

Pirfenidone in patients with progressive fibrotic interstitial lung diseases other than idiopathic pulmonary fibrosis (RELIEF): a double-blind, randomised, placebo-controlled, phase 2b trial. Behr J, Prasse A, Kreuter M, Johow J, Rabe KF, Bonella F, Bonnet R, Grohe C, Held M, Wilkens H, Hammerl P, Koschel D, Blaas S, Wirtz H, Ficker JH, Neumeister W, Schönfeld N, Claussen M, Kneidinger N, Frankenberger M, Hummler S, Kahn N, Tello S, Freise J, Welte T, Neuser P, Günther A; RELIEF investigators. Lancet Respir Med. 2021 Mar 30:S2213-2600(20)30554-3. doi: 10.1016/S2213-2600(20)30554-3. Online ahead of print. PMID: 33798455

Quantifying potential confounders of panel-based tumor mutational burden (TMB) measurement. Budczies J, Kazdal D, Allgäuer M, Christopoulos P, Rempel E, Pfarr N, Weichert W, Fröhling S, Thomas M, Peters S, Endris V, Schirmacher P, Stenzinger A. Lung Cancer. 2020 Apr;142:114-119. doi: 10.1016/j.lungcan.2020.01.019. Epub 2020 Feb 1. PMID: 32143116

Bronchoscopic performance of bronchoalveolar lavage in germany - a call for standardization. Hetzel J, Kreuter M, Kähler CM, Kabitz HJ, Gschwendtner A, Eberhardt R, Costabel U, Darwiche K. Sarcoidosis Vasc Diffuse Lung Dis. 2021;38(1):e2021003. doi: 10.36141/svdld.v38i1.10628. Epub 2021 Mar 31. PMID: 33867790 Free PMC article.

Conventional and semi-automatic histopathological analysis of tumor cell content for multigene sequencing of lung adenocarcinoma. Kazdal D, Rempel E, Oliveira C, Allgäuer M, Harms A, Singer K, Kohlwes E, Ormanns S, Fink L, Kriegsmann J, Leichsenring M, Kriegsmann K, Stögbauer F, Tavernar L, Leichsenring J, Volckmar AL, Longuespée R, Winter H, Eichhorn M, Heußel CP, Herth F, Christopoulos P, Reck M, Muley T, Weichert W, Budczies J, Thomas M, Peters S, Warth A, Schirmacher P, Stenzinger A, Kriegsmann M. Transl Lung Cancer Res. 2021 Apr;10(4):1666-1678. doi: 10.21037/tlcr-20-1168. PMID: 34012783 Free PMC article.

Addressing Social Needs in Health Care Settings: Evidence, Challenges, and Opportunities for Public Health. Kreuter MW, Thompson T, McQueen A, Garg R. Annu Rev Public Health. 2021 Apr 1;42:329-344. doi: 10.1146/annurev-publhealth-090419-102204. Epub 2021 Dec 16. PMID: 33326298 Review.

Consideration of sense of coherence in a structured communication approach with stage IV lung cancer patients and their informal caregivers: a qualitative interview study. Krug K, Bossert J, Stooß L, Siegle A, Villalobos M, Hagelskamp L, Jung C, Thomas M, Wensing M. Support Care Cancer. 2021 Apr;29(4):2153-2159. doi: 10.1007/s00520-020-05724-2. Epub 2020 Sep 3. PMID: 32880008 Free PMC article.

Personalising lung cancer screening: an overview of risk-stratification opportunities and challenges. Ten Haaf K, van der Aalst CM, de Koning HJ, Kaaks R, Tammemägi MC. Int J Cancer. 2021 Mar 30. doi: 10.1002/ijc.33578. Online ahead of print. PMID: 33783822

Targeting rare and non-canonical driver variants in NSCLC - An uncharted clinical field. Volckmar AL, Christopoulos P, Kirchner M, Allgäuer M, Neumann O, Budczies J, Rempel E, Horak P, Glade J, Goldschmid H, Seker-Cin H, Brandt R, Kriegsmann M, Leichsenring J,

Woche 12 (22.03.-28.03.)

Educational aspects of rare and orphan lung diseases. Alfaro TM, Wijsenbeek MS, Powell P, Stolz D, Hurst JR, Kreuter M, Moor CC. Respir Res. 2021 Mar 24;22(1):92. doi: 10.1186/s12931-021-01676-1. PMID: 33761959 Free PMC article. Review.

[Recommendations for Performing Bronchoscopy in Times of the COVID-19 Pandemic - Update 12/2020]. Darwiche K, Ross B, Gesierich W, Petermann C, Huebner RH, Grah C, Gompelmann D, Hetzel J, Holland A, Eisenmann S, Stanzel F, Kempa A, Conrad K, Hagmeyer L, Eberhardt R. Pneumologie. 2021 Mar;75(3):187-190. doi: 10.1055/a-1320-8250. Epub 2020 Dec 11. PMID: 33307556 German

Management of Significant Airway Bleeding during Robotic Assisted Bronchoscopy: A Tailored Approach.v Fernandez-Bussy S, Abia-Trujillo D, Majid A, Folch EE, Patel NM, Herth FJF, Reisenauer JS. Respiration. 2021 Mar 26:1-4. doi: 10.1159/000514830. Online ahead of print. PMID: 33774623

Switching to riociguat versus maintenance therapy with phosphodiesterase-5 inhibitors in patients with pulmonary arterial hypertension (REPLACE): a multicentre, open-label, randomised controlled trial. Hoeper MM, Al-Hiti H, Benza RL, Chang SA, Corris PA, Gibbs JSR, Grünig E, Jansa P, Klinger JR, Langleben D, McLaughlin VV, Meyer GMB, Ota-Arakaki J, Peacock AJ, Pulido T, Rosenkranz S, Vizza CD, Vonk-Noordegraaf A, White RJ, Chang M, Kleinjung F, Meier C, Paraschin K, Ghofrani HA, Simonneau G; REPLACE investigators. Lancet Respir Med. 2021 Mar 24:S2213-2600(20)30532-4. doi: 10.1016/S2213-2600(20)30532-4. Online ahead of print. PMID: 33773120

Case Report: Abdominal Lymph Node Metastases of Parathyroid Carcinoma: Diagnostic Workup, Molecular Diagnosis, and Clinical Management. Lenschow C, Fuss CT, Kircher S, Buck A, Kickuth R, Reibetanz J, Wiegering A, Stenzinger A, Hübschmann D, Germer CT, Fassnacht M, Fröhling S, Schlegel N, Kroiss M. Front Endocrinol (Lausanne). 2021 Mar 23;12:643328. doi: 10.3389/fendo.2021.643328. eCollection 2021. PMID: 33833736 Free PMC article.

Real-world implementation of sequential targeted therapies for EGFR-mutated lung cancer. Magios N, Bozorgmehr F, Volckmar AL, Kazdal D, Kirchner M, Herth FJ, Heussel CP, Eichhorn F, Meister M, Muley T, Elshafie RA, Fischer JR, Faehling M, Kriegsmann M, Schirmacher P, Bischoff H, Stenzinger A, Thomas M, Christopoulos P. Ther Adv Med Oncol. 2021 Mar 24;13:1758835921996509. doi: 10.1177/1758835921996509. eCollection 2021. PMID: 34408792 Free PMC article.

Effect of Supervised Training Therapy on Pulmonary Arterial Compliance and Stroke Volume in Severe Pulmonary Arterial Hypertension and Inoperable or Persistent Chronic Thromboembolic Pulmonary Hypertension. Nagel C, Benjamin N, Egenlauf B, Eichstaedt CA, Fischer C, Palevičiūtė E, Čelutkienė J, Harutyunova S, Mayer E, Nasereddin M, Marra AM, Grünig E, Guth S. Respiration. 2021 Mar 25:1-10. doi: 10.1159/000512316. Online ahead of print. PMID: 33765679

Improved detection of air trapping on expiratory computed tomography using deep learning.  Ram S, Hoff BA, Bell AJ, Galban S, Fortuna AB, Weinheimer O, Wielpütz MO, Robinson TE, Newman B, Vummidi D, Chughtai A, Kazerooni EA, Johnson TD, Han MK, Hatt CR, Galban CJ. PLoS One. 2021 Mar 24;16(3):e0248902. doi: 10.1371/journal.pone.0248902. eCollection 2021. PMID: 33760861

Natural variability in the disease course of SSc-ILD: implications for treatment. Vonk MC, Walker UA, Volkmann ER, Kreuter M, Johnson SR, Allanore Y. Eur Respir Rev. 2021 Mar 24;30(159):200340. doi: 10.1183/16000617.0340-2020. Print 2021 Mar 31. PMID: 33762426 Review.

Woche 11 (15.03.-21.03.)

Therapeutic Inhibition of Cathepsin S Reduces Inflammation and Mucus Plugging in Adult βENaC-Tg Mice. Brown R, Small DM, Doherty DF, Holsinger L, Booth R, Williams R, Ingram RJ, Elborn JS, Mall MA, Taggart CC, Weldon S. Mediators Inflamm. 2021 Mar 19;2021:6682657. doi: 10.1155/2021/6682657. eCollection 2021. PMID: 33828414 Free PMC article.

Comparing two approaches to remote biochemical verification of self-reported cessation in very low-income smokers. Garg R, McQueen A, Wolff J, Butler T, Thompson T, Caburnay C, Kreuter MW. Addict Behav Rep. 2021 Mar 17;13:100343. doi: 10.1016/j.abrep.2021.100343. eCollection 2021 Jun. PMID: 33786362 Free PMC article.

Absence of neocytolysis in humans returning from a 3-week high-altitude sojourn. Klein M, Kaestner L, Bogdanova AY, Minetti G, Rudloff S, Lundby C, Makhro A, Seiler E, van Cromvoirt A, Fenk S, Simionato G, Hertz L, Recktenwald S, Schäfer L, Haider T, Fried S, Borsch C, Marti HH, Sander A, Mairbäurl H. Acta Physiol (Oxf). 2021 Mar 17:e13647. doi: 10.1111/apha.13647. Online ahead of print. PMID: 33729672

[153Sm]Samarium-labeled FAPI-46 radioligand therapy in a patient with lung metastases of a sarcoma. Kratochwil C, Giesel FL, Rathke H, Fink R, Dendl K, Debus J, Mier W, Jäger D, Lindner T, Haberkorn U. Eur J Nucl Med Mol Imaging. 2021 Mar 17. doi: 10.1007/s00259-021-05273-8. Online ahead of print. PMID: 33728499 No abstract available.

CFTR Modulator Therapy with Lumacaftor/Ivacaftor Alters Plasma Concentrations of Lipid-Soluble Vitamins A and E in Patients with Cystic Fibrosis. Sommerburg O, Hämmerling S, Schneider SP, Okun J, Langhans CD, Leutz-Schmidt P, Wielpütz MO, Siems W, Gräber SY, Mall MA, Stahl M. Antioxidants (Basel). 2021 Mar 19;10(3):483. doi: 10.3390/antiox10030483. PMID: 33808590

Changes in the Cystic Fibrosis Airway Microbiome in Response to CFTR Modulator Therapy. Yi B, Dalpke AH, Boutin S. Front Cell Infect Microbiol. 2021 Mar 17;11:548613. doi: 10.3389/fcimb.2021.548613. eCollection 2021. PMID: 33816324 Free PMC article. Review.

Woche 10 (08.03.-14.03.)

Persistent Uncontrolled Asthma: Long-Term Impact on Physical Activity and Body Composition. Abdo M, Waschki B, Kirsten AM, Trinkmann F, Biller H, Herzmann C, von Mutius E, Kopp M, Hansen G, Rabe KF, Bahmer T, Watz H; ALLIANCE study group. J Asthma Allergy. 2021 Mar 12;14:229-240. doi: 10.2147/JAA.S299756. eCollection 2021. PMID: 33737816 Free PMC article.

Guidance on Imaging for Invasive Pulmonary Aspergillosis and Mucormycosis: From the Imaging Working Group for the Revision and Update of the Consensus Definitions of Fungal Disease from the EORTC/MSGERC. Alexander BD, Lamoth F, Heussel CP, Prokop CS, Desai SR, Morrissey CO, Baddley JW. Clin Infect Dis. 2021 Mar 12;72(Supplement_2):S79-S88. doi: 10.1093/cid/ciaa1855. PMID: 33709131

Tobacco Smoking and Risk of Second Primary Lung Cancer. Aredo JV, Luo SJ, Gardner RM, Sanyal N, Choi E, Hickey TP, Riley TL, Huang WY, Kurian AW, Leung AN, Wilkens LR, Robbins HA, Riboli E, Kaaks R, Tjønneland A, Vermeulen RCH, Panico S, Le Marchand L, Amos CI, Hung RJ, Freedman ND, Johansson M, Cheng I, Wakelee HA, Han SS. J Thorac Oncol. 2021 Mar 12:S1556-0864(21)01747-0. doi: 10.1016/j.jtho.2021.02.024. Online ahead of print. PMID: 33722709

A randomized, multicenter phase II study comparing efficacy, safety and tolerability of two dosing regimens of cisplatin and pemetrexed in patients with advanced or metastatic non-small-cell lung cancer. Metzenmacher M, Kopp HG, Griesinger F, Reinmuth N, Sebastian M, Serke M, Waller CF, Thomas M, Eggert J, Schmid-Bindert G, Hoiczyk M, Christoph DC, Kimmich M, Deuß B, Seifert S, Held S, Schuler M, Herold T, Breitenbuecher F, Eberhardt WEE. Ther Adv Med Oncol. 2021 Mar 9;13:1758835921996506. doi: 10.1177/1758835921996506. eCollection 2021. PMID: 34104223 Free PMC article.

Symptom burden and palliative care needs of patients with incurable cancer at diagnosis and during the disease course. Vogt J, Beyer F, Sistermanns J, Kuon J, Kahl C, Alt-Epping B, Stevens S, Ahlborn M, George C, Heider A, Tienken M, Loquai C, Stahlhut K, Ruellan A, Kubin T, Dietz A, Oechsle K, Mehnert-Theuerkauf A, van Oorschot B, Thomas M, Ortmann O, Engel C, Lordick F; Arbeitsgemeinschaft Palliativmedizin (APM) of the German Cancer Society (DKG). Oncologist. 2021 Mar 9. doi: 10.1002/onco.13751. Online ahead of print. PMID: 33687742

Woche 9 (01.03.-07.03.)

Diagnosis and staging of lung cancer with the use of one single echoendoscope in both the trachea and the esophagus:A practical guide. Clementsen PF, Bodtger U, Konge L, Christiansen IS, Nessar R, Salih GN, Kolekar S, Meyer CN, Colella S, Jenssen C, Herth F, Hocke M, Dietrich CF. Endosc Ultrasound. 2021 Mar 2. doi: 10.4103/EUS-D-20-00139. Online ahead of print. PMID: 33666182

Validation of multivariable lung cancer risk prediction models for the personalized assignment of optimal screening frequency: a retrospective analysis of data from the German Lung Cancer Screening Intervention Trial (LUSI).  González Maldonado S, Hynes LC, Motsch E, Heussel CP, Kauczor HU, Robbins HA, Delorme S, Kaaks R. Transl Lung Cancer Res. 2021 Mar;10(3):1305-1317. doi: 10.21037/tlcr-20-1173. PMID: 33889511 Free PMC article.

The Diagnosis and Treatment of Pulmonary Fibrosis. Kreuter M, Ladner UM, Costabel U, Jonigk D, Heussel CP. Dtsch Arztebl Int. 2021 Mar 5;118(Forthcoming):arztebl.m2021.0018. doi: 10.3238/arztebl.m2021.0018. Online ahead of print. PMID: 33531115

Genome-wide association meta-analysis identifies pleiotropic risk loci for aerodigestive squamous cell cancers. Lesseur C, Ferreiro-Iglesias A, McKay JD, Bossé Y, Johansson M, Gaborieau V, Landi MT, Christiani DC, Caporaso NC, Bojesen SE, Amos CI, Shete S, Liu G, Rennert G, Albanes D, Aldrich MC, Tardon A, Chen C, Triantafillos L, Field JK, Teare MD, Kiemeney LA, Diergaarde B, Ferris RL, Zienolddiny S, Lam S, Olshan AF, Weissler MC, Lacko M, Risch A, Bickeböller H, Ness AR, Thomas S, Le Marchand L, Schabath MB, Wünsch-Filho V, Tajara EH, Andrew AS, Clifford GM, Lazarus P, Grankvist K, Johansson M, Arnold S, Melander O, Brunnström H, Boccia S, Cadoni G, Timens W, Obeidat M, Xiao X, Houlston RS, Hung RJ, Brennan P. PLoS Genet. 2021 Mar 5;17(3):e1009254. doi: 10.1371/journal.pgen.1009254. Online ahead of print. PMID: 33667223

Concomitant mutation status of ALK-rearranged non-small cell lung cancers and its prognostic impact on patients treated with crizotinib. Li J, Zhang B, Zhang Y, Xu F, Zhang Z, Shao L, Yan C, Ulivi P, Denis MG, Christopoulos P, Thomas de Montpréville V, Bernicker EH, van der Wekken AJ, Wang C, Yue D. Transl Lung Cancer Res. 2021 Mar;10(3):1525-1535. doi: 10.21037/tlcr-21-160. PMID: 33889527 Free PMC article.

Influence of Cell Quality on Inflammatory Biomarkers in COPD Sputum Supernatant. Pedersen F, Trinkmann F, Abdo M, Kirsten AM, Rabe KF, Watz H, Baraldo S, Saetta M, Hohlfeld JM, Holz O. Int J Chron Obstruct Pulmon Dis. 2021 Mar 1;16:487-493. doi: 10.2147/COPD.S284938. eCollection 2021. PMID: 33688174 Free PMC article.

Profibrotic epithelial TGF-β1 signaling involves NOX4-mitochondria cross talk and redox-mediated activation of the tyrosine kinase FYN. Veith C, Hristova M, Danyal K, Habibovic A, Dustin CM, McDonough JE, Vanaudenaerde BM, Kreuter M, Schneider MA, Kahn N, van Schooten FJ, Boots AW, van der Vliet A. Am J Physiol Lung Cell Mol Physiol. 2021 Mar 1;320(3):L356-L367. doi: 10.1152/ajplung.00444.2019. Epub 2020 Dec 16. PMID: 33325804

Causal relationships between body mass index, smoking and lung cancer: Univariable and multivariable Mendelian randomization. Zhou W, Liu G, Hung RJ, Haycock PC, Aldrich MC, Andrew AS, Arnold SM, Bickeböller H, Bojesen SE, Brennan P, Brunnström H, Melander O, Caporaso NE, Landi MT, Chen C, Goodman GE, Christiani DC, Cox A, Field JK, Johansson M, Kiemeney LA, Lam S, Lazarus P, Le Marchand L, Rennert G, Risch A, Schabath MB, Shete SS, Tardón A, Zienolddiny S, Shen H, Amos CI. Int J Cancer. 2021 Mar 1;148(5):1077-1086. doi: 10.1002/ijc.33292. Epub 2020 Sep 23. PMID: 32914876

Woche 8 (22.02.-28.02.)

Association of proangiogenic and profibrotic serum markers with lung function and quality of life in sarcoidosis. Biener L, Kruse J, Tuleta I, Pizarro C, Kreuter M, Birring SS, Nickenig G, Skowasch D. PLoS One. 2021 Feb 22;16(2):e0247197. doi: 10.1371/journal.pone.0247197. eCollection 2021. PMID: 33617593

Versatile workflow for cell-type resolved transcriptional and epigenetic profiles from cryopreserved human lung. Llamazares Prada M, Espinet E, Mijošek V, Schwartz U, Lutsik P, Tamas R, Richter M, Behrendt A, Pohl ST, Benz NP, Muley T, Warth A, Heußel CP, Winter H, Landry JJM, Herth FJ, Mertens TC, Karmouty-Quintana H, Koch I, Benes V, Korbel JO, Waszak SM, Trumpp A, Wyatt DM, Stahl HF, Plass C, Jurkowska RZ. JCI Insight. 2021 Feb 25:140443. doi: 10.1172/jci.insight.140443. Online ahead of print. PMID: 33630765

Defining key outcomes to evaluate performance of newborn screening programmes for cystic fibrosis. Munck A, Southern KW, Castellani C, de Winter-de Groot KM, Gartner S, Kashirskaya N, Linnane B, Mayell SJ, Proesmans M, Sands D, Sommerburg O, Barben J; European CF Society Neonatal Screening Working Group (ECFS NSWG). J Cyst Fibros. 2021 Feb 23:S1569-1993(21)00041-2. doi: 10.1016/j.jcf.2021.02.006. Online ahead of print. PMID: 33637432 No abstract available.

The patient tells it! The importance of patient's quality of life perception in pulmonary arterial hypertension risk assessment. Ulrich S, Grunig E. Eur Respir J. 2021 Feb 25;57(2):2004376. doi: 10.1183/13993003.04376-2020. Print 2021 Feb. PMID: 33632888 No abstract available.

Woche 7 (15.02.-21.02.)

Differentially methylated regions within lung cancer risk loci are enriched in deregulated enhancers. Laplana M, Bieg M, Faltus C, Melnik S, Bogatyrova O, Gu Z, Muley T, Meister M, Dienemann H, Herpel E, Amos CI, Schlesner M, Eils R, Plass C, Risch A. Epigenetics. 2021 Feb 17:1-16. doi: 10.1080/15592294.2021.1878723. Online ahead of print. PMID: 33595421

Hypoxia Routes Tryptophan Homeostasis Towards Increased Tryptamine Production. Mohapatra SR, Sadik A, Sharma S, Poschet G, Gegner HM, Lanz TV, Lucarelli P, Klingmüller U, Platten M, Heiland I, Opitz CA. Front Immunol. 2021 Feb 19;12:590532. doi: 10.3389/fimmu.2021.590532. eCollection 2021. PMID: 33679737 Free PMC article.

DNA methylation profiles of bronchoscopic biopsies for the diagnosis of lung cancer. Goldmann T, Schmitt B, Müller J, Kröger M, Scheufele S, Marwitz S, Nitschkowski D, Schneider MA, Meister M, Muley T, Thomas M, Kugler C, Rabe KF, Siebert R, Reck M, Ammerpohl O. Clin Epigenetics. 2021 Feb 17;13(1):38. doi: 10.1186/s13148-021-01024-6. PMID: 33596996

Effects of Lumacaftor-Ivacaftor on Lung Clearance Index, Magnetic Resonance Imaging and Airway Microbiome in Phe508del Homozygous Patients with Cystic Fibrosis.  Graeber SY, Boutin S, Wielpütz MO, Joachim C, Frey DL, Wege S, Sommerburg O, Kauczor HU, Stahl M, Dalpke AH, Mall MA. Ann Am Thorac Soc. 2021 Feb 18. doi: 10.1513/AnnalsATS.202008-1054OC. Online ahead of print. PMID: 33600745

Chronic Rhinosinusitis with Nasal Polyps is Associated with Impaired TMEM16A-mediated Epithelial Chloride Secretion.  Salomon JJ, Albrecht T, Graeber SY, Scheuermann H, Butz S, Schatterny J, Mairbäurl H, Baumann I, Mall MA. J Allergy Clin Immunol. 2021 Feb 17:S0091-6749(21)00224-4. doi: 10.1016/j.jaci.2021.02.008. Online ahead of print. PMID: 33609628

KRAS G12C-mutated advanced non-small cell lung cancer: A real-world cohort from the German prospective, observational, nation-wide CRISP Registry (AIO-TRK-0315). Sebastian M, Eberhardt WEE, Hoffknecht P, Metzenmacher M, Wehler T, Kokowski K, Alt J, Schütte W, Büttner R, Heukamp LC, Stenzinger A, Jänicke M, Fleitz A, Zacharias S, Dille S, Hipper A, Sandberg M, Weichert W, Groschek M, von der Heyde E, Rauh J, Dechow T, Thomas M, Griesinger F; CRISP Registry Group. Lung Cancer. 2021 Feb 13;154:51-61. doi: 10.1016/j.lungcan.2021.02.005. Online ahead of print. PMID: 33611226 Woche 6 (08.02.-14.02.)

Multiple breath washout (MBW) testing using sulfur hexafluoride: reference values and influence of anthropometric parameters.  Trinkmann F, Maros M, Roth K, Hermanns A, Schäfer J, Gawlitza J, Saur J, Akin I, Borggrefe M, Herth FJF, Ganslandt T. Thorax. 2021 Feb 16:thoraxjnl-2020-214717. doi: 10.1136/thoraxjnl-2020-214717. Online ahead of print. PMID: 33593931

Targeting rare and non-canonical driver variants in NSCLC - An uncharted clinical field. Volckmar AL, Christopoulos P, Kirchner M, Allgäuer M, Neumann O, Budczies J, Rempel E, Horak P, Glade J, Goldschmid H, Seker-Cin H, Brandt R, Kriegsmann M, Leichsenring J, Winter H, Faehling M, Fischer JR, Heußel CP, Herth F, Brummer T, Fröhling S, Schirmacher P, Thomas M, Endris V, Penzel R, Kazdal D, Bochtler T, Stenzinger A. Lung Cancer. 2021 Feb 19;154:131-141. doi: 10.1016/j.lungcan.2021.02.022. Online ahead of print. PMID: 33667718

Clinical results of fibroblast activation protein (FAP) specific PET for non-malignant indications: systematic review. Windisch P, Zwahlen DR, Giesel FL, Scholz E, Lugenbiel P, Debus J, Haberkorn U, Adeberg S. EJNMMI Res. 2021 Feb 19;11(1):18. doi: 10.1186/s13550-021-00761-2.PMID: 33606104 Review.

Woche 6 (08.02.-14.02.)

Lorlatinib in pretreated ALK- or ROS1-positive lung cancer and impact of TP53 co-mutations: results from the German early access program. Frost N, Christopoulos P, Kauffmann-Guerrero D, Stratmann J, Riedel R, Schaefer M, Alt J, Gütz S, Christoph DC, Laack E, Faehling M, Fischer R, Fenchel K, Haen S, Heukamp L, Schulz C, Griesinger F. Ther Adv Med Oncol. 2021 Feb 9;13:1758835920980558. doi: 10.1177/1758835920980558. eCollection 2021. PMID: 33613692 Free PMC article.

[Mortality of lung cancer]. Herth F, Nitschmann S. Internist (Berl). 2021 Feb 10. doi: 10.1007/s00108-021-00968-4. Online ahead of print. PMID: 33569696 German. No abstract available.

KRAS G12C-mutated advanced non-small cell lung cancer: A real-world cohort from the German prospective, observational, nation-wide CRISP Registry (AIO-TRK-0315). Sebastian M, Eberhardt WEE, Hoffknecht P, Metzenmacher M, Wehler T, Kokowski K, Alt J, Schütte W, Büttner R, Heukamp LC, Stenzinger A, Jänicke M, Fleitz A, Zacharias S, Dille S, Hipper A, Sandberg M, Weichert W, Groschek M, von der Heyde E, Rauh J, Dechow T, Thomas M, Griesinger F; CRISP Registry Group. Lung Cancer. 2021 Feb 13;154:51-61. doi:10.1016/j.lungcan.2021.02.005. Online ahead of print. PMID: 33611226

Pulmonary hypertension in patients with chronic obstructive lung disease: results from COMPERA. Vizza CD, Hoeper MM, Huscher D, Pittrow D, Benjamin N, Olsson KM, Ghofrani HA, Held M, Klose H, Lange T, Rosenkranz S, Dumitrescu D, Badagliacca R, Claussen M, Halank M, Vonk-Noordegraaf A, Skowasch D, Ewert R, Gibbs JSR, Delcroix M, Skride A, Coghlan G, Ulrich S, Opitz C, Kaemmerer H, Distler O, Grünig E. Chest. 2021 Feb 10:S0012-3692(21)00272-5. doi: 10.1016/j.chest.2021.02.012. Online ahead of print. PMID: 33581097

Woche 5 (01.02.-07.02.)

Prognostic Value of Oxygenated Hemoglobin Assessed during Acute Exacerbations of Chronic Pulmonary Disease. Hinke CF, Jörres RA, Alter P, Bals R, Bornitz F, Kreuter M, Herth FJF, Kahnert K, Kellerer C, Watz H, Budweiser S, Trudzinski FC. Respiration. 2021 Feb 5:1-8. doi: 10.1159/000513440. Online ahead of print. PMID: 33550305

Intracardial PMMA bone cement embolism after kyphoplasty-an unusual cause for sudden chest pain, hemothorax and hemopericardium.  Mathy RM, Kuhn TC, Kappes J, Wielpütz MO, Ruhparwar A, Frankenstein L, Tanner M, Geis N, Fischer C, Kasperk C, Heussel CP, Kreuter M, Wilkens FM. Med Klin Intensivmed Notfmed. 2021 Feb;116(1):61-64. doi: 10.1007/s00063-020-00698-9. Epub 2020 Jun 30. PMID: 32607594 English. No abstract available.

Pseudomonas aeruginosa Modulates the Antiviral Response of Bronchial Epithelial Cells. Sörensen M, Kantorek J, Byrnes L, Boutin S, Mall MA, Lasitschka F, Zabeck H, Nguyen D, Dalpke AH. Front Immunol. 2020 Feb 4;11:96. doi: 10.3389/fimmu.2020.00096. eCollection 2020. PMID: 32117250 Free PMC article.

Quality of Life Three and Twelve Months after Acute Pulmonary Embolism: Analysis from a Prospective Multicenter Cohort Study. Valerio L, Barco S, Jankowski M, Rosenkranz S, Lankeit M, Held M, Gerhardt F, Bruch L, Ewert R, Faehling M, Freise J, Ghofrani HA, Grünig E, Halank M, Hoeper MM, Klok FA, Leuchte HH, Mayer E, Meyer FJ, Neurohr C, Opitz C, Schmidt KH, Seyfarth HJ, Trudzinski F, Wachter R, Wilkens H, Wild PS, Konstantinides SV. Chest. 2021 Feb 3:S0012-3692(21)00242-7. doi: 10.1016/j.chest.2021.01.071. Online ahead of print. PMID: 33548221

Woche 4 (25.01.-31.01.)

Lung cancer patients' comorbidities and attendance of German ambulatory physicians in a 5-year cross-sectional study. Bossert J, Ludwig M, Wronski P, Koetsenruijter J, Krug K, Villalobos M, Jacob J, Walker J, Thomas M, Wensing M. NPJ Prim Care Respir Med. 2021 Jan 28;31(1):2. doi: 10.1038/s41533-020-00214-8. PMID: 33510177

Can autoantibody tests enhance lung cancer screening? - an evaluation of EarlyCDT®-Lung in context of the German Lung Cancer Screening Intervention Trial (LUSI). González Maldonado S, Johnson T, Motsch E, Delorme S, Kaaks R. Transl Lung Cancer Res. 2021 Jan;10(1):233-242. doi: 10.21037/tlcr-20-727. PMID: 33569307 Free PMC article.

Lung cancer prediction by Deep Learning to identify benign lung nodules. Heuvelmans MA, van Ooijen PMA, Ather S, Silva CF, Han D, Heussel CP, Hickes W, Kauczor HU, Novotny P, Peschl H, Rook M, Rubtsov R, von Stackelberg O, Tsakok MT, Arteta C, Declerck J, Kadir T, Pickup L, Gleeson F, Oudkerk M. Lung Cancer. 2021 Jan 31;154:1-4. doi: 10.1016/j.lungcan.2021.01.027. Online ahead of print. PMID: 33556604

nab-Paclitaxel/Carboplatin in Vulnerable Populations With Advanced Non-Small Cell Lung Cancer: Pooled Analysis. Langer CJ, Gajra A, Gridelli C, Konduri K, Morgensztern D, Spigel D, Talbot D, Thomas M, Weiss J, Pilot R, Bhore R, Wolfsteiner M, Ong TJ, Socinski M. Front Oncol. 2021 Jan 26;10:485587. doi: 10.3389/fonc.2020.485587. eCollection 2020. PMID: 33575203 Free PMC article.

Strength in numbers: predicting response to checkpoint inhibitors from large clinical datasets. Stenzinger A, Kazdal D, Peters S. Cell. 2021 Jan 21:S0092-8674(21)00008-8. doi: 10.1016/j.cell.2021.01.008. Online ahead of print. PMID: 33508231

The DIAMORFOSIS (DIAgnosis and Management Of lung canceR and FibrOSIS) survey: international survey and call for consensus. Tzouvelekis A, Antoniou K, Kreuter M, Evison M, Blum TG, Poletti V, Grigoriu B, Vancheri C, Spagnolo P, Karampitsakos T, Bonella F, Wells A, Raghu G, Molina-Molina M, Culver DA, Bendstrup E, Mogulkoc N, Elia S, Cadranel J, Bouros D. ERJ Open Res. 2021 Jan 25;7(1):00529-2020. doi: 10.1183/23120541.00529-2020. eCollection 2021 Jan. PMID: 33532484 Free PMC article.

Woche 3 (18.01.-24.01.)

S2K Guideline for Diagnosis of Idiopathic Pulmonary Fibrosis. Behr J, Günther A, Bonella F, Dinkel J, Fink L, Geiser T, Geissler K, Gläser S, Handzhiev S, Jonigk D, Koschel D, Kreuter M, Leuschner G, Markart P, Prasse A, Schönfeld N, Schupp JC, Sitter H, Müller-Quernheim J, Costabel U. Respiration. 2021 Jan 22:1-34. doi: 10.1159/000512315. Online ahead of print. PMID: 33486500

Neoadjuvant anti-programmed death-1 immunotherapy by pembrolizumab in resectable non-small cell lung cancer: First clinical experience. Eichhorn F, Klotz LV, Kriegsmann M, Bischoff H, Schneider MA, Muley T, Kriegsmann K, Haberkorn U, Heussel CP, Savai R, Zoernig I, Jaeger D, Thomas M, Hoffmann H, Winter H, Eichhorn ME. Lung Cancer. 2021 Jan 21;153:150-157. doi: 10.1016/j.lungcan.2021.01.018. Online ahead of print. PMID: 33529989

Therapeutic Sequencing in ALK+ NSCLC. Elsayed M, Christopoulos P. Pharmaceuticals (Basel). 2021 Jan 21;14(2):80. doi: 10.3390/ph14020080. PMID: 33494549 Review.

A multicentric quality-control study of exercise Doppler echocardiography of the right heart and the pulmonary circulation. The RIGHT Heart International NETwork (RIGHT-NET). Ferrara F, Gargani L, Contaldi C, Agoston G, Argiento P, Armstrong WF, Bandera F, Cademartiri F, Citro R, Cittadini A, Cocchia R, D'Alto M, D'Andrea A, Douschan P, Ghio S, Grünig E, Guazzi M, Guida S, Kasprzak JD, Kolias TJ, Limongelli G, Marra AM, Mazzola M, Mauro C, Moreo A, Pieri F, Pratali L, Pugliese NR, Raciti M, Ranieri B, Rudski L, Saggar R, Salzano A, Serra W, Stanziola AA, Vannan M, Voilliot D, Vriz O, Wierzbowska-Drabik K, Naeije R, Bossone E; RIGHT Heart International NETwork (RIGHT-NET) Investigators. Cardiovasc Ultrasound. 2021 Jan 20;19(1):9. doi: 10.1186/s12947-021-00238-1. PMID: 33472662 Free PMC article.

Deterioration and Mortality Risk of COPD Patients Not Fitting into Standard GOLD Categories: Results of the COSYCONET Cohort. Mayerhofer B, Jörres RA, Lutter JI, Waschki B, Kauffmann-Guerrero D, Alter P, Trudzinski FC, Herth FJF, Holle R, Behr J, Bals R, Welte T, Watz H, Vogelmeier CF, Kahnert K. Respiration. 2021 Jan 22:1-10. doi: 10.1159/000513010. Online ahead of print. PMID: 33486499

Residual symptoms and lower lung function in patients recovering from SARS-CoV-2 infection. Trinkmann F, Müller M, Reif A, Kahn N, Kreuter M, Trudzinski F, Eichinger M, Heussel CP, Herth FJF; Lung Network Rhine-Neckar-Region. Eur Respir J. 2021 Jan 21:2003002. doi: 10.1183/13993003.03002-2020. Online ahead of print. PMID: 33479105 No abstract available.

Woche 2 (11.01.-17.01.)

A gene expression signature associated with B cells predicts benefit from immune checkpoint blockade in lung adenocarcinoma. Budczies J, Kirchner M, Kluck K, Kazdal D, Glade J, Allgäuer M, Kriegsmann M, Heußel CP, Herth FJ, Winter H, Meister M, Muley T, Fröhling S, Peters S, Seliger B, Schirmacher P, Thomas M, Christopoulos P, Stenzinger A. Oncoimmunology. 2021 Jan 11;10(1):1860586. doi: 10.1080/2162402X.2020.1860586. PMID: 33520406 Free PMC article.

How to handle oligometastatic disease in nonsmall cell lung cancer. Eichhorn F, Winter H.Eur Respir Rev. 2021 Jan 13;30(159):200234. doi: 10.1183/16000617.0234-2020. Print 2021 Mar 31. PMID: 33650527

Balanced steady-state free precession MRCP is a robust alternative to respiration-navigated 3D turbo-spin-echo MRCP. Hasse FC, Selmi B, Albusaidi H, Mokry T, Mayer P, Rupp C, Kauczor HU, Weber TF. BMC Med Imaging. 2021 Jan 11;21(1):10. doi: 10.1186/s12880-020-00532-w. PMID: 33430780 Free PMC article.

Monocyte Count as a Prognostic Biomarker in Patients with Idiopathic Pulmonary Fibrosis. Kreuter M, Lee JS, Tzouvelekis A, Oldham JM, Molyneaux PL, Weycker D, Atwood M, Kirchgaessler KU, Maher TM. Am J Respir Crit Care Med. 2021 Jan 12. doi: 10.1164/rccm.202003-0669OC. Online ahead of print. PMID: 33434107 PMID: 33434111

Mild Attenuation of the Pulmonary Inflammatory Response in a Mouse Model of Hereditary Hemochromatosis Type 4. Marques O, Neves J, Horvat NK, Altamura S, Muckenthaler MU. Front Physiol. 2021 Jan 13;11:589351. doi: 10.3389/fphys.2020.589351. eCollection 2020. PMID: 33519502 Free PMC article.

Chest CT Diagnosis and Clinical Management of Drug-related Pneumonitis in Patients Receiving Molecular Targeting Agents and Immune Checkpoint Inhibitors: A Position Paper from the Fleischner Society. Johkoh T, Lee KS, Nishino M, Travis WD, Ryu JH, Lee HY, Ryerson CJ, Franquet T, Bankier AA, Brown KK, Goo JM, Kauczor HU, Lynch DA, Nicholson AG, Richeldi L, Schaefer-Prokop CM, Verschakelen J, Raoof S, Rubin GD, Powell C, Inoue Y, Hatabu H. Radiology. 2021 Jan 12:203427. doi: 10.1148/radiol.2021203427. Online ahead of print.

Iron deficiency. Pasricha SR, Tye-Din J, Muckenthaler MU, Swinkels DW. Lancet. 2021 Jan 16;397(10270):233-248. doi: 10.1016/S0140-6736(20)32594-0. Epub 2020 Dec 4. PMID: 33285139 Review

Accurate and efficient detection of gene fusions from RNA sequencing data. Uhrig S, Ellermann J, Walther T, Burkhardt P, Fröhlich M, Hutter B, Toprak UH, Neumann O, Stenzinger A, Scholl C, Fröhling S, Brors B. Genome Res. 2021 Mar;31(3):448-460. doi: 10.1101/gr.257246.119. Epub 2021 Jan 13. PMID: 33441414 Free PMC article.

Woche 1 (04.01.-10.01.)

Interferon Regulatory Factor 9 Promotes Lung Cancer Progression via Regulation of Versican. Brunn D, Turkowski K, Günther S, Weigert A, Muley T, Kriegsmann M, Winter H, Dammann RH, Stathopoulos GT, Thomas M, Guenther A, Grimminger F, Pullamsetti SS, Seeger W, Savai R. Cancers (Basel). 2021 Jan 8;13(2):E208. doi: 10.3390/cancers13020208. PMID: 33430083

Relationship between airway dysbiosis, inflammation and lung function in adults with cystic fibrosis. Frey DL, Boutin S, Dittrich SA, Graeber SY, Stahl M, Wege S, Herth FJF, Sommerburg O, Schultz C, Mall MA, Dalpke AH. J Cyst Fibros. 2021 Jan 8:S1569-1993(20)30954-1. doi: 10.1016/j.jcf.2020.12.022. Online ahead of print. PMID: 33431308

Suggestions for improving clinical utility of future guidelines for diagnosis and management of IPF - results of a Delphi survey. Funke-Chambour M, Albera C, Bendstrup E, Costabel U, Grutters JC, Harari S, Johannson KA, Kreuter M, Strambu I, Vancheri C, Varone F, Vitulo P, Wuyts WA, Martinez F, Raghu G; Erice participants. Eur Respir J. 2021 Jan 8:2004219. doi: 10.1183/13993003.04219-2020. Online ahead of print. PMID: 33419886 No abstract available.

Joint Statement of the German Respiratory Society and German Society of Thoracic Surgery in Cooperation with the German Radiological Society: Structural Prerequisites of Centres for Interventional Treatment of Emphysema. Gesierich WJ, Darwiche K, Döllinger F, Eberhardt R, Eisenmann S, Grah C, Heußel CP, Huebner RH, Ley-Zaporozhan J, Stanzel F, Welter S, Hoffmann H. Respiration. 2021 Jan 7:1-7. doi: 10.1159/000511599. Online ahead of print. PMID: 33412545

Chest CT Diagnosis and Clinical Management of Drug-related Pneumonitis in Patients Receiving Molecular Targeting Agents and Immune Checkpoint Inhibitors: A Position Paper from the Fleischner Society. Johkoh T, Lee KS, Nishino M, Travis WD, Ryu JH, Lee HY, Ryerson CJ, Franquet T, Bankier AA, Brown KK, Goo JM, Kauczor HU, Lynch DA, Nicholson AG, Richeldi L, Schaefer-Prokop CM, Verschakelen J, Raoof S, Rubin GD, Powell C, Inoue Y, Hatabu H. Chest. 2021 Jan 9:S0012-3692(20)35313-7. doi: 10.1016/j.chest.2020.11.027. Online ahead of print. PMID: 33450293

Acute pulmonary embolism multimodality imaging prior to endovascular therapy. Sin D, McLennan G, Rengier F, Haddadin I, Heresi GA, Bartholomew JR, Fink MA, Thompson D, Partovi S. Int J Cardiovasc Imaging. 2021 Jan;37(1):343-358. doi: 10.1007/s10554-020-01980-9. Epub 2020 Aug 30. PMID: 32862293 Free PMC article. Review.

(01.01.-03.01.)

Predictors and Prognostic Implications of Cardiac Arrhythmias in Patients Hospitalized for COVID-19. Zylla MM, Merle U, Vey JA, Korosoglou G, Hofmann E, Müller M, Herth F, Schmidt W, Blessing E, Göggelmann C, Weidner N, Fiedler MO, Weigand MA, Kälble F, Morath C, Leiner J, Kieser M, Katus HA, Thomas D. J Clin Med. 2021 Jan 2;10(1):133. doi: 10.3390/jcm10010133. PMID: 33401735 Free PMC article.