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© TLRC/Philip Benjamin (Freelance Photographer)

Diese Woche Neu TLRC Fakultät 2024

 

Woche 8 (19.02 - 25.02)

miR-147b mediated suppression of DUSP8 promotes lung cancer progression. Turkowski K, Herzberg F, Günther S, Weigert A, Haselbauer T, Fink L, Brunn D, Grimminger F, Seeger W, Sültmann H, Stiewe T, Pullamsetti SS, Savai R. Oncogene. 2024 Feb 23. doi: 10.1038/s41388-024-02969-7. Online ahead of print.

Advances in the Treatment of Pulmonary Nodules. Zhang Q, Wu X, Yang H, Luo P, Wei N, Wang S, Zhao X, Wang Z, Herth FJF, Zhang X. Respiration. 2024 Feb 21:1-12. doi: 10.1159/000535824. Online ahead of print.

[Tracheal Tumours]. Eichhorn F, Hoffmann H, Rieken S, Herth FJF, Winter H. Zentralbl Chir. 2024 Feb 21. doi: 10.1055/a-2223-1175. Online ahead of print.

[Modern individualized diagnostics and treatment of non-small cell lung cancer]. Winter H, Eichhorn M, Eichhorn F, Grott M. Chirurgie (Heidelb). 2024 Feb 20. doi: 10.1007/s00104-024-02037-6. Online ahead of print.


Woche 7 (12.02 - 18.02)

Phenotyping of COPD with MRI in comparison to same-day CT in a multi-centre trial. Nauck S, Pohl M, Jobst BJ, Melzig C, Meredig H, Weinheimer O, Triphan S, von Stackelberg O, Konietzke P, Kauczor HU, Heußel CP, Wielpütz MO, Biederer J; COSYCONET Study Group. Eur Radiol. 2024 Feb 12. doi: 10.1007/s00330-024-10610-0. Online ahead of print.

[CF Lung Disease - a German S3 Guideline: Pseudomonas aeruginosa]. Schwarz C, Bend J, Hebestreit H, Hogardt M, Hügel C, Illing S, Mainz JG, Rietschel E, Schmidt S, Schulte-Hubbert B, Sitter H, Wielpütz MO, Hammermann J, Baumann I, Brunsmann F, Dieninghoff D, Eber E, Ellemunter H, Eschenhagen P, Evers C, Gruber S, Koitschev A, Ley-Zaporozhan J, Düesberg U, Mentzel HJ, Nüßlein T, Ringshausen FC, Sedlacek L, Smaczny C, Sommerburg O, Sutharsan S, Vonberg RP, Weber AK, Zerlik J. Pneumologie. 2024 Feb 13. doi: 10.1055/a-2182-1907. Online ahead of print.

[Chronic rhinosinusitis in people with cystic fibrosis-an up-to-date review from the perspective of otorhinolaryngology]. Yılmaz Topçuoğlu M, Sommerburg O, Wielpütz MO, Wucherpfennig L, Hackenberg S, Mainz JG, Baumann I. HNO. 2024 Feb 16. doi: 10.1007/s00106-024-01428-9. Online ahead of print.

Analysis of body composition with bioelectrical impedance analysis in patients with severe COPD and pulmonary emphysema. Rott C, Limen E, Kriegsmann K, Herth F, Brock JM. Respir Med. 2024 Feb 11;223:107559. doi: 10.1016/j.rmed.2024.107559. Online ahead of print.

Mediastinal Cryobiopsy for Pathological Diagnosis of Fibrosing Mediastinitis-Associated Pulmonary Hypertension. You YT, Zuo H, Li JM, Zhu XB, Zhang J, Fu WL, Huang ZS, Herth FJ, Fan Y. Respiration. 2024;103(2):95-99. doi: 10.1159/000535395. Epub 2024 Jan 25.

 


Woche 6 (5.02 - 11.02)

Mechanisms controlling cellular and systemic iron homeostasis. Galy B, Conrad M, Muckenthaler M. Nat Rev Mol Cell Biol. 2024 Feb;25(2):133-155. doi: 10.1038/s41580-023-00648-1. Epub 2023 Oct 2.

Robotic-assisted bronchoscopy for the diagnosis of peripheral pulmonary lesions: A systematic review and meta-analysis. Zhang C, Xie F, Li R, Cui N, Herth FJF, Sun J. Thorac Cancer. 2024 Jan 29. doi: 10.1111/1759-7714.15229. Online ahead of print.

Phenotypes and treatment outcomes in idiopathic pulmonary arterial hypertension patients with comorbidities. Skowasch D, Klose H, Ewert R, Wilkens H, Richter M, Rosenkranz S, Setzer G, Grünig E, Halank M. ERJ Open Res. 2024 Jan 29;10(1):00668-2023. doi: 10.1183/23120541.00668-2023. eCollection 2024 Jan.

miR-Blood - a small RNA atlas of human blood components. Jehn J, Trudzinski F, Horos R, Schenz J, Uhle F, Weigand MA, Frank M, Kahraman M, Heuvelman M, Sikosek T, Rajakumar T, Gerwing J, Skottke J, Daniel-Moreno A, Rudolf C, Hinkfoth F, Tikk K, Christopoulos P, Klotz LV, Winter H, Kreuter M, Steinkraus BR. Sci Data. 2024 Feb 2;11(1):164. doi: 10.1038/s41597-024-02976-z.

Genomic heterogeneity at baseline is associated with T790M resistance mutations in EGFR-mutated lung cancer treated with the first-/second-generation tyrosine kinase inhibitors. Menzel M, Kirchner M, Kluck K, Ball M, Beck S, Allgäuer M, Assmann C, Schnorbach J, Volckmar AL, Tay TKY, Goldschmid H, Tan DS, Thomas M, Kazdal D, Budczies J, Stenzinger A, Christopoulos P. J Pathol Clin Res. 2024 Mar;10(2):e354. doi: 10.1002/cjp2.354.

Role of multidrug-resistant bacteria in weaning from invasive mechanical ventilation. Michels-Zetsche JD, Gassmann V, Jasuja JK, Neetz B, Höger P, Meis J, Britsch S, Sommerwerck U, Fähndrich S, Bornitz F, Müller MM, Herth FJF, Trudzinski FC. Respir Res. 2024 Feb 5;25(1):69. doi: 10.1186/s12931-024-02694-5.

Patient-reported outcomes in advanced NSCLC before and during the COVID-19 pandemic: Real-world data from the German prospective CRISP Registry (AIO-TRK-0315). Sebastian M, Eberhardt WEE, von der Heyde E, Dörfel S, Wiegand J, Schiefer C, Losem C, Jänicke M, Fleitz A, Zacharias S, Kaiser-Osterhues A, Hipper A, Dietel C, Bleckmann A, Benkelmann R, Boesche M, Grah C, Müller A, Griesinger F, Thomas M; CRISP Registry Group. Int J Cancer. 2024 Feb 8. doi: 10.1002/ijc.34868. Online ahead of print.

Oral Treprostinil is Associated with Improved Survival in FREEDOM-EV and its Open-Label Extension. Grünig E, Rahaghi F, Elwing J, Vizza CD, Pepke-Zaba J, Shen J, Yao H, Hage A, Rosenkranz S, Vonk M, Balasubramanian V, Yuanhua Y, Yu Z, Lordan J, Cadaret L, Grover R, Ousmanou A, Seaman S, Deng C, Broderick M, White RJ; FREEDOM-EV Investigators. Adv Ther. 2024 Feb;41(2):618-637. doi: 10.1007/s12325-023-02711-x. Epub 2023 Dec 6.


Woche 5 (29.01 - 04.02)

Utility of rehabilitation prior to bronchoscopic lung volume reduction: post hoc analysis of the VENT trial. Brock JM, Kontogianni K, Sciurba FC, Criner GJ, Herth F. ERJ Open Res. 2024 Jan 22;10(1):00735-2023. doi: 10.1183/23120541.00735-2023. eCollection 2024 Jan. 

First-line immunotherapy for lung cancer with MET exon 14 skipping and the relevance of TP53 mutations. Blasi M, Kuon J, Lüders H, Misch D, Kauffmann-Guerrero D, Hilbrandt M, Kazdal D, Falkenstern-Ge RF, Hackanson B, Dintner S, Faehling M, Kirchner M, Volckmar AL, Kopp HG, Allgäuer M, Grohé C, Tufman A, Reck M, Frost N, Stenzinger A, Thomas M, Christopoulos P. Eur J Cancer. 2024 Jan 17;199:113556. doi: 10.1016/j.ejca.2024.113556. Online ahead of print. 

Echo time-dependent observed T1 and quantitative perfusion in chronic obstructive pulmonary disease using magnetic resonance imaging. Triphan SMF, Konietzke M, Biederer J, Eichinger M, Vogelmeier CF, Jörres RA, Kauczor HU, Heußel CP, Jobst BJ, Wielpütz MO; COSYCONET study group. Front Med (Lausanne). 2024 Jan 5;10:1254003. doi: 10.3389/fmed.2023.1254003. eCollection 2023. 

Influence of Season, Storage Temperature and Time of Sample Collection in Pancreatitis-Associated Protein-Based Algorithms for Newborn Screening for Cystic Fibrosis. Maier P, Jeyaweerasinkam S, Eberhard J, Soueidan L, Hämmerling S, Kohlmüller D, Feyh P, Gramer G, Garbade SF, Hoffmann GF, Okun JG, Sommerburg O. Int J Neonatal Screen. 2024 Jan 12;10(1):5. doi: 10.3390/ijns10010005.

Randomized Trial of Macitentan/Tadalafil Single-Tablet Combination Therapy for Pulmonary Arterial Hypertension. Grünig E, Jansa P, Fan F, Hauser JA, Pannaux M, Morganti A, Rofael H, Chin KM. J Am Coll Cardiol. 2024 Jan 30;83(4):473-484. doi: 10.1016/j.jacc.2023.10.045. 

Risk factors for long-term invasive mechanical ventilation: a longitudinal study using German health claims data. Trudzinski FC, Michels-Zetsche JD, Neetz B, Meis J, Müller M, Kempa A, Neurohr C, Schneider A, Herth FJF, Szecsenyi J, Biehler E, Fleischauer T, Wensing M, Britsch S, Schubert-Haack J, Grobe T, Frerk T; PRiVENT-study group. Respir Res. 2024 Jan 27;25(1):60. doi: 10.1186/s12931-024-02693-6.

Midregional proatrial naturetic peptide (MRproANP) and copeptin (COPAVP) as predictors of all-cause mortality in recently diagnosed mild to moderate COPD-results from COSYCONET. Fähndrich S, Herr C, Teuteberg S, Alter P, Söhler S, Soriano D, Classen J, Adams J, Weinhold V, Watz H, Waschki B, Zeller T, Eichenlaub M, Trudzinski FC, Michels JD, Omlor A, Seiler F, Moneke I, Biertz F, Stolz D, Welte T, Kauczor HU, Kahnert K, Jörres RA, Vogelmeier CF, Bals R; German COSYCONET Cohort. Respir Res. 2024 Jan 24;25(1):56. doi: 10.1186/s12931-024-02690-9.


Woche 3 (15.01 - 21.01)

Sfrp1 inhibits lung fibroblast invasion during transition to injury induced myofibroblasts. Mayr CH, Sengupta A, Asgharpour S, Ansari M, Pestoni JC, Ogar P, Angelidis I, Liontos A, Rodriguez-Castillo JA, Lang NJ, Strunz M, Porras-Gonzalez D, Gerckens M, De Sadeleer LJ, Oehrle B, Viteri-Alvarez V, Fernandez IE, Tallquist M, Irmler M, Beckers J, Eickelberg O, Stoleriu GM, Behr J, Kneidinger N, Wuyts WA, Wasnick RM, Yildirim AÖ, Ahlbrecht K, Morty RE, Samakovlis C, Theis FJ, Burgstaller G, Schiller HB. Eur Respir J. 2024 Jan 11:2301326. doi: 10.1183/13993003.01326-2023. Online ahead of print.

Alveolar macrophage-expressed Plet1 is a driver of lung epithelial repair after viral pneumonia. Pervizaj-Oruqaj L, Selvakumar B, Ferrero MR, Heiner M, Malainou C, Glaser RD, Wilhelm J, Bartkuhn M, Weiss A, Alexopoulos I, Witte B, Gattenlöhner S, Vadász I, Morty RE, Seeger W, Schermuly RT, Vazquez-Armendariz AI, Herold S. Nat Commun. 2024 Jan 2;15(1):87. doi: 10.1038/s41467-023-44421-6. 

Alpha-1-antitrypsin-deficiency is associated with lower cardiovascular risk: an approach based on federated learning. Zöller D, Haverkamp C, Makoudjou A, Sofack G, Kiefer S, Gebele D, Pfaffenlehner M, Boeker M, Binder H, Karki K, Seidemann C, Schmeck B, Greulich T, Renz H, Schild S, Seuchter SA, Tibyampansha D, Buhl R, Rohde G, Trudzinski FC, Bals R, Janciauskiene S, Stolz D, Fähndrich S. Respir Res. 2024 Jan 18;25(1):38. doi: 10.1186/s12931-023-02607-y.

Hospitalisation patterns in interstitial lung diseases: data from the EXCITING-ILD registry.  Buschulte K, Kabitz HJ, Hagmeyer L, Hammerl P, Esselmann A, Wiederhold C, Skowasch D, Stolpe C, Joest M, Veitshans S, Höffgen M, Maqhuzu P, Schwarzkopf L, Hellmann A, Pfeifer M, Behr J, Karpavicius R, Günther A, Polke M, Höger P, Somogyi V, Lederer C, Markart P, Kreuter M. Respir Res. 2024 Jan 4;25(1):5. doi: 10.1186/s12931-023-02588-y.

Elexacaftor/tezacaftor/ivacaftor improves chronic rhinosinusitis detected by magnetic resonance imaging in children with cystic fibrosis on long-term therapy with lumacaftor/ivacaftor. Wucherpfennig L, Becker JKZ, Wuennemann F, Eichinger M, Seitz A, Baumann I, Stahl M, Graeber SY, Zhao S, Chung J, Schenk JP, Alrajab A, Kauczor HU, Mall MA, Sommerburg O, Wielpütz MO. J Cyst Fibros. 2024 Jan 12:S1569-1993(24)00004-3. doi: 10.1016/j.jcf.2024.01.004. Online ahead of print.

Therapeutic drug monitoring of osimertinib in non-small cell lung cancer and short bowel syndrome: A case report. Longuespée R, Kunz J, Fresnais M, Foerster KI, Burhenne J, Thomas M, Kazdal D, Stenzinger A, Christopoulos P, Haefeli WE. Br J Clin Pharmacol. 2024 Jan;90(1):344-349. doi: 10.1111/bcp.15924.

Mask Continuous Positive Airway Pressure Increases Diaphragm Thickening Fraction in Healthy Subjects. Lindner S, Teichert J, Hoermann C, Michels JD, Herth FJF, Duerschmied D, Britsch S. Respiration. 2024 Jan 16:1-5. doi: 10.1159/000535990. Online ahead of print.


Woche 2 (8.01 - 14.01)

MRI of Pulmonary and Paranasal Sinus Abnormalities in Children with Primary Ciliary Dyskinesia Compared to Children with Cystic Fibrosis.  Wucherpfennig L, Wuennemann F, Eichinger M, Schmitt N, Seitz A, Baumann I, Roehmel JF, Stahl M, Hämmerling S, Chung J, Schenk JP, Alrajab A, Kauczor HU, Mall MA, Wielpütz MO, Sommerburg O. Ann Am Thorac Soc. 2024 Jan 11. doi: 10.1513/AnnalsATS.202305-453OC. Online ahead of print.

Characterization of transient and progressive pulmonary fibrosis by spatially correlated phase contrast microCT, classical histopathology and atomic force microscopy.  D'Amico L, Svetlove A, Longo E, Meyer R, Senigagliesi B, Saccomano G, Nolte P, Wagner WL, Wielpütz MO, Leitz DHW, Duerr J, Mall MA, Casalis L, Köster S, Alves F, Tromba G, Dullin C. Comput Biol Med. 2024 Jan 8;169:107947. doi: 10.1016/j.compbiomed.2024.107947.

Nasal lavage microbiome, but not nasal swab microbiome, correlates with sinonasal inflammation in children with cystic fibrosis.  Chung J, Boutin S, Frey DL, Joachim C, Mall MA, Sommerburg O. J Cyst Fibros. 2024 Jan 9:S1569-1993(23)01735-6. doi: 10.1016/j.jcf.2023.12.011. Online ahead of print.


Woche 1 (01.01 - 07.01)

Clinical effectiveness of robotic-assisted compared to open or video-assisted lobectomy in Germany: a real-world data analysis. Eichhorn M, Bernauer E, Rotärmel A, Heurich M, Winter H. Interdiscip Cardiovasc Thorac Surg. 2024 Jan 4:ivae001. doi: 10.1093/icvts/ivae001. Online ahead of print.

Comparison of cryobiopsy and forceps biopsy for the diagnosis of mediastinal lesions: A randomised clinical trial.  Cheng TL, Huang ZS, Zhang J, Wang J, Zhao J, Kontogianni K, Fu WL, Wu N, Kuebler WM, Herth FJ, Fan Y. Pulmonology. 2024 Jan 4:S2531-0437(23)00240-4. doi: 10.1016/j.pulmoe.2023.12.002. Online ahead of print.