Diese Woche Neu TLRC Fakultät 2025
Woche 29 (14.07 - 20.07)
Robotic tracheobronchoplasty with vertical suturing for excessive dynamic airway collapse. Campisi A, Winter H, Heussel CP, Eichhorn ME. JTCVS Tech. 2025 Apr 9;31:195-197. doi: 10.1016/j.xjtc.2025.03.024. PMID: 40641781; PMCID: PMC12237877.
Survival Outcomes and Impact of Targeted PAH Therapy in Portopulmonary Hypertension in the PVRI GoDeep Meta-Registry. Jose A, Yogeswaran A, Fuenderich M, Kiely D, Sweatt AJ, Zamanian RT, Hassoun PM, Mouawad A, Balasubramanian A, Wilkins M, Lawrie A, Howard L, Sahay S, Olschewski H, Kovacs G, Saleh K, Sabbour H, Eichstaedt CA, Grünig E, Giannakoulas G, Arvanitaki A, Sirenko Y, Torbas O, Cajigas H, Frantz R, Scelsi L, Ghio S, Majeed RW, Wilhelm J, Ghofrani HA, Grimminger F, Tello K, Elwing J, Seeger W; PVRI‐GoDeep‐Consortium. Pulm Circ. 2025 Jul 8;15(3):e70121. doi: 10.1002/pul2.70121. PMID: 40636151; PMCID: PMC12237829.
Genotype and transcript processing of the tumour necrosis factor receptor TNFRSF1A in epithelial cells: implications for survival in cystic fibrosis. Uden A, Dunsche I, Janciauskiene S, Gräber S, Feng L, Tamm S, Hedtfeld S, Stege G, Jahn K, Kontsendorn J, Alfeis N, Kühbandner I, Minso R, Dopfer C, Griese M, Sommerburg O, Ringshausen FC, Nährlich L, Hansen G, Welte T, Braubach P, Mall MA, Tümmler B, Dittrich AM, Stanke F; CF teams from the European CF Twin and Sibling Study. EBioMedicine. 2025 Jul 10;118:105848. doi: 10.1016/j.ebiom.2025.105848. Epub ahead of print. PMID: 40645008.
Woche 28 (07.07. - 13.07)
Lazertinib Versus Osimertinib in Previously Untreated EGFR-mutant Advanced NSCLC: A Randomized, Double-blind, Exploratory Analysis From MARIPOSA. Lee SH, Lu S, Hayashi H, Felip E, Spira AI, Girard N, Kim YJ, Ostapenko Y, Danchaivijitr P, Liu B, Alip A, Korbenfeld E, Mourão Dias J, Lee KH, Xiong H, How SH, Cheng Y, Chang GC, Yang JC, Besse B, Thomas M, Shah S, Baig M, Curtin JC, Zhang J, Xie J, Sun T, Sethi S, Wang M, Fennema E, Daksh M, Ennis M, Bauml JM, Cho BC. J Thorac Oncol. 2025 Jul 3:S1556-0864(25)00821-4. doi: 10.1016/j.jtho.2025.06.030. Epub ahead of print. PMID: 40617394.
Fluid restriction in patients with pulmonary arterial hypertension and right heart failure. Benjamin N, Resag C, Xanthouli P, Harutyunova S, Eichstaedt C, Egenlauf B, Grünig E. Respiration. 2025 Jul 5:1-25. doi: 10.1159/000546769. Epub ahead of print. PMID: 40618739.
Shape sensing robotic assisted bronchoscopy versus virtual bronchoscopic navigation in the diagnosis of peripheral pulmonary nodules. Zhang Q, Wen F, Wu X, Yang H, Li X, Luo P, Liu H, Wang Z, Herth FJF, Zhang X. Sci Rep. 2025 Jul 4;15(1):23950. doi: 10.1038/s41598-025-08798-2. PMID: 40615493; PMCID: PMC12227645.
Efficacy and Safety of Airway Stent Placement in the Treatment of Airway Esophageal Fistula. Li X, Luo P, Zhao M, Wen F, Jiang G, You Y, Liu Y, Wu X, Herth FJF, Zhang Q. Respiration. 2025;104(7):476-484. doi: 10.1159/000544124. Epub 2025 Feb 17. PMID: 39961291.
Lung cancer screening with low-dose CT: definition of positive, indeterminate, and negative screen results. A nodule management recommendation from the European Society of Thoracic Imaging. Snoeckx A, Silva M, Prosch H, Biederer J, Frauenfelder T, Gleeson F, Jacobs C, Kauczor HU, Parkar AP, Schaefer-Prokop C, Prokop M, Revel MP. Eur Radiol. 2025 Jul 1. doi: 10.1007/s00330-025-11648-4. Epub ahead of print. PMID: 40593170.
Aggressiveness-guided nodule management for lung cancer screening in Europe-justification for follow-up intervals and definition of growth. Prokop M, Schaefer-Prokop C, Jacobs C, Snoeckx A, Biederer J, Frauenfelder T, Gleeson F, Kauczor HU, Parkar AP, Vliegenthart R, Revel MP, Silva M, Prosch H. Eur Radiol. 2025 Jul 1. doi: 10.1007/s00330-025-11647-5. Epub ahead of print. PMID: 40593169.
Woche 27 (30.06. - 06.07)
Robotic-assisted versus open resection of pulmonary sequestration: a retrospective cohort study. RATS surgery for pulmonary sequestration. Deissner H, Campisi A, Griffo R, Niedermaier B, Muley T, Allgäuer M, Winter H, Eichhorn ME. Gen Thorac Cardiovasc Surg. 2025 Jun 24. doi: 10.1007/s11748-025-02172-9. Epub ahead of print. PMID: 40553225.
First European Experience of Shape-Sensing Robotic-assisted bronchoscopy: Learning Curve Analysis. Brock JM, Dittrich AS, Kontogianni K, Heussel CP, Klotz LV, Winter H, Schellenberg M, Herth FJ. Respiration. 2025 Jun 24:1-23. doi: 10.1159/000546591. Epub ahead of print. PMID: 40555225.
World Association for Bronchology and Interventional Pulmonology (WABIP) Guidelines on Airway Stenting for Benign Central Airway Obstruction. Respirology. Chaddha U, Agrawal A, Murgu S, Ghori U, Trias-Sabria P, Ortiz-Comino R, Dutau H, Freitag L, Gasparini S, Lee P, Dooms C, Trisolini R, Madariaga MLL, Li S, Zuccatosta L, Herth F, Saka H, Fielding D, Oki M, Rosell A. 2025 Jul;30(7):587-604. doi: 10.1111/resp.70068. Epub 2025 Jun 27. PMID: 40575842.
Woche 26 (23.06 - 29.06)
Quantitative spectral computed tomography detects different patterns of airway wall thickening and contrast enhancement in infective lung disease: a feasibility study. Konietzke P, Thomä J, Weinheimer O, Do TD, Wagner WL, Bodenberger AL, Stiller W, Weber TF, Heußel CP, Kauczor HU, Wielpütz MO. Eur Radiol. 2025 Jun 19. doi: 10.1007/s00330-025-11752-5. Epub ahead of print. PMID: 40536704.
Impact of omitting clinical target volume in radiotherapy for locally advanced non-small cell lung cancer: a propensity score matching analysis. Liu L, Bao W, Yuan X, Zhu Y, Zhang Y, Christopoulos P, Abbar B, Qian C, Yang S, Xu Y. Transl Lung Cancer Res. 2025 May 30;14(5):1770-1785. doi: 10.21037/tlcr-2025-409. Epub 2025 May 28. PMID: 40535086; PMCID: PMC12170249.
Cancer-associated fibroblasts promote drug resistance in ALK-driven lung adenocarcinoma cells by upregulating lipid biosynthesis. Daum AK, Schlicker L, Schneider MA, Muley T, Klingmüller U, Schulze A, Thomas M, Christopoulos P, Sültmann H. Cancer Metab. 2025 Jun 16;13(1):28. doi: 10.1186/s40170-025-00400-7. PMID: 40524253; PMCID: PMC12168422.
Unmet needs of patients with COPD in Germany: a retrospective, cross-sectional study. Herth FJF, Vogelmeier CF, Trudzinski FC, Watz H, Skowasch D, Beeh KM, Compton C, Mohan T, Richter H, Claussen J, Bartel S. ERJ Open Res. 2025 Jun 16;11(3):00976-2024. doi: 10.1183/23120541.00976-2024. PMID: 40524930; PMCID: PMC12168169.
Identifying Clinical Research Priorities in Interventional Pulmonary: An Interventional Pulmonology Outcomes Group (IPOG) Working Group Report. Thiboutot J, Yarmus LB, Maldonado F, Silvestri G, Vachani A, Wahidi M, Gonzalez A, Argento AC, Lee HJ, Mazzone P, Herth F, Chen A, Akulian J, Lee YCG, Navani N, Kapp C, Feller-Kopman D, Maskell NA, Shah PL, DeMaio A, Liberman M, Gleeson F, Moore AJ, van der Heijden EHFM, Bedawi EO, Beattie J, Rahman NM, Gilbert CR. Ann Am Thorac Soc. 2025 Jun 16. doi: 10.1513/AnnalsATS.202502-242PS. Epub ahead of print. PMID: 40523281.
Functional Characterization of Variants of Unknown Significance of Fibroblast Growth Factor Receptors 1-4 and Comparison With AI Model-Based Prediction. Ziegler M, Khoury N, Hommerich LM, Adler H, Loges S. JCO Precis Oncol. 2025 Jun;9:e2400847. doi: 10.1200/PO-24-00847. Epub 2025 Jun 17. PMID: 40526877.
Woche 25 (16.06 - 22.06)
Image analysis: 68Ga-FAPI-46 PET derived texture parameters improve the differentiation of malignant and benign pulmonary lesions. Wessendorf J, Spektor AM, Aboulmaouahib B, Daum J, Glatting FM, Schlamp K, Grott M, Eichhorn F, Heußel CP, Kauczor HU, Kreuter M, Schreckenberger M, Winter H, Haberkorn U, Röhrich M. Cancer Imaging. 2025 Jun 12;25(1):73. doi: 10.1186/s40644-025-00886-w. PMID: 40506754; PMCID: PMC12164081.
German National Guideline for Treating Chronic Respiratory Failure with Non-Invasive Ventilation. Respiration. Stanzel SB, Spiesshoefer J, Trudzinski FC, Cornelissen CG, Kabitz HJ, Fuchs H, Boentert M, Mathes T, Michalsen A, Hirschfeld S, Dreher M, Windisch W, Walterspacher S. 2025 Jun 13:1-100. doi: 10.1159/000546843. Epub ahead of print. PMID: 40517762.
Woche 24 (09.06. - 15.06.)
Lungenkrebs: Das ist in der hausärztlichen Praxis zu tun [Lung cancer - what general practicioners should know]. Herth FJF. MMW Fortschr Med. 2025 Jun;167(10):46-47. German. doi: 10.1007/s15006-025-4958-8. PMID: 40467810.
Lungenkrebsscreening - eine neue Option zur Früherkennung [Lung cancer screening - a new option for early detection]. Herth FJF. MMW Fortschr Med. 2025 Jun;167(10):48-49. German. doi: 10.1007/s15006-025-4974-8. PMID: 40467811.
Thoracic MRI in pleural infection - a feasibility study from patients' and radiographers' perspectives. Pietersen PI, Jakobsen TS, Harders SMW, Biederer J, Luef SM, Bendixen M, Davidsen JR, Laursen CB. Curr Probl Diagn Radiol. 2025 Jul-Aug;54(4):449-454. doi: 10.1067/j.cpradiol.2024.10.001. Epub 2024 Oct 5. PMID: 39384484.
Corrigendum to "A reproducibility study on invasion in small pulmonary adenocarcinoma according to the WHO and a modified classification, supported by biomarkers" [Lung Cancer 199 (2025) 108060]. Thunnissen E, Blaauwgeers H, Filipello F, Lissenberg-Witte B, Minami Y, Noguchi M, Quesne JL, Papotti MG, Flieder DB, Pelosi G, Sansano I, Berezowska S, Ryška A, Brcic L, Motoi N, Nakatani Y, Kuempers C, Hofman P, Hofman V, Dale VG, Rossi G, Ambrosi F, Matsubara D, Ishikawa Y, Weynand B, Calabrese F, Pezzuto F, Kern I, Nicholson S, Mutka A, Dacic S, Beasley MB, Arrigoni G, Timens W, Ooft ML, Brinkhuis M, Bulkmans N, Britstra R, Vreuls W, Jones KD, von der Thüsen JH, Hager H, Perner S, Moore D, Leonte DG, Janabi SA, Schønau A, Neumann O, Kluck K, Ourailidis I, Ball M, Budczies J, Kazdal D, Stenzinger A. Lung Cancer. 2025 Jun;204:108488. doi: 10.1016/j.lungcan.2025.108488. Epub 2025 Jun 3. Erratum for: Lung Cancer. 2025 Jan;199:108060. doi: 10.1016/j.lungcan.2024.108060. PMID: 40473341.
Woche 23 (02.06. - 08.06)
Influence of age on outcomes in prolonged weaning from mechanical ventilation. Michels-Zetsche JD, Röser E, Ersöz H, Neetz B, Dahlhoff JC, Joves B, Trinkmann F, Höger P, Kontogianni K, Weissmann C, Barre M, Fähndrich S, Bornitz F, Müller MM, Herth F, Trudzinski F. BMJ Open Respir Res. 2025 Jun 1;12(1):e002730. doi: 10.1136/bmjresp-2024-002730. PMID: 40451295.
Interprofessional collaboration and job satisfaction in German intensive care units - a cross-sectional survey within the PRiVENT project. Fleischhauer T, Biehler E, Michels-Zetsche JD, Trudzinski FC, Schubert-Haack J, Forstner J, Schneider A, Kempa A, Joves B, Neurohr C, Herth FJ, Szecsenyi J, Wensing M. Respiration. 2025 May 26:1-18. doi: 10.1159/000546043. Epub ahead of print. PMID: 40418908.
Impact of the number of involved lymph node zones on survival in stage IIIA-N2 lung adeno and squamous cell carcinoma. Griffo R, Hoffmann H, Safi S, Eichhorn F, Klotz LV, Muley T, Baum P, Kriegsmann M, Bischoff H, Winter H, Eichhorn ME. Interdiscip Cardiovasc Thorac Surg. 2025 May 27:ivaf121. doi: 10.1093/icvts/ivaf121. Epub ahead of print. PMID: 40424415.
Persisting CD19.CAR-T cells in combination with nintedanib: clinical response in a patient with systemic sclerosis-associated pulmonary fibrosis after 2 years. Merkt W, Röhrich M, Mavriopoulou E, Stütz AN, Distler JHW, Schmitt A, Polke M, Heußel CP, Schmitt M, Lorenz HM. Lancet Respir Med. 2025 May 28:S2213-2600(25)00159-6. doi: 10.1016/S2213-2600(25)00159-6. Epub ahead of print. PMID: 40449514.
Prognostic value of CT-defined coronary sclerosis in COVID-19: results of a multicenter study based on the Weston score. Bucher AM, Frodl E, Ehrengut C, Müller L, Emrich T, Kloeckner R, Sieren M, Sähn MJ, Fink MA, Móré D, Melekh B, Gottschling S, Meinel F, Schön H, Kornemann N, Renz DM, Lubina N, Wollny C, May MS, Siegler L, Borggrefe J, Meyer HJ, Surov A. Rofo. 2025 May 26. English, German. doi: 10.1055/a-2583-0235. Epub ahead of print. PMID: 40418966.
Integrated 3D imaging of FFPE lung tissue combining microCT, light and electron microscopy allows for contextualized ultrastructural and histological analysis. Reiser J, Albers J, Svetlove A, Mertiny M, Kommoss FKF, Schwab C, Schneemann A, Tromba G, Wacker I, Curticean RE, Schroeder RR, Kauczor HU, Wielpütz MO, Dullin C, Wagner WL. Sci Rep. 2025 May 28;15(1):18656. doi: 10.1038/s41598-025-02770-w. PMID: 40437062; PMCID: PMC12120005.
RNF20 links the DNA damage response and metabolic rewiring in lung cancer through HIF1α. Liu H, Tang Y, Singh A, Vong J, Cordero J, Mathes A, Gao R, Jia Y, Garvalov BK, Acker T, Poschet G, Hell R, Schneider MA, Heineke J, Wieland T, Barreto G, Cerwenka A, Potente M, Bibli SI, Savai R, Dobreva G. Nat Commun. 2025 May 28;16(1):4929. doi: 10.1038/s41467-025-60223-4. PMID: 40436847; PMCID: PMC12120090.
Sotatercept in Patients with Pulmonary Arterial Hypertension at High Risk for Death. Humbert M, McLaughlin VV, Badesch DB, Ghofrani HA, Gibbs JSR, Gomberg-Maitland M, Preston IR, Souza R, Waxman AB, Moles VM, Savale L, Vizza CD, Rosenkranz S, Shi Y, Miller B, Mackenzie HS, Kim SS, Loureiro MJ, Patel MJ, Koglin J, Cornell AG, Hoeper MM; ZENITH Trial Investigators. N Engl J Med. 2025 May 29;392(20):1987-2000. doi: 10.1056/NEJMoa2415160. Epub 2025 Mar 31. PMID: 40167274.
Efficient and multiplexed somatic genome editing with Cas12a mice. Hebert JD, Xu H, Tang YJ, Ruiz PA, Detrick CR, Wang J, Hughes NW, Donosa O, Siah VP, Andrejka L, Karmakar S, Aboiralor I, Tang R, Sotillo R, Sage J, Cong L, Petrov DA, Winslow MM. Nat Biomed Eng. 2025 May 30. doi: 10.1038/s41551-025-01407-7. Epub ahead of print. PMID: 40447760.
Woche 22 (26.05 - 01.06)
Lung MRI: Indications, Capabilities, and Techniques-AJR Expert Panel Narrative Review. Azour L, Ohno Y, Biederer J, Hochhegger B, Bauman G, Hatabu H, Schiebler ML, Ackman JB. AJR Am J Roentgenol. 2025 May 21. doi: 10.2214/AJR.25.32637. Epub ahead of print. PMID: 40397559.
Woche 21 (19.05 - 25.05)
Comment on Akil et al. Nonintubated versus Intubated Lung Volume Reduction Surgery in Patients with End-Stage Lung Emphysema and Hypercapnia. Trudzinski FC, Hoffmann H, Langer F, Kontogianni K, Mahlmann J, Eberhardt R. J. Clin. Med. 2023, 12, 3750. J Clin Med. 2025 Apr 29;14(9):3062. doi: 10.3390/jcm14093062. PMID: 40364099; PMCID: PMC12072609.
S2k-Leitlinie Fachärztliche Diagnostik und Therapie von erwachsenen Patienten mit Husten [Specialist Guidelines of The German Respiratory Society for Diagnosis and Treatment of adult Patients Suffering from Cough]. Kardos P, Becker S, Heidenreich KR, Klimek L, Köhnlein T, Labenz J, Mülleneisen N, Pfeiffer-Kascha D, Pink I, Sitter H, Trinkmann F, Worth H, Winterholler C; Deutsche Gesellschaft für Pneumologie und Beatmungsmedizin e.V. (DGP) (federführende Fachgesellschaft); Ärzteverband Deutscher Allergologen e.V. (AeDA); Bundesverband der Pneumologie, Schlaf- und Beatmungsmedizin e.V. (BdP); DCFH – Deutsche CF-Hilfe Unterstützung für Menschen mit Mukoviszidose e.V.; Deutsche Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten e.V. (DGVS); Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde Kopf- und Hals-Chirurgie e.V. (DGHNO-KHC); Deutsche Gesellschaft für Innere Medizin e.V. (DGIM); Deutscher Bundesverband für Logopädie e.V. (dbl); Deutscher Verband für Physiotherapie e.V. (Physio Deutschland). . Pneumologie. 2025 May;79(5):329-357. German. doi: 10.1055/a-2550-3738. Epub 2025 May 12. PMID: 40354786.
Full-field Brillouin microscopy based on an imaging Fourier-transform spectrometer. Bevilacqua C, Prevedel R. Nat Photonics. 2025;19(5):494-501. doi: 10.1038/s41566-025-01619-y. Epub 2025 Feb 20. PMID: 40352679; PMCID: PMC12058527.
Endovascular management of acute superior mesenteric vein thrombosis: a retrospective study on thrombolysis outcomes. Wei N, Mathy RM, Chang DH, Loos M, Merle U, Gauss A, Boxberger M, Mayer P, Klauss M, Kauczor HU, Öcal O, Wielpütz MO. CVIR Endovasc. 2025 May 14;8(1):41. doi: 10.1186/s42155-025-00558-7. PMID: 40366487; PMCID: PMC12078909.
Coupling Immunoprecipitation with Multiplexed Digital PCR for Cell-Free DNA Methylation Detection in Small Plasma Volumes of Early-Onset Colorectal Cancer. Truong TT, Mikloska K, Sum J, Oberländer M, von Bubnoff N, Christiansen L, Tornow S, Derer S, Janke F, Sültmann H, Zeissig S, Linnebacher M, Schafmayer C, Lehnert M, Hutzenlaub T, Paust N, Juelg P. Anal Chem. 2025 May 16. doi: 10.1021/acs.analchem.5c01361. Epub ahead of print. PMID: 40380352.
Thoracic Oncology Highlights from the European Society for Medical Oncology Annual Meeting 2024: Non-Targeted therapy in Non-Small Cell Lung Cancer, Small Cell Lung Cancer and Thymic Epithelial Tumors. Leßmann ME, Sibbert C, Reitnauer L, Heinzen S, Webendörfer M, Overbeck TR, Griesinger F, Bleckmann A, Wiesweg M, Tufman A, Thomas M, Kropf-Sanchen C. Oncol Res Treat. 2025 Apr 1:1-7. doi: 10.1159/000545493. Epub ahead of print. PMID: 40168951.
Woche 20 (12.05 - 18.05)
Treatment sequences in BRAF-V600-mutated non-small cell lung cancer: First-line targeted therapy versus first-line (chemo-) immunotherapy. Wiesweg M, Alaffas A, Rasokat A, Saalfeld FC, Rost M, Assmann C, Herster F, Hilbrandt M, Griesinger F, Kron A, Roeper J, Glanemann F, Kropf-Sanchen C, Reck M, Kulhavy J, Stenzinger A, Wolf J, Sebastian M, Schuler M, Wermke M, Frost N, Kopp HG, Christopoulos P, Scheffler M. J Thorac Oncol. 2025 May 7:S1556-0864(25)00706-3. doi: 10.1016/j.jtho.2025.04.016. Epub ahead of print. PMID: 40345491.
Herausforderungen und Chancen des Intensivpflege- und Rehabilitationsstärkungsgesetzes (GKV-IPReG): Meinungsbild und interprofessioneller sektorenübergreifender Dialog [Challenges and opportunities of the Intensive Care and Rehabilitation Strengthening Act (GKV-IPReG): Opinion survey and interprofessional cross-sector dialogue]. Dahlhoff JC, Joves B, Neetz B, Iberl G, Heinze A, Sommerwerck U, Geiseler J, Brennauer K, Gaiser F, Westhoff M, Michels J, Barre M, Herth F, Trudzinski F. Pneumologie. 2025 May 9. German. doi: 10.1055/a-2592-0331. Epub ahead of print. PMID: 40345234.
Air artifact suppression in phase contrast micro-CT using conditional generative adversarial networks. Sagar MMR, D'Amico L, Longo E, Persson IM, Deyhle R Jr, Tromba G, Bayat S, Alves F, Dullin C. J Synchrotron Radiat. 2025 May 1;32(Pt 3):678-689. doi: 10.1107/S1600577525001511. Epub 2025 Mar 26. PMID: 40138215.
Woche 19 (06.05. - 11.05)
The Lung Cancer Autochthonous Model Gene Expression Database Enables Cross-Study Comparisons of the Transcriptomic Landscapes Across Mouse Models. Cai L, Wu F, Zhou Q, Gao Y, Yao B, DeBerardinis RJ, Acquaah-Mensah GK, Aidinis V, Beane JE, Biswal S, Chen T, Concepcion-Crisol CP, Grüner BM, Jia D, Jones RA, Kurie JM, Lee MG, Lindahl P, Lissanu Y, Lorz C, MacPherson D, Martinelli R, Mazur PK, Mazzilli SA, Mii S, Moll HP, Moorehead RA, Morrisey EE, Ng SR, Oser MG, Pandiri AR, Powell CA, Ramadori G, Santos M, Snyder EL, Sotillo R, Su KY, Taki T, Taparra K, Tran PT, Xia Y, van Veen JE, Winslow MM, Xiao G, Rudin CM, Oliver TG, Xie Y, Minna JD. Cancer Res. 2025 Apr 29:OF1-OF15. doi: 10.1158/0008-5472.CAN-24-1607. Epub ahead of print. PMID: 40298430.
Progress of personalized medicine of cystic fibrosis in the times of efficient CFTR modulators. Tümmler B, Pallenberg ST, Dittrich AM, Graeber SY, Naehrlich L, Sommerburg O, Mall MA. Mol Cell Pediatr. 2025 May 5;12(1):6. doi: 10.1186/s40348-025-00194-0. PMID: 40320452.
SARS-CoV-2 Vaccination in Primary Humoral Immunodeficiency: Experience from a German Lung Clinic. Rosendahl S, Trudzinski FC, Polke M, Herth FJF, Kreuter M, Giese T. Respiration. 2025;104(5):349-359. doi: 10.1159/000543146. Epub 2024 Dec 19. PMID: 39701048.
Estimated annual healthcare costs after acute pulmonary embolism: results from a prospective multicentre cohort study. Mohr K, Mildenberger P, Neusius T, Christodoulou KC, Farmakis IT, Kaier K, Barco S, Klok FA, Hobohm L, Keller K, Becker D, Abele C, Bruch L, Ewert R, Schmidtmann I, Wild PS, Rosenkranz S, Konstantinides SV, Binder H, Valerio L; FOCUS Investigators. Eur Heart J Qual Care Clin Outcomes. 2025 May 1;11(3):334-342. doi: 10.1093/ehjqcco/qcae050. PMID: 38950900; PMCID: PMC12045087.
SMAD2 linker phosphorylation impacts overall survival, proliferation, TGFβ1-dependent gene expression and pluripotency-related proteins in NSCLC. Nitschkowski D, Vierbuchen T, Heine H, Behrends J, Reiling N, Reck M, Rabe KF, Kugler C, Ammerpohl O, Drömann D, Muley T, Kriegsmann M, Stathopoulos GT, Arendt KAM, Goldmann T, Marwitz S. Br J Cancer. 2025 May 3. doi: 10.1038/s41416-025-02970-1. Epub ahead of print. PMID: 40319202.
Woche 18 (28.04 - 04.05)
Phase 3 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis. Chalmers JD, Burgel PR, Daley CL, De Soyza A, Haworth CS, Mauger D, Loebinger MR, McShane PJ, Ringshausen FC, Blasi F, Shteinberg M, Mange K, Teper A, Fernandez C, Zambrano M, Fan C, Zhang X, Metersky ML; ASPEN Investigators. N Engl J Med. 2025 Apr 24;392(16):1569-1581. doi: 10.1056/NEJMoa2411664. PMID: 40267423.
Woche 17 (21.04 - 27.04)
Ultrasound-guided transbronchial biopsy in the diagnosis of fibrosing mediastinitis-associated pulmonary hypertension. Zhang Y, Song HX, Qi YJ, Sun NN, Huang ZS, Fu WL, Zhang J, Herth FJF, Fan Y. Orphanet J Rare Dis. 2025 Apr 15;20(1):180. doi: 10.1186/s13023-025-03695-3. PMID: 40234923; PMCID: PMC12001500.
The identification and prediction of lung adenocarcinoma prognosis using a novel gene signature associated with DNA replication. Wu X, Xu Q, Aiyiti P, Meng D, Zhang J, Citarella F, Christopoulos P, Liu T, Duan W. Transl Cancer Res. 2025 Mar 30;14(3):1971-1981. doi: 10.21037/tcr-2024-2536. Epub 2025 Mar 27. PMID: 40224989; PMCID: PMC11985211.
Trends in Overall Survival in Lung Adenocarcinoma with EFGR Mutation, KRAS Mutation, or No Mutation. Faehling M, Fallscheer S, Schwenk B, Seifarth H, Sträter J, Lengerke C, Christopoulos P. Cancers (Basel). 2025 Apr 5;17(7):1237. doi: 10.3390/cancers17071237. PMID: 40227775; PMCID: PMC11988053.
Quantitative MRI detects delayed perfusion and impact of bronchial artery dilatation on pulmonary circulation in patients with cystic fibrosis. Leutz-Schmidt P, Grolig J, Wucherpfennig L, Sommerburg O, Eichinger M, Wege S, Graeber SY, Schenk JP, Alrajab A, Kauczor HU, Stahl M, Mall MA, Koeppe A, Nestler B, Selzer M, Triphan SMF, Wielpütz MO. Eur Radiol. 2025 Apr 16. doi: 10.1007/s00330-025-11589-y. Epub ahead of print. PMID: 40240556.
Woche 16 (14.04 - 20.04)
Longitudinal MRI in comparison to low-dose CT for follow-up of incidental pulmonary nodules in patients with COPD-a nationwide multicenter trial. Zhu L, Li Q, von Stackelberg O, Triphan SMF, Biederer J, Weinheimer O, Eichinger M, Vogelmeier CF, Jörres RA, Kauczor HU, Heußel CP, Jobst BJ, Yu H, Wielpütz MO; COSYCONET study group. Eur Radiol. 2025 Apr 13. doi: 10.1007/s00330-025-11567-4. Epub ahead of print. PMID: 40221941.
Association between socioeconomic position and lung cancer incidence in 16 countries: a prospective cohort consortium study. Onwuka JU, Zahed H, Feng X, Alcala K, Erhunmwunsee L, Williams RM, Aldrich MC, Ahluwalia JS, Albanes D, Arslan AA, Bassett JK, Brennan P, Cai Q, Chen C, Dimou N, Ferrari P, Freedman ND, Huang WY, Jones ME, Jones MR, Kaaks R, Koh WP, Langhammer A, Liao LM, Malekzadeh R, Milne RL, Rohan TE, Sánchez MJ, Sheikh M, Sinha R, Shu XO, Stevens VL, Tinker LF, Visvanathan K, Wang Y, Wang R, Weinstein SJ, White E, Yuan JM, Zheng W, Johansson M, Robbins HA. EClinicalMedicine. 2025 Mar 24;82:103152. doi: 10.1016/j.eclinm.2025.103152. PMID: 40212049; PMCID: PMC11985077.
Lessons Learned: Risk Factors and Clinical Impact of Severe Pneumothorax After Endoscopic Lung Volume Reduction With Endobronchial Valves. Brock JM, Dittrich SA, Eichhorn F, Schlamp K, Kontogianni K, Herth FJF. Chest. 2025 Apr;167(4):1012-1023. doi: 10.1016/j.chest.2024.10.045. Epub 2024 Nov 8. PMID: 39521377.
A Multidimensional Approach to the Management of Patients in Prolonged Weaning from Mechanical Ventilation: The Concept of Treatable Traits - A Narrative Review. Trudzinski FC, Neetz B, Dahlhoff JC, Wilkens FM, Katzenschlager S, Fähndrich S, Kempa A, Neurohr C, Schneider A, Joves B, Sommerwerck U, Eberhardt R, Bornitz F, Herth FJF, Michels-Zetsche JD. Respiration. 2025;104(4):240-254. doi: 10.1159/000541965. Epub 2024 Oct 30. PMID: 39476811.
Woche 15 (07.04. - 13.04.)
Sex-specific aspects in a population of patients undergoing evaluation for interstitial lung disease with transbronchial cryobiopsy. Reinhard J, Polke M, Buschulte K, Eichinger M, Heußel CP, Güttlein M, Michels-Zetsche JD, Wielpütz MO, Kahnert K, Kontogianni K, Klotz LV, Allgäuer M, Herth FJ, Eberhardt R, Kreuter M, Trudzinski FC. Sci Rep. 2025 Apr 5;15(1):11730. doi: 10.1038/s41598-025-94575-0. PMID: 40188253; PMCID: PMC11972388.
The established chest MRI score for cystic fibrosis can be applied to contrast agent-free matrix pencil decomposition functional MRI: a multireader analysis. Steinke E, Bauman G, Steffen IG, Schobert IT, Thee S, Syunyaeva Z, Roehmel J, Posch H, Fahlenkamp UL, Scale C, Veldhoen S, Bieri O, Wielpütz MO, Mall MA, Stahl M, Doellinger F. Front Med (Lausanne). 2025 Mar 18;12:1527843. doi: 10.3389/fmed.2025.1527843. PMID: 40171501; PMCID: PMC11958188.
17 Jahre WeanNet – ein Rück- und Ausblick [17 years of WeanNet - review and perspective]. Geiseler J, Westhoff M, Trudzinski FC, Sommwerck U, Randerath W. Pneumologie. 2025 Apr 1. German. doi: 10.1055/a-2546-1496. Epub ahead of print. PMID: 40169129.
Oscillometry-defined Small Airway Dysfunction in Tobacco-exposed Adults with Impaired or Preserved Airflow. Abdo M, Watz H, Trinkmann F, Bohnet S, Guess MAM, Roeben J, May K, Reck M, Bollmann BA, Stiebeler S, Dettmer S, Waschki B, Rabe KF, Franzen KF, Vogel-Claussen J. Am J Respir Crit Care Med. 2025 Apr 2. doi: 10.1164/rccm.202501-0028OC. Epub ahead of print. PMID: 40173271.
Update der S3-Leitlinie: Epidemiologie, Diagnostik und Therapie erwachsener Patienten mit nosokomialer Pneumonie [Epidemiology, diagnosis and treatment of adult patients with nosocomial pneumonia]. Rademacher J, Ewig S, Grabein B, Nachtigall I, Abele-Horn M, Deja M, Gaßner M, Gatermann S, Geffers C, Gerlach H, Hagel S, Heußel CP, Kluge S, Kolditz M, Kramme E, Kühl H, Panning M, Rath PM, Rohde G, Schaaf B, Salzer HJF, Schreiter D, Schweisfurth H, Unverzagt S, Weigand MA, Welte T, Pletz MW; Deutsche Gesellschaft für Pneumologie und Beatmungsmedizin e.V. (DGP) (federführende Fachgesellschaft) und; Deutsche Gesellschaft für Anästhesiologie und Intensivmedizin e.V. (DGAI); Deutsche Gesellschaft für Chirurgie e.V. (DGCH); Deutsche Gesellschaft für Hygiene und Mikrobiologie e.V. (DGHM); Deutsche Gesellschaft für Infektiologie e.V. (DGI); Deutsche Gesellschaft für Internistische Intensivmedizin und Notfallmedizin e.V. (DGIIN); Deutsche Gesellschaft für Innere Medizin e.V. (DGIM); Deutsche Röntgengesellschaft, Gesellschaft für Medizinische Radiologie e.V. (DRG); Deutsche Sepsis-Gesellschaft e.V. (DSG); Gesellschaft für Virologie e.V. (GfV); Paul-Ehrlich-Gesellschaft für Infektionstherapie e.V. (PEG); Deutsche Sepsis-Hilfe e.V. (DSH). Pneumologie. 2025 Apr 1. German. doi: 10.1055/a-2541-9872. Epub ahead of print. PMID: 40169124.
Kontextfaktoren für die Durchführung endoskopischer Untersuchungen als stationäre Leistung bei Erwachsenen [Context factors for performing endoscopic examinations as an inpatient service in adults]. Krist J, Hagmeyer L, Schoenfeld N, Darwiche K, Brock JM, Piening A, Skowasch D, Randerath W, Bauer T, Hübner RH. Pneumologie. 2025 Apr 1. German. doi: 10.1055/a-2567-4715. Epub ahead of print. PMID: 40169127.
Kongresse der Deutschen und Österreichischen Gesellschaft für Pneumologie 2024: Highlights aus dem Bereich der Interventionellen Pneumologie [DGP and ÖGP Congress 2024: Highlights from Interventional Pulmonology]. Dittrich AS, Murauer G, Meilinger M, Hübner RH, Brock JM, Gompelmann D. Pneumologie. 2025 Apr 1. German. doi: 10.1055/a-2547-5031. Epub ahead of print. PMID: 40169128.
Woche 14 (31.03. - 06.04)
NeoTRACK trial: Neoadjuvant TiRagolumab, Atezolizumab and Chemotherapy - dissection of IO- efficacy in NSCLC by longitudinal tracKing - protocol of a non-randomised, open-label, single-arm, phase II study. Roesch RM, Schnorbach J, Klotz LV, Griffo R, Thomas M, Stenzinger A, Christopoulos P, Allgaeuer M, Schneider M, Schuler M, Wiesweg M, Schramm A, Bölükbas S, Doerr F, Hegedüs B, Cvetkovic J, Kirchner M, Eichhorn ME, Winter H, Bozorgmehr F, Eichhorn F. BMJ Open. 2025 Mar 27;15(3):e096617. doi: 10.1136/bmjopen-2024-096617. PMID: 40147985; PMCID: PMC11956294.
Automated CT Image Processing for the Diagnosis, Prediction, and Differentiation of Phenotypes in Chronic Lung Allograft Dysfunction After Lung Transplantation. Kuhnert S, Halim N, Sommerlad J, Gall H, Yogeswaran A, Roller FC, Krombach G, Reichert M, Askevold I, Hecker A, Koch C, Seeger W, Mayer K, Weinheimer O, Hecker M. Clin Transplant. 2026 Apr;39(4):e70137. doi: 10.1111/ctr.70137. PMID: 40136064.
Pathogenic SMAD6 variants in patients with idiopathic and complex congenital heart disease associated pulmonary arterial hypertension. Karl S, Grünig E, Shaukat M, Held M, Apitz C, von Scheidt F, Geiger R, Halank M, Olsson KM, Hoeper MM, Kamp JC, Kovacs G, Olschewski H, Seyfarth HJ, Milger K, Ewert R, Klose H, Egenlauf B, Xanthouli P, Hinderhofer K, Eichstaedt CA. NPJ Genom Med. 2025 Mar 25;10(1):28. doi: 10.1038/s41525-025-00484-6. PMID: 40133303; PMCID: PMC11937313.
Woche 13 (24.03 - 30.03)
Diagnosis and Treatment of Bronchial Dieulofy's Disease: A Case Series. Yang H, Liu Y, Lou J, Chen X, Zhang Q, Zhang X, Herth FJF. Respiration. 2025 Mar 21:1-11. doi: 10.1159/000545261. Epub ahead of print. PMID: 40122045.
Single-Tablet Combination Therapy of Macitentan/Tadalafil for Patients with Pulmonary Arterial Hypertension: Qualitative Interview Study of the A DUE Phase 3 Trial. Fan F, Davis S, Burbridge C, Chin K, Friberg M, Grünig E, Hughes M, Jansa P, Linder J, Rafalski J, Rodriguez AA, Randall JA. Adv Ther. 2025 Mar 18. doi: 10.1007/s12325-025-03159-x. Epub ahead of print. PMID: 40100308.
Efficacy and safety of sotatercept across ranges of cardiac index in patients with pulmonary arterial hypertension: A pooled analysis of PULSAR and STELLAR. Gomberg-Maitland M, Badesch DB, Gibbs JSR, Grünig E, Hoeper MM, Humbert M, Kopeć G, McLaughlin VV, Meyer G, Olsson KM, Preston IR, Rosenkranz S, Souza R, Waxman AB, Perchenet L, Strait J, Xing A, Johnson-Levonas AO, Cornell AG, de Oliveira Pena J, Ardeschir Ghofrani H. J Heart Lung Transplant. 2025 Apr;44(4):609-624. doi: 10.1016/j.healun.2024.11.037. Epub 2024 Dec 5. PMID: 39645016.
Web-based educational tools and decision aids for patients with advanced cancer: A systematic review. Ullrich P, Voß H, Unsöld L, Thomas M, Villalobos M. Patient Educ Couns. 2025 May;134:108706. doi: 10.1016/j.pec.2025.108706. Epub 2025 Feb 14. PMID: 39970486.
Woche 12 (17.03 - 23.03)
Precision oncology - Guideline of the Austrian, German and Swiss Societies for hematology and medical oncology. Rieke DT, Bitzer M, Bleckmann A, Desuki A, Ernst T, Esposito I, Gerger A, Glimm H, Horak P, Hübschmann D, Illert AL, Kunzmann V, Loges S, Pretzell I, Schmitz K, Seeber A, Söhlke B, Wicki A, Wolf J, Maschmeyer G. Eur J Cancer. 2025 Feb 28;220:115331. doi: 10.1016/j.ejca.2025.115331. Epub ahead of print. PMID: 40058270.
A new era for EGFR exon20 targeting in non-small cell lung cancer. Christopoulos P. Chin Clin Oncol. 2025 Feb;14(1):14. doi: 10.21037/cco-24-102. PMID: 40081390.
Acquisition and Handling of Endobronchial Ultrasound Transbronchial Needle Samples: An American College of Chest Physicians Clinical Practice Guideline. Gilbert CR, Dust C, Argento AC, Feller-Kopman D, Gonzalez AV, Herth F, Iaccarino JM, Illei P, O'Neil K, Pastis N, Rivera MP, Sholl L, Silvestri GA, Thiboutot J, Wahidi MM, Yasafuku K, Yarmus LB. . Chest. 2025 Mar;167(3):899-909. doi: 10.1016/j.chest.2024.08.056. Epub 2024 Sep 27. PMID: 39343294.
Woche 11 (10.03. - 16.03.)
Low-coverage whole genome sequencing of cell-free DNA to predict and track immunotherapy response in advanced non-small cell lung cancer. Janke F, Gasser M, Angeles AK, Riediger AL, Görtz M, Appenheimer L, Laut AK, Ogrodnik S, Gerhardt S, Stenzinger A, Schneider MA, Thomas M, Christopoulos P, Sültmann H. J Exp Clin Cancer Res. 2025 Mar 8;44(1):87. doi: 10.1186/s13046-025-03348-0. PMID: 40055810; PMCID: PMC11889826.
Effects of cigarette-derived compounds on the spread of antimicrobial resistance in artificial human lung sputum medium, simulated environmental media and wastewater. Fang P, Konyali D, Fischer E, Mayer RP, Huang J, Elena AX, Orzechowski GH, Tony-Odigie A, Kneis D, Dalpke A, Krebs P, Li B, Berendonk TU, Klümper U. Environ Health Perspect. 2025 Mar 3. doi: 10.1289/EHP14704. Epub ahead of print. PMID: 40032488.
Sex-Specific Differences in Echocardiographic Parameters of Risk Stratification in Pulmonary Arterial Hypertension. Benjamin N, Schiffer V, Resag C, Xanthouli P, Braun M, Harutyunova S, Eichstaedt CA, Egenlauf B, Marra AM, Bossone E, Cittadini A, Kiely DG, Grünig E. J Am Soc Echocardiogr. 2025 Mar;38(3):273-285. doi: 10.1016/j.echo.2024.11.015. Epub 2024 Dec 18. PMID: 39706311.
Mono and combination therapies in pulmonary arterial hypertension patients with comorbidities: A COMPERA analysis. Skowasch D, Pausch C, Huscher D, Pittrow D, Wede J, Kreimendahl F, Rosenkranz S, Beckmann S, Held M, Grünig E, Ghofrani HA, Klose H, Skride A, Halank M, Stadler S, Delcroix M, Vonk-Noordegraaf A, Ewert R, Kopec G, Hoeper MM, Olsson KM. ESC Heart Fail. 2025 Mar 4. doi: 10.1002/ehf2.15254. Epub ahead of print. PMID: 40037846.
Costs of biomarker testing in advanced non-small cell lung cancer: a global study comparing next-generation sequencing and single-gene testing. Malapelle U, Chen CC, de Álava E, Hofman P, Kazdal D, Kim TJ, Lim TKH, Ryška A, Saetta AA, Schuuring E, Troncone G, Biscuola M, Chen YL, Tan GS, Marquette CH, Michelli M, Ter Elst A, Vošmiková H, Kapp J, Gonzalez-McQuire S, Giannopoulou A, Franzini JM, Aramburu VLR, Baggi A, Stenzinger A. J Pathol Clin Res. 2025 Mar;11(2):e70018. doi: 10.1002/2056-4538.70018. PMID: 40052485; PMCID: PMC11886603.
Global functional genomics reveals GRK5 as a cystic fibrosis therapeutic target synergistic with current modulators. Botelho HM, Lopes-Pacheco M, Pinto MC, Railean V, Pankonien I, Caleiro MF, Clarke LA, Cachatra V, Neumann B, Tischer C, Moiteiro C, Ousingsawat J, Kunzelmann K, Pepperkok R, Amaral MD. iScience. 2025 Feb 1;28(3):111942. doi: 10.1016/j.isci.2025.111942. PMID: 40040803; PMCID: PMC11876911.
Woche 10 (03.03. - 09.03.)
Pulmonary arteriovenous malformation causing lung sequestration and media infarction: a case report. Griffo R, Klotz LV, Brendel L, Rösch R, Niedermaier B, Schlamp K, Kriegsmann M, Eichhorn MM, Winter H. Front Med (Lausanne). 2025 Feb 11;12:1490820. doi: 10.3389/fmed.2025.1490820. PMID: 40007589; PMCID: PMC11850261.
Die Rolle der Atmungstherapeuten im Weaning von der invasiven Beatmung – Eine Tätigkeitsbeschreibung aus einem zertifizierten Weaning-Zentrum [Role of respiratory therapists in weaning patients from invasive mechanical ventilation: a description of their responsibilities from a certified weaning centre]. Neetz B, Iberl G, Kraus N, Weißmann C, Bornitz F, Müller MM, Reinhardt L, Herth F, Michels J, Trudzinski F. Pneumologie. 2025 Feb 25. German. doi: 10.1055/a-2529-6367. Epub ahead of print. PMID: 39999973.
Woche 9 (24.02. - 02.03.)
Intracellular and extracellular activities of V-domain Ig-containing suppressor of T cell activation (VISTA) modulated by immunosuppressive factors of tumour microenvironment. Abooali M, Schlichtner S, Lei X, Aliu N, Ruggiero S, Loges S, Ziegler M, Hertel F, Volckmar AL, Stenzinger A, Christopoulos P, Thomas M, Klenova E, Meyer NH, Boussios S, Heaton N, Zen Y, Zamalloa A, Chokshi S, Urbani L, Richard S, Kirubendran K, Hussain R, Siligardi G, Cholewa D, Berger SM, Yasinska IM, Fasler-Kan E, Sumbayev VV. Cancer Lett. 2025 Feb 19:217581. doi: 10.1016/j.canlet.2025.217581. Epub ahead of print. PMID: 39983894.
Increasing challenges of general practitioner-oncologist interaction in end-of-life communication: a qualitative study. Villalobos M, Korezelidou A, Unsöld L, Deis N, Thomas M, Siegle A. BMC Palliat Care. 2025 Feb 20;24(1):48. doi: 10.1186/s12904-025-01690-w. PMID: 39979926; PMCID: PMC11841224.
Woche 8 (17.02 - 23.02)
Chancen und Barrieren des IPReG für die außerklinische Intensivpflege : Eine explorative Interviewstudie mit Kostenträgern und gesundheitspolitischen Akteuren im Rahmen der „PRiVENT“-Studie [Opportunities and barriers of IPReG for out-of-hospital intensive care : Explorative interview study with payers and health policy stakeholders as part of the PRiVENT study]. Biehler E, Fleischhauer T, Fuchs GE, Forstner J, Weis A, von Schumann S, Michels-Zetsche JD, Trudzinski FC, Herth FJF, Szecsenyi J, Wensing M. Med Klin Intensivmed Notfmed. 2025 Feb 10. German. doi: 10.1007/s00063-025-01247-y. Epub ahead of print. PMID: 39928157.
Neue Indikationen in der Schnittbilddiagnostik der Aorta [New innovations in cross-sectional imaging diagnostics of the aorta]. Melzig C, Böckler D, Kauczor HU, Wielpütz MO, Bischoff MS. Radiologie (Heidelb). 2025 Feb 13. German. doi: 10.1007/s00117-025-01424-2. Epub ahead of print. PMID: 39945846.
Woche 7 (10.02 - 16.02)
Myofibroblasts emerge during alveolar regeneration following influenza-virus-induced lung injury. Khadim A, Kiliaris G, Vazquez-Armendariz AI, Procida-Kowalski T, Glaser D, Bartkuhn M, Malik T, Chu X, Moiseenko A, Kuznetsova I, Ahmadvand N, Lingampally A, Hadzic S, Alexopoulos I, Chen Y, Günther A, Behr J, Neumann J, Schiller HB, Li X, Weissmann N, Braun T, Seeger W, Wygrecka M, Morty RE, Herold S, El Agha E. Cell Rep. 2025 Feb 3;44(2):115248. doi: 10.1016/j.celrep.2025.115248. Epub ahead of print. PMID: 39903667.
Outcomes of Pembrolizumab plus chemotherapy for patients with metastatic non-squamous NSCLC: Real-world evidence. Surovtsova I, Herth FJF, Kokh DB, Morakis P. Pulmonology. 2025 Dec 31;31(1):2457856. doi: 10.1080/25310429.2025.2457856. Epub 2025 Feb 5. PMID: 39907049.
Proposal of real-world solutions for the implementation of predictive biomarker testing in patients with operable non-small cell lung cancer. Hofman P, Christopoulos P, D'Haene N, Gosney J, Normanno N, Schuuring E, Tsao MS, Quinn C, Russell J, Keating KE, López-Ríos F. Lung Cancer. 2025 Jan 26;201:108107. doi: 10.1016/j.lungcan.2025.108107. Epub ahead of print. PMID: 39904223.
Woche 6 (03.02 - 09.02)
Risk factors for survival after lung transplantation in cystic fibrosis: impact of colonization with multidrug-resistant strains of Pseudomonas aeruginosa. Weingard B, Becker SL, Schneitler S, Trudzinski FC, Bals R, Wilkens H, Langer F. Infection. 2025 Jan 30. doi: 10.1007/s15010-025-02478-z. Epub ahead of print. PMID: 39883262.
Artificial intelligence for diagnosis and predictive biomarkers in Non-Small cell lung cancer Patients: New promises but also new hurdles for the pathologist. Hofman P, Ourailidis I, Romanovsky E, Ilié M, Budczies J, Stenzinger A. Lung Cancer. 2025 Jan 27;200:108110. doi: 10.1016/j.lungcan.2025.108110. Epub ahead of print. PMID: 39879785.
Efficacy and safety of the activin signalling inhibitor, sotatercept, in a pooled analysis of PULSAR and STELLAR studies. Hoeper MM, Gomberg-Maitland M, Badesch DB, Gibbs JSR, Grünig E, Kopeć G, McLaughlin VV, Meyer G, Olsson KM, Preston IR, Rosenkranz S, Souza R, Waxman AB, Perchenet L, Strait J, Xing A, Manimaran S, Wang X, Miller B, Cornell AG, de Oliveira Pena J, Ghofrani HA, Humbert M. Eur Respir J. 2025 Jan 30:2401424. doi: 10.1183/13993003.01424-2024. Epub ahead of print. PMID: 39884760.
Woche 5 (27.01 - 02.02)
MOMENT registry: Patients with advanced non-small-cell lung cancer harboring MET exon 14 skipping treated with systemic therapy. Thomas M, Christopoulos P, Iams WT, Mazières J, Cortot AB, Peled N, Minuti G, Smit EF, Audhuy F, Berghoff K, Eggleton SP, Fries F, Hildenbrand M, Liu P, Mahmoudpour SH, Menzel C, Oksen D. J Comp Eff Res. 2025 Feb;14(2):e240127. doi: 10.57264/cer-2024-0127. Epub 2025 Jan 21. PMID: 39836056.
Reply to Martin and Grasemann: Is There a Role for Lumacaftor/Ivacaftor in Young Children with Cystic Fibrosis? Stahl M, Röhmel J, Wielpütz MO, Mall MA. Ann Am Thorac Soc. 2025 Jan 21. doi: 10.1513/AnnalsATS.202411-1237LE. Epub ahead of print. PMID: 39836962.
Comparison of the diagnostic performance of non-contrast MR angiography and planar V/Q scintigraphy for pulmonary embolism: a systematic review and meta-analysis. Silva RF, Zanon M, Ackman JB, Forte GC, Altmayer S, Biederer J, Bergmann LL, Andrade RGF, Hochhegger B. Eur Radiol. 2025 Jan 26. doi: 10.1007/s00330-025-11366-x. Epub ahead of print. PMID: 39863727.
Woche 4 (20.01. - 26.01)
Intratumor Heterogeneity Predicts Prognosis in Lepidic Predominant Lung Adenocarcinoma. Niedermaier B, Allgäuer M, Muley T, Schneider MA, Eichhorn ME, Winter H, Klotz LV. Thorac Cancer. 2025 Jan;16(1):e15536. doi: 10.1111/1759-7714.15536. PMID: 39807578; PMCID: PMC11729388.
Woche 3 (13.01. - 19.01)
A reproducibility study on invasion in small pulmonary adenocarcinoma according to the WHO and a modified classification, supported by biomarkers. Thunnissen E, Blaauwgeers H, Filipello F, Lissenberg-Witte B, Minami Y, Noguchi M, Quesne JL, Papotti MG, Flieder DB, Pelosi G, Sansano I, Berezowska S, Ryška A, Brcic L, Motoi N, Nakatani Y, Kuempers C, Hofman P, Hofman V, Dale VG, Rossi G, Ambrosi F, Matsubara D, Ishikawa Y, Weynand B, Calabrese F, Pezzuto F, Kern I, Nicholson S, Mutka A, Dacic S, Beasley MB, Arrigoni G, Timens W, Ooft M, Brinkhuis M, Bulkmans N, Britstra R, Vreuls W, Jones KD, von der Thüsen JH, Hager H, Perner S, Moore D, Leonte DG, Al-Janabi S, Schønau A, Neumann O, Kluck K, Ourailidis I, Ball M, Budczies J, Kazdal D, Stenzinger A. Lung Cancer. 2024 Dec 19;199:108060. doi: 10.1016/j.lungcan.2024.108060. Epub ahead of print. PMID: 39793325.
Automated volumetry of core and peel intrapulmonary vasculature on computed tomography angiography for non-invasive estimation of hemodynamics in patients with pulmonary hypertension (2022 updated hemodynamic definition). Melzig C, Weinheimer O, Egenlauf B, Do TD, Wielpütz MO, Grünig E, Kauczor HU, Heussel CP, Rengier F. Cardiovasc Diagn Ther. 2024 Dec 31;14(6):1083-1095. doi: 10.21037/cdt-24-293. Epub 2024 Dec 19. PMID: 39790187; PMCID: PMC11707475.
Low tumour interleukin-1β expression predicts a limited effect of adjuvant platinum-based chemotherapy for patients with completely resected lung adenocarcinoma: An identification and validation study. Authors´reply. Safi S, Benner A, Beckhove P, Muley T. Pulmonology. 2025 Dec 31;31(1):2447637. doi: 10.1080/25310429.2024.2447637. Epub 2025 Jan 8. PMID: 39773309.
Outcome and safety 90 days after combined airway valve treatment of the right upper and middle lobes in patients with severe pulmonary emphysema. Dittrich AS, De Pace CC, Brock JM, Trudzinski F, Heussel CP, Eberhardt R, Herth FJF, Kontogianni K. Respir Res. 2025 Jan 6;26(1):4. doi: 10.1186/s12931-024-03069-6. PMID: 39762833; PMCID: PMC11706069.
Woche 2 (06.01. - 12.01.)
Malignancy risk stratification for pulmonary nodules: comparing a deep learning approach to multiparametric statistical models in different disease groups. Piskorski L, Debic M, von Stackelberg O, Schlamp K, Welzel L, Weinheimer O, Peters AA, Wielpütz MO, Frauenfelder T, Kauczor HU, Heußel CP, Kroschke J. Eur Radiol. 2025 Jan 2. doi: 10.1007/s00330-024-11256-8. Epub ahead of print. PMID: 39747589.
Woche 1 (30.12.24 - 05.01.25)
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